Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AZ97_LEIMU

TriTrypDb:

LmxM.27.1945

Length:

259

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AZ97

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZ97

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	121	123	PF00675	0.685
CLV_NRD_NRD_1	166	168	PF00675	0.466
CLV_NRD_NRD_1	19	21	PF00675	0.616
CLV_NRD_NRD_1	190	192	PF00675	0.544
CLV_PCSK_FUR_1	119	123	PF00082	0.691
CLV_PCSK_KEX2_1	121	123	PF00082	0.685
CLV_PCSK_KEX2_1	166	168	PF00082	0.466
CLV_PCSK_KEX2_1	190	192	PF00082	0.552
CLV_PCSK_SKI1_1	173	177	PF00082	0.505
DEG_Nend_Nbox_1	1	3	PF02207	0.605
DEG_SPOP_SBC_1	85	89	PF00917	0.651
DOC_MAPK_DCC_7	34	42	PF00069	0.458
DOC_MAPK_MEF2A_6	34	42	PF00069	0.458
DOC_PP4_FxxP_1	68	71	PF00568	0.583
DOC_USP7_MATH_1	41	45	PF00917	0.586
DOC_USP7_MATH_1	53	57	PF00917	0.739
DOC_USP7_MATH_1	71	75	PF00917	0.512
DOC_USP7_MATH_1	85	89	PF00917	0.605
DOC_USP7_MATH_1	97	101	PF00917	0.681
DOC_WW_Pin1_4	67	72	PF00397	0.751
DOC_WW_Pin1_4	77	82	PF00397	0.636
LIG_14-3-3_CanoR_1	244	254	PF00244	0.630
LIG_14-3-3_CanoR_1	52	62	PF00244	0.639
LIG_14-3-3_CanoR_1	64	71	PF00244	0.627
LIG_BRCT_BRCA1_1	64	68	PF00533	0.520
LIG_FHA_1	253	259	PF00498	0.644
LIG_LIR_Apic_2	65	71	PF02991	0.653
LIG_LIR_Gen_1	248	258	PF02991	0.632
LIG_LIR_Nem_3	248	254	PF02991	0.633
LIG_SH2_CRK	16	20	PF00017	0.652
LIG_SH2_CRK	251	255	PF00017	0.528
LIG_SH2_STAP1	216	220	PF00017	0.602
LIG_SH2_STAT5	216	219	PF00017	0.616
LIG_SH3_1	33	39	PF00018	0.683
LIG_SH3_3	102	108	PF00018	0.755
LIG_SH3_3	33	39	PF00018	0.683
LIG_TRFH_1	9	13	PF08558	0.692
LIG_TYR_ITIM	14	19	PF00017	0.715
LIG_WW_1	30	33	PF00397	0.569
MOD_CK1_1	63	69	PF00069	0.636
MOD_CK1_1	74	80	PF00069	0.587
MOD_CK1_1	84	90	PF00069	0.634
MOD_CK2_1	198	204	PF00069	0.653
MOD_CK2_1	41	47	PF00069	0.668
MOD_GlcNHglycan	123	126	PF01048	0.734
MOD_GlcNHglycan	65	68	PF01048	0.585
MOD_GlcNHglycan	99	102	PF01048	0.695
MOD_GSK3_1	169	176	PF00069	0.552
MOD_GSK3_1	63	70	PF00069	0.627
MOD_GSK3_1	76	83	PF00069	0.602
MOD_N-GLC_1	246	251	PF02516	0.633
MOD_NEK2_1	177	182	PF00069	0.590
MOD_NEK2_1	62	67	PF00069	0.687
MOD_PKA_1	121	127	PF00069	0.678
MOD_PKA_2	121	127	PF00069	0.678
MOD_PKA_2	63	69	PF00069	0.589
MOD_PKB_1	119	127	PF00069	0.684
MOD_PKB_1	167	175	PF00069	0.479
MOD_Plk_1	173	179	PF00069	0.560
MOD_ProDKin_1	67	73	PF00069	0.748
MOD_ProDKin_1	77	83	PF00069	0.637
TRG_DiLeu_BaEn_1	219	224	PF01217	0.518
TRG_ENDOCYTIC_2	16	19	PF00928	0.719
TRG_ENDOCYTIC_2	251	254	PF00928	0.534
TRG_ER_diArg_1	118	121	PF00400	0.693
TRG_ER_diArg_1	190	192	PF00400	0.602
TRG_ER_diArg_1	231	234	PF00400	0.520
TRG_ER_diArg_1	238	241	PF00400	0.645
TRG_Pf-PMV_PEXEL_1	240	245	PF00026	0.540

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0NR64	Trypanosomatidae	31%	100%
A0A3S7X0W4	Leishmania donovani	90%	100%
A4HFW8	Leishmania braziliensis	73%	98%
A4I301	Leishmania infantum	88%	100%
E9ADH3	Leishmania major	90%	100%