Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AZ96_LEIMU

TriTrypDb:

LmxM.27.1930

Length:

354

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5

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Expansion

Sequence features

E9AZ96

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZ96

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	202	204	PF00675	0.389
CLV_NRD_NRD_1	61	63	PF00675	0.392
CLV_NRD_NRD_1	94	96	PF00675	0.594
CLV_PCSK_FUR_1	200	204	PF00082	0.402
CLV_PCSK_KEX2_1	202	204	PF00082	0.389
CLV_PCSK_KEX2_1	61	63	PF00082	0.390
CLV_PCSK_KEX2_1	93	95	PF00082	0.605
CLV_PCSK_PC1ET2_1	93	95	PF00082	0.605
CLV_PCSK_SKI1_1	157	161	PF00082	0.442
CLV_PCSK_SKI1_1	61	65	PF00082	0.428

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IQ36	Leishmania donovani	80%	100%
A4HFW7	Leishmania braziliensis	49%	100%
A4I300	Leishmania infantum	80%	100%
E9ADH2	Leishmania major	71%	100%

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