Golgi apparatus membrane protein TVP23 homolog

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Eukaryotic protein of unknown function (DUF846), putative

Species:

Leishmania mexicana

UniProt:

E9AZ93_LEIMU

TriTrypDb:

LmxM.27.1900

Length:

130

Annotations

LeishMANIAdb annotations

Homologous to Golgi proteins of other Eukaryotes

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

Expansion

Sequence features

E9AZ93

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZ93

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	81	83	PF00675	0.273
CLV_PCSK_KEX2_1	81	83	PF00082	0.278
DEG_Nend_UBRbox_1	1	4	PF02207	0.352
DOC_WW_Pin1_4	17	22	PF00397	0.352
LIG_deltaCOP1_diTrp_1	31	36	PF00928	0.434
LIG_FHA_1	11	17	PF00498	0.499
LIG_FHA_1	43	49	PF00498	0.197
LIG_LIR_Gen_1	45	54	PF02991	0.164
LIG_LIR_Nem_3	31	37	PF02991	0.348
LIG_LIR_Nem_3	45	49	PF02991	0.221
LIG_LIR_Nem_3	56	62	PF02991	0.368
LIG_PCNA_yPIPBox_3	79	92	PF02747	0.482
LIG_Pex14_2	74	78	PF04695	0.164
LIG_PTB_Apo_2	29	36	PF02174	0.352
LIG_SH2_GRB2like	30	33	PF00017	0.352
LIG_SH2_SRC	59	62	PF00017	0.164
LIG_SH2_STAP1	30	34	PF00017	0.352
LIG_SH2_STAT5	59	62	PF00017	0.164
LIG_SH2_STAT5	77	80	PF00017	0.348
LIG_SUMO_SIM_anti_2	45	51	PF11976	0.164
LIG_WRC_WIRS_1	106	111	PF05994	0.491
LIG_WRC_WIRS_1	54	59	PF05994	0.191
LIG_WRC_WIRS_1	88	93	PF05994	0.459
MOD_CK2_1	16	22	PF00069	0.352
MOD_CMANNOS	33	36	PF00535	0.164
MOD_GlcNHglycan	69	72	PF01048	0.200
MOD_GSK3_1	87	94	PF00069	0.463
MOD_N-GLC_1	116	121	PF02516	0.328
MOD_NEK2_1	35	40	PF00069	0.171
MOD_NEK2_1	91	96	PF00069	0.468
MOD_PIKK_1	10	16	PF00454	0.352
MOD_PIKK_1	91	97	PF00454	0.469
MOD_Plk_4	105	111	PF00069	0.639
MOD_Plk_4	42	48	PF00069	0.212
MOD_Plk_4	87	93	PF00069	0.459
MOD_ProDKin_1	17	23	PF00069	0.352
TRG_ENDOCYTIC_2	59	62	PF00928	0.370

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4JUW4	Bodo saltans	51%	71%
A1CIM7	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	29%	68%
A1CW41	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	31%	68%
A2Q9P5	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	29%	68%
A4RME3	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	35%	67%
A6SFL7	Botryotinia fuckeliana (strain B05.10)	32%	70%
B0Y4Q8	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	31%	68%
B2ALT5	Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383)	36%	68%
Q0CSZ7	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	32%	68%
Q0UV43	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	32%	67%
Q1E9X9	Coccidioides immitis (strain RS)	33%	69%
Q2UUK2	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	33%	67%
Q4WQJ5	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	31%	68%
Q6C7V5	Yarrowia lipolytica (strain CLIB 122 / E 150)	31%	72%
Q7SGB6	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	34%	68%
Q8LEK2	Arabidopsis thaliana	35%	70%