Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AZ63_LEIMU

TriTrypDb:

LmxM.27.1600

Length:

218

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AZ63

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZ63

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	200	202	PF00675	0.509
CLV_PCSK_FUR_1	198	202	PF00082	0.518
CLV_PCSK_KEX2_1	200	202	PF00082	0.509
CLV_PCSK_SKI1_1	154	158	PF00082	0.518
CLV_PCSK_SKI1_1	211	215	PF00082	0.537
DEG_APCC_DBOX_1	162	170	PF00400	0.483
DEG_APCC_DBOX_1	210	218	PF00400	0.558
DEG_SPOP_SBC_1	93	97	PF00917	0.545
DOC_CKS1_1	82	87	PF01111	0.611
DOC_CYCLIN_RxL_1	151	160	PF00134	0.537
DOC_CYCLIN_yCln2_LP_2	34	40	PF00134	0.499
DOC_MAPK_MEF2A_6	154	161	PF00069	0.529
DOC_PP2B_LxvP_1	34	37	PF13499	0.514
DOC_USP7_MATH_1	106	110	PF00917	0.643
DOC_USP7_MATH_1	27	31	PF00917	0.582
DOC_USP7_MATH_1	5	9	PF00917	0.582
DOC_WW_Pin1_4	81	86	PF00397	0.604
LIG_14-3-3_CanoR_1	139	148	PF00244	0.488
LIG_BIR_II_1	1	5	PF00653	0.630
LIG_BRCT_BRCA1_1	40	44	PF00533	0.492
LIG_BRCT_BRCA1_1	63	67	PF00533	0.533
LIG_FHA_1	33	39	PF00498	0.501
LIG_FHA_1	75	81	PF00498	0.550
LIG_FHA_2	169	175	PF00498	0.476
LIG_FHA_2	18	24	PF00498	0.384
LIG_FHA_2	210	216	PF00498	0.609
LIG_LIR_Gen_1	53	61	PF02991	0.502
LIG_LIR_Nem_3	143	148	PF02991	0.570
LIG_LIR_Nem_3	43	49	PF02991	0.522
LIG_LIR_Nem_3	53	57	PF02991	0.311
LIG_NRBOX	152	158	PF00104	0.505
LIG_PCNA_yPIPBox_3	200	214	PF02747	0.531
LIG_Pex14_2	40	44	PF04695	0.452
LIG_SH2_STAT5	141	144	PF00017	0.411
LIG_SH3_3	210	216	PF00018	0.538
LIG_SH3_3	79	85	PF00018	0.551
LIG_SUMO_SIM_anti_2	76	82	PF11976	0.580
LIG_WRC_WIRS_1	54	59	PF05994	0.466
MOD_CK1_1	109	115	PF00069	0.614
MOD_CK1_1	4	10	PF00069	0.653
MOD_CK1_1	56	62	PF00069	0.487
MOD_CK1_1	73	79	PF00069	0.446
MOD_GlcNHglycan	106	109	PF01048	0.664
MOD_GlcNHglycan	25	28	PF01048	0.462
MOD_GlcNHglycan	3	6	PF01048	0.639
MOD_GlcNHglycan	30	33	PF01048	0.479
MOD_GlcNHglycan	7	10	PF01048	0.552
MOD_GlcNHglycan	86	89	PF01048	0.536
MOD_GSK3_1	1	8	PF00069	0.711
MOD_GSK3_1	106	113	PF00069	0.586
MOD_GSK3_1	17	24	PF00069	0.439
MOD_GSK3_1	182	189	PF00069	0.674
MOD_GSK3_1	28	35	PF00069	0.493
MOD_GSK3_1	36	43	PF00069	0.399
MOD_GSK3_1	53	60	PF00069	0.547
MOD_GSK3_1	70	77	PF00069	0.538
MOD_N-GLC_1	21	26	PF02516	0.530
MOD_NEK2_1	1	6	PF00069	0.700
MOD_NEK2_1	104	109	PF00069	0.478
MOD_NEK2_1	111	116	PF00069	0.535
MOD_NEK2_1	157	162	PF00069	0.485
MOD_NEK2_1	17	22	PF00069	0.382
MOD_NEK2_1	209	214	PF00069	0.527
MOD_NEK2_1	38	43	PF00069	0.413
MOD_NEK2_1	57	62	PF00069	0.534
MOD_Plk_1	186	192	PF00069	0.525
MOD_Plk_1	73	79	PF00069	0.562
MOD_Plk_2-3	182	188	PF00069	0.729
MOD_Plk_4	157	163	PF00069	0.464
MOD_Plk_4	53	59	PF00069	0.500
MOD_Plk_4	76	82	PF00069	0.505
MOD_ProDKin_1	81	87	PF00069	0.605
TRG_DiLeu_BaLyEn_6	13	18	PF01217	0.586
TRG_ER_diArg_1	162	165	PF00400	0.465
TRG_ER_diArg_1	197	200	PF00400	0.521

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5S5	Leptomonas seymouri	39%	100%
A0A1X0P489	Trypanosomatidae	28%	100%
A0A3S7X0S9	Leishmania donovani	89%	100%
A4HFT6	Leishmania braziliensis	69%	100%
A4I2V3	Leishmania infantum	89%	100%
E9ADD9	Leishmania major	88%	100%