LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

F-box only protein 22

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
F-box only protein 22
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AZ45_LEIMU
TriTrypDb:
LmxM.27.1400
Length:
144

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 1, no: 8
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AZ45
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZ45

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 52 56 PF00656 0.428
CLV_NRD_NRD_1 136 138 PF00675 0.598
CLV_NRD_NRD_1 87 89 PF00675 0.454
CLV_PCSK_KEX2_1 136 138 PF00082 0.482
CLV_PCSK_KEX2_1 87 89 PF00082 0.385
CLV_PCSK_SKI1_1 124 128 PF00082 0.422
CLV_PCSK_SKI1_1 3 7 PF00082 0.494
CLV_PCSK_SKI1_1 54 58 PF00082 0.440
DEG_APCC_DBOX_1 123 131 PF00400 0.421
DOC_MAPK_MEF2A_6 120 127 PF00069 0.409
DOC_PIKK_1 84 92 PF02985 0.549
LIG_14-3-3_CanoR_1 3 8 PF00244 0.470
LIG_BIR_II_1 1 5 PF00653 0.506
LIG_eIF4E_1 112 118 PF01652 0.456
LIG_FHA_1 4 10 PF00498 0.448
LIG_FHA_2 8 14 PF00498 0.403
LIG_LIR_Apic_2 10 14 PF02991 0.413
LIG_LIR_Nem_3 55 61 PF02991 0.436
LIG_LIR_Nem_3 84 89 PF02991 0.435
LIG_NRBOX 4 10 PF00104 0.384
LIG_SH2_CRK 58 62 PF00017 0.447
LIG_SH2_CRK 86 90 PF00017 0.454
LIG_SH2_NCK_1 11 15 PF00017 0.432
LIG_SH2_NCK_1 112 116 PF00017 0.471
LIG_SH2_SRC 11 14 PF00017 0.423
LIG_SH2_SRC 73 76 PF00017 0.417
LIG_SH2_STAT5 73 76 PF00017 0.395
LIG_SUMO_SIM_par_1 5 10 PF11976 0.381
LIG_UBA3_1 64 68 PF00899 0.566
MOD_CK2_1 78 84 PF00069 0.508
MOD_GSK3_1 136 143 PF00069 0.737
MOD_GSK3_1 3 10 PF00069 0.463
MOD_N-GLC_1 49 54 PF02516 0.485
MOD_NEK2_1 57 62 PF00069 0.427
MOD_NEK2_1 78 83 PF00069 0.548
MOD_NEK2_1 92 97 PF00069 0.621
MOD_NEK2_2 38 43 PF00069 0.477
MOD_PIKK_1 78 84 PF00454 0.508
MOD_PKA_1 136 142 PF00069 0.492
MOD_PKA_2 136 142 PF00069 0.720
MOD_Plk_4 3 9 PF00069 0.449
TRG_ENDOCYTIC_2 112 115 PF00928 0.476
TRG_ENDOCYTIC_2 58 61 PF00928 0.442
TRG_ENDOCYTIC_2 86 89 PF00928 0.440
TRG_ER_diArg_1 86 88 PF00400 0.483
TRG_NES_CRM1_1 55 71 PF08389 0.477

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P5C5 Leptomonas seymouri 86% 100%
A0A1X0P4D7 Trypanosomatidae 77% 100%
A0A3Q8IGC5 Leishmania donovani 92% 100%
A0A422NFQ4 Trypanosoma rangeli 71% 100%
A4HFR7 Leishmania braziliensis 86% 99%
A4I2U2 Leishmania infantum 92% 100%
D0A608 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 69% 100%
E9ADC1 Leishmania major 92% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS