C3H1-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

KH domain containing protein, putative

Species:

Leishmania mexicana

UniProt:

E9AZ36_LEIMU

TriTrypDb:

LmxM.27.1300

Length:

529

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Show entries

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005737	cytoplasm	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Previous1Next

Expansion

Sequence features

E9AZ36

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZ36

Function

Could not find GO biological_process term for this entry.

Show entries

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	8
GO:0003723	RNA binding	4	8
GO:0003724	RNA helicase activity	3	1
GO:0003824	catalytic activity	1	1
GO:0004386	helicase activity	2	1
GO:0005488	binding	1	12
GO:0008186	ATP-dependent activity, acting on RNA	2	1
GO:0043167	ion binding	2	12
GO:0043169	cation binding	3	12
GO:0046872	metal ion binding	4	12

Previous1 2Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	157	159	PF00675	0.753
CLV_NRD_NRD_1	34	36	PF00675	0.546
CLV_NRD_NRD_1	416	418	PF00675	0.466
CLV_NRD_NRD_1	68	70	PF00675	0.833
CLV_PCSK_KEX2_1	156	158	PF00082	0.709
CLV_PCSK_KEX2_1	254	256	PF00082	0.608
CLV_PCSK_KEX2_1	351	353	PF00082	0.467
CLV_PCSK_KEX2_1	527	529	PF00082	0.806
CLV_PCSK_KEX2_1	68	70	PF00082	0.772
CLV_PCSK_PC1ET2_1	254	256	PF00082	0.608

Previous1 2 3 4 5…15Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I4C0	Leptomonas seymouri	80%	99%
A0A0S4JP69	Bodo saltans	45%	100%
A0A1X0P4C7	Trypanosomatidae	48%	100%
A0A3S5H7H8	Leishmania donovani	98%	100%
A0A422NFN8	Trypanosoma rangeli	49%	100%
A4HFQ7	Leishmania braziliensis	87%	100%
A4I2T3	Leishmania infantum	98%	100%
D0A5Z7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	100%
E9ADB1	Leishmania major	98%	100%
V5BGH6	Trypanosoma cruzi	49%	100%

Previous1Next