LeishMANIAdb
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Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Secreted protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AZ35_LEIMU
TriTrypDb:
LmxM.27.1295
Length:
131

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AZ35
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZ35

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_MEL_PAP_1 99 105 PF00089 0.753
CLV_NRD_NRD_1 46 48 PF00675 0.770
CLV_PCSK_KEX2_1 45 47 PF00082 0.775
DEG_APCC_DBOX_1 46 54 PF00400 0.750
DOC_USP7_MATH_1 78 82 PF00917 0.770
LIG_14-3-3_CanoR_1 102 110 PF00244 0.501
LIG_14-3-3_CanoR_1 120 125 PF00244 0.489
LIG_14-3-3_CanoR_1 45 51 PF00244 0.762
LIG_14-3-3_CanoR_1 7 14 PF00244 0.735
LIG_14-3-3_CanoR_1 88 95 PF00244 0.784
LIG_BIR_II_1 1 5 PF00653 0.799
LIG_BRCT_BRCA1_1 86 90 PF00533 0.790
LIG_deltaCOP1_diTrp_1 83 90 PF00928 0.780
MOD_CK1_1 119 125 PF00069 0.805
MOD_CK1_1 91 97 PF00069 0.782
MOD_CMANNOS 3 6 PF00535 0.782
MOD_GlcNHglycan 122 125 PF01048 0.798
MOD_GlcNHglycan 90 93 PF01048 0.790
MOD_GlcNHglycan 96 99 PF01048 0.653
MOD_GSK3_1 116 123 PF00069 0.809
MOD_GSK3_1 35 42 PF00069 0.777
MOD_GSK3_1 84 91 PF00069 0.778
MOD_GSK3_1 94 101 PF00069 0.587
MOD_PIKK_1 19 25 PF00454 0.531
MOD_PIKK_1 7 13 PF00454 0.740
MOD_PIKK_1 70 76 PF00454 0.799
MOD_PKA_1 46 52 PF00069 0.753
MOD_PKA_2 101 107 PF00069 0.749
MOD_PKA_2 119 125 PF00069 0.490
MOD_PKA_2 46 52 PF00069 0.753
MOD_PKB_1 5 13 PF00069 0.748
MOD_PKB_1 86 94 PF00069 0.787
TRG_ER_diArg_1 109 112 PF00400 0.765
TRG_ER_diArg_1 113 116 PF00400 0.720
TRG_ER_diArg_1 44 47 PF00400 0.775
TRG_ER_diArg_1 85 88 PF00400 0.776
TRG_Pf-PMV_PEXEL_1 7 11 PF00026 0.746

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS