LeishMANIAdb
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Putative histone H1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Download

Quick info

Protein:
Putative histone H1
Gene product:
histone H1, putative
Species:
Leishmania mexicana
UniProt:
E9AZ22_LEIMU
TriTrypDb:
LmxM.27.1190
Length:
99

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Cellular components
Term Name Level Count
GO:0000786 nucleosome 3 2
GO:0032991 protein-containing complex 1 2
GO:0032993 protein-DNA complex 2 2
GO:0044815 DNA packaging complex 2 2

Expansion

Sequence features

E9AZ22
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZ22

Function

Biological processes
Term Name Level Count
GO:0006325 chromatin organization 4 2
GO:0006334 nucleosome assembly 7 2
GO:0006338 chromatin remodeling 5 2
GO:0009987 cellular process 1 2
GO:0016043 cellular component organization 3 2
GO:0022607 cellular component assembly 4 2
GO:0034728 nucleosome organization 6 2
GO:0043933 protein-containing complex organization 4 2
GO:0065003 protein-containing complex assembly 5 2
GO:0065004 protein-DNA complex assembly 6 2
GO:0071824 protein-DNA complex subunit organization 5 2
GO:0071840 cellular component organization or biogenesis 2 2
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 2
GO:0003677 DNA binding 4 2
GO:0005198 structural molecule activity 1 2
GO:0005488 binding 1 2
GO:0030527 structural constituent of chromatin 2 2
GO:0097159 organic cyclic compound binding 2 2
GO:1901363 heterocyclic compound binding 2 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 45 47 PF00082 0.846
CLV_PCSK_KEX2_1 58 60 PF00082 0.630
CLV_PCSK_PC1ET2_1 45 47 PF00082 0.846
CLV_PCSK_PC1ET2_1 58 60 PF00082 0.630
CLV_PCSK_SKI1_1 42 46 PF00082 0.839
CLV_PCSK_SKI1_1 55 59 PF00082 0.626
CLV_PCSK_SKI1_1 68 72 PF00082 0.608
CLV_PCSK_SKI1_1 76 80 PF00082 0.692
CLV_PCSK_SKI1_1 84 88 PF00082 0.540
CLV_PCSK_SKI1_1 92 96 PF00082 0.542
DOC_USP7_MATH_1 94 98 PF00917 0.828
DOC_USP7_UBL2_3 27 31 PF12436 0.818
DOC_USP7_UBL2_3 32 36 PF12436 0.729
DOC_USP7_UBL2_3 37 41 PF12436 0.649
DOC_USP7_UBL2_3 45 49 PF12436 0.531
DOC_USP7_UBL2_3 50 54 PF12436 0.539
DOC_USP7_UBL2_3 58 62 PF12436 0.622
DOC_USP7_UBL2_3 63 67 PF12436 0.533
DOC_USP7_UBL2_3 68 72 PF12436 0.520
DOC_USP7_UBL2_3 75 79 PF12436 0.535
DOC_USP7_UBL2_3 80 84 PF12436 0.530
DOC_USP7_UBL2_3 87 91 PF12436 0.484
DOC_USP7_UBL2_3 92 96 PF12436 0.525
DOC_WW_Pin1_4 13 18 PF00397 0.808
DOC_WW_Pin1_4 21 26 PF00397 0.691
LIG_BIR_II_1 1 5 PF00653 0.786
LIG_SH3_4 76 83 PF00018 0.828
LIG_SH3_4 84 91 PF00018 0.677
MOD_CDC14_SPxK_1 16 19 PF00782 0.819
MOD_CDC14_SPxK_1 24 27 PF00782 0.692
MOD_CDK_SPK_2 21 26 PF00069 0.831
MOD_CDK_SPxK_1 13 19 PF00069 0.813
MOD_CDK_SPxK_1 21 27 PF00069 0.692
MOD_CK1_1 2 8 PF00069 0.770
MOD_CK1_1 20 26 PF00069 0.513
MOD_GlcNHglycan 10 13 PF01048 0.677
MOD_GlcNHglycan 4 7 PF01048 0.765
MOD_GSK3_1 17 24 PF00069 0.667
MOD_GSK3_1 8 15 PF00069 0.786
MOD_GSK3_1 86 93 PF00069 0.817
MOD_ProDKin_1 13 19 PF00069 0.813
MOD_ProDKin_1 21 27 PF00069 0.692
TRG_ER_diLys_1 95 99 PF00400 0.843
TRG_NLS_Bipartite_1 79 99 PF00514 0.826
TRG_NLS_MonoExtC_3 94 99 PF00514 0.836
TRG_NLS_MonoExtN_4 92 99 PF00514 0.832

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS