Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Retinoic acid induced 16-like protein, putative

Species:

Leishmania mexicana

UniProt:

E9AZ19_LEIMU

TriTrypDb:

LmxM.27.1160

Length:

1006

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AZ19

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZ19

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	191	195	PF00656	0.548
CLV_C14_Caspase3-7	853	857	PF00656	0.487
CLV_C14_Caspase3-7	942	946	PF00656	0.648
CLV_NRD_NRD_1	312	314	PF00675	0.501
CLV_NRD_NRD_1	423	425	PF00675	0.501
CLV_NRD_NRD_1	49	51	PF00675	0.564
CLV_NRD_NRD_1	568	570	PF00675	0.518
CLV_NRD_NRD_1	694	696	PF00675	0.647
CLV_NRD_NRD_1	878	880	PF00675	0.636
CLV_PCSK_KEX2_1	397	399	PF00082	0.359
CLV_PCSK_KEX2_1	423	425	PF00082	0.417
CLV_PCSK_KEX2_1	49	51	PF00082	0.564
CLV_PCSK_KEX2_1	694	696	PF00082	0.414
CLV_PCSK_KEX2_1	783	785	PF00082	0.464
CLV_PCSK_KEX2_1	858	860	PF00082	0.487
CLV_PCSK_PC1ET2_1	397	399	PF00082	0.359
CLV_PCSK_PC1ET2_1	783	785	PF00082	0.464
CLV_PCSK_PC1ET2_1	858	860	PF00082	0.487
CLV_PCSK_SKI1_1	113	117	PF00082	0.554
CLV_PCSK_SKI1_1	205	209	PF00082	0.443
CLV_PCSK_SKI1_1	398	402	PF00082	0.478
CLV_PCSK_SKI1_1	428	432	PF00082	0.390
CLV_PCSK_SKI1_1	49	53	PF00082	0.478
CLV_PCSK_SKI1_1	561	565	PF00082	0.355
CLV_PCSK_SKI1_1	680	684	PF00082	0.509
CLV_PCSK_SKI1_1	870	874	PF00082	0.500
CLV_PCSK_SKI1_1	879	883	PF00082	0.624
DEG_APCC_DBOX_1	427	435	PF00400	0.407
DEG_APCC_DBOX_1	463	471	PF00400	0.363
DEG_SPOP_SBC_1	329	333	PF00917	0.727
DOC_CDC14_PxL_1	379	387	PF14671	0.375
DOC_CDC14_PxL_1	627	635	PF14671	0.403
DOC_CYCLIN_RxL_1	202	211	PF00134	0.472
DOC_CYCLIN_RxL_1	505	516	PF00134	0.415
DOC_CYCLIN_RxL_1	556	567	PF00134	0.366
DOC_MAPK_gen_1	397	404	PF00069	0.278
DOC_MAPK_gen_1	759	769	PF00069	0.555
DOC_MAPK_JIP1_4	300	306	PF00069	0.501
DOC_MAPK_MEF2A_6	300	308	PF00069	0.493
DOC_MAPK_MEF2A_6	397	404	PF00069	0.338
DOC_MAPK_MEF2A_6	56	65	PF00069	0.338
DOC_MAPK_MEF2A_6	905	913	PF00069	0.503
DOC_MAPK_RevD_3	846	859	PF00069	0.476
DOC_PP1_RVXF_1	554	560	PF00149	0.519
DOC_PP2B_LxvP_1	198	201	PF13499	0.538
DOC_PP2B_LxvP_1	304	307	PF13499	0.494
DOC_USP7_MATH_1	155	159	PF00917	0.714
DOC_USP7_MATH_1	17	21	PF00917	0.657
DOC_USP7_MATH_1	180	184	PF00917	0.761
DOC_USP7_MATH_1	23	27	PF00917	0.632
DOC_USP7_MATH_1	336	340	PF00917	0.660
DOC_USP7_MATH_1	433	437	PF00917	0.499
DOC_USP7_MATH_1	438	442	PF00917	0.452
DOC_USP7_MATH_1	612	616	PF00917	0.665
DOC_USP7_MATH_1	620	624	PF00917	0.459
DOC_USP7_MATH_1	785	789	PF00917	0.642
DOC_USP7_MATH_1	896	900	PF00917	0.716
DOC_USP7_MATH_1	936	940	PF00917	0.767
DOC_WW_Pin1_4	144	149	PF00397	0.681
DOC_WW_Pin1_4	176	181	PF00397	0.714
DOC_WW_Pin1_4	334	339	PF00397	0.735
DOC_WW_Pin1_4	38	43	PF00397	0.601
DOC_WW_Pin1_4	525	530	PF00397	0.499
DOC_WW_Pin1_4	54	59	PF00397	0.603
DOC_WW_Pin1_4	739	744	PF00397	0.405
DOC_WW_Pin1_4	808	813	PF00397	0.454
DOC_WW_Pin1_4	824	829	PF00397	0.373
DOC_WW_Pin1_4	882	887	PF00397	0.686
DOC_WW_Pin1_4	932	937	PF00397	0.721
LIG_14-3-3_CanoR_1	328	338	PF00244	0.687
LIG_14-3-3_CanoR_1	428	437	PF00244	0.412
LIG_14-3-3_CanoR_1	464	468	PF00244	0.388
LIG_14-3-3_CanoR_1	491	497	PF00244	0.369
LIG_14-3-3_CanoR_1	56	62	PF00244	0.367
LIG_14-3-3_CanoR_1	656	664	PF00244	0.462
LIG_14-3-3_CanoR_1	777	785	PF00244	0.594
LIG_14-3-3_CanoR_1	849	855	PF00244	0.411
LIG_14-3-3_CanoR_1	879	887	PF00244	0.716
LIG_14-3-3_CanoR_1	88	92	PF00244	0.550
LIG_Actin_WH2_2	312	330	PF00022	0.493
LIG_Actin_WH2_2	667	682	PF00022	0.492
LIG_AP2alpha_2	442	444	PF02296	0.508
LIG_APCC_ABBA_1	966	971	PF00400	0.281
LIG_BIR_II_1	1	5	PF00653	0.679
LIG_BRCT_BRCA1_1	126	130	PF00533	0.637
LIG_BRCT_BRCA1_1	909	913	PF00533	0.545
LIG_Clathr_ClatBox_1	760	764	PF01394	0.416
LIG_deltaCOP1_diTrp_1	67	76	PF00928	0.398
LIG_EH1_1	828	836	PF00400	0.517
LIG_eIF4E_1	829	835	PF01652	0.523
LIG_FAT_LD_1	404	412	PF03623	0.326
LIG_FHA_1	322	328	PF00498	0.567
LIG_FHA_1	339	345	PF00498	0.590
LIG_FHA_1	364	370	PF00498	0.460
LIG_FHA_1	38	44	PF00498	0.613
LIG_FHA_1	46	52	PF00498	0.599
LIG_FHA_1	463	469	PF00498	0.398
LIG_FHA_1	479	485	PF00498	0.401
LIG_FHA_1	504	510	PF00498	0.510
LIG_FHA_1	596	602	PF00498	0.642
LIG_FHA_1	624	630	PF00498	0.468
LIG_FHA_1	661	667	PF00498	0.390
LIG_FHA_1	834	840	PF00498	0.271
LIG_FHA_1	882	888	PF00498	0.709
LIG_FHA_2	372	378	PF00498	0.454
LIG_FHA_2	667	673	PF00498	0.477
LIG_FHA_2	82	88	PF00498	0.571
LIG_FHA_2	851	857	PF00498	0.426
LIG_GBD_Chelix_1	540	548	PF00786	0.481
LIG_LIR_Apic_2	626	631	PF02991	0.504
LIG_LIR_Gen_1	366	376	PF02991	0.384
LIG_LIR_Gen_1	399	409	PF02991	0.257
LIG_LIR_Gen_1	67	76	PF02991	0.399
LIG_LIR_LC3C_4	836	840	PF02991	0.480
LIG_LIR_Nem_3	366	371	PF02991	0.389
LIG_LIR_Nem_3	399	404	PF02991	0.257
LIG_LIR_Nem_3	622	628	PF02991	0.390
LIG_LIR_Nem_3	67	72	PF02991	0.375
LIG_LIR_Nem_3	74	79	PF02991	0.391
LIG_NRBOX	105	111	PF00104	0.488
LIG_NRBOX	270	276	PF00104	0.469
LIG_NRBOX	399	405	PF00104	0.391
LIG_NRBOX	756	762	PF00104	0.426
LIG_NRBOX	850	856	PF00104	0.530
LIG_PROFILIN_1	148	154	PF00235	0.496
LIG_Rb_pABgroove_1	909	917	PF01858	0.533
LIG_SH2_CRK	204	208	PF00017	0.469
LIG_SH2_CRK	915	919	PF00017	0.525
LIG_SH2_CRK	983	987	PF00017	0.406
LIG_SH2_PTP2	628	631	PF00017	0.401
LIG_SH2_SRC	972	975	PF00017	0.456
LIG_SH2_SRC	976	979	PF00017	0.418
LIG_SH2_STAP1	582	586	PF00017	0.578
LIG_SH2_STAP1	915	919	PF00017	0.436
LIG_SH2_STAP1	969	973	PF00017	0.499
LIG_SH2_STAT3	254	257	PF00017	0.486
LIG_SH2_STAT5	410	413	PF00017	0.438
LIG_SH2_STAT5	485	488	PF00017	0.410
LIG_SH2_STAT5	628	631	PF00017	0.401
LIG_SH2_STAT5	75	78	PF00017	0.384
LIG_SH2_STAT5	829	832	PF00017	0.531
LIG_SH2_STAT5	972	975	PF00017	0.505
LIG_SH2_STAT5	976	979	PF00017	0.514
LIG_SH2_STAT5	983	986	PF00017	0.552
LIG_SH3_1	145	151	PF00018	0.508
LIG_SH3_3	143	149	PF00018	0.678
LIG_SH3_3	211	217	PF00018	0.648
LIG_SH3_3	39	45	PF00018	0.517
LIG_SH3_3	583	589	PF00018	0.582
LIG_SH3_3	614	620	PF00018	0.611
LIG_SH3_3	906	912	PF00018	0.579
LIG_SUMO_SIM_anti_2	60	67	PF11976	0.407
LIG_SUMO_SIM_anti_2	663	669	PF11976	0.492
LIG_SUMO_SIM_anti_2	841	847	PF11976	0.498
LIG_SUMO_SIM_par_1	60	67	PF11976	0.449
LIG_SUMO_SIM_par_1	663	669	PF11976	0.451
LIG_SUMO_SIM_par_1	905	910	PF11976	0.622
LIG_TRAF2_1	416	419	PF00917	0.519
LIG_TYR_ITIM	981	986	PF00017	0.415
LIG_UBA3_1	248	256	PF00899	0.397
LIG_UBA3_1	308	314	PF00899	0.429
LIG_UBA3_1	467	472	PF00899	0.402
LIG_UBA3_1	509	515	PF00899	0.523
LIG_UBA3_1	778	783	PF00899	0.644
LIG_UBA3_1	91	100	PF00899	0.577
LIG_UBA3_1	990	994	PF00899	0.545
LIG_WRC_WIRS_1	621	626	PF05994	0.432
LIG_WW_1	201	204	PF00397	0.390
MOD_CDC14_SPxK_1	885	888	PF00782	0.707
MOD_CDK_SPK_2	739	744	PF00069	0.405
MOD_CDK_SPxK_1	882	888	PF00069	0.691
MOD_CDK_SPxxK_3	882	889	PF00069	0.696
MOD_CK1_1	133	139	PF00069	0.568
MOD_CK1_1	183	189	PF00069	0.684
MOD_CK1_1	337	343	PF00069	0.580
MOD_CK1_1	4	10	PF00069	0.476
MOD_CK1_1	528	534	PF00069	0.441
MOD_CK1_1	57	63	PF00069	0.480
MOD_CK1_1	623	629	PF00069	0.423
MOD_CK1_1	788	794	PF00069	0.598
MOD_CK1_1	827	833	PF00069	0.423
MOD_CK1_1	894	900	PF00069	0.660
MOD_CK1_1	935	941	PF00069	0.677
MOD_CK1_1	943	949	PF00069	0.480
MOD_CK2_1	131	137	PF00069	0.579
MOD_CK2_1	371	377	PF00069	0.397
MOD_CK2_1	413	419	PF00069	0.508
MOD_CK2_1	612	618	PF00069	0.610
MOD_CK2_1	666	672	PF00069	0.478
MOD_CK2_1	81	87	PF00069	0.567
MOD_DYRK1A_RPxSP_1	932	936	PF00069	0.479
MOD_GlcNHglycan	137	140	PF01048	0.739
MOD_GlcNHglycan	156	160	PF01048	0.780
MOD_GlcNHglycan	180	183	PF01048	0.644
MOD_GlcNHglycan	283	287	PF01048	0.571
MOD_GlcNHglycan	3	6	PF01048	0.481
MOD_GlcNHglycan	301	304	PF01048	0.523
MOD_GlcNHglycan	334	337	PF01048	0.753
MOD_GlcNHglycan	34	37	PF01048	0.707
MOD_GlcNHglycan	414	418	PF01048	0.491
MOD_GlcNHglycan	431	434	PF01048	0.520
MOD_GlcNHglycan	534	537	PF01048	0.390
MOD_GlcNHglycan	550	553	PF01048	0.419
MOD_GlcNHglycan	571	574	PF01048	0.516
MOD_GlcNHglycan	593	596	PF01048	0.652
MOD_GlcNHglycan	657	660	PF01048	0.531
MOD_GlcNHglycan	706	709	PF01048	0.626
MOD_GlcNHglycan	736	739	PF01048	0.488
MOD_GlcNHglycan	779	782	PF01048	0.601
MOD_GlcNHglycan	891	894	PF01048	0.538
MOD_GlcNHglycan	896	899	PF01048	0.590
MOD_GlcNHglycan	947	951	PF01048	0.609
MOD_GlcNHglycan	995	998	PF01048	0.520
MOD_GSK3_1	131	138	PF00069	0.597
MOD_GSK3_1	17	24	PF00069	0.787
MOD_GSK3_1	171	178	PF00069	0.771
MOD_GSK3_1	180	187	PF00069	0.679
MOD_GSK3_1	28	35	PF00069	0.725
MOD_GSK3_1	282	289	PF00069	0.454
MOD_GSK3_1	327	334	PF00069	0.653
MOD_GSK3_1	409	416	PF00069	0.502
MOD_GSK3_1	429	436	PF00069	0.435
MOD_GSK3_1	450	457	PF00069	0.341
MOD_GSK3_1	462	469	PF00069	0.413
MOD_GSK3_1	495	502	PF00069	0.445
MOD_GSK3_1	528	535	PF00069	0.436
MOD_GSK3_1	591	598	PF00069	0.622
MOD_GSK3_1	619	626	PF00069	0.586
MOD_GSK3_1	651	658	PF00069	0.630
MOD_GSK3_1	730	737	PF00069	0.628
MOD_GSK3_1	787	794	PF00069	0.664
MOD_GSK3_1	808	815	PF00069	0.523
MOD_GSK3_1	823	830	PF00069	0.324
MOD_GSK3_1	850	857	PF00069	0.480
MOD_GSK3_1	932	939	PF00069	0.688
MOD_N-GLC_1	889	894	PF02516	0.488
MOD_N-GLC_1	939	944	PF02516	0.665
MOD_NEK2_1	1	6	PF00069	0.502
MOD_NEK2_1	130	135	PF00069	0.643
MOD_NEK2_1	184	189	PF00069	0.692
MOD_NEK2_1	208	213	PF00069	0.540
MOD_NEK2_1	27	32	PF00069	0.676
MOD_NEK2_1	371	376	PF00069	0.393
MOD_NEK2_1	429	434	PF00069	0.515
MOD_NEK2_1	492	497	PF00069	0.450
MOD_NEK2_1	548	553	PF00069	0.417
MOD_NEK2_1	563	568	PF00069	0.362
MOD_NEK2_1	601	606	PF00069	0.635
MOD_NEK2_1	650	655	PF00069	0.611
MOD_NEK2_1	666	671	PF00069	0.264
MOD_NEK2_1	838	843	PF00069	0.377
MOD_NEK2_1	854	859	PF00069	0.441
MOD_NEK2_1	891	896	PF00069	0.608
MOD_NEK2_1	907	912	PF00069	0.523
MOD_NEK2_1	993	998	PF00069	0.440
MOD_NEK2_2	620	625	PF00069	0.496
MOD_PIKK_1	363	369	PF00454	0.467
MOD_PIKK_1	392	398	PF00454	0.608
MOD_PIKK_1	478	484	PF00454	0.458
MOD_PIKK_1	984	990	PF00454	0.554
MOD_PK_1	100	106	PF00069	0.418
MOD_PKA_1	313	319	PF00069	0.511
MOD_PKA_1	423	429	PF00069	0.436
MOD_PKA_1	569	575	PF00069	0.521
MOD_PKA_1	879	885	PF00069	0.581
MOD_PKA_2	163	169	PF00069	0.787
MOD_PKA_2	299	305	PF00069	0.445
MOD_PKA_2	327	333	PF00069	0.746
MOD_PKA_2	423	429	PF00069	0.436
MOD_PKA_2	463	469	PF00069	0.365
MOD_PKA_2	655	661	PF00069	0.483
MOD_PKA_2	87	93	PF00069	0.560
MOD_PKA_2	943	949	PF00069	0.583
MOD_PKB_1	775	783	PF00069	0.579
MOD_Plk_1	282	288	PF00069	0.624
MOD_Plk_1	644	650	PF00069	0.688
MOD_Plk_1	86	92	PF00069	0.552
MOD_Plk_2-3	686	692	PF00069	0.611
MOD_Plk_2-3	94	100	PF00069	0.520
MOD_Plk_4	100	106	PF00069	0.418
MOD_Plk_4	124	130	PF00069	0.718
MOD_Plk_4	166	172	PF00069	0.515
MOD_Plk_4	292	298	PF00069	0.437
MOD_Plk_4	355	361	PF00069	0.553
MOD_Plk_4	463	469	PF00069	0.433
MOD_Plk_4	492	498	PF00069	0.373
MOD_Plk_4	518	524	PF00069	0.384
MOD_Plk_4	57	63	PF00069	0.453
MOD_Plk_4	620	626	PF00069	0.386
MOD_Plk_4	645	651	PF00069	0.680
MOD_Plk_4	660	666	PF00069	0.324
MOD_Plk_4	830	836	PF00069	0.379
MOD_Plk_4	850	856	PF00069	0.407
MOD_Plk_4	87	93	PF00069	0.608
MOD_ProDKin_1	144	150	PF00069	0.678
MOD_ProDKin_1	176	182	PF00069	0.712
MOD_ProDKin_1	334	340	PF00069	0.726
MOD_ProDKin_1	38	44	PF00069	0.602
MOD_ProDKin_1	525	531	PF00069	0.504
MOD_ProDKin_1	54	60	PF00069	0.587
MOD_ProDKin_1	739	745	PF00069	0.403
MOD_ProDKin_1	808	814	PF00069	0.448
MOD_ProDKin_1	824	830	PF00069	0.375
MOD_ProDKin_1	882	888	PF00069	0.691
MOD_ProDKin_1	932	938	PF00069	0.722
MOD_SUMO_rev_2	640	646	PF00179	0.649
TRG_DiLeu_BaEn_1	645	650	PF01217	0.641
TRG_DiLeu_BaEn_1	87	92	PF01217	0.553
TRG_DiLeu_BaLyEn_6	270	275	PF01217	0.373
TRG_DiLeu_BaLyEn_6	304	309	PF01217	0.392
TRG_DiLeu_BaLyEn_6	47	52	PF01217	0.480
TRG_DiLeu_BaLyEn_6	505	510	PF01217	0.555
TRG_DiLeu_BaLyEn_6	521	526	PF01217	0.345
TRG_DiLeu_BaLyEn_6	756	761	PF01217	0.425
TRG_DiLeu_BaLyEn_6	914	919	PF01217	0.287
TRG_ENDOCYTIC_2	204	207	PF00928	0.380
TRG_ENDOCYTIC_2	582	585	PF00928	0.563
TRG_ENDOCYTIC_2	627	630	PF00928	0.375
TRG_ENDOCYTIC_2	915	918	PF00928	0.415
TRG_ENDOCYTIC_2	983	986	PF00928	0.408
TRG_ER_diArg_1	49	51	PF00400	0.564
TRG_ER_diArg_1	693	695	PF00400	0.409
TRG_ER_diArg_1	772	775	PF00400	0.510
TRG_NES_CRM1_1	94	107	PF08389	0.503
TRG_Pf-PMV_PEXEL_1	205	210	PF00026	0.465
TRG_Pf-PMV_PEXEL_1	273	277	PF00026	0.398
TRG_Pf-PMV_PEXEL_1	49	54	PF00026	0.635
TRG_Pf-PMV_PEXEL_1	759	764	PF00026	0.432

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6X3	Leptomonas seymouri	52%	92%
A0A1X0P440	Trypanosomatidae	31%	98%
A0A3S5H7H7	Leishmania donovani	90%	100%
A0A3S5IQJ7	Trypanosoma rangeli	29%	100%
A4HFP1	Leishmania braziliensis	74%	99%
A4I2R7	Leishmania infantum	89%	100%
E9AD94	Leishmania major	88%	99%
V5BHP8	Trypanosoma cruzi	30%	100%