Mitochondrial SSU ribosomal protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Mitochondrial SSU ribosomal protein, putative

Species:

Leishmania mexicana

UniProt:

E9AYW4_LEIMU

TriTrypDb:

LmxM.27.0630

Length:

890

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	2
GO:0005840	ribosome	5	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1

Expansion

Sequence features

E9AYW4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AYW4

PDB structure(s): 7ane_u

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	454	458	PF00656	0.511
CLV_C14_Caspase3-7	771	775	PF00656	0.312
CLV_C14_Caspase3-7	866	870	PF00656	0.524
CLV_NRD_NRD_1	247	249	PF00675	0.418
CLV_NRD_NRD_1	379	381	PF00675	0.398
CLV_NRD_NRD_1	545	547	PF00675	0.487
CLV_NRD_NRD_1	552	554	PF00675	0.434
CLV_NRD_NRD_1	601	603	PF00675	0.471
CLV_NRD_NRD_1	672	674	PF00675	0.434
CLV_NRD_NRD_1	747	749	PF00675	0.347
CLV_NRD_NRD_1	790	792	PF00675	0.374
CLV_NRD_NRD_1	808	810	PF00675	0.358
CLV_NRD_NRD_1	861	863	PF00675	0.533
CLV_PCSK_FUR_1	669	673	PF00082	0.472
CLV_PCSK_KEX2_1	247	249	PF00082	0.398
CLV_PCSK_KEX2_1	253	255	PF00082	0.370
CLV_PCSK_KEX2_1	290	292	PF00082	0.479
CLV_PCSK_KEX2_1	378	380	PF00082	0.350
CLV_PCSK_KEX2_1	528	530	PF00082	0.540
CLV_PCSK_KEX2_1	545	547	PF00082	0.410
CLV_PCSK_KEX2_1	601	603	PF00082	0.436
CLV_PCSK_KEX2_1	671	673	PF00082	0.426
CLV_PCSK_KEX2_1	702	704	PF00082	0.393
CLV_PCSK_KEX2_1	731	733	PF00082	0.374
CLV_PCSK_KEX2_1	747	749	PF00082	0.281
CLV_PCSK_KEX2_1	808	810	PF00082	0.472
CLV_PCSK_KEX2_1	842	844	PF00082	0.500
CLV_PCSK_PC1ET2_1	253	255	PF00082	0.407
CLV_PCSK_PC1ET2_1	290	292	PF00082	0.423
CLV_PCSK_PC1ET2_1	378	380	PF00082	0.350
CLV_PCSK_PC1ET2_1	528	530	PF00082	0.577
CLV_PCSK_PC1ET2_1	702	704	PF00082	0.393
CLV_PCSK_PC1ET2_1	731	733	PF00082	0.385
CLV_PCSK_PC1ET2_1	842	844	PF00082	0.473
CLV_PCSK_PC7_1	838	844	PF00082	0.446
CLV_PCSK_SKI1_1	16	20	PF00082	0.676
CLV_PCSK_SKI1_1	212	216	PF00082	0.396
CLV_PCSK_SKI1_1	254	258	PF00082	0.399
CLV_PCSK_SKI1_1	280	284	PF00082	0.383
CLV_PCSK_SKI1_1	291	295	PF00082	0.395
CLV_PCSK_SKI1_1	387	391	PF00082	0.449
CLV_PCSK_SKI1_1	398	402	PF00082	0.431
CLV_PCSK_SKI1_1	425	429	PF00082	0.594
CLV_PCSK_SKI1_1	446	450	PF00082	0.409
CLV_PCSK_SKI1_1	501	505	PF00082	0.401
CLV_PCSK_SKI1_1	515	519	PF00082	0.412
CLV_PCSK_SKI1_1	524	528	PF00082	0.517
CLV_PCSK_SKI1_1	562	566	PF00082	0.411
CLV_PCSK_SKI1_1	838	842	PF00082	0.400
CLV_PCSK_SKI1_1	843	847	PF00082	0.401
CLV_Separin_Metazoa	244	248	PF03568	0.429
DEG_APCC_DBOX_1	258	266	PF00400	0.368
DEG_COP1_1	361	369	PF00400	0.479
DEG_Nend_Nbox_1	1	3	PF02207	0.627
DEG_SCF_FBW7_1	318	324	PF00400	0.479
DOC_CKS1_1	318	323	PF01111	0.483
DOC_CKS1_1	846	851	PF01111	0.405
DOC_CYCLIN_RxL_1	384	392	PF00134	0.497
DOC_CYCLIN_RxL_1	497	506	PF00134	0.518
DOC_CYCLIN_RxL_1	524	534	PF00134	0.481
DOC_CYCLIN_RxL_1	838	848	PF00134	0.417
DOC_CYCLIN_yCln2_LP_2	504	510	PF00134	0.501
DOC_MAPK_gen_1	838	847	PF00069	0.419
DOC_MAPK_MEF2A_6	797	805	PF00069	0.543
DOC_PP1_RVXF_1	210	216	PF00149	0.369
DOC_PP1_RVXF_1	278	284	PF00149	0.382
DOC_PP4_FxxP_1	684	687	PF00568	0.423
DOC_PP4_FxxP_1	846	849	PF00568	0.379
DOC_USP7_MATH_1	105	109	PF00917	0.488
DOC_USP7_MATH_1	228	232	PF00917	0.551
DOC_USP7_MATH_1	402	406	PF00917	0.540
DOC_USP7_MATH_1	462	466	PF00917	0.571
DOC_USP7_MATH_1	474	478	PF00917	0.630
DOC_USP7_MATH_1	485	489	PF00917	0.476
DOC_USP7_MATH_1	580	584	PF00917	0.476
DOC_USP7_MATH_1	632	636	PF00917	0.624
DOC_USP7_MATH_2	344	350	PF00917	0.300
DOC_USP7_UBL2_3	249	253	PF12436	0.451
DOC_USP7_UBL2_3	524	528	PF12436	0.540
DOC_WW_Pin1_4	157	162	PF00397	0.462
DOC_WW_Pin1_4	231	236	PF00397	0.526
DOC_WW_Pin1_4	26	31	PF00397	0.678
DOC_WW_Pin1_4	296	301	PF00397	0.470
DOC_WW_Pin1_4	317	322	PF00397	0.517
DOC_WW_Pin1_4	371	376	PF00397	0.450
DOC_WW_Pin1_4	637	642	PF00397	0.436
DOC_WW_Pin1_4	845	850	PF00397	0.411
LIG_14-3-3_CanoR_1	267	274	PF00244	0.239
LIG_14-3-3_CanoR_1	562	568	PF00244	0.442
LIG_14-3-3_CanoR_1	654	658	PF00244	0.353
LIG_14-3-3_CanoR_1	719	724	PF00244	0.246
LIG_APCC_ABBA_1	144	149	PF00400	0.461
LIG_APCC_ABBAyCdc20_2	143	149	PF00400	0.459
LIG_BIR_III_2	155	159	PF00653	0.506
LIG_BIR_III_4	734	738	PF00653	0.435
LIG_BIR_III_4	869	873	PF00653	0.573
LIG_BRCT_BRCA1_1	206	210	PF00533	0.434
LIG_BRCT_BRCA1_1	464	468	PF00533	0.452
LIG_BRCT_BRCA1_2	206	212	PF00533	0.433
LIG_deltaCOP1_diTrp_1	276	283	PF00928	0.317
LIG_deltaCOP1_diTrp_1	491	496	PF00928	0.424
LIG_deltaCOP1_diTrp_1	705	709	PF00928	0.376
LIG_EH_1	737	741	PF12763	0.494
LIG_FHA_1	12	18	PF00498	0.684
LIG_FHA_1	204	210	PF00498	0.387
LIG_FHA_1	322	328	PF00498	0.361
LIG_FHA_1	440	446	PF00498	0.619
LIG_FHA_1	525	531	PF00498	0.644
LIG_FHA_1	55	61	PF00498	0.589
LIG_FHA_1	550	556	PF00498	0.474
LIG_FHA_1	571	577	PF00498	0.378
LIG_FHA_2	563	569	PF00498	0.448
LIG_FHA_2	846	852	PF00498	0.400
LIG_FHA_2	879	885	PF00498	0.600
LIG_LIR_Apic_2	682	687	PF02991	0.528
LIG_LIR_Apic_2	734	739	PF02991	0.517
LIG_LIR_Apic_2	844	849	PF02991	0.391
LIG_LIR_Gen_1	207	217	PF02991	0.500
LIG_LIR_Gen_1	368	377	PF02991	0.503
LIG_LIR_Gen_1	565	575	PF02991	0.411
LIG_LIR_Gen_1	62	72	PF02991	0.431
LIG_LIR_Gen_1	649	659	PF02991	0.488
LIG_LIR_Gen_1	694	704	PF02991	0.407
LIG_LIR_Gen_1	816	826	PF02991	0.442
LIG_LIR_Gen_1	851	861	PF02991	0.448
LIG_LIR_Nem_3	207	213	PF02991	0.406
LIG_LIR_Nem_3	269	274	PF02991	0.369
LIG_LIR_Nem_3	276	282	PF02991	0.331
LIG_LIR_Nem_3	368	373	PF02991	0.509
LIG_LIR_Nem_3	511	517	PF02991	0.536
LIG_LIR_Nem_3	565	570	PF02991	0.367
LIG_LIR_Nem_3	62	67	PF02991	0.445
LIG_LIR_Nem_3	649	655	PF02991	0.480
LIG_LIR_Nem_3	694	699	PF02991	0.410
LIG_LIR_Nem_3	798	803	PF02991	0.424
LIG_LIR_Nem_3	814	820	PF02991	0.402
LIG_LIR_Nem_3	832	837	PF02991	0.296
LIG_LIR_Nem_3	851	856	PF02991	0.419
LIG_NRBOX	147	153	PF00104	0.473
LIG_NRBOX	328	334	PF00104	0.426
LIG_NRBOX	385	391	PF00104	0.487
LIG_NRBOX	609	615	PF00104	0.483
LIG_NRBOX	782	788	PF00104	0.410
LIG_Pex14_1	279	283	PF04695	0.315
LIG_Pex14_1	706	710	PF04695	0.362
LIG_PTB_Apo_2	265	272	PF02174	0.354
LIG_PTB_Apo_2	695	702	PF02174	0.382
LIG_PTB_Apo_2	772	779	PF02174	0.265
LIG_PTB_Phospho_1	265	271	PF10480	0.358
LIG_PTB_Phospho_1	695	701	PF10480	0.383
LIG_PTB_Phospho_1	772	778	PF10480	0.271
LIG_Rb_LxCxE_1	583	599	PF01857	0.301
LIG_SH2_CRK	201	205	PF00017	0.463
LIG_SH2_CRK	514	518	PF00017	0.608
LIG_SH2_CRK	696	700	PF00017	0.408
LIG_SH2_CRK	736	740	PF00017	0.512
LIG_SH2_GRB2like	696	699	PF00017	0.432
LIG_SH2_NCK_1	567	571	PF00017	0.458
LIG_SH2_PTP2	652	655	PF00017	0.402
LIG_SH2_STAP1	535	539	PF00017	0.399
LIG_SH2_STAP1	769	773	PF00017	0.312
LIG_SH2_STAT3	657	660	PF00017	0.384
LIG_SH2_STAT3	704	707	PF00017	0.377
LIG_SH2_STAT3	769	772	PF00017	0.378
LIG_SH2_STAT5	271	274	PF00017	0.455
LIG_SH2_STAT5	330	333	PF00017	0.338
LIG_SH2_STAT5	644	647	PF00017	0.359
LIG_SH2_STAT5	652	655	PF00017	0.316
LIG_SH2_STAT5	657	660	PF00017	0.297
LIG_SH2_STAT5	873	876	PF00017	0.542
LIG_SH2_STAT5	93	96	PF00017	0.421
LIG_SH3_3	139	145	PF00018	0.426
LIG_SH3_3	155	161	PF00018	0.464
LIG_SH3_3	25	31	PF00018	0.719
LIG_SH3_3	315	321	PF00018	0.381
LIG_SH3_3	487	493	PF00018	0.504
LIG_SH3_3	597	603	PF00018	0.495
LIG_SH3_3	804	810	PF00018	0.434
LIG_SUMO_SIM_anti_2	187	194	PF11976	0.304
LIG_SUMO_SIM_anti_2	573	579	PF11976	0.487
LIG_SUMO_SIM_par_1	330	335	PF11976	0.395
LIG_TRAF2_1	119	122	PF00917	0.482
LIG_TRAF2_1	583	586	PF00917	0.442
LIG_TRAF2_1	98	101	PF00917	0.545
LIG_TYR_ITSM	563	570	PF00017	0.496
LIG_WW_3	29	33	PF00397	0.442
MOD_CDK_SPxK_1	26	32	PF00069	0.632
MOD_CDK_SPxxK_3	371	378	PF00069	0.445
MOD_CK1_1	231	237	PF00069	0.591
MOD_CK1_1	296	302	PF00069	0.532
MOD_CK1_1	451	457	PF00069	0.463
MOD_CK1_1	54	60	PF00069	0.559
MOD_CK1_1	62	68	PF00069	0.493
MOD_CK1_1	811	817	PF00069	0.412
MOD_CK2_1	116	122	PF00069	0.406
MOD_CK2_1	231	237	PF00069	0.466
MOD_CK2_1	332	338	PF00069	0.472
MOD_CK2_1	438	444	PF00069	0.425
MOD_CK2_1	562	568	PF00069	0.457
MOD_CK2_1	580	586	PF00069	0.351
MOD_CMANNOS	706	709	PF00535	0.369
MOD_GlcNHglycan	230	233	PF01048	0.483
MOD_GlcNHglycan	268	271	PF01048	0.306
MOD_GlcNHglycan	301	304	PF01048	0.522
MOD_GlcNHglycan	348	351	PF01048	0.334
MOD_GlcNHglycan	367	370	PF01048	0.490
MOD_GlcNHglycan	404	407	PF01048	0.523
MOD_GlcNHglycan	453	456	PF01048	0.537
MOD_GlcNHglycan	457	460	PF01048	0.467
MOD_GlcNHglycan	487	490	PF01048	0.549
MOD_GlcNHglycan	626	629	PF01048	0.579
MOD_GlcNHglycan	810	813	PF01048	0.405
MOD_GSK3_1	292	299	PF00069	0.461
MOD_GSK3_1	317	324	PF00069	0.547
MOD_GSK3_1	332	339	PF00069	0.392
MOD_GSK3_1	365	372	PF00069	0.510
MOD_GSK3_1	444	451	PF00069	0.444
MOD_GSK3_1	470	477	PF00069	0.415
MOD_GSK3_1	502	509	PF00069	0.435
MOD_GSK3_1	620	627	PF00069	0.533
MOD_GSK3_1	774	781	PF00069	0.375
MOD_GSK3_1	841	848	PF00069	0.419
MOD_GSK3_1	874	881	PF00069	0.560
MOD_LATS_1	127	133	PF00433	0.506
MOD_LATS_1	717	723	PF00433	0.348
MOD_N-GLC_1	204	209	PF02516	0.328
MOD_N-GLC_1	518	523	PF02516	0.521
MOD_N-GLC_1	562	567	PF02516	0.479
MOD_N-GLC_1	62	67	PF02516	0.623
MOD_N-GLC_1	719	724	PF02516	0.346
MOD_N-GLC_1	774	779	PF02516	0.362
MOD_NEK2_1	19	24	PF00069	0.694
MOD_NEK2_1	204	209	PF00069	0.452
MOD_NEK2_1	282	287	PF00069	0.436
MOD_NEK2_1	293	298	PF00069	0.470
MOD_NEK2_1	332	337	PF00069	0.401
MOD_NEK2_1	448	453	PF00069	0.423
MOD_NEK2_1	470	475	PF00069	0.535
MOD_NEK2_1	76	81	PF00069	0.468
MOD_NEK2_2	596	601	PF00069	0.332
MOD_PIKK_1	679	685	PF00454	0.545
MOD_PK_1	719	725	PF00069	0.475
MOD_PKA_1	808	814	PF00069	0.415
MOD_PKA_1	841	847	PF00069	0.416
MOD_PKA_2	266	272	PF00069	0.232
MOD_PKA_2	653	659	PF00069	0.354
MOD_PKA_2	808	814	PF00069	0.459
MOD_PKB_1	618	626	PF00069	0.505
MOD_Plk_1	105	111	PF00069	0.495
MOD_Plk_1	204	210	PF00069	0.383
MOD_Plk_1	562	568	PF00069	0.415
MOD_Plk_1	570	576	PF00069	0.376
MOD_Plk_1	62	68	PF00069	0.556
MOD_Plk_1	719	725	PF00069	0.343
MOD_Plk_1	774	780	PF00069	0.364
MOD_Plk_2-3	506	512	PF00069	0.428
MOD_Plk_4	105	111	PF00069	0.557
MOD_Plk_4	385	391	PF00069	0.291
MOD_Plk_4	444	450	PF00069	0.418
MOD_Plk_4	653	659	PF00069	0.352
MOD_Plk_4	813	819	PF00069	0.447
MOD_ProDKin_1	157	163	PF00069	0.454
MOD_ProDKin_1	231	237	PF00069	0.530
MOD_ProDKin_1	26	32	PF00069	0.677
MOD_ProDKin_1	296	302	PF00069	0.457
MOD_ProDKin_1	317	323	PF00069	0.507
MOD_ProDKin_1	371	377	PF00069	0.449
MOD_ProDKin_1	637	643	PF00069	0.423
MOD_ProDKin_1	845	851	PF00069	0.413
MOD_SUMO_rev_2	440	448	PF00179	0.427
MOD_SUMO_rev_2	728	733	PF00179	0.478
MOD_SUMO_rev_2	798	807	PF00179	0.429
MOD_SUMO_rev_2	822	830	PF00179	0.527
MOD_SUMO_rev_2	851	859	PF00179	0.449
TRG_DiLeu_BaEn_1	444	449	PF01217	0.395
TRG_DiLeu_BaEn_4	121	127	PF01217	0.473
TRG_DiLeu_BaLyEn_6	512	517	PF01217	0.461
TRG_ENDOCYTIC_2	201	204	PF00928	0.482
TRG_ENDOCYTIC_2	330	333	PF00928	0.373
TRG_ENDOCYTIC_2	514	517	PF00928	0.599
TRG_ENDOCYTIC_2	567	570	PF00928	0.423
TRG_ENDOCYTIC_2	652	655	PF00928	0.374
TRG_ENDOCYTIC_2	696	699	PF00928	0.400
TRG_ENDOCYTIC_2	710	713	PF00928	0.320
TRG_ENDOCYTIC_2	817	820	PF00928	0.430
TRG_ER_diArg_1	246	248	PF00400	0.411
TRG_ER_diArg_1	379	381	PF00400	0.398
TRG_ER_diArg_1	600	602	PF00400	0.479
TRG_ER_diArg_1	617	620	PF00400	0.484
TRG_ER_diArg_1	669	672	PF00400	0.435
TRG_ER_diArg_1	747	750	PF00400	0.356
TRG_ER_diArg_1	807	809	PF00400	0.483
TRG_NLS_MonoExtC_3	552	558	PF00514	0.449
TRG_NLS_MonoExtN_4	375	382	PF00514	0.394
TRG_NLS_MonoExtN_4	838	845	PF00514	0.426
TRG_Pf-PMV_PEXEL_1	501	506	PF00026	0.503
TRG_Pf-PMV_PEXEL_1	750	754	PF00026	0.420
TRG_Pf-PMV_PEXEL_1	95	100	PF00026	0.473

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I6Z6	Leptomonas seymouri	71%	99%
A0A0S4JV63	Bodo saltans	39%	100%
A0A1X0P3Z7	Trypanosomatidae	50%	100%
A0A3S7X0G6	Leishmania donovani	94%	100%
A0A422NMT7	Trypanosoma rangeli	50%	100%
A4HFI9	Leishmania braziliensis	83%	100%
D0A5R5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	100%
E9AD40	Leishmania major	94%	100%
E9AHD3	Leishmania infantum	93%	100%