Amastin_surface_glycoprotein_-_putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Amastin surface glycoprotein, putative

Species:

Leishmania mexicana

UniProt:

E9AYV5_LEIMU

TriTrypDb:

LmxM.27.0540

Length:

209

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	8
GO:0110165	cellular anatomical entity	1	8

Expansion

Sequence features

E9AYV5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AYV5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
DEG_Nend_UBRbox_3	1	3	PF02207	0.655
DEG_SCF_FBW7_2	26	32	PF00400	0.422
DEG_SPOP_SBC_1	48	52	PF00917	0.318
DOC_CKS1_1	26	31	PF01111	0.419
DOC_MAPK_MEF2A_6	142	149	PF00069	0.525
DOC_PP4_FxxP_1	31	34	PF00568	0.387
DOC_USP7_MATH_1	73	77	PF00917	0.337
DOC_USP7_MATH_1	90	94	PF00917	0.359
DOC_WW_Pin1_4	25	30	PF00397	0.364
LIG_APCC_ABBA_1	204	209	PF00400	0.491
LIG_APCC_ABBA_1	27	32	PF00400	0.455
LIG_BRCT_BRCA1_1	49	53	PF00533	0.419
LIG_deltaCOP1_diTrp_1	181	188	PF00928	0.396
LIG_FHA_1	118	124	PF00498	0.438
LIG_FHA_1	157	163	PF00498	0.349
LIG_FHA_1	38	44	PF00498	0.315
LIG_FHA_1	50	56	PF00498	0.422
LIG_FHA_1	7	13	PF00498	0.534
LIG_LIR_Apic_2	28	34	PF02991	0.455
LIG_LIR_Gen_1	131	141	PF02991	0.398
LIG_LIR_Gen_1	98	109	PF02991	0.346
LIG_LIR_Nem_3	131	136	PF02991	0.385
LIG_LIR_Nem_3	63	68	PF02991	0.458
LIG_LIR_Nem_3	98	104	PF02991	0.330
LIG_Pex14_1	182	186	PF04695	0.306
LIG_Pex14_1	81	85	PF04695	0.359
LIG_Pex14_2	133	137	PF04695	0.369
LIG_Pex14_2	27	31	PF04695	0.364
LIG_SH2_CRK	186	190	PF00017	0.227
LIG_SH2_SRC	167	170	PF00017	0.345
LIG_SH2_STAT5	100	103	PF00017	0.301
LIG_SH2_STAT5	148	151	PF00017	0.356
LIG_SH2_STAT5	167	170	PF00017	0.301
LIG_SH3_3	23	29	PF00018	0.438
LIG_SH3_3	66	72	PF00018	0.396
LIG_SUMO_SIM_anti_2	114	120	PF11976	0.306
LIG_SUMO_SIM_par_1	202	209	PF11976	0.490
LIG_TYR_ITIM	184	189	PF00017	0.209
MOD_CK1_1	202	208	PF00069	0.355
MOD_CK1_1	76	82	PF00069	0.318
MOD_CMANNOS	182	185	PF00535	0.534
MOD_GlcNHglycan	137	140	PF01048	0.310
MOD_GlcNHglycan	14	17	PF01048	0.206
MOD_GlcNHglycan	69	72	PF01048	0.656
MOD_GlcNHglycan	87	90	PF01048	0.397
MOD_GSK3_1	156	163	PF00069	0.416
MOD_GSK3_1	191	198	PF00069	0.355
MOD_GSK3_1	2	9	PF00069	0.662
MOD_GSK3_1	33	40	PF00069	0.326
MOD_GSK3_1	44	51	PF00069	0.379
MOD_GSK3_1	54	61	PF00069	0.406
MOD_GSK3_1	81	88	PF00069	0.344
MOD_N-GLC_1	44	49	PF02516	0.653
MOD_NEK2_1	12	17	PF00069	0.362
MOD_NEK2_1	128	133	PF00069	0.338
MOD_NEK2_1	135	140	PF00069	0.322
MOD_NEK2_1	160	165	PF00069	0.476
MOD_NEK2_1	191	196	PF00069	0.403
MOD_NEK2_1	199	204	PF00069	0.372
MOD_NEK2_1	44	49	PF00069	0.453
MOD_NEK2_1	67	72	PF00069	0.370
MOD_OFUCOSY	3	10	PF10250	0.391
MOD_PIKK_1	176	182	PF00454	0.358
MOD_Plk_1	44	50	PF00069	0.434
MOD_Plk_2-3	58	64	PF00069	0.384
MOD_Plk_4	128	134	PF00069	0.422
MOD_Plk_4	195	201	PF00069	0.441
MOD_Plk_4	202	208	PF00069	0.402
MOD_Plk_4	76	82	PF00069	0.366
MOD_ProDKin_1	25	31	PF00069	0.364
TRG_DiLeu_BaEn_1	63	68	PF01217	0.318
TRG_ENDOCYTIC_2	148	151	PF00928	0.356
TRG_ENDOCYTIC_2	186	189	PF00928	0.267

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6T4	Leptomonas seymouri	51%	100%
A0A1X0NW81	Trypanosomatidae	32%	100%
A0A3S7X0F7	Leishmania donovani	89%	100%
A4HFI0	Leishmania braziliensis	65%	100%
C9ZWE1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	93%
E9AD31	Leishmania major	88%	100%
E9AHC4	Leishmania infantum	89%	100%