Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AYR6_LEIMU

TriTrypDb:

LmxM.27.0140

Length:

243

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AYR6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AYR6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	100	102	PF00675	0.588
CLV_NRD_NRD_1	161	163	PF00675	0.619
CLV_PCSK_KEX2_1	133	135	PF00082	0.623
CLV_PCSK_KEX2_1	7	9	PF00082	0.481
CLV_PCSK_PC1ET2_1	133	135	PF00082	0.623
CLV_PCSK_PC1ET2_1	7	9	PF00082	0.481
CLV_PCSK_SKI1_1	114	118	PF00082	0.593
CLV_PCSK_SKI1_1	139	143	PF00082	0.513
CLV_PCSK_SKI1_1	17	21	PF00082	0.625
CLV_PCSK_SKI1_1	170	174	PF00082	0.672
CLV_PCSK_SKI1_1	208	212	PF00082	0.690
DEG_APCC_DBOX_1	138	146	PF00400	0.442
DEG_Nend_Nbox_1	1	3	PF02207	0.532
DEG_SCF_FBW7_1	103	110	PF00400	0.474
DOC_CKS1_1	104	109	PF01111	0.477
DOC_CKS1_1	173	178	PF01111	0.614
DOC_USP7_MATH_1	155	159	PF00917	0.698
DOC_USP7_MATH_1	48	52	PF00917	0.594
DOC_USP7_MATH_1	80	84	PF00917	0.570
DOC_WW_Pin1_4	103	108	PF00397	0.519
DOC_WW_Pin1_4	147	152	PF00397	0.621
DOC_WW_Pin1_4	172	177	PF00397	0.613
DOC_WW_Pin1_4	19	24	PF00397	0.529
DOC_WW_Pin1_4	38	43	PF00397	0.730
DOC_WW_Pin1_4	92	97	PF00397	0.501
LIG_14-3-3_CanoR_1	134	138	PF00244	0.656
LIG_14-3-3_CanoR_1	17	23	PF00244	0.565
LIG_14-3-3_CanoR_1	212	220	PF00244	0.600
LIG_BIR_III_4	140	144	PF00653	0.637
LIG_deltaCOP1_diTrp_1	185	191	PF00928	0.597
LIG_FHA_1	133	139	PF00498	0.603
LIG_FHA_2	1	7	PF00498	0.478
LIG_FHA_2	113	119	PF00498	0.590
LIG_FHA_2	180	186	PF00498	0.656
LIG_FHA_2	93	99	PF00498	0.489
LIG_LIR_Nem_3	110	116	PF02991	0.702
LIG_Pex14_1	187	191	PF04695	0.591
LIG_SH2_CRK	113	117	PF00017	0.654
LIG_SH2_STAT5	105	108	PF00017	0.633
LIG_SH2_STAT5	226	229	PF00017	0.563
LIG_SH2_STAT5	240	243	PF00017	0.546
LIG_SH3_2	178	183	PF14604	0.547
LIG_SH3_3	175	181	PF00018	0.564
LIG_WRC_WIRS_1	188	193	PF05994	0.641
MOD_CDK_SPK_2	172	177	PF00069	0.613
MOD_CDK_SPK_2	92	97	PF00069	0.494
MOD_CDK_SPxxK_3	92	99	PF00069	0.491
MOD_CK1_1	18	24	PF00069	0.564
MOD_CK1_1	33	39	PF00069	0.524
MOD_CK1_1	51	57	PF00069	0.609
MOD_CK2_1	179	185	PF00069	0.656
MOD_GlcNHglycan	23	26	PF01048	0.647
MOD_GlcNHglycan	50	53	PF01048	0.468
MOD_GlcNHglycan	78	81	PF01048	0.457
MOD_GSK3_1	103	110	PF00069	0.619
MOD_GSK3_1	15	22	PF00069	0.630
MOD_GSK3_1	187	194	PF00069	0.643
MOD_GSK3_1	204	211	PF00069	0.457
MOD_GSK3_1	26	33	PF00069	0.429
MOD_GSK3_1	76	83	PF00069	0.518
MOD_N-GLC_1	153	158	PF02516	0.571
MOD_NEK2_1	132	137	PF00069	0.701
MOD_NEK2_1	191	196	PF00069	0.634
MOD_PIKK_1	1	7	PF00454	0.520
MOD_PIKK_1	122	128	PF00454	0.543
MOD_PIKK_1	26	32	PF00454	0.476
MOD_PKA_1	133	139	PF00069	0.603
MOD_PKA_2	133	139	PF00069	0.580
MOD_PKA_2	204	210	PF00069	0.536
MOD_PKA_2	233	239	PF00069	0.536
MOD_PKA_2	80	86	PF00069	0.607
MOD_Plk_1	15	21	PF00069	0.622
MOD_Plk_1	73	79	PF00069	0.629
MOD_Plk_4	133	139	PF00069	0.760
MOD_Plk_4	141	147	PF00069	0.427
MOD_Plk_4	51	57	PF00069	0.578
MOD_ProDKin_1	103	109	PF00069	0.517
MOD_ProDKin_1	147	153	PF00069	0.623
MOD_ProDKin_1	172	178	PF00069	0.612
MOD_ProDKin_1	19	25	PF00069	0.527
MOD_ProDKin_1	38	44	PF00069	0.730
MOD_ProDKin_1	92	98	PF00069	0.499
TRG_ENDOCYTIC_2	113	116	PF00928	0.564

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJK2	Leptomonas seymouri	39%	100%
A0A3Q8ID42	Leishmania donovani	89%	100%
A4I362	Leishmania infantum	91%	100%
E9ACZ1	Leishmania major	88%	100%
E9AIS4	Leishmania braziliensis	68%	100%