Odv-ec43

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Odv-ec43

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AYP9_LEIMU

TriTrypDb:

LmxM.26.2680

Length:

377

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 6, no: 0
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AYP9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AYP9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	339	343	PF00656	0.464
CLV_NRD_NRD_1	202	204	PF00675	0.519
CLV_PCSK_SKI1_1	204	208	PF00082	0.566
DEG_ODPH_VHL_1	44	56	PF01847	0.547
DEG_SPOP_SBC_1	56	60	PF00917	0.540
DOC_CKS1_1	155	160	PF01111	0.417
DOC_MAPK_gen_1	203	211	PF00069	0.481
DOC_MAPK_MEF2A_6	203	211	PF00069	0.481
DOC_PP1_RVXF_1	206	212	PF00149	0.430
DOC_PP4_FxxP_1	67	70	PF00568	0.402
DOC_USP7_MATH_1	210	214	PF00917	0.537
DOC_USP7_MATH_1	252	256	PF00917	0.594
DOC_USP7_MATH_1	296	300	PF00917	0.519
DOC_WW_Pin1_4	154	159	PF00397	0.444
DOC_WW_Pin1_4	34	39	PF00397	0.589
LIG_14-3-3_CanoR_1	112	117	PF00244	0.519
LIG_14-3-3_CanoR_1	33	41	PF00244	0.460
LIG_14-3-3_CanoR_1	72	81	PF00244	0.486
LIG_APCC_ABBAyCdc20_2	277	283	PF00400	0.510
LIG_BRCT_BRCA1_1	217	221	PF00533	0.507
LIG_FHA_1	150	156	PF00498	0.492
LIG_FHA_1	157	163	PF00498	0.473
LIG_FHA_1	18	24	PF00498	0.533
LIG_FHA_1	215	221	PF00498	0.641
LIG_FHA_1	255	261	PF00498	0.660
LIG_FHA_1	35	41	PF00498	0.663
LIG_FHA_1	58	64	PF00498	0.593
LIG_FHA_1	74	80	PF00498	0.496
LIG_FHA_2	337	343	PF00498	0.463
LIG_FHA_2	365	371	PF00498	0.425
LIG_FHA_2	57	63	PF00498	0.532
LIG_GBD_Chelix_1	8	16	PF00786	0.517
LIG_LIR_Gen_1	299	307	PF02991	0.455
LIG_LIR_Nem_3	159	164	PF02991	0.473
LIG_LIR_Nem_3	299	303	PF02991	0.552
LIG_LIR_Nem_3	358	364	PF02991	0.465
LIG_LIR_Nem_3	370	376	PF02991	0.412
LIG_LIR_Nem_3	95	100	PF02991	0.508
LIG_LYPXL_yS_3	164	167	PF13949	0.515
LIG_PTB_Apo_2	325	332	PF02174	0.430
LIG_SH2_CRK	124	128	PF00017	0.494
LIG_SH2_CRK	183	187	PF00017	0.524
LIG_SH2_CRK	300	304	PF00017	0.577
LIG_SH2_SRC	26	29	PF00017	0.581
LIG_SH2_SRC	373	376	PF00017	0.448
LIG_SH2_STAP1	225	229	PF00017	0.586
LIG_SH2_STAP1	233	237	PF00017	0.459
LIG_SH2_STAP1	300	304	PF00017	0.450
LIG_SH2_STAT5	179	182	PF00017	0.441
LIG_SH2_STAT5	373	376	PF00017	0.448
LIG_SH2_STAT5	7	10	PF00017	0.712
LIG_SH3_3	264	270	PF00018	0.521
LIG_SUMO_SIM_anti_2	228	233	PF11976	0.569
LIG_SUMO_SIM_anti_2	62	67	PF11976	0.486
LIG_TYR_ITIM	162	167	PF00017	0.524
LIG_TYR_ITIM	298	303	PF00017	0.461
LIG_Vh1_VBS_1	116	134	PF01044	0.393
MOD_CK1_1	190	196	PF00069	0.556
MOD_CK1_1	255	261	PF00069	0.595
MOD_CK1_1	57	63	PF00069	0.520
MOD_CK2_1	56	62	PF00069	0.594
MOD_GlcNHglycan	127	130	PF01048	0.503
MOD_GlcNHglycan	222	225	PF01048	0.609
MOD_GlcNHglycan	248	251	PF01048	0.524
MOD_GlcNHglycan	345	348	PF01048	0.573
MOD_GlcNHglycan	83	86	PF01048	0.505
MOD_GSK3_1	10	17	PF00069	0.571
MOD_GSK3_1	156	163	PF00069	0.388
MOD_GSK3_1	210	217	PF00069	0.559
MOD_GSK3_1	28	35	PF00069	0.432
MOD_GSK3_1	314	321	PF00069	0.468
MOD_GSK3_1	341	348	PF00069	0.547
MOD_GSK3_1	351	358	PF00069	0.418
MOD_GSK3_1	48	55	PF00069	0.552
MOD_N-GLC_1	100	105	PF02516	0.462
MOD_N-GLC_1	246	251	PF02516	0.579
MOD_N-GLC_1	253	258	PF02516	0.565
MOD_N-GLC_1	354	359	PF02516	0.616
MOD_N-GLC_1	92	97	PF02516	0.472
MOD_N-GLC_2	143	145	PF02516	0.518
MOD_NEK2_1	100	105	PF00069	0.542
MOD_NEK2_1	11	16	PF00069	0.507
MOD_NEK2_1	125	130	PF00069	0.558
MOD_NEK2_1	220	225	PF00069	0.535
MOD_NEK2_1	246	251	PF00069	0.475
MOD_NEK2_1	311	316	PF00069	0.510
MOD_NEK2_1	341	346	PF00069	0.472
MOD_NEK2_1	363	368	PF00069	0.493
MOD_NEK2_1	54	59	PF00069	0.543
MOD_NEK2_2	284	289	PF00069	0.566
MOD_PIKK_1	110	116	PF00454	0.537
MOD_PKA_2	125	131	PF00069	0.498
MOD_PKA_2	215	221	PF00069	0.635
MOD_PKA_2	32	38	PF00069	0.560
MOD_Plk_1	341	347	PF00069	0.474
MOD_Plk_1	354	360	PF00069	0.512
MOD_Plk_1	92	98	PF00069	0.522
MOD_Plk_2-3	336	342	PF00069	0.461
MOD_Plk_4	112	118	PF00069	0.713
MOD_Plk_4	175	181	PF00069	0.438
MOD_Plk_4	210	216	PF00069	0.685
MOD_Plk_4	336	342	PF00069	0.500
MOD_Plk_4	92	98	PF00069	0.657
MOD_ProDKin_1	154	160	PF00069	0.447
MOD_ProDKin_1	34	40	PF00069	0.588
TRG_ENDOCYTIC_2	124	127	PF00928	0.685
TRG_ENDOCYTIC_2	164	167	PF00928	0.515
TRG_ENDOCYTIC_2	183	186	PF00928	0.530
TRG_ENDOCYTIC_2	300	303	PF00928	0.578
TRG_ENDOCYTIC_2	373	376	PF00928	0.448
TRG_ENDOCYTIC_2	97	100	PF00928	0.638
TRG_NES_CRM1_1	69	83	PF08389	0.457

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCM7	Leptomonas seymouri	42%	100%
A0A3Q8IHC1	Leishmania donovani	91%	100%
A4HFB2	Leishmania braziliensis	72%	100%
A4I2J4	Leishmania infantum	91%	100%
Q4Q8S3	Leishmania major	88%	100%