Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AYN9_LEIMU

TriTrypDb:

LmxM.26.2580

Length:

151

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AYN9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AYN9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	121	125	PF00656	0.451
CLV_NRD_NRD_1	131	133	PF00675	0.669
CLV_NRD_NRD_1	33	35	PF00675	0.584
CLV_NRD_NRD_1	96	98	PF00675	0.711
CLV_PCSK_KEX2_1	131	133	PF00082	0.650
CLV_PCSK_KEX2_1	149	151	PF00082	0.530
CLV_PCSK_KEX2_1	33	35	PF00082	0.584
CLV_PCSK_KEX2_1	70	72	PF00082	0.553
CLV_PCSK_PC1ET2_1	149	151	PF00082	0.758
CLV_PCSK_PC1ET2_1	70	72	PF00082	0.480
CLV_PCSK_PC7_1	145	151	PF00082	0.692
CLV_PCSK_SKI1_1	18	22	PF00082	0.601
CLV_PCSK_SKI1_1	34	38	PF00082	0.594
CLV_PCSK_SKI1_1	70	74	PF00082	0.525
DOC_PP2B_LxvP_1	19	22	PF13499	0.575
DOC_USP7_MATH_1	119	123	PF00917	0.729
DOC_USP7_UBL2_3	78	82	PF12436	0.643
DOC_WW_Pin1_4	57	62	PF00397	0.624
LIG_14-3-3_CanoR_1	25	30	PF00244	0.589
LIG_14-3-3_CanoR_1	45	54	PF00244	0.402
LIG_Actin_WH2_2	102	120	PF00022	0.608
LIG_BIR_II_1	1	5	PF00653	0.511
LIG_FHA_1	24	30	PF00498	0.643
LIG_FHA_1	49	55	PF00498	0.659
LIG_SH2_GRB2like	91	94	PF00017	0.675
LIG_SH2_STAP1	91	95	PF00017	0.646
LIG_SH3_3	113	119	PF00018	0.699
LIG_SUMO_SIM_par_1	25	31	PF11976	0.533
LIG_SUMO_SIM_par_1	51	58	PF11976	0.689
LIG_SUMO_SIM_par_1	60	66	PF11976	0.563
LIG_TRAF2_1	28	31	PF00917	0.536
LIG_UBA3_1	72	78	PF00899	0.588
LIG_WW_3	142	146	PF00397	0.487
MOD_CK1_1	122	128	PF00069	0.699
MOD_CK1_1	48	54	PF00069	0.697
MOD_CK2_1	25	31	PF00069	0.543
MOD_Cter_Amidation	146	149	PF01082	0.780
MOD_Cter_Amidation	31	34	PF01082	0.575
MOD_GlcNHglycan	124	127	PF01048	0.619
MOD_GlcNHglycan	98	101	PF01048	0.645
MOD_GSK3_1	118	125	PF00069	0.703
MOD_N-GLC_1	66	71	PF02516	0.570
MOD_PKA_2	117	123	PF00069	0.701
MOD_PKA_2	96	102	PF00069	0.722
MOD_Plk_1	48	54	PF00069	0.663
MOD_ProDKin_1	57	63	PF00069	0.623
MOD_SUMO_rev_2	49	59	PF00179	0.690
TRG_DiLeu_BaEn_1	49	54	PF01217	0.698
TRG_DiLeu_BaEn_4	30	36	PF01217	0.556
TRG_ER_diArg_1	131	134	PF00400	0.660
TRG_ER_diArg_1	33	35	PF00400	0.585
TRG_ER_diLys_1	148	151	PF00400	0.697
TRG_NLS_MonoExtC_3	138	143	PF00514	0.686

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDC7	Leptomonas seymouri	78%	100%
A0A0S4JH37	Bodo saltans	37%	100%
A0A1X0NEM8	Trypanosomatidae	53%	100%
A0A3R7R8R4	Trypanosoma rangeli	53%	100%
A0A3S7X093	Leishmania donovani	94%	100%
A4HFA2	Leishmania braziliensis	85%	100%
C9ZX03	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	97%
Q4Q8T3	Leishmania major	91%	100%