Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AYI9_LEIMU

TriTrypDb:

LmxM.26.2090

Length:

113

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AYI9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AYI9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	15	19	PF00656	0.520
CLV_C14_Caspase3-7	87	91	PF00656	0.532
CLV_NRD_NRD_1	99	101	PF00675	0.575
CLV_PCSK_KEX2_1	99	101	PF00082	0.580
DOC_CYCLIN_yCln2_LP_2	71	77	PF00134	0.715
DOC_MAPK_MEF2A_6	72	81	PF00069	0.569
DOC_PP2B_LxvP_1	71	74	PF13499	0.741
DOC_USP7_MATH_1	48	52	PF00917	0.630
DOC_WW_Pin1_4	34	39	PF00397	0.580
LIG_14-3-3_CanoR_1	12	17	PF00244	0.515
LIG_BIR_II_1	1	5	PF00653	0.502
LIG_FHA_2	47	53	PF00498	0.708
LIG_IRF3_LxIS_1	75	82	PF10401	0.501
LIG_LIR_Gen_1	25	33	PF02991	0.570
LIG_LIR_Gen_1	65	76	PF02991	0.575
LIG_LIR_Gen_1	91	101	PF02991	0.560
LIG_LIR_Nem_3	25	30	PF02991	0.685
LIG_LIR_Nem_3	65	71	PF02991	0.600
LIG_LIR_Nem_3	82	86	PF02991	0.368
LIG_LIR_Nem_3	91	97	PF02991	0.479
LIG_MYND_1	42	46	PF01753	0.655
LIG_Pex14_2	84	88	PF04695	0.633
LIG_SH2_CRK	27	31	PF00017	0.564
LIG_SH2_CRK	94	98	PF00017	0.566
LIG_SH2_NCK_1	94	98	PF00017	0.517
LIG_SH2_STAT5	27	30	PF00017	0.494
LIG_SH2_STAT5	83	86	PF00017	0.519
LIG_SH3_3	35	41	PF00018	0.622
LIG_SH3_3	70	76	PF00018	0.676
LIG_TYR_ITIM	81	86	PF00017	0.477
MOD_CDK_SPxK_1	34	40	PF00069	0.584
MOD_CK1_1	105	111	PF00069	0.603
MOD_CK1_1	2	8	PF00069	0.543
MOD_CK1_1	63	69	PF00069	0.642
MOD_CK1_1	82	88	PF00069	0.326
MOD_CK2_1	46	52	PF00069	0.717
MOD_CK2_1	63	69	PF00069	0.497
MOD_GlcNHglycan	1	4	PF01048	0.536
MOD_GlcNHglycan	62	65	PF01048	0.631
MOD_GlcNHglycan	90	93	PF01048	0.532
MOD_GSK3_1	12	19	PF00069	0.585
MOD_N-GLC_1	53	58	PF02516	0.662
MOD_NEK2_1	79	84	PF00069	0.533
MOD_PIKK_1	102	108	PF00454	0.607
MOD_PK_1	12	18	PF00069	0.516
MOD_PKA_2	88	94	PF00069	0.536
MOD_Plk_1	100	106	PF00069	0.590
MOD_Plk_4	12	18	PF00069	0.589
MOD_ProDKin_1	34	40	PF00069	0.584
TRG_ENDOCYTIC_2	27	30	PF00928	0.560
TRG_ENDOCYTIC_2	68	71	PF00928	0.596
TRG_ENDOCYTIC_2	83	86	PF00928	0.375
TRG_ENDOCYTIC_2	94	97	PF00928	0.478

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ICY6	Leishmania donovani	96%	100%
A4HF53	Leishmania braziliensis	69%	100%
A4I2D7	Leishmania infantum	96%	100%
Q4Q8Y3	Leishmania major	95%	100%