Anaphase-promoting complex subunit 10

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AYH9_LEIMU

TriTrypDb:

LmxM.26.1990

Length:

226

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AYH9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AYH9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	100	104	PF00656	0.604
CLV_C14_Caspase3-7	20	24	PF00656	0.727
CLV_NRD_NRD_1	13	15	PF00675	0.807
CLV_NRD_NRD_1	168	170	PF00675	0.711
CLV_PCSK_KEX2_1	13	15	PF00082	0.801
CLV_PCSK_KEX2_1	168	170	PF00082	0.711
CLV_PCSK_KEX2_1	67	69	PF00082	0.507
CLV_PCSK_PC1ET2_1	67	69	PF00082	0.507
CLV_PCSK_SKI1_1	146	150	PF00082	0.614
DOC_CKS1_1	96	101	PF01111	0.551
DOC_MAPK_gen_1	210	220	PF00069	0.750
DOC_MAPK_MEF2A_6	213	222	PF00069	0.742
DOC_PP1_RVXF_1	89	96	PF00149	0.661
DOC_PP4_FxxP_1	34	37	PF00568	0.397
DOC_SPAK_OSR1_1	94	98	PF12202	0.495
DOC_USP7_MATH_1	152	156	PF00917	0.809
DOC_USP7_MATH_1	17	21	PF00917	0.791
DOC_WW_Pin1_4	167	172	PF00397	0.774
DOC_WW_Pin1_4	95	100	PF00397	0.569
LIG_14-3-3_CanoR_1	210	220	PF00244	0.678
LIG_BRCT_BRCA1_1	215	219	PF00533	0.655
LIG_BRCT_BRCA1_1	220	224	PF00533	0.637
LIG_BRCT_BRCA1_1	51	55	PF00533	0.520
LIG_EH1_1	116	124	PF00400	0.328
LIG_FHA_1	213	219	PF00498	0.643
LIG_FHA_1	48	54	PF00498	0.534
LIG_FHA_2	98	104	PF00498	0.536
LIG_LIR_Apic_2	59	63	PF02991	0.570
LIG_LIR_Gen_1	125	135	PF02991	0.644
LIG_LIR_Gen_1	216	226	PF02991	0.662
LIG_LIR_Nem_3	125	131	PF02991	0.560
LIG_LIR_Nem_3	216	222	PF02991	0.665
LIG_OCRL_FandH_1	105	117	PF00620	0.548
LIG_PDZ_Class_2	221	226	PF00595	0.612
LIG_PTB_Apo_2	89	96	PF02174	0.576
LIG_REV1ctd_RIR_1	175	184	PF16727	0.666
LIG_SH2_STAP1	203	207	PF00017	0.707
LIG_SH2_STAT3	117	120	PF00017	0.333
LIG_SH2_STAT3	203	206	PF00017	0.786
LIG_SH3_2	144	149	PF14604	0.701
LIG_SH3_3	141	147	PF00018	0.725
MOD_CK1_1	4	10	PF00069	0.712
MOD_GlcNHglycan	124	127	PF01048	0.527
MOD_GlcNHglycan	154	157	PF01048	0.611
MOD_GlcNHglycan	215	218	PF01048	0.704
MOD_GSK3_1	122	129	PF00069	0.473
MOD_GSK3_1	163	170	PF00069	0.723
MOD_GSK3_1	208	215	PF00069	0.566
MOD_N-GLC_1	173	178	PF02516	0.676
MOD_NEK2_1	122	127	PF00069	0.621
MOD_NEK2_1	163	168	PF00069	0.698
MOD_NEK2_1	218	223	PF00069	0.629
MOD_NEK2_1	46	51	PF00069	0.511
MOD_NEK2_2	104	109	PF00069	0.595
MOD_PIKK_1	208	214	PF00454	0.472
MOD_PIKK_1	62	68	PF00454	0.571
MOD_PKA_2	142	148	PF00069	0.555
MOD_PKA_2	212	218	PF00069	0.679
MOD_Plk_1	173	179	PF00069	0.674
MOD_Plk_2-3	199	205	PF00069	0.490
MOD_Plk_4	173	179	PF00069	0.746
MOD_ProDKin_1	167	173	PF00069	0.773
MOD_ProDKin_1	95	101	PF00069	0.565
TRG_Pf-PMV_PEXEL_1	132	136	PF00026	0.675
TRG_Pf-PMV_PEXEL_1	39	43	PF00026	0.546

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIW3	Leptomonas seymouri	62%	100%
A0A3S7X011	Leishmania donovani	89%	100%
A4HF43	Leishmania braziliensis	72%	100%
A4I2C7	Leishmania infantum	89%	100%
Q4Q8Z3	Leishmania major	90%	100%
V5BJ41	Trypanosoma cruzi	41%	100%