Putative cytochrome c oxidase subunit V

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cytochrome c oxidase subunit V, putative

Species:

Leishmania mexicana

UniProt:

E9AYF0_LEIMU

TriTrypDb:

LmxM.26.1710

Length:

196

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005929	cilium	4	1
GO:0042995	cell projection	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0110165	cellular anatomical entity	1	1
GO:0120025	plasma membrane bounded cell projection	3	1

Expansion

Sequence features

E9AYF0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AYF0

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	5
GO:0016491	oxidoreductase activity	2	5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	187	191	PF00656	0.538
CLV_NRD_NRD_1	36	38	PF00675	0.500
CLV_NRD_NRD_1	62	64	PF00675	0.515
CLV_PCSK_KEX2_1	2	4	PF00082	0.487
CLV_PCSK_KEX2_1	62	64	PF00082	0.515
CLV_PCSK_PC1ET2_1	2	4	PF00082	0.487
CLV_PCSK_SKI1_1	143	147	PF00082	0.469
CLV_PCSK_SKI1_1	16	20	PF00082	0.513
CLV_PCSK_SKI1_1	76	80	PF00082	0.537
CLV_PCSK_SKI1_1	88	92	PF00082	0.503
DEG_APCC_KENBOX_2	68	72	PF00400	0.496
DEG_Nend_UBRbox_1	1	4	PF02207	0.487
DOC_CDC14_PxL_1	95	103	PF14671	0.483
DOC_CKS1_1	176	181	PF01111	0.505
DOC_CYCLIN_RxL_1	140	148	PF00134	0.465
DOC_MAPK_gen_1	69	79	PF00069	0.527
DOC_MAPK_MEF2A_6	104	112	PF00069	0.538
DOC_MAPK_MEF2A_6	72	79	PF00069	0.593
DOC_PP4_FxxP_1	120	123	PF00568	0.565
DOC_PP4_FxxP_1	176	179	PF00568	0.503
DOC_PP4_FxxP_1	4	7	PF00568	0.529
DOC_PP4_FxxP_1	78	81	PF00568	0.510
DOC_SPAK_OSR1_1	3	7	PF12202	0.593
DOC_USP7_MATH_1	10	14	PF00917	0.446
DOC_USP7_UBL2_3	189	193	PF12436	0.517
DOC_WW_Pin1_4	151	156	PF00397	0.501
DOC_WW_Pin1_4	175	180	PF00397	0.502
LIG_14-3-3_CanoR_1	156	162	PF00244	0.513
LIG_14-3-3_CanoR_1	44	53	PF00244	0.522
LIG_APCC_ABBA_1	131	136	PF00400	0.516
LIG_eIF4E_1	140	146	PF01652	0.575
LIG_FHA_1	176	182	PF00498	0.574
LIG_GBD_Chelix_1	137	145	PF00786	0.461
LIG_LIR_Apic_2	118	123	PF02991	0.503
LIG_LIR_Apic_2	173	179	PF02991	0.497
LIG_LIR_Gen_1	124	135	PF02991	0.566
LIG_LIR_Gen_1	29	39	PF02991	0.497
LIG_LIR_Gen_1	73	81	PF02991	0.535
LIG_LIR_Nem_3	124	130	PF02991	0.569
LIG_LIR_Nem_3	73	77	PF02991	0.559
LIG_LYPXL_yS_3	98	101	PF13949	0.491
LIG_Pex14_2	19	23	PF04695	0.484
LIG_Pex14_2	74	78	PF04695	0.527
LIG_REV1ctd_RIR_1	16	25	PF16727	0.489
LIG_SH2_CRK	127	131	PF00017	0.522
LIG_SH2_STAP1	127	131	PF00017	0.574
LIG_SH2_STAP1	32	36	PF00017	0.588
LIG_SH2_STAP1	49	53	PF00017	0.459
LIG_SH2_STAP1	93	97	PF00017	0.473
LIG_SH2_STAT5	140	143	PF00017	0.616
LIG_SH3_3	127	133	PF00018	0.572
LIG_SH3_3	74	80	PF00018	0.529
LIG_SH3_5	123	127	PF00018	0.506
LIG_UBA3_1	145	150	PF00899	0.483
MOD_CDK_SPK_2	151	156	PF00069	0.501
MOD_CK2_1	141	147	PF00069	0.483
MOD_CK2_1	157	163	PF00069	0.636
MOD_GSK3_1	10	17	PF00069	0.505
MOD_GSK3_1	141	148	PF00069	0.495
MOD_GSK3_1	157	164	PF00069	0.613
MOD_GSK3_1	27	34	PF00069	0.598
MOD_GSK3_1	44	51	PF00069	0.479
MOD_N-GLC_1	70	75	PF02516	0.505
MOD_NEK2_1	141	146	PF00069	0.511
MOD_NEK2_1	161	166	PF00069	0.428
MOD_NEK2_2	27	32	PF00069	0.528
MOD_PIKK_1	44	50	PF00454	0.517
MOD_Plk_1	70	76	PF00069	0.506
MOD_Plk_4	141	147	PF00069	0.467
MOD_Plk_4	157	163	PF00069	0.522
MOD_Plk_4	27	33	PF00069	0.488
MOD_Plk_4	70	76	PF00069	0.506
MOD_Plk_4	91	97	PF00069	0.536
MOD_ProDKin_1	151	157	PF00069	0.497
MOD_ProDKin_1	175	181	PF00069	0.503
MOD_SUMO_for_1	108	111	PF00179	0.542
MOD_SUMO_for_1	149	152	PF00179	0.504
MOD_SUMO_rev_2	66	74	PF00179	0.533
TRG_DiLeu_BaEn_2	69	75	PF01217	0.524
TRG_DiLeu_BaLyEn_6	85	90	PF01217	0.472
TRG_ENDOCYTIC_2	127	130	PF00928	0.565
TRG_ENDOCYTIC_2	32	35	PF00928	0.625
TRG_ENDOCYTIC_2	93	96	PF00928	0.497
TRG_ENDOCYTIC_2	98	101	PF00928	0.476
TRG_ER_diArg_1	61	63	PF00400	0.534
TRG_Pf-PMV_PEXEL_1	143	147	PF00026	0.528
TRG_Pf-PMV_PEXEL_1	62	66	PF00026	0.504

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7C4	Leptomonas seymouri	92%	100%
A0A1X0NHI2	Trypanosomatidae	89%	100%
A0A3Q8IDX4	Leishmania donovani	96%	100%
A0A3R7N5B2	Trypanosoma rangeli	87%	100%
A4HD57	Leishmania braziliensis	94%	100%
A4I2A3	Leishmania infantum	96%	100%
C9ZXD9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	86%	100%
Q4Q922	Leishmania major	97%	100%