EF-hand domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AYD8_LEIMU

TriTrypDb:

LmxM.26.1590

Length:

309

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AYD8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AYD8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	178	182	PF00656	0.498
CLV_C14_Caspase3-7	213	217	PF00656	0.414
CLV_NRD_NRD_1	47	49	PF00675	0.435
CLV_NRD_NRD_1	6	8	PF00675	0.463
CLV_NRD_NRD_1	88	90	PF00675	0.491
CLV_PCSK_FUR_1	45	49	PF00082	0.442
CLV_PCSK_KEX2_1	45	47	PF00082	0.448
CLV_PCSK_KEX2_1	6	8	PF00082	0.551
CLV_PCSK_KEX2_1	77	79	PF00082	0.526
CLV_PCSK_KEX2_1	88	90	PF00082	0.583
CLV_PCSK_PC1ET2_1	77	79	PF00082	0.526
CLV_PCSK_PC7_1	41	47	PF00082	0.452
CLV_PCSK_SKI1_1	77	81	PF00082	0.471
DEG_APCC_DBOX_1	16	24	PF00400	0.470
DEG_APCC_DBOX_1	45	53	PF00400	0.428
DEG_SCF_FBW7_2	63	68	PF00400	0.470
DOC_MAPK_gen_1	88	96	PF00069	0.443
DOC_PP2B_LxvP_1	285	288	PF13499	0.499
DOC_SPAK_OSR1_1	39	43	PF12202	0.468
DOC_USP7_MATH_1	170	174	PF00917	0.690
DOC_WW_Pin1_4	211	216	PF00397	0.379
DOC_WW_Pin1_4	61	66	PF00397	0.472
LIG_14-3-3_CanoR_1	106	113	PF00244	0.641
LIG_14-3-3_CanoR_1	17	21	PF00244	0.469
LIG_14-3-3_CanoR_1	51	60	PF00244	0.496
LIG_14-3-3_CanoR_1	88	97	PF00244	0.717
LIG_14-3-3_CterR_2	306	309	PF00244	0.475
LIG_BRCT_BRCA1_1	10	14	PF00533	0.467
LIG_Clathr_ClatBox_1	133	137	PF01394	0.418
LIG_Clathr_ClatBox_1	142	146	PF01394	0.448
LIG_FHA_1	91	97	PF00498	0.453
LIG_FHA_2	123	129	PF00498	0.400
LIG_FHA_2	211	217	PF00498	0.383
LIG_LIR_Gen_1	12	23	PF02991	0.541
LIG_LIR_Gen_1	54	65	PF02991	0.437
LIG_LIR_Nem_3	12	18	PF02991	0.547
LIG_LIR_Nem_3	54	60	PF02991	0.698
LIG_MLH1_MIPbox_1	11	15	PF16413	0.473
LIG_NRBOX	251	257	PF00104	0.384
LIG_REV1ctd_RIR_1	12	21	PF16727	0.474
LIG_SH2_CRK	226	230	PF00017	0.359
LIG_SH2_CRK	57	61	PF00017	0.432
LIG_SH2_GRB2like	226	229	PF00017	0.370
LIG_SH2_NCK_1	226	230	PF00017	0.359
LIG_SH2_SRC	226	229	PF00017	0.370
LIG_SH2_STAP1	226	230	PF00017	0.372
LIG_SH2_STAT5	123	126	PF00017	0.525
LIG_SH2_STAT5	75	78	PF00017	0.452
LIG_TRAF2_1	173	176	PF00917	0.491
LIG_UBA3_1	251	260	PF00899	0.397
MOD_CDK_SPK_2	61	66	PF00069	0.463
MOD_CK1_1	105	111	PF00069	0.403
MOD_CK1_1	156	162	PF00069	0.518
MOD_CK1_1	200	206	PF00069	0.465
MOD_CK2_1	122	128	PF00069	0.469
MOD_CK2_1	154	160	PF00069	0.497
MOD_CK2_1	170	176	PF00069	0.459
MOD_CK2_1	291	297	PF00069	0.491
MOD_Cter_Amidation	86	89	PF01082	0.455
MOD_GlcNHglycan	137	140	PF01048	0.527
MOD_GlcNHglycan	25	28	PF01048	0.487
MOD_GlcNHglycan	264	268	PF01048	0.489
MOD_GlcNHglycan	30	33	PF01048	0.589
MOD_GSK3_1	102	109	PF00069	0.413
MOD_GSK3_1	124	131	PF00069	0.400
MOD_GSK3_1	171	178	PF00069	0.757
MOD_GSK3_1	196	203	PF00069	0.487
MOD_GSK3_1	23	30	PF00069	0.474
MOD_GSK3_1	273	280	PF00069	0.542
MOD_GSK3_1	47	54	PF00069	0.588
MOD_N-GLC_1	147	152	PF02516	0.524
MOD_N-GLC_1	61	66	PF02516	0.463
MOD_NEK2_1	129	134	PF00069	0.395
MOD_NEK2_1	184	189	PF00069	0.467
MOD_NEK2_1	256	261	PF00069	0.512
MOD_PIKK_1	171	177	PF00454	0.495
MOD_PIKK_1	200	206	PF00454	0.443
MOD_PIKK_1	55	61	PF00454	0.425
MOD_PKA_1	47	53	PF00069	0.420
MOD_PKA_1	89	95	PF00069	0.443
MOD_PKA_2	105	111	PF00069	0.643
MOD_PKA_2	16	22	PF00069	0.487
MOD_PKA_2	47	53	PF00069	0.670
MOD_PKB_1	45	53	PF00069	0.428
MOD_Plk_1	196	202	PF00069	0.470
MOD_Plk_4	129	135	PF00069	0.413
MOD_Plk_4	247	253	PF00069	0.393
MOD_Plk_4	9	15	PF00069	0.463
MOD_ProDKin_1	211	217	PF00069	0.379
MOD_ProDKin_1	61	67	PF00069	0.473
TRG_DiLeu_BaLyEn_6	280	285	PF01217	0.507
TRG_ENDOCYTIC_2	226	229	PF00928	0.573
TRG_ENDOCYTIC_2	57	60	PF00928	0.432
TRG_ER_diArg_1	191	194	PF00400	0.465
TRG_ER_diArg_1	45	48	PF00400	0.447
TRG_Pf-PMV_PEXEL_1	51	55	PF00026	0.416

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3R7RC16	Trypanosoma rangeli	28%	100%