Axonemal_dynein_light_chain_-_putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

axonemal dynein light chain, putative

Species:

Leishmania mexicana

UniProt:

E9AY91_LEIMU

TriTrypDb:

LmxM.26.1120

Length:

463

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005930	axoneme	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9AY91

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AY91

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	1
GO:0005515	protein binding	2	1
GO:0045504	dynein heavy chain binding	3	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	243	247	PF00656	0.674
CLV_MEL_PAP_1	87	93	PF00089	0.675
CLV_NRD_NRD_1	287	289	PF00675	0.353
CLV_NRD_NRD_1	377	379	PF00675	0.335
CLV_NRD_NRD_1	402	404	PF00675	0.335
CLV_NRD_NRD_1	428	430	PF00675	0.389
CLV_PCSK_KEX2_1	287	289	PF00082	0.335
CLV_PCSK_KEX2_1	401	403	PF00082	0.335
CLV_PCSK_KEX2_1	419	421	PF00082	0.335
CLV_PCSK_KEX2_1	440	442	PF00082	0.404
CLV_PCSK_KEX2_1	451	453	PF00082	0.417
CLV_PCSK_PC1ET2_1	419	421	PF00082	0.335
CLV_PCSK_PC1ET2_1	440	442	PF00082	0.404
CLV_PCSK_PC1ET2_1	451	453	PF00082	0.417
CLV_PCSK_SKI1_1	277	281	PF00082	0.259
CLV_PCSK_SKI1_1	338	342	PF00082	0.335
CLV_PCSK_SKI1_1	347	351	PF00082	0.335
DEG_SCF_FBW7_1	256	261	PF00400	0.688
DOC_CYCLIN_RxL_1	344	353	PF00134	0.453
DOC_PP4_FxxP_1	39	42	PF00568	0.641
DOC_USP7_MATH_1	102	106	PF00917	0.674
DOC_USP7_MATH_1	111	115	PF00917	0.710
DOC_USP7_MATH_1	118	122	PF00917	0.549
DOC_USP7_MATH_1	196	200	PF00917	0.614
DOC_USP7_MATH_1	262	266	PF00917	0.653
DOC_USP7_MATH_1	275	279	PF00917	0.374
DOC_USP7_MATH_1	311	315	PF00917	0.313
DOC_WW_Pin1_4	113	118	PF00397	0.766
DOC_WW_Pin1_4	252	257	PF00397	0.755
LIG_14-3-3_CanoR_1	113	117	PF00244	0.654
LIG_14-3-3_CanoR_1	145	155	PF00244	0.535
LIG_14-3-3_CanoR_1	159	163	PF00244	0.585
LIG_14-3-3_CanoR_1	250	258	PF00244	0.533
LIG_14-3-3_CanoR_1	266	273	PF00244	0.444
LIG_14-3-3_CanoR_1	277	286	PF00244	0.421
LIG_14-3-3_CanoR_1	338	343	PF00244	0.335
LIG_14-3-3_CanoR_1	378	385	PF00244	0.348
LIG_14-3-3_CanoR_1	90	99	PF00244	0.504
LIG_Actin_RPEL_3	349	368	PF02755	0.453
LIG_APCC_ABBAyCdc20_2	325	331	PF00400	0.335
LIG_BIR_II_1	1	5	PF00653	0.578
LIG_BIR_III_1	1	5	PF00653	0.578
LIG_BIR_III_3	1	5	PF00653	0.578
LIG_Clathr_ClatBox_1	227	231	PF01394	0.719
LIG_FHA_1	18	24	PF00498	0.513
LIG_FHA_1	199	205	PF00498	0.672
LIG_FHA_1	262	268	PF00498	0.679
LIG_FHA_1	362	368	PF00498	0.335
LIG_FHA_2	209	215	PF00498	0.525
LIG_FHA_2	379	385	PF00498	0.341
LIG_FHA_2	392	398	PF00498	0.378
LIG_LIR_Apic_2	37	42	PF02991	0.643
LIG_LIR_Gen_1	363	372	PF02991	0.335
LIG_LIR_Gen_1	8	18	PF02991	0.526
LIG_LIR_Nem_3	116	122	PF02991	0.579
LIG_LIR_Nem_3	15	21	PF02991	0.529
LIG_LIR_Nem_3	363	368	PF02991	0.343
LIG_LIR_Nem_3	8	13	PF02991	0.529
LIG_PCNA_yPIPBox_3	325	337	PF02747	0.453
LIG_Pex14_1	410	414	PF04695	0.335
LIG_Rb_LxCxE_1	341	357	PF01857	0.355
LIG_RPA_C_Fungi	57	69	PF08784	0.450
LIG_SH2_CRK	18	22	PF00017	0.565
LIG_SH2_CRK	365	369	PF00017	0.354
LIG_SH2_CRK	414	418	PF00017	0.335
LIG_SH2_STAP1	365	369	PF00017	0.335
LIG_SH2_STAP1	438	442	PF00017	0.335
LIG_SH2_STAP1	45	49	PF00017	0.526
LIG_SH2_STAT5	63	66	PF00017	0.630
LIG_SH3_2	108	113	PF14604	0.755
LIG_SH3_3	105	111	PF00018	0.649
LIG_SH3_3	253	259	PF00018	0.621
LIG_SH3_3	317	323	PF00018	0.389
LIG_SUMO_SIM_anti_2	295	301	PF11976	0.340
LIG_TYR_ITIM	16	21	PF00017	0.520
LIG_TYR_ITIM	301	306	PF00017	0.335
MOD_CK1_1	216	222	PF00069	0.727
MOD_CK1_1	252	258	PF00069	0.682
MOD_CK1_1	261	267	PF00069	0.770
MOD_CK1_1	269	275	PF00069	0.613
MOD_CK1_1	92	98	PF00069	0.640
MOD_CK2_1	145	151	PF00069	0.713
MOD_CK2_1	157	163	PF00069	0.674
MOD_CK2_1	236	242	PF00069	0.529
MOD_CK2_1	391	397	PF00069	0.389
MOD_CK2_1	5	11	PF00069	0.666
MOD_DYRK1A_RPxSP_1	113	117	PF00069	0.768
MOD_GlcNHglycan	126	129	PF01048	0.646
MOD_GlcNHglycan	134	137	PF01048	0.666
MOD_GlcNHglycan	198	201	PF01048	0.636
MOD_GlcNHglycan	213	218	PF01048	0.590
MOD_GlcNHglycan	242	245	PF01048	0.670
MOD_GlcNHglycan	260	263	PF01048	0.699
MOD_GlcNHglycan	268	271	PF01048	0.597
MOD_GlcNHglycan	277	280	PF01048	0.306
MOD_GlcNHglycan	313	316	PF01048	0.335
MOD_GlcNHglycan	370	373	PF01048	0.335
MOD_GlcNHglycan	92	95	PF01048	0.694
MOD_GSK3_1	113	120	PF00069	0.567
MOD_GSK3_1	132	139	PF00069	0.577
MOD_GSK3_1	153	160	PF00069	0.691
MOD_GSK3_1	198	205	PF00069	0.577
MOD_GSK3_1	236	243	PF00069	0.728
MOD_GSK3_1	254	261	PF00069	0.746
MOD_GSK3_1	262	269	PF00069	0.681
MOD_GSK3_1	391	398	PF00069	0.405
MOD_GSK3_1	78	85	PF00069	0.571
MOD_GSK3_1	90	97	PF00069	0.635
MOD_NEK2_1	17	22	PF00069	0.502
MOD_NEK2_1	260	265	PF00069	0.702
MOD_NEK2_1	354	359	PF00069	0.311
MOD_NEK2_1	368	373	PF00069	0.387
MOD_NEK2_2	118	123	PF00069	0.536
MOD_PKA_1	378	384	PF00069	0.335
MOD_PKA_2	112	118	PF00069	0.548
MOD_PKA_2	158	164	PF00069	0.608
MOD_PKA_2	208	214	PF00069	0.804
MOD_PKA_2	249	255	PF00069	0.550
MOD_PKA_2	311	317	PF00069	0.348
MOD_PKA_2	377	383	PF00069	0.335
MOD_PKA_2	89	95	PF00069	0.626
MOD_PKA_2	97	103	PF00069	0.533
MOD_Plk_2-3	5	11	PF00069	0.660
MOD_Plk_4	12	18	PF00069	0.516
MOD_Plk_4	338	344	PF00069	0.507
MOD_Plk_4	82	88	PF00069	0.503
MOD_ProDKin_1	113	119	PF00069	0.770
MOD_ProDKin_1	252	258	PF00069	0.752
MOD_SUMO_rev_2	423	431	PF00179	0.344
MOD_SUMO_rev_2	448	453	PF00179	0.459
TRG_DiLeu_BaEn_1	346	351	PF01217	0.335
TRG_ENDOCYTIC_2	10	13	PF00928	0.526
TRG_ENDOCYTIC_2	18	21	PF00928	0.514
TRG_ENDOCYTIC_2	303	306	PF00928	0.335
TRG_ENDOCYTIC_2	365	368	PF00928	0.354
TRG_ENDOCYTIC_2	414	417	PF00928	0.341
TRG_ER_diArg_1	185	188	PF00400	0.459
TRG_ER_diArg_1	286	288	PF00400	0.335
TRG_ER_diArg_1	400	403	PF00400	0.335
TRG_ER_diLys_1	459	463	PF00400	0.696
TRG_NES_CRM1_1	331	346	PF08389	0.453
TRG_Pf-PMV_PEXEL_1	334	339	PF00026	0.453
TRG_Pf-PMV_PEXEL_1	347	352	PF00026	0.277
TRG_Pf-PMV_PEXEL_1	383	387	PF00026	0.335
TRG_Pf-PMV_PEXEL_1	429	434	PF00026	0.423
TRG_Pf-PMV_PEXEL_1	52	56	PF00026	0.608
TRG_Pf-PMV_PEXEL_1	7	11	PF00026	0.650

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P322	Leptomonas seymouri	44%	94%
A0A3S7WZS2	Leishmania donovani	86%	99%
A4HEW7	Leishmania braziliensis	72%	100%
A4I241	Leishmania infantum	86%	99%
Q4Q982	Leishmania major	83%	100%