PORR domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AXQ5_LEIMU

TriTrypDb:

LmxM.25.1730

Length:

313

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AXQ5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AXQ5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	129	131	PF00675	0.399
CLV_NRD_NRD_1	298	300	PF00675	0.359
CLV_NRD_NRD_1	310	312	PF00675	0.533
CLV_NRD_NRD_1	60	62	PF00675	0.633
CLV_PCSK_KEX2_1	298	300	PF00082	0.359
CLV_PCSK_KEX2_1	60	62	PF00082	0.633
CLV_PCSK_SKI1_1	12	16	PF00082	0.690
CLV_PCSK_SKI1_1	130	134	PF00082	0.515
CLV_PCSK_SKI1_1	258	262	PF00082	0.503
CLV_PCSK_SKI1_1	28	32	PF00082	0.739
CLV_PCSK_SKI1_1	298	302	PF00082	0.501
DEG_APCC_DBOX_1	136	144	PF00400	0.516
DEG_SPOP_SBC_1	227	231	PF00917	0.522
DEG_SPOP_SBC_1	83	87	PF00917	0.790
DOC_CKS1_1	70	75	PF01111	0.561
DOC_PP2B_LxvP_1	145	148	PF13499	0.417
DOC_PP4_FxxP_1	52	55	PF00568	0.527
DOC_USP7_MATH_1	250	254	PF00917	0.464
DOC_USP7_MATH_1	83	87	PF00917	0.687
DOC_WW_Pin1_4	123	128	PF00397	0.458
DOC_WW_Pin1_4	214	219	PF00397	0.720
DOC_WW_Pin1_4	47	52	PF00397	0.657
DOC_WW_Pin1_4	63	68	PF00397	0.644
DOC_WW_Pin1_4	69	74	PF00397	0.657
DOC_WW_Pin1_4	87	92	PF00397	0.740
LIG_14-3-3_CanoR_1	28	36	PF00244	0.616
LIG_14-3-3_CanoR_1	298	304	PF00244	0.369
LIG_BRCT_BRCA1_1	291	295	PF00533	0.299
LIG_CtBP_PxDLS_1	73	77	PF00389	0.559
LIG_deltaCOP1_diTrp_1	247	251	PF00928	0.367
LIG_FHA_1	113	119	PF00498	0.473
LIG_FHA_1	228	234	PF00498	0.614
LIG_FHA_2	230	236	PF00498	0.545
LIG_IRF3_LxIS_1	251	257	PF10401	0.495
LIG_LIR_Apic_2	195	200	PF02991	0.549
LIG_LIR_Apic_2	50	55	PF02991	0.680
LIG_LIR_Gen_1	247	256	PF02991	0.383
LIG_LIR_Gen_1	33	44	PF02991	0.663
LIG_LIR_Nem_3	120	125	PF02991	0.406
LIG_LIR_Nem_3	247	251	PF02991	0.367
LIG_LIR_Nem_3	33	39	PF02991	0.657
LIG_LYPXL_yS_3	267	270	PF13949	0.541
LIG_MAD2	131	139	PF02301	0.540
LIG_MYND_1	99	103	PF01753	0.568
LIG_MYND_3	191	195	PF01753	0.530
LIG_REV1ctd_RIR_1	280	290	PF16727	0.506
LIG_SH2_STAT5	243	246	PF00017	0.337
LIG_SH3_3	166	172	PF00018	0.525
LIG_SH3_3	64	70	PF00018	0.619
LIG_SUMO_SIM_par_1	102	107	PF11976	0.537
LIG_TRAF2_1	139	142	PF00917	0.520
LIG_UBA3_1	181	189	PF00899	0.401
MOD_CDC14_SPxK_1	92	95	PF00782	0.484
MOD_CDK_SPK_2	214	219	PF00069	0.438
MOD_CDK_SPxK_1	89	95	PF00069	0.488
MOD_CDK_SPxxK_3	123	130	PF00069	0.427
MOD_CK1_1	126	132	PF00069	0.422
MOD_CK1_1	229	235	PF00069	0.460
MOD_CK1_1	77	83	PF00069	0.720
MOD_CK1_1	85	91	PF00069	0.554
MOD_CK2_1	229	235	PF00069	0.587
MOD_CK2_1	72	78	PF00069	0.759
MOD_DYRK1A_RPxSP_1	123	127	PF00069	0.454
MOD_GlcNHglycan	163	166	PF01048	0.559
MOD_GlcNHglycan	223	226	PF01048	0.690
MOD_GSK3_1	156	163	PF00069	0.563
MOD_GSK3_1	250	257	PF00069	0.492
MOD_GSK3_1	28	35	PF00069	0.651
MOD_GSK3_1	65	72	PF00069	0.672
MOD_GSK3_1	79	86	PF00069	0.601
MOD_N-GLC_1	254	259	PF02516	0.502
MOD_N-GLC_1	307	312	PF02516	0.475
MOD_NEK2_1	156	161	PF00069	0.481
MOD_NEK2_1	174	179	PF00069	0.344
MOD_NEK2_1	226	231	PF00069	0.646
MOD_NEK2_1	30	35	PF00069	0.725
MOD_NEK2_1	307	312	PF00069	0.539
MOD_NEK2_1	38	43	PF00069	0.544
MOD_PKA_2	39	45	PF00069	0.615
MOD_Plk_4	239	245	PF00069	0.378
MOD_Plk_4	291	297	PF00069	0.443
MOD_ProDKin_1	123	129	PF00069	0.451
MOD_ProDKin_1	214	220	PF00069	0.720
MOD_ProDKin_1	47	53	PF00069	0.652
MOD_ProDKin_1	63	69	PF00069	0.645
MOD_ProDKin_1	87	93	PF00069	0.739
MOD_SUMO_rev_2	253	262	PF00179	0.510
TRG_DiLeu_BaEn_1	107	112	PF01217	0.526
TRG_DiLeu_BaLyEn_6	52	57	PF01217	0.676
TRG_ENDOCYTIC_2	267	270	PF00928	0.535
TRG_ENDOCYTIC_2	279	282	PF00928	0.314
TRG_ER_diArg_1	297	299	PF00400	0.356
TRG_NES_CRM1_1	107	120	PF08389	0.460
TRG_Pf-PMV_PEXEL_1	299	304	PF00026	0.420

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMC8	Leptomonas seymouri	56%	97%
A0A1X0NY85	Trypanosomatidae	35%	100%
A0A3S7WZA0	Leishmania donovani	82%	98%
A0A422NGK2	Trypanosoma rangeli	35%	100%
A4HEG9	Leishmania braziliensis	66%	100%
A4I1M1	Leishmania infantum	82%	98%
C9ZK64	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	96%
Q4Q9R6	Leishmania major	83%	100%
V5BHV8	Trypanosoma cruzi	35%	100%