Complex1_LYR_dom domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AXH7_LEIMU

TriTrypDb:

LmxM.25.0990

Length:

162


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005739	mitochondrion	5	1
GO:0005929	cilium	4	1
GO:0020023	kinetoplast	2	1
GO:0042995	cell projection	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1
GO:0120025	plasma membrane bounded cell projection	3	1

E9AXH7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AXH7


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	121	123	PF00675	0.491
CLV_NRD_NRD_1	159	161	PF00675	0.521
CLV_PCSK_KEX2_1	121	123	PF00082	0.518
CLV_PCSK_PC1ET2_1	121	123	PF00082	0.534
DEG_APCC_DBOX_1	129	137	PF00400	0.533
DEG_Nend_Nbox_1	1	3	PF02207	0.668
DOC_MAPK_gen_1	48	58	PF00069	0.328
DOC_MAPK_MEF2A_6	51	58	PF00069	0.328
DOC_MAPK_MEF2A_6	93	102	PF00069	0.328
DOC_MAPK_NFAT4_5	51	59	PF00069	0.328
DOC_PP2B_LxvP_1	21	24	PF13499	0.508
DOC_PP2B_LxvP_1	59	62	PF13499	0.363
DOC_SPAK_OSR1_1	77	81	PF12202	0.328
DOC_USP7_MATH_1	101	105	PF00917	0.363
DOC_USP7_UBL2_3	143	147	PF12436	0.634
LIG_14-3-3_CanoR_1	3	7	PF00244	0.636
LIG_14-3-3_CanoR_1	45	51	PF00244	0.449
LIG_CaM_IQ_9	99	115	PF13499	0.344
LIG_FHA_1	154	160	PF00498	0.628
LIG_LIR_Gen_1	76	86	PF02991	0.315
LIG_LIR_Nem_3	152	157	PF02991	0.501
LIG_LIR_Nem_3	76	81	PF02991	0.315
LIG_SH2_GRB2like	153	156	PF00017	0.503
LIG_SH2_STAT5	157	160	PF00017	0.542
LIG_SH3_3	35	41	PF00018	0.456
LIG_SH3_3	55	61	PF00018	0.328
LIG_SH3_CIN85_PxpxPR_1	125	130	PF14604	0.554
MOD_GlcNHglycan	4	7	PF01048	0.693
MOD_GlcNHglycan	62	65	PF01048	0.363
MOD_GSK3_1	101	108	PF00069	0.328
MOD_GSK3_1	11	18	PF00069	0.573
MOD_NEK2_1	1	6	PF00069	0.618
MOD_NEK2_1	11	16	PF00069	0.638
MOD_PKA_2	2	8	PF00069	0.619
MOD_Plk_1	105	111	PF00069	0.328
MOD_Plk_4	11	17	PF00069	0.644
MOD_Plk_4	153	159	PF00069	0.494
TRG_ENDOCYTIC_2	146	149	PF00928	0.476
TRG_NLS_MonoExtC_3	120	125	PF00514	0.494
TRG_Pf-PMV_PEXEL_1	113	118	PF00026	0.466


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILI5	Leptomonas seymouri	88%	100%
A0A0S4JY75	Bodo saltans	75%	100%
A0A1X0NLU6	Trypanosomatidae	87%	96%
A0A3R7MRN4	Trypanosoma rangeli	82%	100%
A0A3S7WYZ6	Leishmania donovani	98%	100%
A4HE34	Leishmania braziliensis	94%	100%
A4I1E0	Leishmania infantum	98%	100%
C9ZJV6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	78%	100%
Q4Q9Z5	Leishmania major	98%	100%
V5AWD4	Trypanosoma cruzi	85%	100%