Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AXE3_LEIMU

TriTrypDb:

LmxM.25.0660

Length:


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	7
GO:0110165	cellular anatomical entity	1	7

E9AXE3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AXE3


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	3	5	PF00675	0.448
CLV_PCSK_KEX2_1	3	5	PF00082	0.448
DEG_Nend_Nbox_1	1	3	PF02207	0.634
DOC_PP2B_LxvP_1	16	19	PF13499	0.607
DOC_PP4_FxxP_1	17	20	PF00568	0.605
DOC_PP4_FxxP_1	26	29	PF00568	0.606
DOC_WW_Pin1_4	44	49	PF00397	0.360
LIG_14-3-3_CanoR_1	9	19	PF00244	0.627
LIG_BRCT_BRCA1_1	13	17	PF00533	0.609
LIG_BRCT_BRCA1_1	34	38	PF00533	0.596
LIG_deltaCOP1_diTrp_1	90	94	PF00928	0.399
LIG_FHA_1	11	17	PF00498	0.616
LIG_FHA_2	31	37	PF00498	0.571
LIG_LIR_Apic_2	14	20	PF02991	0.605
LIG_LIR_Apic_2	22	28	PF02991	0.606
LIG_LIR_Nem_3	35	41	PF02991	0.401
LIG_LIR_Nem_3	90	95	PF02991	0.431
LIG_Pex14_2	38	42	PF04695	0.300
LIG_SH2_SRC	54	57	PF00017	0.410
LIG_SH2_STAP1	78	82	PF00017	0.396
LIG_SH2_STAT3	60	63	PF00017	0.416
LIG_SH2_STAT3	73	76	PF00017	0.358
LIG_SH2_STAT5	54	57	PF00017	0.410
LIG_SH2_STAT5	78	81	PF00017	0.386
MOD_GlcNHglycan	21	24	PF01048	0.449
MOD_GSK3_1	30	37	PF00069	0.572
MOD_NEK2_1	2	7	PF00069	0.649
MOD_NEK2_1	34	39	PF00069	0.573
MOD_PKA_2	2	8	PF00069	0.647
MOD_Plk_4	34	40	PF00069	0.464
MOD_ProDKin_1	44	50	PF00069	0.360
TRG_ENDOCYTIC_2	86	89	PF00928	0.382
TRG_ER_diArg_1	2	4	PF00400	0.658


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I4J9	Leptomonas seymouri	92%	100%
A0A3S5H7E3	Leishmania donovani	98%	100%
A4HEF2	Leishmania braziliensis	96%	100%
A4I1A7	Leishmania infantum	98%	100%
Q4QA29	Leishmania major	98%	100%
V5BSX9	Trypanosoma cruzi	83%	100%