LeishMANIAdb
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Electron transfer flavoprotein subunit beta

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Electron transfer flavoprotein subunit beta
Gene product:
electron transfer flavoprotein, putative
Species:
Leishmania mexicana
UniProt:
E9AX88_LEIMU
TriTrypDb:
LmxM.25.0120
Length:
258

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0005759 mitochondrial matrix 5 12
GO:0031974 membrane-enclosed lumen 2 12
GO:0043233 organelle lumen 3 12
GO:0070013 intracellular organelle lumen 4 12
GO:0110165 cellular anatomical entity 1 12

Expansion

Sequence features

E9AX88
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AX88

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 12
GO:0009055 electron transfer activity 3 12
GO:0016491 oxidoreductase activity 2 12

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 204 206 PF00675 0.252
CLV_NRD_NRD_1 235 237 PF00675 0.501
CLV_PCSK_KEX2_1 16 18 PF00082 0.342
CLV_PCSK_PC1ET2_1 16 18 PF00082 0.342
CLV_PCSK_SKI1_1 161 165 PF00082 0.301
CLV_PCSK_SKI1_1 212 216 PF00082 0.300
CLV_Separin_Metazoa 76 80 PF03568 0.463
DEG_Nend_Nbox_1 1 3 PF02207 0.556
DEG_SCF_FBW7_1 219 226 PF00400 0.576
DOC_CKS1_1 190 195 PF01111 0.458
DOC_MAPK_gen_1 212 221 PF00069 0.600
DOC_MAPK_gen_1 236 242 PF00069 0.473
DOC_MAPK_HePTP_8 209 221 PF00069 0.460
DOC_MAPK_MEF2A_6 173 180 PF00069 0.538
DOC_MAPK_MEF2A_6 212 221 PF00069 0.537
DOC_PP2B_LxvP_1 145 148 PF13499 0.463
DOC_PP2B_LxvP_1 178 181 PF13499 0.463
DOC_USP7_MATH_1 98 102 PF00917 0.557
DOC_USP7_UBL2_3 155 159 PF12436 0.529
DOC_USP7_UBL2_3 203 207 PF12436 0.452
DOC_USP7_UBL2_3 237 241 PF12436 0.479
DOC_USP7_UBL2_3 24 28 PF12436 0.451
DOC_WW_Pin1_4 134 139 PF00397 0.448
DOC_WW_Pin1_4 189 194 PF00397 0.458
DOC_WW_Pin1_4 219 224 PF00397 0.540
LIG_APCC_ABBA_1 41 46 PF00400 0.452
LIG_EH_1 41 45 PF12763 0.452
LIG_FHA_1 135 141 PF00498 0.449
LIG_FHA_1 164 170 PF00498 0.460
LIG_FHA_1 20 26 PF00498 0.412
LIG_FHA_1 209 215 PF00498 0.492
LIG_FHA_1 220 226 PF00498 0.447
LIG_FHA_2 227 233 PF00498 0.540
LIG_FHA_2 242 248 PF00498 0.410
LIG_LIR_Gen_1 246 257 PF02991 0.405
LIG_LIR_Nem_3 192 198 PF02991 0.463
LIG_LIR_Nem_3 246 252 PF02991 0.398
LIG_NRBOX 140 146 PF00104 0.452
LIG_SH2_CRK 249 253 PF00017 0.428
LIG_SH2_STAP1 21 25 PF00017 0.405
LIG_SH2_STAT5 21 24 PF00017 0.328
LIG_SH2_STAT5 8 11 PF00017 0.415
LIG_SH3_3 190 196 PF00018 0.452
LIG_SH3_3 227 233 PF00018 0.475
LIG_SH3_3 89 95 PF00018 0.538
LIG_SUMO_SIM_par_1 174 179 PF11976 0.513
LIG_SUMO_SIM_par_1 62 68 PF11976 0.453
LIG_TRAF2_1 48 51 PF00917 0.452
LIG_UBA3_1 1 10 PF00899 0.578
LIG_UBA3_1 118 127 PF00899 0.477
MOD_CDK_SPK_2 189 194 PF00069 0.452
MOD_CK1_1 226 232 PF00069 0.526
MOD_CK1_1 37 43 PF00069 0.538
MOD_CK2_1 151 157 PF00069 0.477
MOD_CK2_1 226 232 PF00069 0.504
MOD_CK2_1 241 247 PF00069 0.369
MOD_Cter_Amidation 70 73 PF01082 0.301
MOD_GSK3_1 219 226 PF00069 0.511
MOD_GSK3_1 228 235 PF00069 0.566
MOD_NEK2_1 1 6 PF00069 0.536
MOD_PKA_1 161 167 PF00069 0.501
MOD_Plk_1 176 182 PF00069 0.538
MOD_Plk_1 19 25 PF00069 0.384
MOD_ProDKin_1 134 140 PF00069 0.448
MOD_ProDKin_1 189 195 PF00069 0.458
MOD_ProDKin_1 219 225 PF00069 0.545
MOD_SUMO_rev_2 154 164 PF00179 0.478
MOD_SUMO_rev_2 210 217 PF00179 0.499
MOD_SUMO_rev_2 51 61 PF00179 0.452
TRG_DiLeu_BaEn_4 50 56 PF01217 0.477
TRG_ENDOCYTIC_2 249 252 PF00928 0.409
TRG_ENDOCYTIC_2 8 11 PF00928 0.472
TRG_NLS_MonoExtC_3 204 210 PF00514 0.452
TRG_NLS_MonoExtN_4 203 209 PF00514 0.452

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I8P0 Leptomonas seymouri 85% 100%
A0A0S4IV36 Bodo saltans 73% 96%
A0A1X0P4J7 Trypanosomatidae 74% 96%
A0A3R7NC11 Trypanosoma rangeli 71% 96%
A0A3S7WYW8 Leishmania donovani 97% 100%
A2XQV4 Oryza sativa subsp. indica 51% 100%
A4HDV9 Leishmania braziliensis 89% 100%
A4I154 Leishmania infantum 97% 100%
A7ZHD4 Escherichia coli O139:H28 (strain E24377A / ETEC) 24% 100%
A7ZVZ3 Escherichia coli O9:H4 (strain HS) 24% 100%
A9MYK3 Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) 25% 100%
B1IRD5 Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks) 24% 100%
B1LFX5 Escherichia coli (strain SMS-3-5 / SECEC) 24% 100%
B1XBG6 Escherichia coli (strain K12 / DH10B) 24% 100%
B4T6K2 Salmonella newport (strain SL254) 25% 100%
B5BL59 Salmonella paratyphi A (strain AKU_12601) 25% 100%
B5F756 Salmonella agona (strain SL483) 25% 100%
B5FHH0 Salmonella dublin (strain CT_02021853) 25% 100%
B5RGA8 Salmonella gallinarum (strain 287/91 / NCTC 13346) 25% 100%
B6HYZ2 Escherichia coli (strain SE11) 24% 100%
B7L4G4 Escherichia coli (strain 55989 / EAEC) 24% 100%
B7LWN2 Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73) 24% 100%
B7M0D8 Escherichia coli O8 (strain IAI1) 24% 100%
B7MAG4 Escherichia coli O45:K1 (strain S88 / ExPEC) 24% 100%
B7MNP8 Escherichia coli O81 (strain ED1a) 24% 100%
B7N7R6 Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) 24% 100%
B7NHE5 Escherichia coli O7:K1 (strain IAI39 / ExPEC) 24% 100%
B7UI87 Escherichia coli O127:H6 (strain E2348/69 / EPEC) 24% 100%
C4ZPW7 Escherichia coli (strain K12 / MC4100 / BW2952) 24% 100%
D0A5D9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 64% 96%
G3KIM7 Anaerotignum propionicum 30% 97%
H6LBB0 Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1) 25% 98%
H6LGM7 Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1) 29% 98%
O33095 Mycobacterium leprae (strain TN) 30% 97%
O85691 Megasphaera elsdenii 30% 96%
P09818 Rhizobium meliloti (strain 1021) 30% 88%
P26482 Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571) 28% 92%
P38117 Homo sapiens 51% 100%
P38975 Paracoccus denitrificans 53% 100%
P42940 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 44% 99%
P52040 Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) 32% 100%
P53570 Methylophilus methylotrophus 29% 98%
P53575 Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110) 55% 100%
P53576 Azotobacter vinelandii 30% 92%
P53577 Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110) 28% 90%
P59673 Shigella flexneri 24% 100%
P60566 Escherichia coli (strain K12) 24% 100%
P60567 Escherichia coli O157:H7 24% 100%
P64098 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) 31% 97%
P76201 Escherichia coli (strain K12) 26% 100%
P94550 Bacillus subtilis (strain 168) 38% 100%
P97089 Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIMB 9385 / NCA 3814 / NCTC 13789 / WDCM 00135 / 2032) 37% 99%
P9WNG6 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 31% 97%
P9WNG7 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 31% 97%
Q05559 Rhizobium leguminosarum bv. phaseoli 28% 92%
Q0AZ34 Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen) 39% 100%
Q0T8F3 Shigella flexneri serotype 5b (strain 8401) 24% 100%
Q0TLU8 Escherichia coli O6:K15:H31 (strain 536 / UPEC) 24% 100%
Q2TBV3 Bos taurus 50% 100%
Q4QA84 Leishmania major 96% 100%
Q53210 Sinorhizobium fredii (strain NBRC 101917 / NGR234) 29% 91%
Q54YZ4 Dictyostelium discoideum 48% 100%
Q5PIN4 Salmonella paratyphi A (strain ATCC 9150 / SARB42) 25% 100%
Q5RFK0 Pongo abelii 51% 100%
Q68FU3 Rattus norvegicus 51% 100%
Q6UAQ8 Sus scrofa 50% 100%
Q7F9U3 Oryza sativa subsp. japonica 51% 100%
Q8FLA3 Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) 24% 100%
Q8Z9L0 Salmonella typhi 25% 100%
Q8ZRX0 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 25% 100%
Q9DCW4 Mus musculus 52% 100%
Q9HZP6 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 53% 100%
Q9LSW8 Arabidopsis thaliana 50% 100%
Q9UTH2 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 40% 100%
V5DPC1 Trypanosoma cruzi 75% 96%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS