Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AX79_LEIMU

TriTrypDb:

LmxM.24.2330

Length:

258

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AX79

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AX79

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	113	115	PF00675	0.353
CLV_NRD_NRD_1	233	235	PF00675	0.478
CLV_NRD_NRD_1	238	240	PF00675	0.468
CLV_NRD_NRD_1	243	245	PF00675	0.484
CLV_NRD_NRD_1	254	256	PF00675	0.558
CLV_NRD_NRD_1	43	45	PF00675	0.466
CLV_NRD_NRD_1	66	68	PF00675	0.424
CLV_PCSK_FUR_1	236	240	PF00082	0.475
CLV_PCSK_KEX2_1	232	234	PF00082	0.480
CLV_PCSK_KEX2_1	237	239	PF00082	0.475
CLV_PCSK_KEX2_1	243	245	PF00082	0.486
CLV_PCSK_KEX2_1	254	256	PF00082	0.531
CLV_PCSK_PC1ET2_1	232	234	PF00082	0.480
CLV_PCSK_PC1ET2_1	237	239	PF00082	0.475
CLV_PCSK_PC7_1	233	239	PF00082	0.478
CLV_PCSK_SKI1_1	115	119	PF00082	0.531
CLV_PCSK_SKI1_1	122	126	PF00082	0.537
CLV_PCSK_SKI1_1	243	247	PF00082	0.487
CLV_PCSK_SKI1_1	31	35	PF00082	0.615
CLV_PCSK_SKI1_1	37	41	PF00082	0.632
CLV_PCSK_SKI1_1	55	59	PF00082	0.491
DEG_Nend_UBRbox_2	1	3	PF02207	0.645
DOC_MAPK_gen_1	67	75	PF00069	0.618
DOC_USP7_MATH_1	113	117	PF00917	0.361
DOC_USP7_UBL2_3	68	72	PF12436	0.481
LIG_14-3-3_CanoR_1	114	121	PF00244	0.478
LIG_14-3-3_CanoR_1	138	144	PF00244	0.458
LIG_APCC_ABBAyCdc20_2	122	128	PF00400	0.456
LIG_BRCT_BRCA1_1	99	103	PF00533	0.331
LIG_CaM_IQ_9	194	209	PF13499	0.481
LIG_deltaCOP1_diTrp_1	59	64	PF00928	0.455
LIG_FHA_1	38	44	PF00498	0.385
LIG_FHA_1	52	58	PF00498	0.529
LIG_FHA_2	15	21	PF00498	0.510
LIG_FHA_2	156	162	PF00498	0.406
LIG_LIR_Gen_1	100	109	PF02991	0.331
LIG_LIR_Gen_1	131	137	PF02991	0.566
LIG_LIR_Gen_1	58	66	PF02991	0.507
LIG_LIR_Nem_3	128	132	PF02991	0.553
LIG_LIR_Nem_3	36	41	PF02991	0.427
LIG_LIR_Nem_3	58	64	PF02991	0.515
LIG_NRBOX	161	167	PF00104	0.453
LIG_SH2_NCK_1	84	88	PF00017	0.323
LIG_SH2_STAT3	130	133	PF00017	0.409
LIG_SH2_STAT5	74	77	PF00017	0.583
LIG_TRAF2_1	63	66	PF00917	0.332
MOD_CK2_1	139	145	PF00069	0.483
MOD_GlcNHglycan	115	118	PF01048	0.449
MOD_GlcNHglycan	99	102	PF01048	0.428
MOD_GSK3_1	109	116	PF00069	0.343
MOD_GSK3_1	51	58	PF00069	0.552
MOD_GSK3_1	93	100	PF00069	0.467
MOD_NEK2_1	109	114	PF00069	0.340
MOD_NEK2_1	165	170	PF00069	0.419
MOD_PIKK_1	165	171	PF00454	0.423
MOD_PIKK_1	79	85	PF00454	0.365
MOD_PKA_2	113	119	PF00069	0.464
MOD_PKA_2	93	99	PF00069	0.424
MOD_SUMO_rev_2	142	151	PF00179	0.449
MOD_SUMO_rev_2	20	26	PF00179	0.379
MOD_SUMO_rev_2	62	70	PF00179	0.375
MOD_SUMO_rev_2	91	101	PF00179	0.406
TRG_ENDOCYTIC_2	132	135	PF00928	0.445
TRG_ER_diArg_1	236	239	PF00400	0.479
TRG_Pf-PMV_PEXEL_1	31	36	PF00026	0.412

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3B7	Leptomonas seymouri	38%	98%
A0A3Q8IN13	Leishmania donovani	84%	100%
A4HDU4	Leishmania braziliensis	70%	100%
A4I141	Leishmania infantum	85%	100%
Q4QA97	Leishmania major	84%	100%