LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9AX61_LEIMU
TriTrypDb:
LmxM.24.2150
Length:
142

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AX61
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AX61

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 118 120 PF00675 0.550
CLV_NRD_NRD_1 12 14 PF00675 0.508
CLV_NRD_NRD_1 6 8 PF00675 0.724
CLV_PCSK_KEX2_1 14 16 PF00082 0.534
CLV_PCSK_PC1ET2_1 14 16 PF00082 0.534
DOC_MAPK_MEF2A_6 133 140 PF00069 0.502
DOC_PP4_FxxP_1 118 121 PF00568 0.566
DOC_USP7_UBL2_3 74 78 PF12436 0.398
LIG_14-3-3_CanoR_1 103 109 PF00244 0.417
LIG_14-3-3_CanoR_1 124 132 PF00244 0.508
LIG_14-3-3_CanoR_1 63 67 PF00244 0.695
LIG_deltaCOP1_diTrp_1 79 87 PF00928 0.600
LIG_FHA_1 90 96 PF00498 0.633
LIG_FHA_2 74 80 PF00498 0.516
LIG_LIR_Apic_2 117 121 PF02991 0.604
LIG_SH2_STAT5 86 89 PF00017 0.617
LIG_SUMO_SIM_par_1 23 29 PF11976 0.505
LIG_WRC_WIRS_1 115 120 PF05994 0.604
MOD_CK1_1 6 12 PF00069 0.733
MOD_CK1_1 65 71 PF00069 0.763
MOD_GSK3_1 3 10 PF00069 0.630
MOD_GSK3_1 61 68 PF00069 0.642
MOD_NEK2_1 123 128 PF00069 0.507
MOD_NEK2_1 61 66 PF00069 0.667
MOD_NEK2_2 73 78 PF00069 0.402
MOD_PIKK_1 46 52 PF00454 0.708
MOD_PIKK_1 7 13 PF00454 0.525
MOD_PKA_1 7 13 PF00069 0.642
MOD_PKA_2 123 129 PF00069 0.586
MOD_PKA_2 6 12 PF00069 0.635
MOD_PKA_2 62 68 PF00069 0.678
MOD_Plk_1 98 104 PF00069 0.711
MOD_Plk_2-3 51 57 PF00069 0.648
MOD_SUMO_for_1 111 114 PF00179 0.446
TRG_DiLeu_BaEn_1 23 28 PF01217 0.499
TRG_DiLeu_BaLyEn_6 22 27 PF01217 0.500

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IBH9 Leishmania donovani 77% 98%
A4HDS6 Leishmania braziliensis 55% 100%
A4I124 Leishmania infantum 78% 98%
Q4QAB5 Leishmania major 79% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS