3-oxoacyl-(Acyl-carrier protein) reductase,putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

3-oxoacyl-(acyl-carrier protein) reductase, putative

Species:

Leishmania mexicana

UniProt:

E9AX49_LEIMU

TriTrypDb:

LmxM.24.2030

Length:

259

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 16

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AX49

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AX49

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	8
GO:0004312	fatty acid synthase activity	5	4
GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	5	4
GO:0016491	oxidoreductase activity	2	8
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	3	4
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4	4
GO:0016740	transferase activity	2	4
GO:0016746	acyltransferase activity	3	4
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	4	4

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	12	16	PF00082	0.474
CLV_PCSK_SKI1_1	83	87	PF00082	0.423
DEG_Nend_UBRbox_3	1	3	PF02207	0.684
DOC_CKS1_1	201	206	PF01111	0.402
DOC_CYCLIN_yCln2_LP_2	205	208	PF00134	0.436
DOC_MAPK_gen_1	103	111	PF00069	0.421
DOC_MAPK_MEF2A_6	172	180	PF00069	0.436
DOC_PP2B_LxvP_1	178	181	PF13499	0.436
DOC_PP2B_LxvP_1	205	208	PF13499	0.436
DOC_USP7_UBL2_3	99	103	PF12436	0.456

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A023I4C8	Penicillium roqueforti	27%	79%
A0A023I4F1	Penicillium roqueforti	26%	76%
A0A084R1K2	Stachybotrys chlorohalonata (strain IBT 40285)	25%	100%
A0A097ZPC9	Emericella variicolor	27%	100%
A0A0F7U1Z1	Penicillium brasilianum	27%	100%
A0A0N0P8F5	Leptomonas seymouri	23%	88%
A0A0N1HTL2	Leptomonas seymouri	82%	100%
A0A0N1I1P8	Leptomonas seymouri	25%	76%
A0A0N1PCK0	Leptomonas seymouri	29%	100%
A0A0N1PDE1	Leptomonas seymouri	26%	100%

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