DUF4476 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AX25_LEIMU

TriTrypDb:

LmxM.24.1800

Length:

106


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005930	axoneme	2	1
GO:0035869	ciliary transition zone	2	1
GO:0110165	cellular anatomical entity	1	1

E9AX25

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AX25


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	52	54	PF00675	0.639
CLV_PCSK_SKI1_1	101	105	PF00082	0.678
CLV_PCSK_SKI1_1	12	16	PF00082	0.500
DOC_USP7_MATH_1	23	27	PF00917	0.608
DOC_USP7_UBL2_3	50	54	PF12436	0.602
LIG_14-3-3_CanoR_1	10	18	PF00244	0.511
LIG_EVH1_1	83	87	PF00568	0.632
LIG_FHA_1	6	12	PF00498	0.503
LIG_LIR_Gen_1	42	51	PF02991	0.514
LIG_LIR_Gen_1	72	83	PF02991	0.556
LIG_LIR_Nem_3	13	18	PF02991	0.497
LIG_LIR_Nem_3	42	46	PF02991	0.495
LIG_LIR_Nem_3	72	78	PF02991	0.533
LIG_SH2_STAT5	75	78	PF00017	0.481
LIG_SH3_3	81	87	PF00018	0.582
MOD_GSK3_1	1	8	PF00069	0.587
MOD_GSK3_1	10	17	PF00069	0.496
MOD_PIKK_1	1	7	PF00454	0.593
TRG_ENDOCYTIC_2	75	78	PF00928	0.481


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBB6	Leptomonas seymouri	92%	100%
A0A0S4J366	Bodo saltans	59%	100%
A0A1X0NVT9	Trypanosomatidae	70%	98%
A0A3R7M555	Trypanosoma rangeli	67%	100%
A0A3S7WYM0	Leishmania donovani	97%	100%
A4HDP1	Leishmania braziliensis	96%	100%
C9ZWC2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	67%	100%
E9AH87	Leishmania infantum	97%	100%
Q4QAF1	Leishmania major	98%	100%