DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

DNA helicase

Gene product:

ATP-dependent DEAD/H DNA helicase recQ, putative

Species:

Leishmania mexicana

UniProt:

E9AWZ8_LEIMU

TriTrypDb:

LmxM.24.1530

Length:

1687

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005694	chromosome	5	1
GO:0005737	cytoplasm	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9AWZ8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	8
GO:0006259	DNA metabolic process	4	8
GO:0006310	DNA recombination	5	8
GO:0006725	cellular aromatic compound metabolic process	3	8
GO:0006807	nitrogen compound metabolic process	2	8
GO:0008152	metabolic process	1	8
GO:0009987	cellular process	1	8
GO:0034641	cellular nitrogen compound metabolic process	3	8
GO:0043170	macromolecule metabolic process	3	8
GO:0044237	cellular metabolic process	2	8
GO:0044238	primary metabolic process	2	8
GO:0044260	obsolete cellular macromolecule metabolic process	3	8
GO:0046483	heterocycle metabolic process	3	8
GO:0071704	organic substance metabolic process	2	8
GO:0090304	nucleic acid metabolic process	4	8
GO:1901360	organic cyclic compound metabolic process	3	8
GO:0000724	double-strand break repair via homologous recombination	7	1
GO:0000725	recombinational repair	6	1
GO:0006268	DNA unwinding involved in DNA replication	9	1
GO:0006281	DNA repair	5	1
GO:0006302	double-strand break repair	6	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0006996	organelle organization	4	1
GO:0016043	cellular component organization	3	1
GO:0032392	DNA geometric change	7	1
GO:0032508	DNA duplex unwinding	8	1
GO:0033554	cellular response to stress	3	1
GO:0050896	response to stimulus	1	1
GO:0051276	chromosome organization	5	1
GO:0051716	cellular response to stimulus	2	1
GO:0071103	DNA conformation change	6	1
GO:0071840	cellular component organization or biogenesis	2	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	8
GO:0003676	nucleic acid binding	3	8
GO:0003824	catalytic activity	1	8
GO:0004386	helicase activity	2	8
GO:0005488	binding	1	8
GO:0005524	ATP binding	5	8
GO:0016787	hydrolase activity	2	8
GO:0017076	purine nucleotide binding	4	8
GO:0030554	adenyl nucleotide binding	5	8
GO:0032553	ribonucleotide binding	3	8
GO:0032555	purine ribonucleotide binding	4	8
GO:0032559	adenyl ribonucleotide binding	5	8
GO:0035639	purine ribonucleoside triphosphate binding	4	8
GO:0036094	small molecule binding	2	8
GO:0043167	ion binding	2	8
GO:0043168	anion binding	3	8
GO:0097159	organic cyclic compound binding	2	8
GO:0097367	carbohydrate derivative binding	2	8
GO:0140640	catalytic activity, acting on a nucleic acid	2	8
GO:0140657	ATP-dependent activity	1	8
GO:1901265	nucleoside phosphate binding	3	8
GO:1901363	heterocyclic compound binding	2	8
GO:0003678	DNA helicase activity	3	1
GO:0008094	ATP-dependent activity, acting on DNA	2	1
GO:0009378	four-way junction helicase activity	4	1
GO:0043138	3'-5' DNA helicase activity	4	1
GO:0140097	catalytic activity, acting on DNA	3	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	177	181	PF00656	0.418
CLV_C14_Caspase3-7	778	782	PF00656	0.416
CLV_C14_Caspase3-7	826	830	PF00656	0.560
CLV_C14_Caspase3-7	897	901	PF00656	0.682
CLV_C14_Caspase3-7	996	1000	PF00656	0.734
CLV_MEL_PAP_1	42	48	PF00089	0.299
CLV_MEL_PAP_1	489	495	PF00089	0.462
CLV_NRD_NRD_1	1242	1244	PF00675	0.603
CLV_NRD_NRD_1	210	212	PF00675	0.592
CLV_NRD_NRD_1	261	263	PF00675	0.397
CLV_NRD_NRD_1	353	355	PF00675	0.280
CLV_NRD_NRD_1	418	420	PF00675	0.289
CLV_NRD_NRD_1	505	507	PF00675	0.313
CLV_NRD_NRD_1	518	520	PF00675	0.258
CLV_NRD_NRD_1	638	640	PF00675	0.294
CLV_NRD_NRD_1	880	882	PF00675	0.691
CLV_NRD_NRD_1	889	891	PF00675	0.529
CLV_NRD_NRD_1	992	994	PF00675	0.646
CLV_PCSK_FUR_1	1240	1244	PF00082	0.655
CLV_PCSK_KEX2_1	1096	1098	PF00082	0.323
CLV_PCSK_KEX2_1	1242	1244	PF00082	0.603
CLV_PCSK_KEX2_1	261	263	PF00082	0.397
CLV_PCSK_KEX2_1	353	355	PF00082	0.280
CLV_PCSK_KEX2_1	425	427	PF00082	0.384
CLV_PCSK_KEX2_1	518	520	PF00082	0.323
CLV_PCSK_KEX2_1	637	639	PF00082	0.293
CLV_PCSK_KEX2_1	880	882	PF00082	0.689
CLV_PCSK_KEX2_1	889	891	PF00082	0.527
CLV_PCSK_KEX2_1	994	996	PF00082	0.637
CLV_PCSK_PC1ET2_1	1096	1098	PF00082	0.323
CLV_PCSK_PC1ET2_1	425	427	PF00082	0.364
CLV_PCSK_PC1ET2_1	880	882	PF00082	0.709
CLV_PCSK_PC1ET2_1	994	996	PF00082	0.637
CLV_PCSK_SKI1_1	1034	1038	PF00082	0.493
CLV_PCSK_SKI1_1	1129	1133	PF00082	0.552
CLV_PCSK_SKI1_1	1198	1202	PF00082	0.691
CLV_PCSK_SKI1_1	1243	1247	PF00082	0.590
CLV_PCSK_SKI1_1	1641	1645	PF00082	0.601
CLV_PCSK_SKI1_1	230	234	PF00082	0.541
CLV_PCSK_SKI1_1	265	269	PF00082	0.423
CLV_PCSK_SKI1_1	288	292	PF00082	0.293
CLV_PCSK_SKI1_1	354	358	PF00082	0.280
CLV_PCSK_SKI1_1	393	397	PF00082	0.280
CLV_PCSK_SKI1_1	519	523	PF00082	0.323
CLV_PCSK_SKI1_1	760	764	PF00082	0.438
CLV_PCSK_SKI1_1	765	769	PF00082	0.400
CLV_PCSK_SKI1_1	805	809	PF00082	0.528
CLV_PCSK_SKI1_1	812	816	PF00082	0.519
CLV_PCSK_SKI1_1	819	823	PF00082	0.546
CLV_PCSK_SKI1_1	893	897	PF00082	0.669
DEG_APCC_DBOX_1	14	22	PF00400	0.610
DEG_APCC_DBOX_1	541	549	PF00400	0.480
DEG_APCC_DBOX_1	616	624	PF00400	0.523
DEG_APCC_DBOX_1	764	772	PF00400	0.457
DEG_Nend_UBRbox_1	1	4	PF02207	0.426
DEG_SCF_FBW7_1	60	65	PF00400	0.612
DEG_SPOP_SBC_1	918	922	PF00917	0.425
DOC_CKS1_1	1204	1209	PF01111	0.565
DOC_CKS1_1	1357	1362	PF01111	0.612
DOC_CKS1_1	1561	1566	PF01111	0.601
DOC_CKS1_1	371	376	PF01111	0.487
DOC_CKS1_1	429	434	PF01111	0.523
DOC_CKS1_1	934	939	PF01111	0.605
DOC_CKS1_1	943	948	PF01111	0.664
DOC_CYCLIN_RxL_1	1029	1040	PF00134	0.524
DOC_CYCLIN_RxL_1	351	359	PF00134	0.523
DOC_CYCLIN_RxL_1	447	456	PF00134	0.401
DOC_CYCLIN_RxL_1	757	766	PF00134	0.501
DOC_CYCLIN_yCln2_LP_2	1201	1207	PF00134	0.619
DOC_MAPK_gen_1	1104	1114	PF00069	0.547
DOC_MAPK_gen_1	477	484	PF00069	0.487
DOC_MAPK_gen_1	539	547	PF00069	0.523
DOC_MAPK_MEF2A_6	1266	1274	PF00069	0.662
DOC_MAPK_MEF2A_6	235	243	PF00069	0.568
DOC_MAPK_MEF2A_6	845	853	PF00069	0.539
DOC_PP2B_LxvP_1	1073	1076	PF13499	0.523
DOC_PP2B_LxvP_1	1378	1381	PF13499	0.759
DOC_PP2B_LxvP_1	183	186	PF13499	0.480
DOC_PP4_FxxP_1	1346	1349	PF00568	0.670
DOC_PP4_FxxP_1	1351	1354	PF00568	0.615
DOC_SPAK_OSR1_1	398	402	PF12202	0.480
DOC_USP7_MATH_1	1144	1148	PF00917	0.610
DOC_USP7_MATH_1	1169	1173	PF00917	0.466
DOC_USP7_MATH_1	1210	1214	PF00917	0.660
DOC_USP7_MATH_1	1254	1258	PF00917	0.486
DOC_USP7_MATH_1	1315	1319	PF00917	0.411
DOC_USP7_MATH_1	1333	1337	PF00917	0.494
DOC_USP7_MATH_1	1364	1368	PF00917	0.687
DOC_USP7_MATH_1	1381	1385	PF00917	0.578
DOC_USP7_MATH_1	1401	1405	PF00917	0.419
DOC_USP7_MATH_1	1433	1437	PF00917	0.726
DOC_USP7_MATH_1	1461	1465	PF00917	0.605
DOC_USP7_MATH_1	1569	1573	PF00917	0.716
DOC_USP7_MATH_1	1620	1624	PF00917	0.645
DOC_USP7_MATH_1	1632	1636	PF00917	0.550
DOC_USP7_MATH_1	188	192	PF00917	0.543
DOC_USP7_MATH_1	203	207	PF00917	0.628
DOC_USP7_MATH_1	352	356	PF00917	0.528
DOC_USP7_MATH_1	675	679	PF00917	0.557
DOC_USP7_MATH_1	718	722	PF00917	0.318
DOC_USP7_MATH_1	823	827	PF00917	0.472
DOC_USP7_MATH_1	834	838	PF00917	0.586
DOC_USP7_MATH_1	899	903	PF00917	0.746
DOC_USP7_MATH_1	909	913	PF00917	0.639
DOC_USP7_MATH_1	935	939	PF00917	0.515
DOC_USP7_MATH_1	98	102	PF00917	0.344
DOC_USP7_MATH_2	749	755	PF00917	0.476
DOC_USP7_UBL2_3	1092	1096	PF12436	0.480
DOC_USP7_UBL2_3	753	757	PF12436	0.600
DOC_USP7_UBL2_3	880	884	PF12436	0.722
DOC_WW_Pin1_4	1203	1208	PF00397	0.554
DOC_WW_Pin1_4	1217	1222	PF00397	0.589
DOC_WW_Pin1_4	1266	1271	PF00397	0.657
DOC_WW_Pin1_4	1316	1321	PF00397	0.440
DOC_WW_Pin1_4	132	137	PF00397	0.626
DOC_WW_Pin1_4	1356	1361	PF00397	0.692
DOC_WW_Pin1_4	1371	1376	PF00397	0.488
DOC_WW_Pin1_4	1391	1396	PF00397	0.501
DOC_WW_Pin1_4	1469	1474	PF00397	0.643
DOC_WW_Pin1_4	1560	1565	PF00397	0.616
DOC_WW_Pin1_4	1649	1654	PF00397	0.690
DOC_WW_Pin1_4	318	323	PF00397	0.480
DOC_WW_Pin1_4	370	375	PF00397	0.490
DOC_WW_Pin1_4	428	433	PF00397	0.523
DOC_WW_Pin1_4	491	496	PF00397	0.455
DOC_WW_Pin1_4	58	63	PF00397	0.621
DOC_WW_Pin1_4	745	750	PF00397	0.622
DOC_WW_Pin1_4	76	81	PF00397	0.678
DOC_WW_Pin1_4	794	799	PF00397	0.529
DOC_WW_Pin1_4	933	938	PF00397	0.566
DOC_WW_Pin1_4	942	947	PF00397	0.567
LIG_14-3-3_CanoR_1	1043	1049	PF00244	0.564
LIG_14-3-3_CanoR_1	1068	1076	PF00244	0.488
LIG_14-3-3_CanoR_1	1143	1153	PF00244	0.629
LIG_14-3-3_CanoR_1	1167	1177	PF00244	0.607
LIG_14-3-3_CanoR_1	1211	1221	PF00244	0.660
LIG_14-3-3_CanoR_1	1240	1246	PF00244	0.612
LIG_14-3-3_CanoR_1	1266	1270	PF00244	0.600
LIG_14-3-3_CanoR_1	1271	1275	PF00244	0.566
LIG_14-3-3_CanoR_1	1582	1586	PF00244	0.678
LIG_14-3-3_CanoR_1	211	217	PF00244	0.566
LIG_14-3-3_CanoR_1	253	263	PF00244	0.459
LIG_14-3-3_CanoR_1	353	357	PF00244	0.500
LIG_14-3-3_CanoR_1	419	424	PF00244	0.523
LIG_14-3-3_CanoR_1	617	627	PF00244	0.533
LIG_14-3-3_CanoR_1	729	739	PF00244	0.442
LIG_14-3-3_CanoR_1	81	86	PF00244	0.488
LIG_14-3-3_CanoR_1	812	817	PF00244	0.570
LIG_14-3-3_CanoR_1	867	876	PF00244	0.737
LIG_Actin_WH2_2	441	457	PF00022	0.547
LIG_Actin_WH2_2	699	717	PF00022	0.396
LIG_APCC_ABBA_1	773	778	PF00400	0.412
LIG_APCC_ABBAyCdc20_2	353	359	PF00400	0.480
LIG_BIR_III_2	1537	1541	PF00653	0.604
LIG_BRCT_BRCA1_1	1634	1638	PF00533	0.601
LIG_BRCT_BRCA1_1	379	383	PF00533	0.480
LIG_Clathr_ClatBox_1	1084	1088	PF01394	0.564
LIG_Clathr_ClatBox_1	18	22	PF01394	0.631
LIG_CtBP_PxDLS_1	66	70	PF00389	0.584
LIG_deltaCOP1_diTrp_1	359	362	PF00928	0.393
LIG_EH1_1	363	371	PF00400	0.564
LIG_eIF4E_1	304	310	PF01652	0.480
LIG_EVH1_1	1351	1355	PF00568	0.611
LIG_FHA_1	1068	1074	PF00498	0.523
LIG_FHA_1	1317	1323	PF00498	0.546
LIG_FHA_1	1429	1435	PF00498	0.604
LIG_FHA_1	1594	1600	PF00498	0.475
LIG_FHA_1	234	240	PF00498	0.569
LIG_FHA_1	315	321	PF00498	0.480
LIG_FHA_1	439	445	PF00498	0.480
LIG_FHA_1	449	455	PF00498	0.343
LIG_FHA_1	813	819	PF00498	0.536
LIG_FHA_2	1232	1238	PF00498	0.711
LIG_FHA_2	1679	1685	PF00498	0.681
LIG_FHA_2	437	443	PF00498	0.480
LIG_FHA_2	539	545	PF00498	0.480
LIG_FHA_2	597	603	PF00498	0.573
LIG_FHA_2	628	634	PF00498	0.454
LIG_FHA_2	694	700	PF00498	0.489
LIG_FHA_2	746	752	PF00498	0.625
LIG_FHA_2	764	770	PF00498	0.519
LIG_FHA_2	841	847	PF00498	0.519
LIG_FHA_2	901	907	PF00498	0.656
LIG_FHA_2	975	981	PF00498	0.702
LIG_FHA_2	994	1000	PF00498	0.740
LIG_Integrin_RGD_1	997	999	PF01839	0.736
LIG_LIR_Apic_2	301	307	PF02991	0.480
LIG_LIR_Apic_2	368	374	PF02991	0.480
LIG_LIR_Gen_1	1057	1066	PF02991	0.523
LIG_LIR_Gen_1	272	283	PF02991	0.464
LIG_LIR_Gen_1	289	295	PF02991	0.397
LIG_LIR_Gen_1	329	340	PF02991	0.523
LIG_LIR_Gen_1	43	54	PF02991	0.513
LIG_LIR_Gen_1	708	718	PF02991	0.476
LIG_LIR_Nem_3	215	219	PF02991	0.572
LIG_LIR_Nem_3	272	278	PF02991	0.484
LIG_LIR_Nem_3	289	294	PF02991	0.397
LIG_LIR_Nem_3	329	335	PF02991	0.523
LIG_LIR_Nem_3	359	365	PF02991	0.393
LIG_LIR_Nem_3	417	421	PF02991	0.480
LIG_LIR_Nem_3	43	49	PF02991	0.434
LIG_LIR_Nem_3	708	713	PF02991	0.393
LIG_LIR_Nem_3	829	835	PF02991	0.598
LIG_MYND_1	1284	1288	PF01753	0.686
LIG_MYND_1	1377	1381	PF01753	0.657
LIG_MYND_1	307	311	PF01753	0.480
LIG_MYND_1	667	671	PF01753	0.564
LIG_NRBOX	1032	1038	PF00104	0.484
LIG_PCNA_yPIPBox_3	1032	1045	PF02747	0.513
LIG_Pex14_1	410	414	PF04695	0.493
LIG_Pex14_2	1246	1250	PF04695	0.419
LIG_Pex14_2	460	464	PF04695	0.340
LIG_PTAP_UEV_1	1394	1399	PF05743	0.474
LIG_Rb_pABgroove_1	848	856	PF01858	0.553
LIG_SH2_CRK	304	308	PF00017	0.480
LIG_SH2_CRK	332	336	PF00017	0.488
LIG_SH2_CRK	418	422	PF00017	0.480
LIG_SH2_CRK	710	714	PF00017	0.451
LIG_SH2_NCK_1	332	336	PF00017	0.488
LIG_SH2_NCK_1	93	97	PF00017	0.489
LIG_SH2_PTP2	1111	1114	PF00017	0.489
LIG_SH2_PTP2	371	374	PF00017	0.480
LIG_SH2_SRC	1111	1114	PF00017	0.431
LIG_SH2_SRC	579	582	PF00017	0.507
LIG_SH2_SRC	710	713	PF00017	0.451
LIG_SH2_STAP1	1594	1598	PF00017	0.528
LIG_SH2_STAP1	219	223	PF00017	0.547
LIG_SH2_STAP1	332	336	PF00017	0.480
LIG_SH2_STAP1	710	714	PF00017	0.451
LIG_SH2_STAP1	93	97	PF00017	0.394
LIG_SH2_STAT3	219	222	PF00017	0.550
LIG_SH2_STAT3	471	474	PF00017	0.453
LIG_SH2_STAT5	1111	1114	PF00017	0.431
LIG_SH2_STAT5	118	121	PF00017	0.616
LIG_SH2_STAT5	1551	1554	PF00017	0.625
LIG_SH2_STAT5	371	374	PF00017	0.480
LIG_SH2_STAT5	376	379	PF00017	0.480
LIG_SH2_STAT5	502	505	PF00017	0.480
LIG_SH2_STAT5	565	568	PF00017	0.527
LIG_SH2_STAT5	629	632	PF00017	0.480
LIG_SH2_STAT5	894	897	PF00017	0.642
LIG_SH3_1	1417	1423	PF00018	0.648
LIG_SH3_1	426	432	PF00018	0.507
LIG_SH3_2	1204	1209	PF14604	0.584
LIG_SH3_2	138	143	PF14604	0.491
LIG_SH3_3	101	107	PF00018	0.369
LIG_SH3_3	1131	1137	PF00018	0.467
LIG_SH3_3	1201	1207	PF00018	0.583
LIG_SH3_3	1226	1232	PF00018	0.668
LIG_SH3_3	1281	1287	PF00018	0.630
LIG_SH3_3	130	136	PF00018	0.642
LIG_SH3_3	1335	1341	PF00018	0.682
LIG_SH3_3	1346	1352	PF00018	0.604
LIG_SH3_3	1392	1398	PF00018	0.587
LIG_SH3_3	1417	1423	PF00018	0.648
LIG_SH3_3	152	158	PF00018	0.547
LIG_SH3_3	236	242	PF00018	0.569
LIG_SH3_3	289	295	PF00018	0.480
LIG_SH3_3	316	322	PF00018	0.486
LIG_SH3_3	426	432	PF00018	0.459
LIG_SH3_3	662	668	PF00018	0.520
LIG_SH3_3	940	946	PF00018	0.675
LIG_SH3_3	985	991	PF00018	0.752
LIG_SH3_4	882	889	PF00018	0.651
LIG_Sin3_3	1403	1410	PF02671	0.466
LIG_SUMO_SIM_anti_2	1508	1516	PF11976	0.611
LIG_SUMO_SIM_anti_2	16	25	PF11976	0.588
LIG_SUMO_SIM_par_1	1083	1088	PF11976	0.564
LIG_SUMO_SIM_par_1	1198	1203	PF11976	0.612
LIG_SUMO_SIM_par_1	1259	1265	PF11976	0.422
LIG_SUMO_SIM_par_1	16	25	PF11976	0.588
LIG_SUMO_SIM_par_1	316	321	PF11976	0.480
LIG_SUMO_SIM_par_1	450	456	PF11976	0.434
LIG_SUMO_SIM_par_1	849	855	PF11976	0.549
LIG_SxIP_EBH_1	1467	1480	PF03271	0.462
LIG_TRAF2_1	875	878	PF00917	0.602
LIG_TRAF2_1	912	915	PF00917	0.703
LIG_TRFH_1	291	295	PF08558	0.480
LIG_UBA3_1	1084	1092	PF00899	0.606
LIG_WRC_WIRS_1	1245	1250	PF05994	0.597
LIG_WRC_WIRS_1	923	928	PF05994	0.623
LIG_WW_2	1284	1287	PF00397	0.688
LIG_WW_2	667	670	PF00397	0.518
LIG_WW_3	990	994	PF00397	0.762
MOD_CDK_SPK_2	1266	1271	PF00069	0.593
MOD_CDK_SPK_2	76	81	PF00069	0.522
MOD_CDK_SPxK_1	1203	1209	PF00069	0.569
MOD_CDK_SPxK_1	1217	1223	PF00069	0.543
MOD_CDK_SPxK_1	942	948	PF00069	0.656
MOD_CDK_SPxxK_3	1649	1656	PF00069	0.509
MOD_CK1_1	1213	1219	PF00069	0.621
MOD_CK1_1	1249	1255	PF00069	0.642
MOD_CK1_1	1262	1268	PF00069	0.527
MOD_CK1_1	1371	1377	PF00069	0.637
MOD_CK1_1	1396	1402	PF00069	0.658
MOD_CK1_1	1453	1459	PF00069	0.693
MOD_CK1_1	1581	1587	PF00069	0.751
MOD_CK1_1	1623	1629	PF00069	0.649
MOD_CK1_1	191	197	PF00069	0.592
MOD_CK1_1	199	205	PF00069	0.578
MOD_CK1_1	206	212	PF00069	0.530
MOD_CK1_1	494	500	PF00069	0.394
MOD_CK1_1	598	604	PF00069	0.383
MOD_CK1_1	619	625	PF00069	0.490
MOD_CK1_1	673	679	PF00069	0.547
MOD_CK1_1	68	74	PF00069	0.672
MOD_CK1_1	837	843	PF00069	0.542
MOD_CK1_1	917	923	PF00069	0.573
MOD_CK1_1	933	939	PF00069	0.460
MOD_CK1_1	941	947	PF00069	0.577
MOD_CK1_1	954	960	PF00069	0.661
MOD_CK1_1	965	971	PF00069	0.571
MOD_CK1_1	976	982	PF00069	0.626
MOD_CK2_1	1118	1124	PF00069	0.440
MOD_CK2_1	1144	1150	PF00069	0.579
MOD_CK2_1	1627	1633	PF00069	0.626
MOD_CK2_1	1634	1640	PF00069	0.552
MOD_CK2_1	1644	1650	PF00069	0.592
MOD_CK2_1	198	204	PF00069	0.626
MOD_CK2_1	529	535	PF00069	0.496
MOD_CK2_1	538	544	PF00069	0.459
MOD_CK2_1	693	699	PF00069	0.502
MOD_CK2_1	728	734	PF00069	0.453
MOD_CK2_1	745	751	PF00069	0.623
MOD_CK2_1	763	769	PF00069	0.526
MOD_CK2_1	908	914	PF00069	0.672
MOD_CK2_1	974	980	PF00069	0.700
MOD_Cter_Amidation	887	890	PF01082	0.692
MOD_DYRK1A_RPxSP_1	1266	1270	PF00069	0.656
MOD_GlcNHglycan	101	104	PF01048	0.671
MOD_GlcNHglycan	111	114	PF01048	0.495
MOD_GlcNHglycan	1146	1149	PF01048	0.510
MOD_GlcNHglycan	1158	1164	PF01048	0.591
MOD_GlcNHglycan	1171	1174	PF01048	0.529
MOD_GlcNHglycan	1215	1218	PF01048	0.728
MOD_GlcNHglycan	1226	1229	PF01048	0.564
MOD_GlcNHglycan	1256	1259	PF01048	0.416
MOD_GlcNHglycan	1346	1349	PF01048	0.594
MOD_GlcNHglycan	1366	1369	PF01048	0.517
MOD_GlcNHglycan	1371	1374	PF01048	0.691
MOD_GlcNHglycan	1395	1398	PF01048	0.586
MOD_GlcNHglycan	1401	1404	PF01048	0.554
MOD_GlcNHglycan	1452	1455	PF01048	0.670
MOD_GlcNHglycan	146	149	PF01048	0.700
MOD_GlcNHglycan	1495	1498	PF01048	0.685
MOD_GlcNHglycan	1509	1512	PF01048	0.438
MOD_GlcNHglycan	1565	1568	PF01048	0.789
MOD_GlcNHglycan	1569	1572	PF01048	0.692
MOD_GlcNHglycan	1622	1625	PF01048	0.666
MOD_GlcNHglycan	193	196	PF01048	0.464
MOD_GlcNHglycan	201	204	PF01048	0.526
MOD_GlcNHglycan	205	208	PF01048	0.492
MOD_GlcNHglycan	581	584	PF01048	0.290
MOD_GlcNHglycan	672	675	PF01048	0.328
MOD_GlcNHglycan	677	680	PF01048	0.312
MOD_GlcNHglycan	753	756	PF01048	0.461
MOD_GlcNHglycan	836	839	PF01048	0.536
MOD_GlcNHglycan	871	874	PF01048	0.649
MOD_GlcNHglycan	914	919	PF01048	0.672
MOD_GlcNHglycan	94	97	PF01048	0.581
MOD_GSK3_1	1213	1220	PF00069	0.649
MOD_GSK3_1	1244	1251	PF00069	0.605
MOD_GSK3_1	1262	1269	PF00069	0.411
MOD_GSK3_1	128	135	PF00069	0.698
MOD_GSK3_1	1304	1311	PF00069	0.578
MOD_GSK3_1	1364	1371	PF00069	0.548
MOD_GSK3_1	1424	1431	PF00069	0.684
MOD_GSK3_1	1442	1449	PF00069	0.666
MOD_GSK3_1	1469	1476	PF00069	0.641
MOD_GSK3_1	1518	1525	PF00069	0.601
MOD_GSK3_1	1563	1570	PF00069	0.682
MOD_GSK3_1	1593	1600	PF00069	0.650
MOD_GSK3_1	1622	1629	PF00069	0.624
MOD_GSK3_1	1632	1639	PF00069	0.578
MOD_GSK3_1	191	198	PF00069	0.613
MOD_GSK3_1	199	206	PF00069	0.548
MOD_GSK3_1	314	321	PF00069	0.482
MOD_GSK3_1	434	441	PF00069	0.499
MOD_GSK3_1	521	528	PF00069	0.530
MOD_GSK3_1	58	65	PF00069	0.640
MOD_GSK3_1	67	74	PF00069	0.636
MOD_GSK3_1	76	83	PF00069	0.424
MOD_GSK3_1	914	921	PF00069	0.541
MOD_GSK3_1	929	936	PF00069	0.599
MOD_GSK3_1	938	945	PF00069	0.567
MOD_GSK3_1	951	958	PF00069	0.747
MOD_GSK3_1	961	968	PF00069	0.597
MOD_N-GLC_1	1144	1149	PF02516	0.614
MOD_N-GLC_1	1382	1387	PF02516	0.621
MOD_N-GLC_1	173	178	PF02516	0.459
MOD_N-GLC_1	191	196	PF02516	0.375
MOD_N-GLC_2	282	284	PF02516	0.280
MOD_NEK2_1	1044	1049	PF00069	0.523
MOD_NEK2_1	1069	1074	PF00069	0.480
MOD_NEK2_1	1168	1173	PF00069	0.468
MOD_NEK2_1	1246	1251	PF00069	0.593
MOD_NEK2_1	128	133	PF00069	0.742
MOD_NEK2_1	1446	1451	PF00069	0.656
MOD_NEK2_1	1468	1473	PF00069	0.641
MOD_NEK2_1	1481	1486	PF00069	0.695
MOD_NEK2_1	1627	1632	PF00069	0.672
MOD_NEK2_1	1643	1648	PF00069	0.539
MOD_NEK2_1	233	238	PF00069	0.530
MOD_NEK2_1	342	347	PF00069	0.480
MOD_NEK2_1	383	388	PF00069	0.480
MOD_NEK2_1	436	441	PF00069	0.480
MOD_NEK2_1	460	465	PF00069	0.340
MOD_NEK2_1	469	474	PF00069	0.387
MOD_NEK2_1	52	57	PF00069	0.557
MOD_NEK2_1	596	601	PF00069	0.579
MOD_NEK2_1	627	632	PF00069	0.532
MOD_NEK2_1	653	658	PF00069	0.480
MOD_NEK2_1	72	77	PF00069	0.526
MOD_NEK2_1	763	768	PF00069	0.530
MOD_NEK2_1	919	924	PF00069	0.721
MOD_NEK2_2	352	357	PF00069	0.523
MOD_PIKK_1	1047	1053	PF00454	0.564
MOD_PIKK_1	1428	1434	PF00454	0.669
MOD_PIKK_1	1473	1479	PF00454	0.643
MOD_PIKK_1	1518	1524	PF00454	0.625
MOD_PIKK_1	405	411	PF00454	0.480
MOD_PIKK_1	653	659	PF00454	0.523
MOD_PIKK_1	678	684	PF00454	0.523
MOD_PIKK_1	967	973	PF00454	0.720
MOD_PK_1	419	425	PF00069	0.523
MOD_PK_1	779	785	PF00069	0.411
MOD_PK_1	81	87	PF00069	0.495
MOD_PKA_1	419	425	PF00069	0.523
MOD_PKA_1	889	895	PF00069	0.532
MOD_PKA_1	993	999	PF00069	0.628
MOD_PKA_2	1067	1073	PF00069	0.488
MOD_PKA_2	1169	1175	PF00069	0.369
MOD_PKA_2	1210	1216	PF00069	0.716
MOD_PKA_2	1241	1247	PF00069	0.558
MOD_PKA_2	1265	1271	PF00069	0.623
MOD_PKA_2	1450	1456	PF00069	0.662
MOD_PKA_2	1481	1487	PF00069	0.751
MOD_PKA_2	1581	1587	PF00069	0.576
MOD_PKA_2	352	358	PF00069	0.523
MOD_PKA_2	44	50	PF00069	0.434
MOD_PKA_2	538	544	PF00069	0.514
MOD_PKA_2	616	622	PF00069	0.532
MOD_PKA_2	728	734	PF00069	0.416
MOD_PKA_2	80	86	PF00069	0.454
MOD_PKA_2	823	829	PF00069	0.490
MOD_PKA_2	866	872	PF00069	0.670
MOD_PKA_2	889	895	PF00069	0.704
MOD_PKA_2	962	968	PF00069	0.688
MOD_Plk_1	1632	1638	PF00069	0.571
MOD_Plk_1	763	769	PF00069	0.526
MOD_Plk_1	828	834	PF00069	0.460
MOD_Plk_1	914	920	PF00069	0.566
MOD_Plk_1	929	935	PF00069	0.504
MOD_Plk_2-3	1118	1124	PF00069	0.500
MOD_Plk_2-3	1545	1551	PF00069	0.573
MOD_Plk_2-3	1634	1640	PF00069	0.573
MOD_Plk_2-3	1678	1684	PF00069	0.683
MOD_Plk_2-3	693	699	PF00069	0.494
MOD_Plk_2-3	900	906	PF00069	0.623
MOD_Plk_4	1044	1050	PF00069	0.500
MOD_Plk_4	1062	1068	PF00069	0.523
MOD_Plk_4	1130	1136	PF00069	0.465
MOD_Plk_4	1425	1431	PF00069	0.675
MOD_Plk_4	314	320	PF00069	0.480
MOD_Plk_4	365	371	PF00069	0.480
MOD_Plk_4	419	425	PF00069	0.523
MOD_Plk_4	52	58	PF00069	0.542
MOD_Plk_4	521	527	PF00069	0.480
MOD_Plk_4	72	78	PF00069	0.537
MOD_Plk_4	81	87	PF00069	0.549
MOD_Plk_4	922	928	PF00069	0.587
MOD_ProDKin_1	1203	1209	PF00069	0.552
MOD_ProDKin_1	1217	1223	PF00069	0.586
MOD_ProDKin_1	1266	1272	PF00069	0.658
MOD_ProDKin_1	1316	1322	PF00069	0.441
MOD_ProDKin_1	132	138	PF00069	0.626
MOD_ProDKin_1	1356	1362	PF00069	0.697
MOD_ProDKin_1	1371	1377	PF00069	0.493
MOD_ProDKin_1	1391	1397	PF00069	0.495
MOD_ProDKin_1	1469	1475	PF00069	0.642
MOD_ProDKin_1	1560	1566	PF00069	0.623
MOD_ProDKin_1	1649	1655	PF00069	0.692
MOD_ProDKin_1	318	324	PF00069	0.480
MOD_ProDKin_1	370	376	PF00069	0.490
MOD_ProDKin_1	428	434	PF00069	0.523
MOD_ProDKin_1	491	497	PF00069	0.455
MOD_ProDKin_1	58	64	PF00069	0.624
MOD_ProDKin_1	745	751	PF00069	0.623
MOD_ProDKin_1	76	82	PF00069	0.672
MOD_ProDKin_1	794	800	PF00069	0.536
MOD_ProDKin_1	933	939	PF00069	0.572
MOD_ProDKin_1	942	948	PF00069	0.569
MOD_SUMO_rev_2	1121	1131	PF00179	0.549
TRG_DiLeu_BaEn_1	1040	1045	PF01217	0.480
TRG_DiLeu_BaEn_1	1463	1468	PF01217	0.618
TRG_DiLeu_BaLyEn_6	1374	1379	PF01217	0.648
TRG_DiLeu_BaLyEn_6	319	324	PF01217	0.523
TRG_DiLeu_BaLyEn_6	605	610	PF01217	0.523
TRG_ENDOCYTIC_2	1058	1061	PF00928	0.480
TRG_ENDOCYTIC_2	1106	1109	PF00928	0.348
TRG_ENDOCYTIC_2	1111	1114	PF00928	0.371
TRG_ENDOCYTIC_2	332	335	PF00928	0.523
TRG_ENDOCYTIC_2	418	421	PF00928	0.480
TRG_ENDOCYTIC_2	710	713	PF00928	0.451
TRG_ER_diArg_1	1135	1138	PF00400	0.510
TRG_ER_diArg_1	1239	1242	PF00400	0.601
TRG_ER_diArg_1	260	262	PF00400	0.406
TRG_ER_diArg_1	517	519	PF00400	0.523
TRG_ER_diArg_1	637	639	PF00400	0.492
TRG_ER_diArg_1	742	745	PF00400	0.510
TRG_ER_diArg_1	816	819	PF00400	0.527
TRG_ER_diArg_1	992	995	PF00400	0.700
TRG_NES_CRM1_1	1545	1558	PF08389	0.546
TRG_NES_CRM1_1	259	272	PF08389	0.437
TRG_NES_CRM1_1	546	562	PF08389	0.480
TRG_NLS_MonoCore_2	880	885	PF00514	0.626
TRG_NLS_MonoExtC_3	879	884	PF00514	0.676
TRG_NLS_MonoExtC_3	885	890	PF00514	0.645
TRG_NLS_MonoExtC_3	992	997	PF00514	0.697
TRG_NLS_MonoExtN_4	879	885	PF00514	0.670
TRG_NLS_MonoExtN_4	991	998	PF00514	0.637
TRG_Pf-PMV_PEXEL_1	1641	1645	PF00026	0.618
TRG_Pf-PMV_PEXEL_1	354	358	PF00026	0.280
TRG_Pf-PMV_PEXEL_1	6	10	PF00026	0.611
TRG_Pf-PMV_PEXEL_1	765	769	PF00026	0.406

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P880	Leptomonas seymouri	53%	85%
A0A3Q8IC54	Leishmania donovani	89%	100%
A4HDI8	Leishmania braziliensis	76%	100%
A4I0Z1	Leishmania infantum	89%	87%
C9ZWF4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
Q4QAH8	Leishmania major	89%	100%