Crossover junction endonuclease MUS81

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ERCC4 domain containing protein, putative

Species:

Leishmania mexicana

UniProt:

E9AWZ7_LEIMU

TriTrypDb:

LmxM.24.1520

Length:

1148

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0032991	protein-containing complex	1	1
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0048476	Holliday junction resolvase complex	5	1
GO:0110165	cellular anatomical entity	1	2
GO:0140535	intracellular protein-containing complex	2	1
GO:1902494	catalytic complex	2	1
GO:1905347	endodeoxyribonuclease complex	4	1
GO:1905348	endonuclease complex	3	1

Expansion

Sequence features

E9AWZ7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AWZ7

Function

Biological processes
Term	Name	Level	Count
GO:0000737	obsolete DNA catabolic process, endonucleolytic	6	7
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006259	DNA metabolic process	4	7
GO:0006281	DNA repair	5	7
GO:0006302	double-strand break repair	6	7
GO:0006308	DNA catabolic process	5	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0006950	response to stress	2	7
GO:0006974	DNA damage response	4	7
GO:0008152	metabolic process	1	7
GO:0009056	catabolic process	2	7
GO:0009057	macromolecule catabolic process	4	7
GO:0009987	cellular process	1	7
GO:0019439	aromatic compound catabolic process	4	7
GO:0033554	cellular response to stress	3	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0034655	nucleobase-containing compound catabolic process	4	7
GO:0043170	macromolecule metabolic process	3	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044248	cellular catabolic process	3	7
GO:0044260	obsolete cellular macromolecule metabolic process	3	7
GO:0044265	obsolete cellular macromolecule catabolic process	4	7
GO:0044270	cellular nitrogen compound catabolic process	4	7
GO:0046483	heterocycle metabolic process	3	7
GO:0046700	heterocycle catabolic process	4	7
GO:0050896	response to stimulus	1	7
GO:0051716	cellular response to stimulus	2	7
GO:0071704	organic substance metabolic process	2	7
GO:0090304	nucleic acid metabolic process	4	7
GO:1901360	organic cyclic compound metabolic process	3	7
GO:1901361	organic cyclic compound catabolic process	4	7
GO:1901575	organic substance catabolic process	3	7
GO:0000075	cell cycle checkpoint signaling	4	1
GO:0000077	DNA damage checkpoint signaling	5	1
GO:0000712	resolution of meiotic recombination intermediates	4	1
GO:0000724	double-strand break repair via homologous recombination	7	1
GO:0000725	recombinational repair	6	1
GO:0000727	double-strand break repair via break-induced replication	8	1
GO:0006310	DNA recombination	5	2
GO:0007093	mitotic cell cycle checkpoint signaling	4	1
GO:0007165	signal transduction	2	1
GO:0007346	regulation of mitotic cell cycle	5	1
GO:0010564	regulation of cell cycle process	5	1
GO:0010948	negative regulation of cell cycle process	6	1
GO:0022402	cell cycle process	2	1
GO:0022414	reproductive process	1	1
GO:0031570	DNA integrity checkpoint signaling	5	1
GO:0031573	mitotic intra-S DNA damage checkpoint signaling	7	1
GO:0035556	intracellular signal transduction	3	1
GO:0042770	signal transduction in response to DNA damage	4	1
GO:0044773	mitotic DNA damage checkpoint signaling	6	1
GO:0044774	mitotic DNA integrity checkpoint signaling	5	1
GO:0045786	negative regulation of cell cycle	5	1
GO:0045930	negative regulation of mitotic cell cycle	6	1
GO:0048519	negative regulation of biological process	3	1
GO:0048523	negative regulation of cellular process	4	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051726	regulation of cell cycle	4	1
GO:0061982	meiosis I cell cycle process	3	1
GO:0065007	biological regulation	1	1
GO:1901987	regulation of cell cycle phase transition	6	1
GO:1901988	negative regulation of cell cycle phase transition	7	1
GO:1903046	meiotic cell cycle process	2	1
GO:1903047	mitotic cell cycle process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003677	DNA binding	4	7
GO:0003824	catalytic activity	1	7
GO:0004518	nuclease activity	4	7
GO:0004519	endonuclease activity	5	7
GO:0004520	DNA endonuclease activity	5	7
GO:0004536	DNA nuclease activity	4	7
GO:0005488	binding	1	7
GO:0008821	crossover junction DNA endonuclease activity	7	7
GO:0016787	hydrolase activity	2	7
GO:0016788	hydrolase activity, acting on ester bonds	3	7
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	6	7
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	6	7
GO:0097159	organic cyclic compound binding	2	7
GO:0140097	catalytic activity, acting on DNA	3	7
GO:0140640	catalytic activity, acting on a nucleic acid	2	7
GO:1901363	heterocyclic compound binding	2	7
GO:0048256	flap endonuclease activity	6	1
GO:0048257	3'-flap endonuclease activity	7	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1024	1028	PF00656	0.508
CLV_C14_Caspase3-7	281	285	PF00656	0.787
CLV_C14_Caspase3-7	299	303	PF00656	0.458
CLV_C14_Caspase3-7	311	315	PF00656	0.624
CLV_C14_Caspase3-7	526	530	PF00656	0.579
CLV_NRD_NRD_1	1112	1114	PF00675	0.574
CLV_NRD_NRD_1	115	117	PF00675	0.610
CLV_NRD_NRD_1	318	320	PF00675	0.656
CLV_NRD_NRD_1	785	787	PF00675	0.289
CLV_NRD_NRD_1	854	856	PF00675	0.338
CLV_NRD_NRD_1	874	876	PF00675	0.222
CLV_PCSK_KEX2_1	1111	1113	PF00082	0.588
CLV_PCSK_KEX2_1	115	117	PF00082	0.610
CLV_PCSK_KEX2_1	320	322	PF00082	0.666
CLV_PCSK_KEX2_1	465	467	PF00082	0.606
CLV_PCSK_KEX2_1	874	876	PF00082	0.481
CLV_PCSK_PC1ET2_1	320	322	PF00082	0.666
CLV_PCSK_PC1ET2_1	465	467	PF00082	0.606
CLV_PCSK_PC7_1	1108	1114	PF00082	0.542
CLV_PCSK_SKI1_1	1075	1079	PF00082	0.526
CLV_PCSK_SKI1_1	35	39	PF00082	0.689
CLV_PCSK_SKI1_1	460	464	PF00082	0.586
CLV_PCSK_SKI1_1	520	524	PF00082	0.534
CLV_PCSK_SKI1_1	631	635	PF00082	0.649
CLV_PCSK_SKI1_1	874	878	PF00082	0.475
DEG_APCC_DBOX_1	60	68	PF00400	0.581
DEG_SCF_FBW7_1	1053	1060	PF00400	0.358
DEG_SCF_FBW7_1	393	399	PF00400	0.740
DEG_SPOP_SBC_1	49	53	PF00917	0.558
DEG_SPOP_SBC_1	685	689	PF00917	0.676
DOC_ANK_TNKS_1	261	268	PF00023	0.683
DOC_ANK_TNKS_1	988	995	PF00023	0.635
DOC_CKS1_1	1054	1059	PF01111	0.293
DOC_CKS1_1	186	191	PF01111	0.740
DOC_CKS1_1	393	398	PF01111	0.734
DOC_CYCLIN_RxL_1	32	43	PF00134	0.693
DOC_CYCLIN_RxL_1	517	527	PF00134	0.499
DOC_CYCLIN_yCln2_LP_2	290	296	PF00134	0.691
DOC_MAPK_gen_1	1132	1138	PF00069	0.420
DOC_MAPK_gen_1	751	760	PF00069	0.534
DOC_PP1_RVXF_1	431	437	PF00149	0.516
DOC_PP1_RVXF_1	749	755	PF00149	0.618
DOC_PP1_RVXF_1	881	888	PF00149	0.441
DOC_PP2B_LxvP_1	154	157	PF13499	0.494
DOC_PP2B_LxvP_1	250	253	PF13499	0.704
DOC_PP2B_LxvP_1	290	293	PF13499	0.650
DOC_PP2B_LxvP_1	294	297	PF13499	0.655
DOC_PP2B_LxvP_1	605	608	PF13499	0.654
DOC_USP7_MATH_1	1091	1095	PF00917	0.444
DOC_USP7_MATH_1	180	184	PF00917	0.733
DOC_USP7_MATH_1	205	209	PF00917	0.742
DOC_USP7_MATH_1	278	282	PF00917	0.613
DOC_USP7_MATH_1	470	474	PF00917	0.614
DOC_USP7_MATH_1	49	53	PF00917	0.585
DOC_USP7_MATH_1	585	589	PF00917	0.565
DOC_USP7_MATH_1	608	612	PF00917	0.640
DOC_USP7_MATH_1	620	624	PF00917	0.803
DOC_USP7_MATH_1	640	644	PF00917	0.606
DOC_USP7_MATH_1	65	69	PF00917	0.601
DOC_USP7_MATH_1	674	678	PF00917	0.688
DOC_USP7_MATH_1	686	690	PF00917	0.711
DOC_USP7_MATH_1	691	695	PF00917	0.640
DOC_USP7_MATH_1	791	795	PF00917	0.332
DOC_USP7_MATH_1	832	836	PF00917	0.313
DOC_USP7_MATH_1	895	899	PF00917	0.353
DOC_USP7_MATH_1	929	933	PF00917	0.369
DOC_USP7_MATH_1	934	938	PF00917	0.330
DOC_USP7_MATH_1	945	949	PF00917	0.300
DOC_USP7_MATH_2	96	102	PF00917	0.681
DOC_WW_Pin1_4	1053	1058	PF00397	0.348
DOC_WW_Pin1_4	107	112	PF00397	0.518
DOC_WW_Pin1_4	117	122	PF00397	0.684
DOC_WW_Pin1_4	148	153	PF00397	0.604
DOC_WW_Pin1_4	156	161	PF00397	0.616
DOC_WW_Pin1_4	185	190	PF00397	0.704
DOC_WW_Pin1_4	196	201	PF00397	0.576
DOC_WW_Pin1_4	245	250	PF00397	0.569
DOC_WW_Pin1_4	265	270	PF00397	0.624
DOC_WW_Pin1_4	323	328	PF00397	0.696
DOC_WW_Pin1_4	358	363	PF00397	0.786
DOC_WW_Pin1_4	377	382	PF00397	0.570
DOC_WW_Pin1_4	389	394	PF00397	0.678
DOC_WW_Pin1_4	424	429	PF00397	0.641
DOC_WW_Pin1_4	625	630	PF00397	0.628
DOC_WW_Pin1_4	635	640	PF00397	0.656
DOC_WW_Pin1_4	700	705	PF00397	0.551
DOC_WW_Pin1_4	715	720	PF00397	0.571
DOC_WW_Pin1_4	806	811	PF00397	0.303
DOC_WW_Pin1_4	877	882	PF00397	0.332
DOC_WW_Pin1_4	88	93	PF00397	0.752
DOC_WW_Pin1_4	923	928	PF00397	0.334
DOC_WW_Pin1_4	930	935	PF00397	0.328
LIG_14-3-3_CanoR_1	1073	1082	PF00244	0.424
LIG_14-3-3_CanoR_1	1086	1095	PF00244	0.411
LIG_14-3-3_CanoR_1	1126	1135	PF00244	0.426
LIG_14-3-3_CanoR_1	115	121	PF00244	0.727
LIG_14-3-3_CanoR_1	126	130	PF00244	0.612
LIG_14-3-3_CanoR_1	433	437	PF00244	0.556
LIG_14-3-3_CanoR_1	438	447	PF00244	0.551
LIG_14-3-3_CanoR_1	480	490	PF00244	0.516
LIG_14-3-3_CanoR_1	520	525	PF00244	0.532
LIG_14-3-3_CanoR_1	657	667	PF00244	0.685
LIG_14-3-3_CanoR_1	673	683	PF00244	0.625
LIG_14-3-3_CanoR_1	717	725	PF00244	0.642
LIG_14-3-3_CanoR_1	855	861	PF00244	0.335
LIG_14-3-3_CanoR_1	869	877	PF00244	0.331
LIG_14-3-3_CanoR_1	960	970	PF00244	0.332
LIG_14-3-3_CanoR_1	980	986	PF00244	0.270
LIG_BIR_II_1	1	5	PF00653	0.721
LIG_BIR_III_1	1	5	PF00653	0.670
LIG_BIR_III_2	1119	1123	PF00653	0.472
LIG_BIR_III_3	1	5	PF00653	0.670
LIG_BRCT_BRCA1_1	426	430	PF00533	0.591
LIG_BRCT_BRCA1_1	51	55	PF00533	0.613
LIG_BRCT_BRCA1_1	966	970	PF00533	0.332
LIG_BRCT_BRCA1_2	966	972	PF00533	0.326
LIG_Clathr_ClatBox_1	417	421	PF01394	0.585
LIG_deltaCOP1_diTrp_1	302	308	PF00928	0.644
LIG_FHA_1	1137	1143	PF00498	0.424
LIG_FHA_1	139	145	PF00498	0.636
LIG_FHA_1	15	21	PF00498	0.617
LIG_FHA_1	173	179	PF00498	0.681
LIG_FHA_1	397	403	PF00498	0.711
LIG_FHA_1	49	55	PF00498	0.632
LIG_FHA_1	662	668	PF00498	0.686
LIG_FHA_1	703	709	PF00498	0.633
LIG_FHA_1	747	753	PF00498	0.520
LIG_FHA_1	898	904	PF00498	0.213
LIG_FHA_1	963	969	PF00498	0.499
LIG_FHA_2	161	167	PF00498	0.745
LIG_FHA_2	297	303	PF00498	0.721
LIG_FHA_2	309	315	PF00498	0.576
LIG_FHA_2	393	399	PF00498	0.740
LIG_FHA_2	452	458	PF00498	0.620
LIG_FHA_2	524	530	PF00498	0.584
LIG_FHA_2	547	553	PF00498	0.442
LIG_FHA_2	69	75	PF00498	0.578
LIG_FHA_2	855	861	PF00498	0.332
LIG_FHA_2	914	920	PF00498	0.435
LIG_LIR_Apic_2	389	393	PF02991	0.578
LIG_LIR_Gen_1	338	347	PF02991	0.695
LIG_LIR_Gen_1	967	978	PF02991	0.441
LIG_LIR_LC3C_4	850	853	PF02991	0.332
LIG_LIR_Nem_3	1097	1103	PF02991	0.383
LIG_LIR_Nem_3	196	201	PF02991	0.543
LIG_LIR_Nem_3	338	343	PF02991	0.693
LIG_LIR_Nem_3	880	885	PF02991	0.343
LIG_LIR_Nem_3	967	973	PF02991	0.441
LIG_NRBOX	1091	1097	PF00104	0.404
LIG_NRBOX	412	418	PF00104	0.589
LIG_PCNA_yPIPBox_3	406	417	PF02747	0.524
LIG_PDZ_Class_3	1143	1148	PF00595	0.527
LIG_Pex14_1	304	308	PF04695	0.652
LIG_Pex14_1	756	760	PF04695	0.425
LIG_RPA_C_Fungi	655	667	PF08784	0.512
LIG_SH2_CRK	1100	1104	PF00017	0.460
LIG_SH2_CRK	636	640	PF00017	0.656
LIG_SH2_NCK_1	579	583	PF00017	0.629
LIG_SH2_PTP2	1135	1138	PF00017	0.505
LIG_SH2_STAT3	870	873	PF00017	0.332
LIG_SH2_STAT5	1135	1138	PF00017	0.505
LIG_SH2_STAT5	870	873	PF00017	0.309
LIG_SH3_3	154	160	PF00018	0.716
LIG_SH3_3	186	192	PF00018	0.783
LIG_SH3_3	230	236	PF00018	0.674
LIG_SH3_3	277	283	PF00018	0.661
LIG_SH3_3	390	396	PF00018	0.657
LIG_SH3_3	664	670	PF00018	0.745
LIG_SH3_3	680	686	PF00018	0.540
LIG_SH3_3	698	704	PF00018	0.660
LIG_SH3_3	792	798	PF00018	0.211
LIG_SH3_3	89	95	PF00018	0.744
LIG_SH3_3	928	934	PF00018	0.304
LIG_SH3_3	97	103	PF00018	0.649
LIG_SUMO_SIM_anti_2	411	418	PF11976	0.623
LIG_SUMO_SIM_par_1	801	807	PF11976	0.332
LIG_TRAF2_1	164	167	PF00917	0.683
LIG_TRAF2_1	740	743	PF00917	0.581
LIG_TRAF2_1	809	812	PF00917	0.402
LIG_WW_3	252	256	PF00397	0.467
LIG_WW_3	628	632	PF00397	0.632
MOD_CDC14_SPxK_1	199	202	PF00782	0.601
MOD_CDC14_SPxK_1	628	631	PF00782	0.629
MOD_CDC14_SPxK_1	880	883	PF00782	0.441
MOD_CDK_SPxK_1	196	202	PF00069	0.611
MOD_CDK_SPxK_1	625	631	PF00069	0.630
MOD_CDK_SPxK_1	877	883	PF00069	0.441
MOD_CK1_1	1094	1100	PF00069	0.444
MOD_CK1_1	117	123	PF00069	0.668
MOD_CK1_1	138	144	PF00069	0.641
MOD_CK1_1	270	276	PF00069	0.718
MOD_CK1_1	331	337	PF00069	0.749
MOD_CK1_1	345	351	PF00069	0.561
MOD_CK1_1	358	364	PF00069	0.695
MOD_CK1_1	380	386	PF00069	0.700
MOD_CK1_1	389	395	PF00069	0.598
MOD_CK1_1	474	480	PF00069	0.632
MOD_CK1_1	564	570	PF00069	0.609
MOD_CK1_1	611	617	PF00069	0.645
MOD_CK1_1	623	629	PF00069	0.617
MOD_CK1_1	642	648	PF00069	0.562
MOD_CK1_1	677	683	PF00069	0.562
MOD_CK1_1	68	74	PF00069	0.677
MOD_CK1_1	713	719	PF00069	0.609
MOD_CK1_1	835	841	PF00069	0.311
MOD_CK1_1	996	1002	PF00069	0.513
MOD_CK2_1	160	166	PF00069	0.677
MOD_CK2_1	392	398	PF00069	0.737
MOD_CK2_1	451	457	PF00069	0.713
MOD_CK2_1	806	812	PF00069	0.336
MOD_CK2_1	820	826	PF00069	0.380
MOD_CK2_1	930	936	PF00069	0.350
MOD_CK2_1	98	104	PF00069	0.546
MOD_DYRK1A_RPxSP_1	925	929	PF00069	0.441
MOD_GlcNHglycan	1003	1007	PF01048	0.601
MOD_GlcNHglycan	1015	1018	PF01048	0.638
MOD_GlcNHglycan	1035	1038	PF01048	0.621
MOD_GlcNHglycan	1065	1068	PF01048	0.422
MOD_GlcNHglycan	107	110	PF01048	0.529
MOD_GlcNHglycan	1088	1091	PF01048	0.523
MOD_GlcNHglycan	129	132	PF01048	0.643
MOD_GlcNHglycan	182	185	PF01048	0.637
MOD_GlcNHglycan	23	26	PF01048	0.679
MOD_GlcNHglycan	240	243	PF01048	0.494
MOD_GlcNHglycan	269	272	PF01048	0.711
MOD_GlcNHglycan	280	283	PF01048	0.563
MOD_GlcNHglycan	333	336	PF01048	0.663
MOD_GlcNHglycan	429	433	PF01048	0.631
MOD_GlcNHglycan	467	471	PF01048	0.706
MOD_GlcNHglycan	483	486	PF01048	0.544
MOD_GlcNHglycan	526	529	PF01048	0.711
MOD_GlcNHglycan	580	583	PF01048	0.637
MOD_GlcNHglycan	587	590	PF01048	0.685
MOD_GlcNHglycan	602	605	PF01048	0.560
MOD_GlcNHglycan	610	613	PF01048	0.663
MOD_GlcNHglycan	618	623	PF01048	0.699
MOD_GlcNHglycan	649	652	PF01048	0.706
MOD_GlcNHglycan	667	670	PF01048	0.583
MOD_GlcNHglycan	67	70	PF01048	0.685
MOD_GlcNHglycan	676	679	PF01048	0.594
MOD_GlcNHglycan	693	696	PF01048	0.729
MOD_GlcNHglycan	764	767	PF01048	0.659
MOD_GlcNHglycan	772	775	PF01048	0.626
MOD_GlcNHglycan	832	835	PF01048	0.489
MOD_GlcNHglycan	897	900	PF01048	0.328
MOD_GlcNHglycan	936	939	PF01048	0.448
MOD_GlcNHglycan	943	946	PF01048	0.342
MOD_GlcNHglycan	995	998	PF01048	0.592
MOD_GSK3_1	1053	1060	PF00069	0.393
MOD_GSK3_1	1091	1098	PF00069	0.504
MOD_GSK3_1	135	142	PF00069	0.551
MOD_GSK3_1	156	163	PF00069	0.655
MOD_GSK3_1	21	28	PF00069	0.748
MOD_GSK3_1	321	328	PF00069	0.763
MOD_GSK3_1	331	338	PF00069	0.624
MOD_GSK3_1	358	365	PF00069	0.820
MOD_GSK3_1	392	399	PF00069	0.780
MOD_GSK3_1	424	431	PF00069	0.534
MOD_GSK3_1	451	458	PF00069	0.635
MOD_GSK3_1	466	473	PF00069	0.721
MOD_GSK3_1	476	483	PF00069	0.600
MOD_GSK3_1	503	510	PF00069	0.632
MOD_GSK3_1	520	527	PF00069	0.496
MOD_GSK3_1	562	569	PF00069	0.442
MOD_GSK3_1	625	632	PF00069	0.642
MOD_GSK3_1	635	642	PF00069	0.702
MOD_GSK3_1	661	668	PF00069	0.772
MOD_GSK3_1	802	809	PF00069	0.444
MOD_GSK3_1	830	837	PF00069	0.303
MOD_GSK3_1	843	850	PF00069	0.475
MOD_GSK3_1	90	97	PF00069	0.738
MOD_GSK3_1	913	920	PF00069	0.507
MOD_GSK3_1	921	928	PF00069	0.347
MOD_GSK3_1	930	937	PF00069	0.349
MOD_GSK3_1	941	948	PF00069	0.339
MOD_GSK3_1	958	965	PF00069	0.484
MOD_GSK3_1	98	105	PF00069	0.674
MOD_LATS_1	1071	1077	PF00433	0.487
MOD_N-GLC_1	352	357	PF02516	0.545
MOD_N-GLC_1	422	427	PF02516	0.705
MOD_N-GLC_1	599	604	PF02516	0.657
MOD_N-GLC_1	962	967	PF02516	0.381
MOD_N-GLC_2	1059	1061	PF02516	0.457
MOD_N-GLC_2	555	557	PF02516	0.387
MOD_NEK2_1	1095	1100	PF00069	0.499
MOD_NEK2_1	127	132	PF00069	0.617
MOD_NEK2_1	308	313	PF00069	0.673
MOD_NEK2_1	42	47	PF00069	0.672
MOD_NEK2_1	434	439	PF00069	0.653
MOD_NEK2_1	481	486	PF00069	0.628
MOD_NEK2_1	493	498	PF00069	0.511
MOD_NEK2_1	507	512	PF00069	0.580
MOD_NEK2_1	522	527	PF00069	0.573
MOD_NEK2_1	546	551	PF00069	0.496
MOD_NEK2_1	562	567	PF00069	0.551
MOD_NEK2_1	861	866	PF00069	0.335
MOD_NEK2_1	973	978	PF00069	0.502
MOD_NEK2_2	371	376	PF00069	0.612
MOD_NEK2_2	50	55	PF00069	0.479
MOD_PIKK_1	42	48	PF00454	0.653
MOD_PIKK_1	702	708	PF00454	0.592
MOD_PIKK_1	90	96	PF00454	0.678
MOD_PIKK_1	917	923	PF00454	0.381
MOD_PKA_1	115	121	PF00069	0.598
MOD_PKA_2	1125	1131	PF00069	0.447
MOD_PKA_2	114	120	PF00069	0.714
MOD_PKA_2	125	131	PF00069	0.644
MOD_PKA_2	345	351	PF00069	0.529
MOD_PKA_2	432	438	PF00069	0.559
MOD_PKA_2	481	487	PF00069	0.509
MOD_PKA_2	623	629	PF00069	0.605
MOD_PKA_2	656	662	PF00069	0.547
MOD_PKA_2	713	719	PF00069	0.721
MOD_PKA_2	762	768	PF00069	0.563
MOD_PKA_2	854	860	PF00069	0.335
MOD_PKA_2	868	874	PF00069	0.331
MOD_PKA_2	961	967	PF00069	0.332
MOD_PKB_1	319	327	PF00069	0.658
MOD_PKB_1	939	947	PF00069	0.441
MOD_PKB_1	960	968	PF00069	0.441
MOD_Plk_1	352	358	PF00069	0.545
MOD_Plk_1	861	867	PF00069	0.332
MOD_Plk_2-3	286	292	PF00069	0.521
MOD_Plk_2-3	451	457	PF00069	0.682
MOD_Plk_2-3	98	104	PF00069	0.543
MOD_Plk_4	1091	1097	PF00069	0.447
MOD_Plk_4	1099	1105	PF00069	0.373
MOD_Plk_4	50	56	PF00069	0.628
MOD_Plk_4	791	797	PF00069	0.332
MOD_Plk_4	847	853	PF00069	0.332
MOD_ProDKin_1	1053	1059	PF00069	0.355
MOD_ProDKin_1	107	113	PF00069	0.521
MOD_ProDKin_1	117	123	PF00069	0.684
MOD_ProDKin_1	148	154	PF00069	0.606
MOD_ProDKin_1	156	162	PF00069	0.620
MOD_ProDKin_1	185	191	PF00069	0.703
MOD_ProDKin_1	196	202	PF00069	0.574
MOD_ProDKin_1	245	251	PF00069	0.570
MOD_ProDKin_1	265	271	PF00069	0.623
MOD_ProDKin_1	323	329	PF00069	0.695
MOD_ProDKin_1	358	364	PF00069	0.783
MOD_ProDKin_1	377	383	PF00069	0.572
MOD_ProDKin_1	389	395	PF00069	0.675
MOD_ProDKin_1	424	430	PF00069	0.644
MOD_ProDKin_1	625	631	PF00069	0.630
MOD_ProDKin_1	635	641	PF00069	0.655
MOD_ProDKin_1	700	706	PF00069	0.550
MOD_ProDKin_1	715	721	PF00069	0.578
MOD_ProDKin_1	806	812	PF00069	0.303
MOD_ProDKin_1	877	883	PF00069	0.332
MOD_ProDKin_1	88	94	PF00069	0.753
MOD_ProDKin_1	923	929	PF00069	0.334
MOD_ProDKin_1	930	936	PF00069	0.328
MOD_SUMO_rev_2	850	858	PF00179	0.332
TRG_DiLeu_BaEn_1	409	414	PF01217	0.585
TRG_DiLeu_BaEn_1	872	877	PF01217	0.332
TRG_DiLeu_BaEn_2	965	971	PF01217	0.332
TRG_DiLeu_BaLyEn_6	157	162	PF01217	0.689
TRG_DiLeu_LyEn_5	872	877	PF01217	0.332
TRG_ENDOCYTIC_2	1100	1103	PF00928	0.406
TRG_ENDOCYTIC_2	1135	1138	PF00928	0.505
TRG_ER_diArg_1	1110	1113	PF00400	0.568
TRG_ER_diArg_1	114	116	PF00400	0.685
TRG_ER_diArg_1	574	577	PF00400	0.497
TRG_ER_diArg_1	751	754	PF00400	0.560
TRG_ER_diArg_1	874	876	PF00400	0.475
TRG_ER_diArg_1	939	942	PF00400	0.496
TRG_ER_diArg_1	959	962	PF00400	0.339
TRG_NLS_MonoExtC_3	318	323	PF00514	0.662
TRG_NLS_MonoExtN_4	317	324	PF00514	0.661

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEQ9	Leptomonas seymouri	36%	100%
A0A3Q8IEY2	Leishmania donovani	83%	100%
A4HDI9	Leishmania braziliensis	65%	99%
A4I0Z0	Leishmania infantum	84%	100%
Q4QAH9	Leishmania major	82%	100%