LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AWX6_LEIMU
TriTrypDb:
LmxM.24.1330
Length:
85

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 9
GO:0110165 cellular anatomical entity 1 9
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Expansion

Sequence features

E9AWX6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AWX6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 15 17 PF00675 0.465
CLV_PCSK_KEX2_1 15 17 PF00082 0.445
CLV_PCSK_SKI1_1 39 43 PF00082 0.326
DOC_MAPK_gen_1 52 61 PF00069 0.524
DOC_MAPK_MEF2A_6 54 63 PF00069 0.491
LIG_14-3-3_CanoR_1 15 21 PF00244 0.645
LIG_BIR_II_1 1 5 PF00653 0.623
LIG_FHA_1 56 62 PF00498 0.475
LIG_FHA_2 26 32 PF00498 0.538
LIG_LIR_Apic_2 40 46 PF02991 0.598
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PCA5 Leptomonas seymouri 80% 93%
A0A0S4J5H3 Bodo saltans 57% 69%
A0A3S7WYH2 Leishmania donovani 90% 100%
A4HDK9 Leishmania braziliensis 78% 100%
A4I0X2 Leishmania infantum 90% 100%
C9ZWH5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 63% 97%
Q4QAJ8 Leishmania major 88% 100%
V5BB00 Trypanosoma cruzi 58% 97%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS