DNA-directed DNA polymerase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA polymerase theta

Species:

Leishmania mexicana

UniProt:

E9AWT0_LEIMU

TriTrypDb:

LmxM.24.0890

Length:

1171

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9AWT0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AWT0

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006259	DNA metabolic process	4	7
GO:0006260	DNA replication	5	7
GO:0006261	DNA-templated DNA replication	6	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0043170	macromolecule metabolic process	3	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044260	obsolete cellular macromolecule metabolic process	3	7
GO:0046483	heterocycle metabolic process	3	7
GO:0071704	organic substance metabolic process	2	7
GO:0090304	nucleic acid metabolic process	4	7
GO:1901360	organic cyclic compound metabolic process	3	7
GO:0000731	DNA synthesis involved in DNA repair	6	1
GO:0006281	DNA repair	5	1
GO:0006301	postreplication repair	6	1
GO:0006302	double-strand break repair	6	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0009058	biosynthetic process	2	1
GO:0009059	macromolecule biosynthetic process	4	1
GO:0018130	heterocycle biosynthetic process	4	1
GO:0019438	aromatic compound biosynthetic process	4	1
GO:0019985	translesion synthesis	7	1
GO:0033554	cellular response to stress	3	1
GO:0034654	nucleobase-containing compound biosynthetic process	4	1
GO:0044249	cellular biosynthetic process	3	1
GO:0044271	cellular nitrogen compound biosynthetic process	4	1
GO:0050896	response to stimulus	1	1
GO:0051716	cellular response to stimulus	2	1
GO:0071897	DNA biosynthetic process	5	1
GO:1901362	organic cyclic compound biosynthetic process	4	1
GO:1901576	organic substance biosynthetic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003677	DNA binding	4	7
GO:0003824	catalytic activity	1	7
GO:0003887	DNA-directed DNA polymerase activity	5	7
GO:0005488	binding	1	7
GO:0016740	transferase activity	2	7
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	7
GO:0016779	nucleotidyltransferase activity	4	7
GO:0034061	DNA polymerase activity	4	7
GO:0097159	organic cyclic compound binding	2	7
GO:0140097	catalytic activity, acting on DNA	3	7
GO:0140640	catalytic activity, acting on a nucleic acid	2	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	425	429	PF00656	0.807
CLV_C14_Caspase3-7	436	440	PF00656	0.575
CLV_C14_Caspase3-7	454	458	PF00656	0.559
CLV_C14_Caspase3-7	536	540	PF00656	0.635
CLV_MEL_PAP_1	1152	1158	PF00089	0.346
CLV_MEL_PAP_1	604	610	PF00089	0.489
CLV_NRD_NRD_1	1023	1025	PF00675	0.419
CLV_NRD_NRD_1	1054	1056	PF00675	0.346
CLV_NRD_NRD_1	1067	1069	PF00675	0.346
CLV_NRD_NRD_1	163	165	PF00675	0.784
CLV_NRD_NRD_1	191	193	PF00675	0.762
CLV_NRD_NRD_1	38	40	PF00675	0.647
CLV_NRD_NRD_1	494	496	PF00675	0.561
CLV_NRD_NRD_1	512	514	PF00675	0.769
CLV_NRD_NRD_1	524	526	PF00675	0.647
CLV_NRD_NRD_1	682	684	PF00675	0.488
CLV_NRD_NRD_1	7	9	PF00675	0.774
CLV_NRD_NRD_1	760	762	PF00675	0.625
CLV_PCSK_FUR_1	520	524	PF00082	0.742
CLV_PCSK_KEX2_1	1023	1025	PF00082	0.419
CLV_PCSK_KEX2_1	1066	1068	PF00082	0.346
CLV_PCSK_KEX2_1	191	193	PF00082	0.763
CLV_PCSK_KEX2_1	38	40	PF00082	0.647
CLV_PCSK_KEX2_1	494	496	PF00082	0.646
CLV_PCSK_KEX2_1	511	513	PF00082	0.716
CLV_PCSK_KEX2_1	522	524	PF00082	0.730
CLV_PCSK_KEX2_1	7	9	PF00082	0.737
CLV_PCSK_KEX2_1	87	89	PF00082	0.797
CLV_PCSK_PC1ET2_1	511	513	PF00082	0.725
CLV_PCSK_PC1ET2_1	87	89	PF00082	0.797
CLV_PCSK_PC7_1	518	524	PF00082	0.705
CLV_PCSK_SKI1_1	248	252	PF00082	0.634
CLV_PCSK_SKI1_1	288	292	PF00082	0.570
CLV_PCSK_SKI1_1	328	332	PF00082	0.574
CLV_PCSK_SKI1_1	338	342	PF00082	0.558
CLV_PCSK_SKI1_1	397	401	PF00082	0.638
CLV_PCSK_SKI1_1	512	516	PF00082	0.749
CLV_PCSK_SKI1_1	551	555	PF00082	0.622
CLV_PCSK_SKI1_1	831	835	PF00082	0.336
CLV_Separin_Metazoa	1128	1132	PF03568	0.619
CLV_Separin_Metazoa	705	709	PF03568	0.745
DEG_APCC_DBOX_1	247	255	PF00400	0.631
DEG_APCC_DBOX_1	347	355	PF00400	0.701
DEG_APCC_DBOX_1	367	375	PF00400	0.398
DEG_APCC_DBOX_1	752	760	PF00400	0.599
DEG_SCF_FBW7_1	320	327	PF00400	0.380
DEG_SCF_FBW7_2	170	176	PF00400	0.794
DEG_SPOP_SBC_1	295	299	PF00917	0.640
DEG_SPOP_SBC_1	70	74	PF00917	0.787
DOC_CDC14_PxL_1	311	319	PF14671	0.609
DOC_CKS1_1	170	175	PF01111	0.792
DOC_CKS1_1	321	326	PF01111	0.386
DOC_CYCLIN_RxL_1	322	333	PF00134	0.575
DOC_CYCLIN_RxL_1	334	346	PF00134	0.566
DOC_CYCLIN_RxL_1	866	875	PF00134	0.480
DOC_CYCLIN_yCln2_LP_2	1146	1152	PF00134	0.546
DOC_CYCLIN_yCln2_LP_2	15	21	PF00134	0.769
DOC_MAPK_DCC_7	1145	1154	PF00069	0.536
DOC_MAPK_gen_1	1142	1152	PF00069	0.546
DOC_MAPK_gen_1	38	48	PF00069	0.755
DOC_MAPK_gen_1	683	689	PF00069	0.455
DOC_MAPK_gen_1	761	769	PF00069	0.619
DOC_MAPK_gen_1	87	94	PF00069	0.777
DOC_MAPK_MEF2A_6	1142	1150	PF00069	0.546
DOC_MAPK_MEF2A_6	368	375	PF00069	0.734
DOC_MAPK_MEF2A_6	762	771	PF00069	0.701
DOC_MAPK_MEF2A_6	87	94	PF00069	0.777
DOC_MAPK_MEF2A_6	964	971	PF00069	0.546
DOC_PP1_RVXF_1	336	342	PF00149	0.554
DOC_PP2B_LxvP_1	1146	1149	PF13499	0.546
DOC_PP2B_LxvP_1	951	954	PF13499	0.546
DOC_PP4_FxxP_1	375	378	PF00568	0.747
DOC_USP7_MATH_1	1043	1047	PF00917	0.619
DOC_USP7_MATH_1	121	125	PF00917	0.786
DOC_USP7_MATH_1	127	131	PF00917	0.698
DOC_USP7_MATH_1	132	136	PF00917	0.615
DOC_USP7_MATH_1	160	164	PF00917	0.737
DOC_USP7_MATH_1	250	254	PF00917	0.630
DOC_USP7_MATH_1	271	275	PF00917	0.544
DOC_USP7_MATH_1	576	580	PF00917	0.710
DOC_USP7_MATH_1	671	675	PF00917	0.751
DOC_USP7_MATH_1	68	72	PF00917	0.797
DOC_USP7_MATH_1	722	726	PF00917	0.720
DOC_USP7_MATH_1	792	796	PF00917	0.707
DOC_USP7_MATH_1	841	845	PF00917	0.540
DOC_USP7_UBL2_3	762	766	PF12436	0.613
DOC_WW_Pin1_4	1007	1012	PF00397	0.532
DOC_WW_Pin1_4	169	174	PF00397	0.789
DOC_WW_Pin1_4	24	29	PF00397	0.739
DOC_WW_Pin1_4	320	325	PF00397	0.413
DOC_WW_Pin1_4	596	601	PF00397	0.629
DOC_WW_Pin1_4	606	611	PF00397	0.534
DOC_WW_Pin1_4	700	705	PF00397	0.671
DOC_WW_Pin1_4	78	83	PF00397	0.793
DOC_WW_Pin1_4	839	844	PF00397	0.573
LIG_14-3-3_CanoR_1	1055	1059	PF00244	0.546
LIG_14-3-3_CanoR_1	1095	1099	PF00244	0.619
LIG_14-3-3_CanoR_1	1155	1161	PF00244	0.466
LIG_14-3-3_CanoR_1	164	171	PF00244	0.776
LIG_14-3-3_CanoR_1	241	247	PF00244	0.654
LIG_14-3-3_CanoR_1	494	501	PF00244	0.553
LIG_14-3-3_CanoR_1	683	688	PF00244	0.461
LIG_14-3-3_CanoR_1	696	704	PF00244	0.645
LIG_14-3-3_CanoR_1	796	802	PF00244	0.409
LIG_14-3-3_CanoR_1	814	820	PF00244	0.500
LIG_14-3-3_CanoR_1	854	859	PF00244	0.515
LIG_Actin_WH2_2	1021	1039	PF00022	0.530
LIG_Actin_WH2_2	1129	1147	PF00022	0.619
LIG_Actin_WH2_2	643	661	PF00022	0.552
LIG_APCC_ABBA_1	1111	1116	PF00400	0.546
LIG_APCC_ABBA_1	887	892	PF00400	0.619
LIG_APCC_ABBAyCdc20_2	397	403	PF00400	0.595
LIG_BIR_III_2	168	172	PF00653	0.773
LIG_BIR_III_2	197	201	PF00653	0.699
LIG_BRCT_BRCA1_1	134	138	PF00533	0.535
LIG_BRCT_BRCA1_1	883	887	PF00533	0.549
LIG_BRCT_BRCA1_1	911	915	PF00533	0.546
LIG_Clathr_ClatBox_1	47	51	PF01394	0.751
LIG_eIF4E_1	311	317	PF01652	0.611
LIG_eIF4E_1	337	343	PF01652	0.560
LIG_FHA_1	1104	1110	PF00498	0.424
LIG_FHA_1	1151	1157	PF00498	0.411
LIG_FHA_1	135	141	PF00498	0.572
LIG_FHA_1	170	176	PF00498	0.561
LIG_FHA_1	221	227	PF00498	0.587
LIG_FHA_1	296	302	PF00498	0.620
LIG_FHA_1	321	327	PF00498	0.573
LIG_FHA_1	344	350	PF00498	0.663
LIG_FHA_1	414	420	PF00498	0.797
LIG_FHA_1	550	556	PF00498	0.644
LIG_FHA_1	789	795	PF00498	0.668
LIG_FHA_1	810	816	PF00498	0.524
LIG_FHA_1	945	951	PF00498	0.546
LIG_FHA_2	1037	1043	PF00498	0.619
LIG_FHA_2	38	44	PF00498	0.766
LIG_FHA_2	61	67	PF00498	0.767
LIG_FHA_2	616	622	PF00498	0.509
LIG_FHA_2	642	648	PF00498	0.633
LIG_FHA_2	700	706	PF00498	0.746
LIG_FHA_2	84	90	PF00498	0.772
LIG_FHA_2	861	867	PF00498	0.585
LIG_GBD_Chelix_1	970	978	PF00786	0.346
LIG_LIR_Apic_2	1116	1122	PF02991	0.546
LIG_LIR_Apic_2	857	861	PF02991	0.411
LIG_LIR_Gen_1	554	565	PF02991	0.662
LIG_LIR_Gen_1	618	627	PF02991	0.491
LIG_LIR_Gen_1	912	923	PF02991	0.546
LIG_LIR_Nem_3	1097	1101	PF02991	0.619
LIG_LIR_Nem_3	1159	1163	PF02991	0.466
LIG_LIR_Nem_3	359	363	PF02991	0.614
LIG_LIR_Nem_3	545	550	PF02991	0.636
LIG_LIR_Nem_3	554	560	PF02991	0.617
LIG_LIR_Nem_3	618	622	PF02991	0.456
LIG_LIR_Nem_3	758	763	PF02991	0.580
LIG_LIR_Nem_3	884	890	PF02991	0.567
LIG_LIR_Nem_3	912	918	PF02991	0.546
LIG_LYPXL_S_1	1028	1032	PF13949	0.330
LIG_LYPXL_yS_3	1029	1032	PF13949	0.546
LIG_LYPXL_yS_3	311	314	PF13949	0.619
LIG_NRBOX	316	322	PF00104	0.584
LIG_NRBOX	335	341	PF00104	0.555
LIG_NRBOX	560	566	PF00104	0.727
LIG_PCNA_PIPBox_1	895	904	PF02747	0.619
LIG_PCNA_yPIPBox_3	939	952	PF02747	0.619
LIG_SH2_CRK	1119	1123	PF00017	0.546
LIG_SH2_CRK	337	341	PF00017	0.558
LIG_SH2_CRK	547	551	PF00017	0.732
LIG_SH2_CRK	629	633	PF00017	0.497
LIG_SH2_CRK	902	906	PF00017	0.546
LIG_SH2_CRK	972	976	PF00017	0.546
LIG_SH2_PTP2	858	861	PF00017	0.494
LIG_SH2_SRC	1101	1104	PF00017	0.546
LIG_SH2_SRC	557	560	PF00017	0.638
LIG_SH2_SRC	858	861	PF00017	0.549
LIG_SH2_STAP1	557	561	PF00017	0.539
LIG_SH2_STAP1	619	623	PF00017	0.492
LIG_SH2_STAT3	239	242	PF00017	0.663
LIG_SH2_STAT5	1035	1038	PF00017	0.546
LIG_SH2_STAT5	1101	1104	PF00017	0.546
LIG_SH2_STAT5	303	306	PF00017	0.660
LIG_SH2_STAT5	714	717	PF00017	0.711
LIG_SH2_STAT5	746	749	PF00017	0.640
LIG_SH2_STAT5	858	861	PF00017	0.549
LIG_SH2_STAT5	902	905	PF00017	0.619
LIG_SH3_2	826	831	PF14604	0.619
LIG_SH3_3	1097	1103	PF00018	0.546
LIG_SH3_3	1145	1151	PF00018	0.619
LIG_SH3_3	144	150	PF00018	0.780
LIG_SH3_3	167	173	PF00018	0.794
LIG_SH3_3	175	181	PF00018	0.686
LIG_SH3_3	23	29	PF00018	0.738
LIG_SH3_3	309	315	PF00018	0.631
LIG_SH3_3	352	358	PF00018	0.724
LIG_SH3_3	535	541	PF00018	0.480
LIG_SH3_3	564	570	PF00018	0.678
LIG_SH3_3	572	578	PF00018	0.751
LIG_SH3_3	667	673	PF00018	0.756
LIG_SH3_3	701	707	PF00018	0.678
LIG_SH3_3	823	829	PF00018	0.598
LIG_SH3_3	856	862	PF00018	0.551
LIG_SH3_3	885	891	PF00018	0.602
LIG_Sin3_3	661	668	PF02671	0.397
LIG_SUMO_SIM_anti_2	1106	1112	PF11976	0.411
LIG_SUMO_SIM_anti_2	370	375	PF11976	0.734
LIG_SUMO_SIM_anti_2	941	947	PF11976	0.519
LIG_SUMO_SIM_par_1	211	216	PF11976	0.693
LIG_SUMO_SIM_par_1	352	359	PF11976	0.625
LIG_SUMO_SIM_par_1	562	569	PF11976	0.668
LIG_SUMO_SIM_par_1	941	947	PF11976	0.546
LIG_TRAF2_1	1039	1042	PF00917	0.619
LIG_TRAF2_1	1125	1128	PF00917	0.494
LIG_TRAF2_1	114	117	PF00917	0.595
LIG_TRAF2_1	40	43	PF00917	0.755
LIG_TRAF2_1	862	865	PF00917	0.619
LIG_TRAF2_1	931	934	PF00917	0.619
LIG_TRAF2_1	99	102	PF00917	0.767
LIG_TRFH_1	887	891	PF08558	0.513
LIG_TYR_ITIM	335	340	PF00017	0.556
LIG_TYR_ITIM	555	560	PF00017	0.641
LIG_TYR_ITIM	712	717	PF00017	0.524
LIG_TYR_ITIM	970	975	PF00017	0.411
LIG_WRC_WIRS_1	1044	1049	PF05994	0.436
LIG_WRC_WIRS_1	910	915	PF05994	0.411
LIG_WW_3	27	31	PF00397	0.549
LIG_WW_3	828	832	PF00397	0.513
MOD_CDC14_SPxK_1	27	30	PF00782	0.541
MOD_CDK_SPxK_1	24	30	PF00069	0.548
MOD_CDK_SPxK_1	839	845	PF00069	0.436
MOD_CK1_1	163	169	PF00069	0.799
MOD_CK1_1	185	191	PF00069	0.753
MOD_CK1_1	274	280	PF00069	0.736
MOD_CK1_1	297	303	PF00069	0.643
MOD_CK1_1	367	373	PF00069	0.604
MOD_CK1_1	37	43	PF00069	0.640
MOD_CK1_1	418	424	PF00069	0.623
MOD_CK1_1	528	534	PF00069	0.747
MOD_CK1_1	59	65	PF00069	0.808
MOD_CK1_1	599	605	PF00069	0.606
MOD_CK1_1	674	680	PF00069	0.529
MOD_CK1_1	69	75	PF00069	0.701
MOD_CK1_1	787	793	PF00069	0.639
MOD_CK1_1	844	850	PF00069	0.436
MOD_CK2_1	1036	1042	PF00069	0.513
MOD_CK2_1	111	117	PF00069	0.875
MOD_CK2_1	1156	1162	PF00069	0.299
MOD_CK2_1	127	133	PF00069	0.548
MOD_CK2_1	240	246	PF00069	0.644
MOD_CK2_1	37	43	PF00069	0.771
MOD_CK2_1	383	389	PF00069	0.437
MOD_CK2_1	418	424	PF00069	0.727
MOD_CK2_1	439	445	PF00069	0.727
MOD_CK2_1	606	612	PF00069	0.553
MOD_CK2_1	699	705	PF00069	0.747
MOD_CK2_1	83	89	PF00069	0.777
MOD_Cter_Amidation	1053	1056	PF01082	0.411
MOD_Cter_Amidation	509	512	PF01082	0.605
MOD_Cter_Amidation	681	684	PF01082	0.493
MOD_GlcNHglycan	1016	1019	PF01048	0.441
MOD_GlcNHglycan	1052	1055	PF01048	0.411
MOD_GlcNHglycan	1085	1088	PF01048	0.513
MOD_GlcNHglycan	122	126	PF01048	0.791
MOD_GlcNHglycan	129	132	PF01048	0.675
MOD_GlcNHglycan	242	245	PF01048	0.569
MOD_GlcNHglycan	273	276	PF01048	0.745
MOD_GlcNHglycan	4	7	PF01048	0.770
MOD_GlcNHglycan	43	46	PF01048	0.750
MOD_GlcNHglycan	502	505	PF01048	0.702
MOD_GlcNHglycan	527	530	PF01048	0.727
MOD_GlcNHglycan	578	581	PF01048	0.663
MOD_GlcNHglycan	601	604	PF01048	0.716
MOD_GlcNHglycan	673	676	PF01048	0.678
MOD_GlcNHglycan	68	71	PF01048	0.784
MOD_GlcNHglycan	839	842	PF01048	0.513
MOD_GlcNHglycan	846	849	PF01048	0.364
MOD_GlcNHglycan	883	886	PF01048	0.356
MOD_GlcNHglycan	926	929	PF01048	0.411
MOD_GlcNHglycan	936	939	PF01048	0.411
MOD_GSK3_1	1050	1057	PF00069	0.411
MOD_GSK3_1	111	118	PF00069	0.803
MOD_GSK3_1	297	304	PF00069	0.673
MOD_GSK3_1	320	327	PF00069	0.627
MOD_GSK3_1	37	44	PF00069	0.790
MOD_GSK3_1	418	425	PF00069	0.749
MOD_GSK3_1	431	438	PF00069	0.713
MOD_GSK3_1	528	535	PF00069	0.721
MOD_GSK3_1	56	63	PF00069	0.527
MOD_GSK3_1	66	73	PF00069	0.780
MOD_GSK3_1	695	702	PF00069	0.637
MOD_GSK3_1	784	791	PF00069	0.784
MOD_GSK3_1	835	842	PF00069	0.402
MOD_N-GLC_1	271	276	PF02516	0.838
MOD_N-GLC_1	634	639	PF02516	0.511
MOD_N-GLC_1	781	786	PF02516	0.521
MOD_N-GLC_1	808	813	PF02516	0.411
MOD_NEK2_1	1036	1041	PF00069	0.513
MOD_NEK2_1	1109	1114	PF00069	0.513
MOD_NEK2_1	1166	1171	PF00069	0.658
MOD_NEK2_1	139	144	PF00069	0.763
MOD_NEK2_1	201	206	PF00069	0.755
MOD_NEK2_1	296	301	PF00069	0.596
MOD_NEK2_1	330	335	PF00069	0.574
MOD_NEK2_1	413	418	PF00069	0.768
MOD_NEK2_1	514	519	PF00069	0.837
MOD_NEK2_1	532	537	PF00069	0.594
MOD_NEK2_1	587	592	PF00069	0.677
MOD_NEK2_1	807	812	PF00069	0.431
MOD_NEK2_2	849	854	PF00069	0.474
MOD_NEK2_2	894	899	PF00069	0.411
MOD_PIKK_1	112	118	PF00454	0.802
MOD_PIKK_1	401	407	PF00454	0.708
MOD_PK_1	7	13	PF00069	0.656
MOD_PK_1	88	94	PF00069	0.777
MOD_PK_1	952	958	PF00069	0.513
MOD_PKA_1	494	500	PF00069	0.549
MOD_PKA_1	683	689	PF00069	0.455
MOD_PKA_1	7	13	PF00069	0.773
MOD_PKA_2	1036	1042	PF00069	0.515
MOD_PKA_2	1054	1060	PF00069	0.238
MOD_PKA_2	1094	1100	PF00069	0.411
MOD_PKA_2	163	169	PF00069	0.785
MOD_PKA_2	240	246	PF00069	0.579
MOD_PKA_2	367	373	PF00069	0.623
MOD_PKA_2	37	43	PF00069	0.672
MOD_PKA_2	494	500	PF00069	0.627
MOD_PKA_2	59	65	PF00069	0.774
MOD_PKA_2	66	72	PF00069	0.702
MOD_PKA_2	695	701	PF00069	0.669
MOD_PKA_2	7	13	PF00069	0.773
MOD_PKA_2	844	850	PF00069	0.432
MOD_PKB_1	39	47	PF00069	0.740
MOD_PKB_1	523	531	PF00069	0.718
MOD_Plk_1	349	355	PF00069	0.625
MOD_Plk_1	634	640	PF00069	0.518
MOD_Plk_1	849	855	PF00069	0.513
MOD_Plk_2-3	350	356	PF00069	0.631
MOD_Plk_2-3	422	428	PF00069	0.749
MOD_Plk_2-3	439	445	PF00069	0.514
MOD_Plk_2-3	860	866	PF00069	0.513
MOD_Plk_4	1031	1037	PF00069	0.397
MOD_Plk_4	1054	1060	PF00069	0.471
MOD_Plk_4	1094	1100	PF00069	0.411
MOD_Plk_4	134	140	PF00069	0.750
MOD_Plk_4	201	207	PF00069	0.752
MOD_Plk_4	297	303	PF00069	0.596
MOD_Plk_4	350	356	PF00069	0.706
MOD_Plk_4	551	557	PF00069	0.584
MOD_Plk_4	854	860	PF00069	0.222
MOD_Plk_4	946	952	PF00069	0.411
MOD_ProDKin_1	1007	1013	PF00069	0.392
MOD_ProDKin_1	169	175	PF00069	0.790
MOD_ProDKin_1	24	30	PF00069	0.745
MOD_ProDKin_1	320	326	PF00069	0.409
MOD_ProDKin_1	596	602	PF00069	0.628
MOD_ProDKin_1	606	612	PF00069	0.533
MOD_ProDKin_1	700	706	PF00069	0.668
MOD_ProDKin_1	78	84	PF00069	0.792
MOD_ProDKin_1	839	845	PF00069	0.450
TRG_DiLeu_BaEn_1	395	400	PF01217	0.652
TRG_DiLeu_BaLyEn_6	221	226	PF01217	0.585
TRG_DiLeu_BaLyEn_6	312	317	PF01217	0.608
TRG_DiLeu_BaLyEn_6	331	336	PF01217	0.570
TRG_DiLeu_BaLyEn_6	510	515	PF01217	0.745
TRG_DiLeu_BaLyEn_6	560	565	PF01217	0.621
TRG_DiLeu_BaLyEn_6	713	718	PF01217	0.609
TRG_DiLeu_BaLyEn_6	918	923	PF01217	0.513
TRG_ENDOCYTIC_2	1029	1032	PF00928	0.411
TRG_ENDOCYTIC_2	311	314	PF00928	0.619
TRG_ENDOCYTIC_2	337	340	PF00928	0.562
TRG_ENDOCYTIC_2	547	550	PF00928	0.633
TRG_ENDOCYTIC_2	557	560	PF00928	0.614
TRG_ENDOCYTIC_2	619	622	PF00928	0.498
TRG_ENDOCYTIC_2	629	632	PF00928	0.454
TRG_ENDOCYTIC_2	714	717	PF00928	0.711
TRG_ENDOCYTIC_2	856	859	PF00928	0.411
TRG_ENDOCYTIC_2	972	975	PF00928	0.411
TRG_ER_diArg_1	1022	1024	PF00400	0.513
TRG_ER_diArg_1	1066	1068	PF00400	0.338
TRG_ER_diArg_1	190	192	PF00400	0.772
TRG_ER_diArg_1	38	41	PF00400	0.642
TRG_ER_diArg_1	480	483	PF00400	0.748
TRG_ER_diArg_1	512	514	PF00400	0.726
TRG_ER_diArg_1	515	518	PF00400	0.721
TRG_ER_diArg_1	520	523	PF00400	0.713
TRG_ER_diArg_1	524	526	PF00400	0.710
TRG_ER_diArg_1	753	756	PF00400	0.566
TRG_NES_CRM1_1	758	773	PF08389	0.700
TRG_NLS_Bipartite_1	494	515	PF00514	0.628
TRG_Pf-PMV_PEXEL_1	1070	1074	PF00026	0.513
TRG_Pf-PMV_PEXEL_1	1135	1139	PF00026	0.411
TRG_Pf-PMV_PEXEL_1	224	228	PF00026	0.480
TRG_Pf-PMV_PEXEL_1	397	402	PF00026	0.641
TRG_Pf-PMV_PEXEL_1	482	486	PF00026	0.746
TRG_Pf-PMV_PEXEL_1	716	721	PF00026	0.701

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6B8	Leptomonas seymouri	50%	100%
A0A3Q8ICZ6	Leishmania donovani	89%	100%
A4HDE5	Leishmania braziliensis	76%	99%
A4I0S8	Leishmania infantum	88%	100%
Q4QAP4	Leishmania major	88%	100%