SUZ domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AWR9_LEIMU

TriTrypDb:

LmxM.24.0780

Length:

296

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AWR9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AWR9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	60	64	PF00656	0.562
CLV_NRD_NRD_1	143	145	PF00675	0.628
CLV_NRD_NRD_1	170	172	PF00675	0.594
CLV_NRD_NRD_1	191	193	PF00675	0.529
CLV_PCSK_FUR_1	189	193	PF00082	0.489
CLV_PCSK_KEX2_1	143	145	PF00082	0.628
CLV_PCSK_KEX2_1	170	172	PF00082	0.594
CLV_PCSK_KEX2_1	191	193	PF00082	0.529
CLV_PCSK_KEX2_1	36	38	PF00082	0.559
CLV_PCSK_PC1ET2_1	36	38	PF00082	0.559
CLV_PCSK_PC7_1	139	145	PF00082	0.627
CLV_PCSK_SKI1_1	198	202	PF00082	0.526
CLV_PCSK_SKI1_1	83	87	PF00082	0.458
CLV_PCSK_SKI1_1	88	92	PF00082	0.483
DEG_APCC_DBOX_1	114	122	PF00400	0.556
DEG_APCC_DBOX_1	197	205	PF00400	0.518
DEG_COP1_1	60	68	PF00400	0.493
DEG_Nend_UBRbox_3	1	3	PF02207	0.514
DEG_SPOP_SBC_1	128	132	PF00917	0.576
DOC_ANK_TNKS_1	151	158	PF00023	0.671
DOC_CYCLIN_RxL_1	83	93	PF00134	0.521
DOC_MAPK_gen_1	186	196	PF00069	0.486
DOC_MAPK_MEF2A_6	96	103	PF00069	0.539
DOC_PP4_FxxP_1	108	111	PF00568	0.616
DOC_PP4_FxxP_1	230	233	PF00568	0.654
DOC_USP7_MATH_1	128	132	PF00917	0.625
DOC_USP7_MATH_1	13	17	PF00917	0.629
DOC_USP7_MATH_1	177	181	PF00917	0.636
DOC_USP7_MATH_1	40	44	PF00917	0.698
DOC_USP7_MATH_1	53	57	PF00917	0.659
DOC_USP7_MATH_1	66	70	PF00917	0.584
DOC_WW_Pin1_4	107	112	PF00397	0.536
DOC_WW_Pin1_4	124	129	PF00397	0.609
DOC_WW_Pin1_4	130	135	PF00397	0.733
DOC_WW_Pin1_4	270	275	PF00397	0.662
DOC_WW_Pin1_4	290	295	PF00397	0.637
LIG_14-3-3_CanoR_1	115	119	PF00244	0.554
LIG_14-3-3_CanoR_1	250	256	PF00244	0.684
LIG_ActinCP_TwfCPI_2	230	239	PF01115	0.620
LIG_BIR_III_4	245	249	PF00653	0.646
LIG_BRCT_BRCA1_1	288	292	PF00533	0.654
LIG_FHA_1	60	66	PF00498	0.509
LIG_FHA_2	75	81	PF00498	0.500
LIG_LIR_Apic_2	106	111	PF02991	0.607
LIG_LIR_Apic_2	228	233	PF02991	0.668
LIG_LIR_Gen_1	208	218	PF02991	0.557
LIG_LIR_Gen_1	7	15	PF02991	0.548
LIG_LIR_Nem_3	208	214	PF02991	0.542
LIG_LIR_Nem_3	270	275	PF02991	0.607
LIG_LIR_Nem_3	289	295	PF02991	0.622
LIG_LIR_Nem_3	7	12	PF02991	0.540
LIG_PCNA_yPIPBox_3	83	91	PF02747	0.462
LIG_SH2_CRK	172	176	PF00017	0.633
LIG_SH2_CRK	211	215	PF00017	0.621
LIG_SH2_CRK	9	13	PF00017	0.547
LIG_SH2_NCK_1	116	120	PF00017	0.625
LIG_SH2_STAP1	9	13	PF00017	0.547
LIG_SH2_STAT5	116	119	PF00017	0.669
LIG_SH2_STAT5	187	190	PF00017	0.448
LIG_SH2_STAT5	234	237	PF00017	0.625
LIG_SH2_STAT5	275	278	PF00017	0.512
LIG_SH3_1	288	294	PF00018	0.560
LIG_SH3_3	288	294	PF00018	0.628
LIG_TRAF2_1	16	19	PF00917	0.629
LIG_TRAF2_1	180	183	PF00917	0.520
LIG_TYR_ITIM	209	214	PF00017	0.548
MOD_CK1_1	130	136	PF00069	0.617
MOD_CK1_1	251	257	PF00069	0.720
MOD_CK1_1	270	276	PF00069	0.568
MOD_CK1_1	61	67	PF00069	0.720
MOD_CK2_1	13	19	PF00069	0.565
MOD_CK2_1	177	183	PF00069	0.526
MOD_CK2_1	74	80	PF00069	0.516
MOD_GlcNHglycan	166	169	PF01048	0.614
MOD_GlcNHglycan	269	272	PF01048	0.623
MOD_GlcNHglycan	288	291	PF01048	0.628
MOD_GlcNHglycan	6	9	PF01048	0.602
MOD_GSK3_1	124	131	PF00069	0.627
MOD_GSK3_1	286	293	PF00069	0.692
MOD_GSK3_1	53	60	PF00069	0.693
MOD_N-GLC_1	177	182	PF02516	0.541
MOD_NEK2_1	212	217	PF00069	0.563
MOD_NEK2_1	27	32	PF00069	0.567
MOD_PIKK_1	144	150	PF00454	0.641
MOD_PIKK_1	212	218	PF00454	0.599
MOD_PKA_2	114	120	PF00069	0.552
MOD_PKA_2	13	19	PF00069	0.565
MOD_PKA_2	249	255	PF00069	0.585
MOD_PKA_2	48	54	PF00069	0.603
MOD_PKB_1	265	273	PF00069	0.617
MOD_Plk_1	27	33	PF00069	0.547
MOD_Plk_2-3	205	211	PF00069	0.535
MOD_Plk_4	27	33	PF00069	0.612
MOD_Plk_4	74	80	PF00069	0.500
MOD_ProDKin_1	107	113	PF00069	0.536
MOD_ProDKin_1	124	130	PF00069	0.611
MOD_ProDKin_1	270	276	PF00069	0.664
MOD_ProDKin_1	290	296	PF00069	0.630
TRG_ENDOCYTIC_2	211	214	PF00928	0.551
TRG_ENDOCYTIC_2	9	12	PF00928	0.548
TRG_ER_diArg_1	149	152	PF00400	0.611
TRG_ER_diArg_1	169	171	PF00400	0.719
TRG_ER_diArg_1	188	191	PF00400	0.418
TRG_ER_diArg_1	255	258	PF00400	0.665
TRG_ER_diArg_1	264	267	PF00400	0.578
TRG_Pf-PMV_PEXEL_1	88	93	PF00026	0.483

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5G1	Leptomonas seymouri	44%	99%
A0A3Q8IBA4	Leishmania donovani	84%	95%
A4HDD6	Leishmania braziliensis	71%	100%
A4I0R7	Leishmania infantum	83%	95%
Q4QAQ5	Leishmania major	84%	100%