Hypothetical predicted transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical predicted transmembrane protein

Species:

Leishmania mexicana

UniProt:

E9AWQ9_LEIMU

TriTrypDb:

LmxM.24.0690

Length:

153

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	7
GO:0110165	cellular anatomical entity	1	7

Expansion

Sequence features

E9AWQ9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AWQ9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	131	135	PF00656	0.416
CLV_NRD_NRD_1	102	104	PF00675	0.522
CLV_NRD_NRD_1	3	5	PF00675	0.472
CLV_NRD_NRD_1	47	49	PF00675	0.433
CLV_PCSK_KEX2_1	108	110	PF00082	0.725
CLV_PCSK_KEX2_1	116	118	PF00082	0.685
CLV_PCSK_KEX2_1	3	5	PF00082	0.457
CLV_PCSK_KEX2_1	47	49	PF00082	0.433
CLV_PCSK_PC1ET2_1	108	110	PF00082	0.725
CLV_PCSK_PC1ET2_1	116	118	PF00082	0.685
CLV_PCSK_SKI1_1	103	107	PF00082	0.622
CLV_PCSK_SKI1_1	29	33	PF00082	0.459
CLV_PCSK_SKI1_1	66	70	PF00082	0.573
CLV_Separin_Metazoa	19	23	PF03568	0.711
DEG_APCC_DBOX_1	132	140	PF00400	0.533
DEG_Nend_Nbox_1	1	3	PF02207	0.713
DEG_SPOP_SBC_1	12	16	PF00917	0.722
DOC_CYCLIN_RxL_1	60	72	PF00134	0.766
DOC_PP4_FxxP_1	10	13	PF00568	0.752
DOC_SPAK_OSR1_1	9	13	PF12202	0.726
DOC_USP7_MATH_1	13	17	PF00917	0.735
DOC_USP7_UBL2_3	104	108	PF12436	0.312
DOC_WW_Pin1_4	134	139	PF00397	0.614
DOC_WW_Pin1_4	69	74	PF00397	0.488
LIG_14-3-3_CanoR_1	47	52	PF00244	0.619
LIG_FHA_1	6	12	PF00498	0.726
LIG_FHA_2	32	38	PF00498	0.714
LIG_LIR_Apic_2	8	13	PF02991	0.698
LIG_LIR_Gen_1	140	148	PF02991	0.602
LIG_LIR_Gen_1	37	45	PF02991	0.712
LIG_LIR_Nem_3	140	145	PF02991	0.604
LIG_LIR_Nem_3	37	42	PF02991	0.684
LIG_Pex14_2	86	90	PF04695	0.329
LIG_REV1ctd_RIR_1	103	113	PF16727	0.398
LIG_SH2_CRK	39	43	PF00017	0.676
LIG_SH2_STAP1	39	43	PF00017	0.709
LIG_SH3_3	91	97	PF00018	0.497
LIG_TRAF2_1	126	129	PF00917	0.625
LIG_TRAF2_1	138	141	PF00917	0.472
LIG_TRAF2_1	16	19	PF00917	0.562
LIG_WRC_WIRS_1	87	92	PF05994	0.389
MOD_CK1_1	118	124	PF00069	0.524
MOD_CK1_1	5	11	PF00069	0.735
MOD_CK2_1	12	18	PF00069	0.712
MOD_CK2_1	134	140	PF00069	0.603
MOD_Cter_Amidation	114	117	PF01082	0.697
MOD_GlcNHglycan	15	18	PF01048	0.370
MOD_GlcNHglycan	34	37	PF01048	0.576
MOD_GlcNHglycan	55	58	PF01048	0.441
MOD_GlcNHglycan	69	72	PF01048	0.530
MOD_GSK3_1	115	122	PF00069	0.513
MOD_GSK3_1	58	65	PF00069	0.747
MOD_NEK2_1	2	7	PF00069	0.668
MOD_NEK2_1	30	35	PF00069	0.561
MOD_NEK2_1	86	91	PF00069	0.411
MOD_PKA_1	47	53	PF00069	0.570
MOD_PKA_2	118	124	PF00069	0.531
MOD_PKA_2	2	8	PF00069	0.689
MOD_PKA_2	46	52	PF00069	0.643
MOD_PKB_1	117	125	PF00069	0.467
MOD_ProDKin_1	134	140	PF00069	0.613
MOD_ProDKin_1	69	75	PF00069	0.488
TRG_DiLeu_BaEn_1	141	146	PF01217	0.547
TRG_DiLeu_BaEn_1	26	31	PF01217	0.602
TRG_DiLeu_BaEn_3	18	24	PF01217	0.557
TRG_DiLeu_BaEn_4	131	137	PF01217	0.413
TRG_ENDOCYTIC_2	39	42	PF00928	0.677
TRG_ER_diArg_1	2	4	PF00400	0.671
TRG_ER_diLys_1	149	153	PF00400	0.398
TRG_Pf-PMV_PEXEL_1	22	26	PF00026	0.516

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5G4	Leptomonas seymouri	43%	100%
A0A3S7WYC5	Leishmania donovani	81%	100%
A4HDC7	Leishmania braziliensis	61%	100%
A4I0Q7	Leishmania infantum	80%	100%
Q4QAR4	Leishmania major	77%	100%