Putative sugar transporter

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

sugar transporter, putative

Species:

Leishmania mexicana

UniProt:

E9AWQ8_LEIMU

TriTrypDb:

LmxM.24.0680

Length:

538

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	12
GO:0110165	cellular anatomical entity	1	12

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Expansion

Sequence features

E9AWQ8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AWQ8

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	8
GO:0008643	carbohydrate transport	5	7
GO:0009987	cellular process	1	1
GO:0015798	myo-inositol transport	6	1
GO:0015850	organic hydroxy compound transport	5	1
GO:0051179	localization	1	8
GO:0051234	establishment of localization	2	8
GO:0055085	transmembrane transport	2	1
GO:0071702	organic substance transport	4	8

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Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	12
GO:0005365	myo-inositol transmembrane transporter activity	5	1
GO:0015166	polyol transmembrane transporter activity	4	1
GO:0022857	transmembrane transporter activity	2	12
GO:1901618	organic hydroxy compound transmembrane transporter activity	3	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	194	198	PF00656	0.352
CLV_C14_Caspase3-7	436	440	PF00656	0.509
CLV_NRD_NRD_1	305	307	PF00675	0.257
CLV_NRD_NRD_1	70	72	PF00675	0.255
CLV_PCSK_FUR_1	200	204	PF00082	0.152
CLV_PCSK_KEX2_1	202	204	PF00082	0.152
CLV_PCSK_KEX2_1	304	306	PF00082	0.264
CLV_PCSK_KEX2_1	444	446	PF00082	0.404
CLV_PCSK_KEX2_1	70	72	PF00082	0.255
CLV_PCSK_PC1ET2_1	202	204	PF00082	0.152

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0H2VG78	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	31%	100%
A0A0N0P2E1	Leptomonas seymouri	22%	100%
A0A0N0P5V6	Leptomonas seymouri	74%	93%
A0A0S4IKD4	Bodo saltans	23%	100%
A0A0S4IMM5	Bodo saltans	47%	100%
A0A0S4JDF9	Bodo saltans	24%	100%
A0A0S4JEY7	Bodo saltans	24%	100%
A0A0S4JH90	Bodo saltans	23%	100%
A0A1D8PCL1	Candida albicans (strain SC5314 / ATCC MYA-2876)	28%	99%
A0A1D8PH98	Candida albicans (strain SC5314 / ATCC MYA-2876)	32%	97%

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