Putative DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein, putative

Species:

Leishmania mexicana

UniProt:

E9AWQ1_LEIMU

TriTrypDb:

LmxM.24.0610

Length:

1087

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	8
GO:0043226	organelle	2	8
GO:0043227	membrane-bounded organelle	3	8
GO:0043229	intracellular organelle	3	8
GO:0043231	intracellular membrane-bounded organelle	4	8
GO:0110165	cellular anatomical entity	1	9
GO:0005657	replication fork	2	1
GO:0043596	nuclear replication fork	3	1

Expansion

Sequence features

E9AWQ1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AWQ1

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	9
GO:0006259	DNA metabolic process	4	9
GO:0006281	DNA repair	5	9
GO:0006725	cellular aromatic compound metabolic process	3	9
GO:0006807	nitrogen compound metabolic process	2	9
GO:0006950	response to stress	2	9
GO:0006974	DNA damage response	4	9
GO:0008152	metabolic process	1	9
GO:0009987	cellular process	1	9
GO:0031297	replication fork processing	6	9
GO:0033554	cellular response to stress	3	9
GO:0034641	cellular nitrogen compound metabolic process	3	9
GO:0043170	macromolecule metabolic process	3	9
GO:0044237	cellular metabolic process	2	9
GO:0044238	primary metabolic process	2	9
GO:0044260	obsolete cellular macromolecule metabolic process	3	9
GO:0045005	DNA-templated DNA replication maintenance of fidelity	5	9
GO:0046483	heterocycle metabolic process	3	9
GO:0050896	response to stimulus	1	9
GO:0051716	cellular response to stimulus	2	9
GO:0071704	organic substance metabolic process	2	9
GO:0090304	nucleic acid metabolic process	4	9
GO:1901360	organic cyclic compound metabolic process	3	9
GO:0006275	regulation of DNA replication	6	1
GO:0008156	negative regulation of DNA replication	7	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0010605	negative regulation of macromolecule metabolic process	5	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031324	negative regulation of cellular metabolic process	5	1
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	6	1
GO:0048478	obsolete replication fork protection	6	1
GO:0048519	negative regulation of biological process	3	1
GO:0048523	negative regulation of cellular process	4	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051052	regulation of DNA metabolic process	5	1
GO:0051053	negative regulation of DNA metabolic process	6	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051172	negative regulation of nitrogen compound metabolic process	5	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0080090	regulation of primary metabolic process	4	1
GO:0090329	regulation of DNA-templated DNA replication	7	1
GO:2000104	negative regulation of DNA-templated DNA replication	8	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	10
GO:0003676	nucleic acid binding	3	9
GO:0003677	DNA binding	4	9
GO:0003697	single-stranded DNA binding	5	9
GO:0003824	catalytic activity	1	10
GO:0004386	helicase activity	2	7
GO:0005488	binding	1	10
GO:0005524	ATP binding	5	10
GO:0008094	ATP-dependent activity, acting on DNA	2	10
GO:0016491	oxidoreductase activity	2	10
GO:0017076	purine nucleotide binding	4	10
GO:0030554	adenyl nucleotide binding	5	10
GO:0032553	ribonucleotide binding	3	10
GO:0032555	purine ribonucleotide binding	4	10
GO:0032559	adenyl ribonucleotide binding	5	10
GO:0035639	purine ribonucleoside triphosphate binding	4	10
GO:0036094	small molecule binding	2	10
GO:0036310	ATP-dependent DNA/DNA annealing activity	2	9
GO:0043167	ion binding	2	10
GO:0043168	anion binding	3	10
GO:0051213	dioxygenase activity	3	10
GO:0097159	organic cyclic compound binding	2	10
GO:0097367	carbohydrate derivative binding	2	10
GO:0140097	catalytic activity, acting on DNA	3	10
GO:0140640	catalytic activity, acting on a nucleic acid	2	10
GO:0140657	ATP-dependent activity	1	10
GO:0140658	ATP-dependent chromatin remodeler activity	3	10
GO:0140666	annealing activity	4	9
GO:1901265	nucleoside phosphate binding	3	10
GO:1901363	heterocyclic compound binding	2	10
GO:1990814	DNA/DNA annealing activity	5	9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	670	674	PF00656	0.780
CLV_C14_Caspase3-7	985	989	PF00656	0.638
CLV_NRD_NRD_1	1064	1066	PF00675	0.716
CLV_NRD_NRD_1	312	314	PF00675	0.295
CLV_NRD_NRD_1	382	384	PF00675	0.283
CLV_NRD_NRD_1	420	422	PF00675	0.512
CLV_NRD_NRD_1	633	635	PF00675	0.541
CLV_NRD_NRD_1	667	669	PF00675	0.597
CLV_NRD_NRD_1	903	905	PF00675	0.614
CLV_PCSK_FUR_1	383	387	PF00082	0.291
CLV_PCSK_KEX2_1	1064	1066	PF00082	0.716
CLV_PCSK_KEX2_1	299	301	PF00082	0.285
CLV_PCSK_KEX2_1	312	314	PF00082	0.242
CLV_PCSK_KEX2_1	382	384	PF00082	0.283
CLV_PCSK_KEX2_1	385	387	PF00082	0.283
CLV_PCSK_KEX2_1	420	422	PF00082	0.512
CLV_PCSK_KEX2_1	633	635	PF00082	0.541
CLV_PCSK_KEX2_1	667	669	PF00082	0.597
CLV_PCSK_KEX2_1	903	905	PF00082	0.614
CLV_PCSK_KEX2_1	964	966	PF00082	0.643
CLV_PCSK_KEX2_1	980	982	PF00082	0.655
CLV_PCSK_PC1ET2_1	299	301	PF00082	0.285
CLV_PCSK_PC1ET2_1	385	387	PF00082	0.291
CLV_PCSK_PC1ET2_1	964	966	PF00082	0.643
CLV_PCSK_PC1ET2_1	980	982	PF00082	0.655
CLV_PCSK_SKI1_1	1065	1069	PF00082	0.711
CLV_PCSK_SKI1_1	109	113	PF00082	0.508
CLV_PCSK_SKI1_1	176	180	PF00082	0.488
CLV_PCSK_SKI1_1	187	191	PF00082	0.468
CLV_PCSK_SKI1_1	313	317	PF00082	0.289
CLV_PCSK_SKI1_1	377	381	PF00082	0.343
CLV_PCSK_SKI1_1	397	401	PF00082	0.270
CLV_PCSK_SKI1_1	409	413	PF00082	0.286
CLV_PCSK_SKI1_1	448	452	PF00082	0.388
CLV_PCSK_SKI1_1	476	480	PF00082	0.317
CLV_PCSK_SKI1_1	583	587	PF00082	0.380
CLV_PCSK_SKI1_1	904	908	PF00082	0.651
CLV_Separin_Metazoa	495	499	PF03568	0.387
DEG_APCC_DBOX_1	1063	1071	PF00400	0.711
DEG_APCC_DBOX_1	108	116	PF00400	0.462
DEG_APCC_DBOX_1	719	727	PF00400	0.590
DEG_Nend_UBRbox_3	1	3	PF02207	0.475
DEG_ODPH_VHL_1	1014	1025	PF01847	0.586
DEG_ODPH_VHL_1	33	46	PF01847	0.507
DEG_SCF_FBW7_1	317	324	PF00400	0.470
DEG_SCF_FBW7_1	792	798	PF00400	0.511
DEG_SPOP_SBC_1	1038	1042	PF00917	0.721
DEG_SPOP_SBC_1	638	642	PF00917	0.570
DOC_CKS1_1	709	714	PF01111	0.701
DOC_CKS1_1	726	731	PF01111	0.662
DOC_CKS1_1	746	751	PF01111	0.563
DOC_CKS1_1	792	797	PF01111	0.509
DOC_CYCLIN_RxL_1	578	590	PF00134	0.389
DOC_MAPK_DCC_7	126	135	PF00069	0.526
DOC_MAPK_FxFP_2	111	114	PF00069	0.446
DOC_MAPK_gen_1	299	307	PF00069	0.477
DOC_MAPK_gen_1	309	317	PF00069	0.457
DOC_MAPK_gen_1	395	404	PF00069	0.483
DOC_MAPK_MEF2A_6	126	135	PF00069	0.516
DOC_MAPK_MEF2A_6	218	226	PF00069	0.470
DOC_MAPK_MEF2A_6	703	710	PF00069	0.730
DOC_MAPK_MEF2A_6	842	850	PF00069	0.582
DOC_MAPK_MEF2A_6	86	94	PF00069	0.553
DOC_MAPK_MEF2A_6	949	957	PF00069	0.728
DOC_MAPK_RevD_3	951	965	PF00069	0.672
DOC_PP1_RVXF_1	474	481	PF00149	0.483
DOC_PP2B_LxvP_1	1017	1020	PF13499	0.580
DOC_PP4_FxxP_1	111	114	PF00568	0.446
DOC_PP4_FxxP_1	656	659	PF00568	0.674
DOC_SPAK_OSR1_1	358	362	PF12202	0.470
DOC_USP7_MATH_1	1038	1042	PF00917	0.815
DOC_USP7_MATH_1	1058	1062	PF00917	0.692
DOC_USP7_MATH_1	267	271	PF00917	0.495
DOC_USP7_MATH_1	301	305	PF00917	0.574
DOC_USP7_MATH_1	321	325	PF00917	0.368
DOC_USP7_MATH_1	393	397	PF00917	0.470
DOC_USP7_MATH_1	489	493	PF00917	0.509
DOC_USP7_MATH_1	639	643	PF00917	0.632
DOC_USP7_MATH_1	645	649	PF00917	0.678
DOC_USP7_MATH_1	659	663	PF00917	0.708
DOC_USP7_MATH_1	683	687	PF00917	0.668
DOC_USP7_MATH_1	768	772	PF00917	0.571
DOC_USP7_MATH_1	773	777	PF00917	0.556
DOC_USP7_MATH_1	830	834	PF00917	0.767
DOC_USP7_MATH_1	835	839	PF00917	0.696
DOC_USP7_MATH_1	844	848	PF00917	0.650
DOC_USP7_MATH_1	875	879	PF00917	0.562
DOC_USP7_MATH_1	921	925	PF00917	0.702
DOC_USP7_MATH_2	369	375	PF00917	0.501
DOC_USP7_UBL2_3	237	241	PF12436	0.543
DOC_USP7_UBL2_3	410	414	PF12436	0.474
DOC_WW_Pin1_4	1054	1059	PF00397	0.786
DOC_WW_Pin1_4	1077	1082	PF00397	0.734
DOC_WW_Pin1_4	317	322	PF00397	0.483
DOC_WW_Pin1_4	45	50	PF00397	0.471
DOC_WW_Pin1_4	509	514	PF00397	0.501
DOC_WW_Pin1_4	641	646	PF00397	0.671
DOC_WW_Pin1_4	679	684	PF00397	0.649
DOC_WW_Pin1_4	708	713	PF00397	0.686
DOC_WW_Pin1_4	725	730	PF00397	0.538
DOC_WW_Pin1_4	745	750	PF00397	0.660
DOC_WW_Pin1_4	791	796	PF00397	0.587
DOC_WW_Pin1_4	804	809	PF00397	0.608
DOC_WW_Pin1_4	863	868	PF00397	0.751
DOC_WW_Pin1_4	879	884	PF00397	0.504
LIG_14-3-3_CanoR_1	1064	1068	PF00244	0.714
LIG_14-3-3_CanoR_1	300	306	PF00244	0.495
LIG_14-3-3_CanoR_1	350	356	PF00244	0.497
LIG_14-3-3_CanoR_1	420	430	PF00244	0.560
LIG_14-3-3_CanoR_1	43	47	PF00244	0.524
LIG_14-3-3_CanoR_1	720	726	PF00244	0.665
LIG_14-3-3_CanoR_1	778	787	PF00244	0.734
LIG_14-3-3_CanoR_1	86	91	PF00244	0.332
LIG_14-3-3_CanoR_1	903	907	PF00244	0.617
LIG_Actin_WH2_2	259	277	PF00022	0.536
LIG_APCC_ABBA_1	752	757	PF00400	0.722
LIG_BIR_III_2	704	708	PF00653	0.651
LIG_BRCT_BRCA1_1	139	143	PF00533	0.399
LIG_BRCT_BRCA1_1	424	428	PF00533	0.422
LIG_deltaCOP1_diTrp_1	101	111	PF00928	0.512
LIG_deltaCOP1_diTrp_1	233	242	PF00928	0.470
LIG_FHA_1	1020	1026	PF00498	0.777
LIG_FHA_1	117	123	PF00498	0.553
LIG_FHA_1	527	533	PF00498	0.509
LIG_FHA_1	54	60	PF00498	0.491
LIG_FHA_1	610	616	PF00498	0.513
LIG_FHA_1	811	817	PF00498	0.674
LIG_FHA_1	856	862	PF00498	0.768
LIG_FHA_1	87	93	PF00498	0.636
LIG_FHA_1	874	880	PF00498	0.512
LIG_FHA_1	948	954	PF00498	0.725
LIG_FHA_1	992	998	PF00498	0.550
LIG_FHA_2	382	388	PF00498	0.470
LIG_FHA_2	403	409	PF00498	0.470
LIG_FHA_2	553	559	PF00498	0.495
LIG_FHA_2	614	620	PF00498	0.711
LIG_FHA_2	67	73	PF00498	0.459
LIG_FHA_2	697	703	PF00498	0.634
LIG_FHA_2	966	972	PF00498	0.689
LIG_FHA_2	983	989	PF00498	0.511
LIG_LIR_Apic_2	654	659	PF02991	0.674
LIG_LIR_Gen_1	238	247	PF02991	0.498
LIG_LIR_Gen_1	270	277	PF02991	0.521
LIG_LIR_Gen_1	328	338	PF02991	0.513
LIG_LIR_Gen_1	39	49	PF02991	0.525
LIG_LIR_Gen_1	504	513	PF02991	0.470
LIG_LIR_Gen_1	551	561	PF02991	0.536
LIG_LIR_Gen_1	85	95	PF02991	0.548
LIG_LIR_LC3C_4	760	764	PF02991	0.497
LIG_LIR_LC3C_4	847	850	PF02991	0.581
LIG_LIR_Nem_3	140	146	PF02991	0.404
LIG_LIR_Nem_3	172	178	PF02991	0.389
LIG_LIR_Nem_3	219	224	PF02991	0.470
LIG_LIR_Nem_3	238	242	PF02991	0.498
LIG_LIR_Nem_3	270	274	PF02991	0.508
LIG_LIR_Nem_3	328	333	PF02991	0.488
LIG_LIR_Nem_3	39	44	PF02991	0.415
LIG_LIR_Nem_3	504	508	PF02991	0.470
LIG_LIR_Nem_3	551	557	PF02991	0.536
LIG_LIR_Nem_3	593	599	PF02991	0.429
LIG_LIR_Nem_3	85	90	PF02991	0.554
LIG_MLH1_MIPbox_1	139	143	PF16413	0.399
LIG_MYND_1	338	342	PF01753	0.501
LIG_MYND_1	750	754	PF01753	0.711
LIG_MYND_2	749	753	PF01753	0.718
LIG_NRBOX	371	377	PF00104	0.536
LIG_Pex14_1	235	239	PF04695	0.547
LIG_Pex14_2	100	104	PF04695	0.408
LIG_Pex14_2	355	359	PF04695	0.495
LIG_PTB_Apo_2	276	283	PF02174	0.439
LIG_Rb_LxCxE_1	270	290	PF01857	0.498
LIG_SH2_CRK	118	122	PF00017	0.380
LIG_SH2_CRK	175	179	PF00017	0.430
LIG_SH2_CRK	271	275	PF00017	0.476
LIG_SH2_CRK	330	334	PF00017	0.495
LIG_SH2_CRK	401	405	PF00017	0.501
LIG_SH2_CRK	41	45	PF00017	0.494
LIG_SH2_NCK_1	31	35	PF00017	0.522
LIG_SH2_NCK_1	41	45	PF00017	0.494
LIG_SH2_PTP2	505	508	PF00017	0.470
LIG_SH2_SRC	11	14	PF00017	0.551
LIG_SH2_SRC	505	508	PF00017	0.495
LIG_SH2_STAP1	118	122	PF00017	0.368
LIG_SH2_STAP1	156	160	PF00017	0.482
LIG_SH2_STAT5	105	108	PF00017	0.434
LIG_SH2_STAT5	11	14	PF00017	0.494
LIG_SH2_STAT5	118	121	PF00017	0.373
LIG_SH2_STAT5	142	145	PF00017	0.454
LIG_SH2_STAT5	21	24	PF00017	0.387
LIG_SH2_STAT5	292	295	PF00017	0.478
LIG_SH2_STAT5	351	354	PF00017	0.470
LIG_SH2_STAT5	403	406	PF00017	0.478
LIG_SH2_STAT5	41	44	PF00017	0.253
LIG_SH2_STAT5	462	465	PF00017	0.373
LIG_SH2_STAT5	505	508	PF00017	0.470
LIG_SH2_STAT5	584	587	PF00017	0.357
LIG_SH3_1	877	883	PF00018	0.510
LIG_SH3_2	872	877	PF14604	0.591
LIG_SH3_3	1013	1019	PF00018	0.779
LIG_SH3_3	1075	1081	PF00018	0.729
LIG_SH3_3	222	228	PF00018	0.548
LIG_SH3_3	46	52	PF00018	0.489
LIG_SH3_3	493	499	PF00018	0.472
LIG_SH3_3	591	597	PF00018	0.427
LIG_SH3_3	709	715	PF00018	0.671
LIG_SH3_3	743	749	PF00018	0.602
LIG_SH3_3	789	795	PF00018	0.717
LIG_SH3_3	800	806	PF00018	0.727
LIG_SH3_3	859	865	PF00018	0.697
LIG_SH3_3	869	875	PF00018	0.662
LIG_SH3_3	877	883	PF00018	0.563
LIG_SH3_3	896	902	PF00018	0.533
LIG_SH3_3	935	941	PF00018	0.700
LIG_SH3_3	942	948	PF00018	0.754
LIG_SH3_3	950	956	PF00018	0.728
LIG_SUMO_SIM_anti_2	492	498	PF11976	0.387
LIG_SUMO_SIM_anti_2	531	536	PF11976	0.536
LIG_SUMO_SIM_anti_2	722	728	PF11976	0.537
LIG_SUMO_SIM_anti_2	813	818	PF11976	0.716
LIG_SUMO_SIM_par_1	283	290	PF11976	0.470
LIG_SUMO_SIM_par_1	313	318	PF11976	0.454
LIG_SUMO_SIM_par_1	529	536	PF11976	0.536
LIG_SUMO_SIM_par_1	706	711	PF11976	0.682
LIG_SUMO_SIM_par_1	812	818	PF11976	0.526
LIG_SUMO_SIM_par_1	847	853	PF11976	0.640
LIG_TRAF2_1	134	137	PF00917	0.472
LIG_TRAF2_1	678	681	PF00917	0.664
LIG_TRAF2_2	153	158	PF00917	0.497
LIG_TRAF2_2	499	504	PF00917	0.478
LIG_TRFH_1	31	35	PF08558	0.464
LIG_TYR_ITIM	269	274	PF00017	0.472
LIG_TYR_ITIM	399	404	PF00017	0.470
LIG_TYR_ITIM	503	508	PF00017	0.470
LIG_UBA3_1	399	407	PF00899	0.536
LIG_WRC_WIRS_1	138	143	PF05994	0.396
LIG_WW_3	900	904	PF00397	0.616
MOD_CDK_SPK_2	679	684	PF00069	0.711
MOD_CDK_SPK_2	804	809	PF00069	0.739
MOD_CK1_1	1040	1046	PF00069	0.727
MOD_CK1_1	1047	1053	PF00069	0.694
MOD_CK1_1	1054	1060	PF00069	0.633
MOD_CK1_1	270	276	PF00069	0.507
MOD_CK1_1	422	428	PF00069	0.618
MOD_CK1_1	509	515	PF00069	0.536
MOD_CK1_1	536	542	PF00069	0.501
MOD_CK1_1	613	619	PF00069	0.648
MOD_CK1_1	643	649	PF00069	0.689
MOD_CK1_1	686	692	PF00069	0.696
MOD_CK1_1	771	777	PF00069	0.691
MOD_CK1_1	782	788	PF00069	0.643
MOD_CK1_1	797	803	PF00069	0.800
MOD_CK1_1	810	816	PF00069	0.715
MOD_CK1_1	825	831	PF00069	0.614
MOD_CK1_1	85	91	PF00069	0.452
MOD_CK1_1	878	884	PF00069	0.637
MOD_CK1_1	924	930	PF00069	0.748
MOD_CK1_1	975	981	PF00069	0.690
MOD_CK2_1	227	233	PF00069	0.495
MOD_CK2_1	381	387	PF00069	0.476
MOD_CK2_1	402	408	PF00069	0.470
MOD_CK2_1	489	495	PF00069	0.543
MOD_CK2_1	613	619	PF00069	0.640
MOD_CK2_1	675	681	PF00069	0.652
MOD_CK2_1	696	702	PF00069	0.637
MOD_CK2_1	830	836	PF00069	0.681
MOD_CK2_1	95	101	PF00069	0.601
MOD_CK2_1	965	971	PF00069	0.688
MOD_GlcNHglycan	1046	1049	PF01048	0.736
MOD_GlcNHglycan	1053	1056	PF01048	0.733
MOD_GlcNHglycan	1060	1063	PF01048	0.702
MOD_GlcNHglycan	1074	1077	PF01048	0.821
MOD_GlcNHglycan	317	320	PF01048	0.279
MOD_GlcNHglycan	463	466	PF01048	0.461
MOD_GlcNHglycan	472	475	PF01048	0.336
MOD_GlcNHglycan	491	494	PF01048	0.336
MOD_GlcNHglycan	508	511	PF01048	0.226
MOD_GlcNHglycan	539	542	PF01048	0.348
MOD_GlcNHglycan	685	688	PF01048	0.546
MOD_GlcNHglycan	730	733	PF01048	0.607
MOD_GlcNHglycan	737	740	PF01048	0.615
MOD_GlcNHglycan	765	768	PF01048	0.788
MOD_GlcNHglycan	773	776	PF01048	0.737
MOD_GlcNHglycan	781	784	PF01048	0.604
MOD_GlcNHglycan	827	830	PF01048	0.542
MOD_GlcNHglycan	832	835	PF01048	0.707
MOD_GlcNHglycan	839	842	PF01048	0.595
MOD_GlcNHglycan	894	897	PF01048	0.634
MOD_GlcNHglycan	974	977	PF01048	0.737
MOD_GlcNHglycan	985	988	PF01048	0.724
MOD_GSK3_1	1037	1044	PF00069	0.749
MOD_GSK3_1	1047	1054	PF00069	0.724
MOD_GSK3_1	1072	1079	PF00069	0.815
MOD_GSK3_1	317	324	PF00069	0.476
MOD_GSK3_1	336	343	PF00069	0.444
MOD_GSK3_1	387	394	PF00069	0.501
MOD_GSK3_1	419	426	PF00069	0.577
MOD_GSK3_1	533	540	PF00069	0.521
MOD_GSK3_1	544	551	PF00069	0.536
MOD_GSK3_1	609	616	PF00069	0.633
MOD_GSK3_1	637	644	PF00069	0.650
MOD_GSK3_1	645	652	PF00069	0.587
MOD_GSK3_1	675	682	PF00069	0.677
MOD_GSK3_1	686	693	PF00069	0.641
MOD_GSK3_1	721	728	PF00069	0.644
MOD_GSK3_1	733	740	PF00069	0.639
MOD_GSK3_1	741	748	PF00069	0.481
MOD_GSK3_1	782	789	PF00069	0.645
MOD_GSK3_1	791	798	PF00069	0.520
MOD_GSK3_1	82	89	PF00069	0.575
MOD_GSK3_1	821	828	PF00069	0.630
MOD_GSK3_1	850	857	PF00069	0.654
MOD_GSK3_1	875	882	PF00069	0.601
MOD_GSK3_1	905	912	PF00069	0.798
MOD_GSK3_1	917	924	PF00069	0.798
MOD_GSK3_1	926	933	PF00069	0.782
MOD_GSK3_1	967	974	PF00069	0.719
MOD_N-GLC_1	1072	1077	PF02516	0.571
MOD_N-GLC_1	544	549	PF02516	0.270
MOD_N-GLC_1	613	618	PF02516	0.571
MOD_N-GLC_1	771	776	PF02516	0.724
MOD_N-GLC_1	976	981	PF02516	0.699
MOD_N-GLC_1	982	987	PF02516	0.742
MOD_NEK2_1	103	108	PF00069	0.456
MOD_NEK2_1	1037	1042	PF00069	0.718
MOD_NEK2_1	204	209	PF00069	0.483
MOD_NEK2_1	287	292	PF00069	0.517
MOD_NEK2_1	419	424	PF00069	0.524
MOD_NEK2_1	53	58	PF00069	0.535
MOD_NEK2_1	537	542	PF00069	0.523
MOD_NEK2_1	598	603	PF00069	0.414
MOD_NEK2_1	609	614	PF00069	0.477
MOD_NEK2_1	721	726	PF00069	0.610
MOD_NEK2_1	733	738	PF00069	0.569
MOD_NEK2_1	762	767	PF00069	0.717
MOD_NEK2_1	799	804	PF00069	0.619
MOD_NEK2_1	820	825	PF00069	0.669
MOD_NEK2_1	852	857	PF00069	0.635
MOD_NEK2_1	890	895	PF00069	0.699
MOD_NEK2_1	907	912	PF00069	0.560
MOD_NEK2_1	917	922	PF00069	0.707
MOD_NEK2_1	926	931	PF00069	0.682
MOD_NEK2_1	95	100	PF00069	0.491
MOD_NEK2_2	1063	1068	PF00069	0.719
MOD_NEK2_2	301	306	PF00069	0.545
MOD_NEK2_2	902	907	PF00069	0.611
MOD_PIKK_1	1024	1030	PF00454	0.722
MOD_PIKK_1	1047	1053	PF00454	0.614
MOD_PIKK_1	342	348	PF00454	0.427
MOD_PIKK_1	645	651	PF00454	0.666
MOD_PIKK_1	659	665	PF00454	0.605
MOD_PIKK_1	686	692	PF00454	0.660
MOD_PIKK_1	713	719	PF00454	0.655
MOD_PIKK_1	855	861	PF00454	0.722
MOD_PIKK_1	911	917	PF00454	0.580
MOD_PIKK_1	95	101	PF00454	0.459
MOD_PKA_2	1063	1069	PF00069	0.709
MOD_PKA_2	308	314	PF00069	0.511
MOD_PKA_2	381	387	PF00069	0.470
MOD_PKA_2	419	425	PF00069	0.515
MOD_PKA_2	42	48	PF00069	0.531
MOD_PKA_2	683	689	PF00069	0.707
MOD_PKA_2	719	725	PF00069	0.521
MOD_PKA_2	779	785	PF00069	0.790
MOD_PKA_2	820	826	PF00069	0.633
MOD_PKA_2	85	91	PF00069	0.335
MOD_PKA_2	902	908	PF00069	0.607
MOD_PKB_1	965	973	PF00069	0.619
MOD_Plk_1	287	293	PF00069	0.470
MOD_Plk_1	82	88	PF00069	0.557
MOD_Plk_4	137	143	PF00069	0.412
MOD_Plk_4	227	233	PF00069	0.482
MOD_Plk_4	336	342	PF00069	0.595
MOD_Plk_4	351	357	PF00069	0.486
MOD_Plk_4	371	377	PF00069	0.536
MOD_Plk_4	424	430	PF00069	0.522
MOD_Plk_4	548	554	PF00069	0.513
MOD_Plk_4	590	596	PF00069	0.379
MOD_Plk_4	721	727	PF00069	0.630
MOD_Plk_4	844	850	PF00069	0.617
MOD_ProDKin_1	1054	1060	PF00069	0.786
MOD_ProDKin_1	1077	1083	PF00069	0.731
MOD_ProDKin_1	317	323	PF00069	0.483
MOD_ProDKin_1	45	51	PF00069	0.468
MOD_ProDKin_1	509	515	PF00069	0.501
MOD_ProDKin_1	641	647	PF00069	0.672
MOD_ProDKin_1	679	685	PF00069	0.651
MOD_ProDKin_1	708	714	PF00069	0.685
MOD_ProDKin_1	725	731	PF00069	0.538
MOD_ProDKin_1	745	751	PF00069	0.654
MOD_ProDKin_1	791	797	PF00069	0.590
MOD_ProDKin_1	804	810	PF00069	0.609
MOD_ProDKin_1	863	869	PF00069	0.755
MOD_ProDKin_1	879	885	PF00069	0.507
MOD_SUMO_rev_2	14	19	PF00179	0.575
MOD_SUMO_rev_2	406	412	PF00179	0.536
TRG_DiLeu_BaEn_1	220	225	PF01217	0.470
TRG_DiLeu_BaEn_1	371	376	PF01217	0.495
TRG_DiLeu_BaLyEn_6	594	599	PF01217	0.436
TRG_DiLeu_BaLyEn_6	704	709	PF01217	0.733
TRG_DiLeu_BaLyEn_6	748	753	PF01217	0.589
TRG_ENDOCYTIC_2	118	121	PF00928	0.373
TRG_ENDOCYTIC_2	175	178	PF00928	0.426
TRG_ENDOCYTIC_2	271	274	PF00928	0.483
TRG_ENDOCYTIC_2	330	333	PF00928	0.470
TRG_ENDOCYTIC_2	401	404	PF00928	0.474
TRG_ENDOCYTIC_2	41	44	PF00928	0.490
TRG_ENDOCYTIC_2	505	508	PF00928	0.470
TRG_ER_diArg_1	1063	1065	PF00400	0.704
TRG_ER_diArg_1	27	30	PF00400	0.505
TRG_ER_diArg_1	312	314	PF00400	0.478
TRG_ER_diArg_1	381	383	PF00400	0.483
TRG_ER_diArg_1	419	421	PF00400	0.511
TRG_ER_diArg_1	497	500	PF00400	0.521
TRG_ER_diArg_1	666	668	PF00400	0.515
TRG_ER_diArg_1	778	781	PF00400	0.684
TRG_ER_diArg_1	902	904	PF00400	0.605
TRG_NLS_MonoCore_2	963	968	PF00514	0.732
TRG_NLS_MonoExtC_3	963	969	PF00514	0.703
TRG_Pf-PMV_PEXEL_1	150	155	PF00026	0.486
TRG_Pf-PMV_PEXEL_1	386	391	PF00026	0.294

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I1Z2	Leptomonas seymouri	61%	93%
A0A3Q8IC06	Leishmania donovani	89%	99%
A0A3R7MWL4	Trypanosoma rangeli	53%	100%
A4H349	Leishmania braziliensis	22%	100%
A4HDB9	Leishmania braziliensis	76%	98%
A4I0P9	Leishmania infantum	89%	99%
D0A725	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	100%
Q4QAS2	Leishmania major	84%	94%