LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AWP7_LEIMU
TriTrypDb:
LmxM.24.0555
Length:
88

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0016020 membrane 2 6
GO:0110165 cellular anatomical entity 1 6

Expansion

Sequence features

E9AWP7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AWP7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 42 44 PF00675 0.448
CLV_PCSK_KEX2_1 42 44 PF00082 0.448
CLV_PCSK_PC7_1 38 44 PF00082 0.434
DEG_Nend_UBRbox_2 1 3 PF02207 0.410
LIG_CaM_IQ_9 30 46 PF13499 0.494
LIG_FHA_1 11 17 PF00498 0.405
LIG_LIR_Gen_1 4 14 PF02991 0.399
LIG_LIR_Nem_3 4 9 PF02991 0.494
LIG_SUMO_SIM_par_1 18 23 PF11976 0.383
MOD_CK1_1 28 34 PF00069 0.290
MOD_CK1_1 81 87 PF00069 0.749
MOD_CK2_1 49 55 PF00069 0.614
MOD_Cter_Amidation 40 43 PF01082 0.329
MOD_GSK3_1 77 84 PF00069 0.658
MOD_N-GLC_1 67 72 PF02516 0.522
MOD_N-GLC_1 81 86 PF02516 0.397
MOD_NEK2_1 49 54 PF00069 0.615
MOD_NEK2_1 8 13 PF00069 0.366
MOD_Plk_1 81 87 PF00069 0.677
MOD_Plk_4 20 26 PF00069 0.304

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HZK7 Leptomonas seymouri 41% 96%
A0A3S7WY55 Leishmania donovani 86% 96%
A4HDB5 Leishmania braziliensis 57% 100%
E9ACS8 Leishmania major 88% 100%
E9AH56 Leishmania infantum 88% 96%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS