Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AWJ3_LEIMU

TriTrypDb:

LmxM.24.0030

Length:

166

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AWJ3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AWJ3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	106	108	PF00675	0.419
CLV_NRD_NRD_1	129	131	PF00675	0.540
CLV_NRD_NRD_1	144	146	PF00675	0.516
CLV_NRD_NRD_1	164	166	PF00675	0.738
CLV_NRD_NRD_1	46	48	PF00675	0.643
CLV_PCSK_KEX2_1	137	139	PF00082	0.560
CLV_PCSK_KEX2_1	46	48	PF00082	0.643
CLV_PCSK_PC1ET2_1	137	139	PF00082	0.556
CLV_PCSK_SKI1_1	58	62	PF00082	0.473
CLV_PCSK_SKI1_1	84	88	PF00082	0.436
DEG_APCC_KENBOX_2	107	111	PF00400	0.426
DEG_Nend_UBRbox_1	1	4	PF02207	0.499
DOC_MAPK_gen_1	107	114	PF00069	0.444
DOC_MAPK_gen_1	65	72	PF00069	0.290
DOC_USP7_MATH_1	113	117	PF00917	0.296
DOC_USP7_MATH_1	95	99	PF00917	0.503
DOC_USP7_UBL2_3	133	137	PF12436	0.490
DOC_WW_Pin1_4	147	152	PF00397	0.493
DOC_WW_Pin1_4	154	159	PF00397	0.558
LIG_14-3-3_CanoR_1	152	157	PF00244	0.660
LIG_14-3-3_CanoR_1	58	66	PF00244	0.514
LIG_14-3-3_CanoR_1	74	80	PF00244	0.281
LIG_BRCT_BRCA1_1	100	104	PF00533	0.434
LIG_FHA_2	76	82	PF00498	0.292
LIG_LIR_Nem_3	101	106	PF02991	0.396
LIG_LIR_Nem_3	61	66	PF02991	0.437
LIG_LIR_Nem_3	68	72	PF02991	0.383
LIG_MLH1_MIPbox_1	100	104	PF16413	0.408
LIG_REV1ctd_RIR_1	101	112	PF16727	0.402
LIG_SH2_CRK	90	94	PF00017	0.469
LIG_SH2_STAT3	21	24	PF00017	0.599
LIG_SH3_1	47	53	PF00018	0.537
LIG_SH3_2	41	46	PF14604	0.590
LIG_SH3_3	38	44	PF00018	0.596
LIG_SH3_3	47	53	PF00018	0.425
LIG_TYR_ITIM	88	93	PF00017	0.488
LIG_WRC_WIRS_1	66	71	PF05994	0.429
LIG_WW_3	162	166	PF00397	0.640
MOD_CDC14_SPxK_1	157	160	PF00782	0.512
MOD_CDK_SPK_2	147	152	PF00069	0.443
MOD_CDK_SPxK_1	154	160	PF00069	0.511
MOD_CDK_SPxxK_3	147	154	PF00069	0.449
MOD_CK1_1	98	104	PF00069	0.452
MOD_DYRK1A_RPxSP_1	154	158	PF00069	0.569
MOD_GlcNHglycan	117	120	PF01048	0.479
MOD_GlcNHglycan	97	100	PF01048	0.537
MOD_GSK3_1	152	159	PF00069	0.666
MOD_N-GLC_1	147	152	PF02516	0.443
MOD_PIKK_1	140	146	PF00454	0.404
MOD_Plk_4	65	71	PF00069	0.475
MOD_ProDKin_1	147	153	PF00069	0.495
MOD_ProDKin_1	154	160	PF00069	0.561
MOD_SUMO_rev_2	129	139	PF00179	0.575
TRG_DiLeu_BaLyEn_6	55	60	PF01217	0.454
TRG_ENDOCYTIC_2	90	93	PF00928	0.473
TRG_ER_diArg_1	151	154	PF00400	0.534

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0NIP0	Trypanosomatidae	47%	98%
A0A3S7WXZ3	Leishmania donovani	88%	100%
A0A422P424	Trypanosoma rangeli	42%	100%
A4HD61	Leishmania braziliensis	80%	100%
A4I0M6	Leishmania infantum	88%	100%
D0A6X4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	47%	95%
Q4QAX7	Leishmania major	88%	100%