YceI domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

YceI-like domain containing protein, putative

Species:

Leishmania mexicana

UniProt:

E9AWF2_LEIMU

TriTrypDb:

LmxM.23.1320

Length:

189

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AWF2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AWF2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	10	12	PF00675	0.336
CLV_NRD_NRD_1	54	56	PF00675	0.440
CLV_PCSK_KEX2_1	10	12	PF00082	0.503
CLV_PCSK_KEX2_1	54	56	PF00082	0.504
CLV_PCSK_SKI1_1	185	189	PF00082	0.506
DOC_CYCLIN_yCln2_LP_2	37	43	PF00134	0.414
DOC_MAPK_gen_1	80	88	PF00069	0.391
DOC_MAPK_gen_1	97	105	PF00069	0.297
DOC_MAPK_JIP1_4	39	45	PF00069	0.264
DOC_MAPK_MEF2A_6	19	27	PF00069	0.459
DOC_MAPK_MEF2A_6	80	88	PF00069	0.418
DOC_MAPK_RevD_3	41	55	PF00069	0.273
DOC_PP4_FxxP_1	158	161	PF00568	0.316
DOC_USP7_MATH_1	117	121	PF00917	0.459
LIG_14-3-3_CanoR_1	10	18	PF00244	0.440
LIG_14-3-3_CanoR_1	133	137	PF00244	0.330
LIG_14-3-3_CanoR_1	154	162	PF00244	0.404
LIG_14-3-3_CanoR_1	97	102	PF00244	0.340
LIG_APCC_ABBA_1	23	28	PF00400	0.380
LIG_BIR_II_1	1	5	PF00653	0.525
LIG_FHA_1	110	116	PF00498	0.420
LIG_FHA_1	124	130	PF00498	0.305
LIG_FHA_1	173	179	PF00498	0.414
LIG_FHA_2	169	175	PF00498	0.449
LIG_LIR_Apic_2	156	161	PF02991	0.356
LIG_LIR_Gen_1	22	32	PF02991	0.507
LIG_LIR_Gen_1	79	88	PF02991	0.497
LIG_LIR_LC3C_4	146	149	PF02991	0.393
LIG_LIR_Nem_3	106	111	PF02991	0.391
LIG_LIR_Nem_3	22	27	PF02991	0.476
LIG_LIR_Nem_3	79	84	PF02991	0.484
LIG_LYPXL_yS_3	108	111	PF13949	0.378
LIG_PDZ_Class_2	184	189	PF00595	0.440
LIG_Pex14_1	166	170	PF04695	0.580
LIG_RPA_C_Fungi	50	62	PF08784	0.381
LIG_SH2_PTP2	24	27	PF00017	0.440
LIG_SH2_SRC	24	27	PF00017	0.440
LIG_SH2_STAP1	113	117	PF00017	0.526
LIG_SH2_STAT5	101	104	PF00017	0.374
LIG_SH2_STAT5	24	27	PF00017	0.358
LIG_SH3_3	146	152	PF00018	0.333
LIG_SH3_3	72	78	PF00018	0.479
LIG_SUMO_SIM_par_1	174	180	PF11976	0.384
MOD_CK1_1	13	19	PF00069	0.428
MOD_CK2_1	11	17	PF00069	0.415
MOD_CK2_1	76	82	PF00069	0.505
MOD_CK2_1	86	92	PF00069	0.389
MOD_GSK3_1	132	139	PF00069	0.452
MOD_GSK3_1	168	175	PF00069	0.469
MOD_N-GLC_1	103	108	PF02516	0.253
MOD_N-GLC_1	117	122	PF02516	0.371
MOD_N-GLC_1	86	91	PF02516	0.270
MOD_NEK2_1	103	108	PF00069	0.405
MOD_NEK2_1	95	100	PF00069	0.487
MOD_PIKK_1	153	159	PF00454	0.409
MOD_PIKK_1	168	174	PF00454	0.340
MOD_PKA_1	10	16	PF00069	0.483
MOD_PKA_2	10	16	PF00069	0.392
MOD_PKA_2	132	138	PF00069	0.462
MOD_PKA_2	153	159	PF00069	0.542
MOD_Plk_1	103	109	PF00069	0.267
MOD_Plk_4	65	71	PF00069	0.457
MOD_SUMO_rev_2	13	21	PF00179	0.494
TRG_DiLeu_BaEn_1	143	148	PF01217	0.349
TRG_DiLeu_BaEn_1	28	33	PF01217	0.455
TRG_DiLeu_BaLyEn_6	106	111	PF01217	0.482
TRG_ENDOCYTIC_2	108	111	PF00928	0.378
TRG_ENDOCYTIC_2	24	27	PF00928	0.474
TRG_ER_diArg_1	10	12	PF00400	0.264
TRG_NES_CRM1_1	17	28	PF08389	0.464

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I2D1	Leptomonas seymouri	74%	100%
A0A0S4ITC1	Bodo saltans	42%	98%
A0A1X0NXE1	Trypanosomatidae	52%	100%
A0A3Q8IBN7	Leishmania donovani	93%	100%
A0A3R7LAA8	Trypanosoma rangeli	51%	100%
A4HD05	Leishmania braziliensis	88%	100%
A4I0J0	Leishmania infantum	93%	100%
C9ZVB6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	97%
Q4QB20	Leishmania major	89%	100%