Non-specific serine/threonine protein kinase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AWE9_LEIMU

TriTrypDb:

LmxM.23.1290

Length:

673

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5

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Expansion

Sequence features

E9AWE9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AWE9

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	102	106	PF00656	0.673
CLV_C14_Caspase3-7	24	28	PF00656	0.626
CLV_C14_Caspase3-7	295	299	PF00656	0.739
CLV_C14_Caspase3-7	536	540	PF00656	0.731
CLV_MEL_PAP_1	46	52	PF00089	0.453
CLV_NRD_NRD_1	130	132	PF00675	0.608
CLV_NRD_NRD_1	173	175	PF00675	0.443
CLV_NRD_NRD_1	20	22	PF00675	0.575
CLV_NRD_NRD_1	31	33	PF00675	0.497
CLV_NRD_NRD_1	345	347	PF00675	0.549

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IFX5	Leishmania donovani	76%	98%
A4HD02	Leishmania braziliensis	49%	99%
A4I0I7	Leishmania infantum	76%	98%
Q4QB23	Leishmania major	76%	100%

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