Exonuclease 1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Exonuclease 1

Gene product:

XPG N-terminal domain/XPG I-region, putative

Species:

Leishmania mexicana

UniProt:

E9AWE7_LEIMU

TriTrypDb:

LmxM.23.1270

Length:

1013

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	7
GO:0043226	organelle	2	7
GO:0043227	membrane-bounded organelle	3	7
GO:0043229	intracellular organelle	3	7
GO:0043231	intracellular membrane-bounded organelle	4	7
GO:0110165	cellular anatomical entity	1	7

Expansion

Sequence features

E9AWE7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AWE7

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006259	DNA metabolic process	4	7
GO:0006281	DNA repair	5	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0006950	response to stress	2	7
GO:0006974	DNA damage response	4	7
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0033554	cellular response to stress	3	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0043170	macromolecule metabolic process	3	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044260	obsolete cellular macromolecule metabolic process	3	7
GO:0046483	heterocycle metabolic process	3	7
GO:0050896	response to stimulus	1	7
GO:0051716	cellular response to stimulus	2	7
GO:0071704	organic substance metabolic process	2	7
GO:0090304	nucleic acid metabolic process	4	7
GO:1901360	organic cyclic compound metabolic process	3	7

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003677	DNA binding	4	7
GO:0003824	catalytic activity	1	7
GO:0004518	nuclease activity	4	7
GO:0004527	exonuclease activity	5	7
GO:0004529	DNA exonuclease activity	5	7
GO:0004536	DNA nuclease activity	4	7
GO:0005488	binding	1	7
GO:0008409	5'-3' exonuclease activity	6	7
GO:0016787	hydrolase activity	2	7
GO:0016788	hydrolase activity, acting on ester bonds	3	7
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6	7
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	6	7
GO:0035312	5'-3' DNA exonuclease activity	7	7
GO:0043167	ion binding	2	7
GO:0043169	cation binding	3	7
GO:0046872	metal ion binding	4	7
GO:0097159	organic cyclic compound binding	2	7
GO:0140097	catalytic activity, acting on DNA	3	7
GO:0140640	catalytic activity, acting on a nucleic acid	2	7
GO:1901363	heterocyclic compound binding	2	7
GO:0004519	endonuclease activity	5	1
GO:0004520	DNA endonuclease activity	5	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	6	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6	1
GO:0017108	5'-flap endonuclease activity	7	1
GO:0048256	flap endonuclease activity	6	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	613	617	PF00656	0.701
CLV_C14_Caspase3-7	619	623	PF00656	0.663
CLV_C14_Caspase3-7	708	712	PF00656	0.592
CLV_C14_Caspase3-7	72	76	PF00656	0.531
CLV_C14_Caspase3-7	754	758	PF00656	0.621
CLV_C14_Caspase3-7	760	764	PF00656	0.605
CLV_C14_Caspase3-7	876	880	PF00656	0.540
CLV_NRD_NRD_1	139	141	PF00675	0.273
CLV_NRD_NRD_1	159	161	PF00675	0.435
CLV_NRD_NRD_1	280	282	PF00675	0.520
CLV_NRD_NRD_1	304	306	PF00675	0.728
CLV_NRD_NRD_1	316	318	PF00675	0.535
CLV_NRD_NRD_1	423	425	PF00675	0.428
CLV_NRD_NRD_1	513	515	PF00675	0.468
CLV_NRD_NRD_1	541	543	PF00675	0.625
CLV_NRD_NRD_1	634	636	PF00675	0.535
CLV_NRD_NRD_1	834	836	PF00675	0.453
CLV_PCSK_FUR_1	136	140	PF00082	0.273
CLV_PCSK_FUR_1	511	515	PF00082	0.455
CLV_PCSK_KEX2_1	138	140	PF00082	0.273
CLV_PCSK_KEX2_1	159	161	PF00082	0.437
CLV_PCSK_KEX2_1	280	282	PF00082	0.520
CLV_PCSK_KEX2_1	304	306	PF00082	0.728
CLV_PCSK_KEX2_1	316	318	PF00082	0.535
CLV_PCSK_KEX2_1	423	425	PF00082	0.423
CLV_PCSK_KEX2_1	513	515	PF00082	0.468
CLV_PCSK_KEX2_1	541	543	PF00082	0.625
CLV_PCSK_KEX2_1	634	636	PF00082	0.535
CLV_PCSK_SKI1_1	1007	1011	PF00082	0.597
CLV_PCSK_SKI1_1	298	302	PF00082	0.618
CLV_PCSK_SKI1_1	392	396	PF00082	0.384
CLV_PCSK_SKI1_1	781	785	PF00082	0.432
DEG_APCC_DBOX_1	780	788	PF00400	0.562
DEG_SCF_FBW7_2	790	797	PF00400	0.502
DEG_SCF_TRCP1_1	711	716	PF00400	0.527
DEG_SPOP_SBC_1	578	582	PF00917	0.702
DEG_SPOP_SBC_1	689	693	PF00917	0.505
DOC_CYCLIN_RxL_1	1004	1013	PF00134	0.579
DOC_CYCLIN_yCln2_LP_2	269	275	PF00134	0.454
DOC_MAPK_DCC_7	112	120	PF00069	0.473
DOC_MAPK_FxFP_2	415	418	PF00069	0.483
DOC_MAPK_gen_1	23	33	PF00069	0.473
DOC_MAPK_gen_1	44	53	PF00069	0.456
DOC_MAPK_gen_1	539	547	PF00069	0.499
DOC_MAPK_MEF2A_6	112	120	PF00069	0.524
DOC_MAPK_MEF2A_6	23	31	PF00069	0.473
DOC_PP2B_LxvP_1	269	272	PF13499	0.447
DOC_PP2B_LxvP_1	273	276	PF13499	0.426
DOC_PP4_FxxP_1	415	418	PF00568	0.483
DOC_PP4_FxxP_1	557	560	PF00568	0.605
DOC_PP4_FxxP_1	913	916	PF00568	0.590
DOC_SPAK_OSR1_1	112	116	PF12202	0.473
DOC_USP7_MATH_1	178	182	PF00917	0.454
DOC_USP7_MATH_1	239	243	PF00917	0.473
DOC_USP7_MATH_1	283	287	PF00917	0.425
DOC_USP7_MATH_1	331	335	PF00917	0.664
DOC_USP7_MATH_1	338	342	PF00917	0.590
DOC_USP7_MATH_1	361	365	PF00917	0.543
DOC_USP7_MATH_1	454	458	PF00917	0.495
DOC_USP7_MATH_1	578	582	PF00917	0.702
DOC_USP7_MATH_1	654	658	PF00917	0.770
DOC_USP7_MATH_1	674	678	PF00917	0.629
DOC_USP7_MATH_1	738	742	PF00917	0.654
DOC_USP7_MATH_1	877	881	PF00917	0.768
DOC_USP7_MATH_1	920	924	PF00917	0.574
DOC_USP7_MATH_1	970	974	PF00917	0.616
DOC_USP7_MATH_1	984	988	PF00917	0.588
DOC_USP7_MATH_1	992	996	PF00917	0.621
DOC_USP7_MATH_1	998	1002	PF00917	0.714
DOC_USP7_UBL2_3	1007	1011	PF12436	0.571
DOC_USP7_UBL2_3	392	396	PF12436	0.384
DOC_WW_Pin1_4	440	445	PF00397	0.417
DOC_WW_Pin1_4	548	553	PF00397	0.634
DOC_WW_Pin1_4	58	63	PF00397	0.449
DOC_WW_Pin1_4	661	666	PF00397	0.588
DOC_WW_Pin1_4	679	684	PF00397	0.667
DOC_WW_Pin1_4	711	716	PF00397	0.725
DOC_WW_Pin1_4	78	83	PF00397	0.655
DOC_WW_Pin1_4	790	795	PF00397	0.495
DOC_WW_Pin1_4	817	822	PF00397	0.615
DOC_WW_Pin1_4	881	886	PF00397	0.663
DOC_WW_Pin1_4	888	893	PF00397	0.613
DOC_WW_Pin1_4	896	901	PF00397	0.580
DOC_WW_Pin1_4	930	935	PF00397	0.710
DOC_WW_Pin1_4	952	957	PF00397	0.584
DOC_WW_Pin1_4	966	971	PF00397	0.621
DOC_WW_Pin1_4	975	980	PF00397	0.619
LIG_14-3-3_CanoR_1	162	167	PF00244	0.450
LIG_14-3-3_CanoR_1	174	178	PF00244	0.535
LIG_14-3-3_CanoR_1	405	415	PF00244	0.471
LIG_14-3-3_CanoR_1	44	53	PF00244	0.456
LIG_14-3-3_CanoR_1	513	522	PF00244	0.512
LIG_14-3-3_CanoR_1	601	610	PF00244	0.595
LIG_14-3-3_CanoR_1	634	639	PF00244	0.646
LIG_14-3-3_CanoR_1	839	844	PF00244	0.512
LIG_APCC_ABBA_1	533	538	PF00400	0.658
LIG_APCC_ABBAyCdc20_2	532	538	PF00400	0.658
LIG_BIR_III_4	311	315	PF00653	0.589
LIG_BRCT_BRCA1_1	594	598	PF00533	0.582
LIG_CaM_IQ_9	506	522	PF13499	0.473
LIG_Clathr_ClatBox_1	148	152	PF01394	0.396
LIG_EH_1	652	656	PF12763	0.518
LIG_FHA_1	444	450	PF00498	0.466
LIG_FHA_1	45	51	PF00498	0.376
LIG_FHA_1	461	467	PF00498	0.485
LIG_FHA_1	491	497	PF00498	0.384
LIG_FHA_1	504	510	PF00498	0.396
LIG_FHA_1	695	701	PF00498	0.664
LIG_FHA_1	791	797	PF00498	0.606
LIG_FHA_1	798	804	PF00498	0.633
LIG_FHA_1	945	951	PF00498	0.522
LIG_FHA_2	130	136	PF00498	0.501
LIG_FHA_2	407	413	PF00498	0.407
LIG_FHA_2	613	619	PF00498	0.693
LIG_FHA_2	699	705	PF00498	0.660
LIG_FHA_2	712	718	PF00498	0.556
LIG_FHA_2	738	744	PF00498	0.490
LIG_FHA_2	943	949	PF00498	0.566
LIG_LIR_Apic_2	412	418	PF02991	0.418
LIG_LIR_Apic_2	556	560	PF02991	0.609
LIG_LIR_Gen_1	30	39	PF02991	0.473
LIG_LIR_Gen_1	367	376	PF02991	0.386
LIG_LIR_Gen_1	523	533	PF02991	0.586
LIG_LIR_Gen_1	96	107	PF02991	0.277
LIG_LIR_Nem_3	30	35	PF02991	0.473
LIG_LIR_Nem_3	367	371	PF02991	0.400
LIG_LIR_Nem_3	431	436	PF02991	0.350
LIG_LIR_Nem_3	451	455	PF02991	0.485
LIG_LIR_Nem_3	595	600	PF02991	0.650
LIG_LIR_Nem_3	96	102	PF02991	0.277
LIG_MLH1_MIPbox_1	594	598	PF16413	0.582
LIG_MYND_1	862	866	PF01753	0.616
LIG_PCNA_PIPBox_1	502	511	PF02747	0.403
LIG_PCNA_yPIPBox_3	498	509	PF02747	0.403
LIG_Pex14_2	844	848	PF04695	0.494
LIG_PROFILIN_1	859	865	PF00235	0.612
LIG_REV1ctd_RIR_1	276	285	PF16727	0.407
LIG_REV1ctd_RIR_1	51	61	PF16727	0.493
LIG_REV1ctd_RIR_1	595	605	PF16727	0.650
LIG_SH2_CRK	442	446	PF00017	0.365
LIG_SH2_CRK	452	456	PF00017	0.419
LIG_SH2_CRK	497	501	PF00017	0.404
LIG_SH2_PTP2	32	35	PF00017	0.473
LIG_SH2_SRC	184	187	PF00017	0.387
LIG_SH2_STAP1	184	188	PF00017	0.387
LIG_SH2_STAP1	222	226	PF00017	0.473
LIG_SH2_STAP1	368	372	PF00017	0.348
LIG_SH2_STAT5	13	16	PF00017	0.473
LIG_SH2_STAT5	155	158	PF00017	0.372
LIG_SH2_STAT5	164	167	PF00017	0.558
LIG_SH2_STAT5	230	233	PF00017	0.473
LIG_SH2_STAT5	236	239	PF00017	0.473
LIG_SH2_STAT5	251	254	PF00017	0.498
LIG_SH2_STAT5	32	35	PF00017	0.473
LIG_SH2_STAT5	382	385	PF00017	0.382
LIG_SH2_STAT5	434	437	PF00017	0.344
LIG_SH2_STAT5	508	511	PF00017	0.411
LIG_SH2_STAT5	522	525	PF00017	0.546
LIG_SH2_STAT5	908	911	PF00017	0.607
LIG_SH3_3	265	271	PF00018	0.514
LIG_SH3_3	438	444	PF00018	0.333
LIG_SH3_3	497	503	PF00018	0.467
LIG_SH3_3	627	633	PF00018	0.617
LIG_SH3_3	637	643	PF00018	0.667
LIG_SH3_3	659	665	PF00018	0.620
LIG_SH3_3	818	824	PF00018	0.676
LIG_SH3_3	856	862	PF00018	0.618
LIG_SH3_3	863	869	PF00018	0.630
LIG_SH3_3	886	892	PF00018	0.647
LIG_SH3_3	931	937	PF00018	0.652
LIG_SH3_3	973	979	PF00018	0.664
LIG_SH3_3	988	994	PF00018	0.609
LIG_Sin3_3	293	300	PF02671	0.562
LIG_SUMO_SIM_anti_2	90	97	PF11976	0.573
LIG_SUMO_SIM_par_1	589	595	PF11976	0.558
LIG_SUMO_SIM_par_1	90	97	PF11976	0.392
LIG_TRAF2_1	132	135	PF00917	0.473
LIG_TRAF2_1	701	704	PF00917	0.590
LIG_TYR_ITIM	440	445	PF00017	0.346
LIG_TYR_ITIM	450	455	PF00017	0.410
LIG_UBA3_1	1004	1012	PF00899	0.644
LIG_WRC_WIRS_1	259	264	PF05994	0.498
LIG_WRC_WIRS_1	368	373	PF05994	0.390
LIG_WW_2	862	865	PF00397	0.615
LIG_WW_2	991	994	PF00397	0.591
LIG_WW_3	824	828	PF00397	0.661
LIG_WW_3	914	918	PF00397	0.592
MOD_CDC14_SPxK_1	551	554	PF00782	0.622
MOD_CDK_SPxK_1	548	554	PF00069	0.632
MOD_CDK_SPxxK_3	888	895	PF00069	0.701
MOD_CDK_SPxxK_3	896	903	PF00069	0.595
MOD_CK1_1	173	179	PF00069	0.362
MOD_CK1_1	242	248	PF00069	0.473
MOD_CK1_1	364	370	PF00069	0.453
MOD_CK1_1	443	449	PF00069	0.525
MOD_CK1_1	457	463	PF00069	0.491
MOD_CK1_1	548	554	PF00069	0.637
MOD_CK1_1	580	586	PF00069	0.640
MOD_CK1_1	648	654	PF00069	0.532
MOD_CK1_1	664	670	PF00069	0.608
MOD_CK1_1	69	75	PF00069	0.526
MOD_CK1_1	694	700	PF00069	0.611
MOD_CK1_1	741	747	PF00069	0.586
MOD_CK1_1	751	757	PF00069	0.616
MOD_CK1_1	83	89	PF00069	0.382
MOD_CK1_1	881	887	PF00069	0.800
MOD_CK1_1	888	894	PF00069	0.631
MOD_CK1_1	896	902	PF00069	0.576
MOD_CK1_1	923	929	PF00069	0.587
MOD_CK1_1	930	936	PF00069	0.695
MOD_CK1_1	969	975	PF00069	0.647
MOD_CK1_1	977	983	PF00069	0.728
MOD_CK2_1	129	135	PF00069	0.472
MOD_CK2_1	406	412	PF00069	0.402
MOD_CK2_1	608	614	PF00069	0.628
MOD_CK2_1	698	704	PF00069	0.766
MOD_CK2_1	737	743	PF00069	0.495
MOD_CK2_1	839	845	PF00069	0.513
MOD_CK2_1	851	857	PF00069	0.587
MOD_CK2_1	942	948	PF00069	0.600
MOD_CK2_1	952	958	PF00069	0.607
MOD_DYRK1A_RPxSP_1	661	665	PF00069	0.672
MOD_GlcNHglycan	262	265	PF01048	0.273
MOD_GlcNHglycan	285	288	PF01048	0.480
MOD_GlcNHglycan	290	293	PF01048	0.499
MOD_GlcNHglycan	298	301	PF01048	0.515
MOD_GlcNHglycan	349	352	PF01048	0.552
MOD_GlcNHglycan	355	358	PF01048	0.599
MOD_GlcNHglycan	363	366	PF01048	0.514
MOD_GlcNHglycan	377	380	PF01048	0.345
MOD_GlcNHglycan	459	462	PF01048	0.479
MOD_GlcNHglycan	567	570	PF01048	0.609
MOD_GlcNHglycan	58	61	PF01048	0.424
MOD_GlcNHglycan	622	625	PF01048	0.730
MOD_GlcNHglycan	674	677	PF01048	0.691
MOD_GlcNHglycan	71	74	PF01048	0.556
MOD_GlcNHglycan	711	714	PF01048	0.535
MOD_GlcNHglycan	722	726	PF01048	0.505
MOD_GlcNHglycan	740	743	PF01048	0.650
MOD_GlcNHglycan	748	751	PF01048	0.572
MOD_GlcNHglycan	759	762	PF01048	0.495
MOD_GlcNHglycan	875	878	PF01048	0.715
MOD_GlcNHglycan	895	898	PF01048	0.671
MOD_GlcNHglycan	922	925	PF01048	0.705
MOD_GlcNHglycan	927	930	PF01048	0.697
MOD_GlcNHglycan	986	989	PF01048	0.613
MOD_GSK3_1	254	261	PF00069	0.473
MOD_GSK3_1	283	290	PF00069	0.467
MOD_GSK3_1	347	354	PF00069	0.543
MOD_GSK3_1	355	362	PF00069	0.562
MOD_GSK3_1	577	584	PF00069	0.637
MOD_GSK3_1	58	65	PF00069	0.529
MOD_GSK3_1	608	615	PF00069	0.637
MOD_GSK3_1	642	649	PF00069	0.662
MOD_GSK3_1	660	667	PF00069	0.579
MOD_GSK3_1	668	675	PF00069	0.647
MOD_GSK3_1	690	697	PF00069	0.663
MOD_GSK3_1	709	716	PF00069	0.515
MOD_GSK3_1	737	744	PF00069	0.548
MOD_GSK3_1	751	758	PF00069	0.658
MOD_GSK3_1	813	820	PF00069	0.700
MOD_GSK3_1	839	846	PF00069	0.511
MOD_GSK3_1	873	880	PF00069	0.771
MOD_GSK3_1	881	888	PF00069	0.570
MOD_GSK3_1	916	923	PF00069	0.604
MOD_GSK3_1	965	972	PF00069	0.651
MOD_N-GLC_1	645	650	PF02516	0.522
MOD_N-GLC_1	726	731	PF02516	0.637
MOD_N-GLC_2	786	788	PF02516	0.447
MOD_N-GLC_2	939	941	PF02516	0.600
MOD_NEK2_1	282	287	PF00069	0.431
MOD_NEK2_1	296	301	PF00069	0.637
MOD_NEK2_1	509	514	PF00069	0.507
MOD_NEK2_1	545	550	PF00069	0.533
MOD_NEK2_1	570	575	PF00069	0.688
MOD_NEK2_1	644	649	PF00069	0.779
MOD_NEK2_1	668	673	PF00069	0.768
MOD_NEK2_1	709	714	PF00069	0.552
MOD_NEK2_1	728	733	PF00069	0.649
MOD_NEK2_1	745	750	PF00069	0.525
MOD_NEK2_1	893	898	PF00069	0.701
MOD_NEK2_1	927	932	PF00069	0.566
MOD_NEK2_2	515	520	PF00069	0.519
MOD_PIKK_1	17	23	PF00454	0.473
MOD_PIKK_1	443	449	PF00454	0.457
MOD_PIKK_1	465	471	PF00454	0.464
MOD_PIKK_1	503	509	PF00454	0.464
MOD_PIKK_1	545	551	PF00454	0.685
MOD_PIKK_1	703	709	PF00454	0.607
MOD_PK_1	46	52	PF00069	0.433
MOD_PK_1	839	845	PF00069	0.513
MOD_PKA_1	634	640	PF00069	0.518
MOD_PKA_2	173	179	PF00069	0.539
MOD_PKA_2	634	640	PF00069	0.647
MOD_PKA_2	660	666	PF00069	0.681
MOD_PKA_2	755	761	PF00069	0.732
MOD_PKA_2	772	778	PF00069	0.483
MOD_PKA_2	916	922	PF00069	0.606
MOD_PKB_1	160	168	PF00069	0.524
MOD_PKB_1	44	52	PF00069	0.410
MOD_Plk_2-3	66	72	PF00069	0.603
MOD_Plk_2-3	797	803	PF00069	0.660
MOD_Plk_4	367	373	PF00069	0.373
MOD_Plk_4	46	52	PF00069	0.495
MOD_Plk_4	728	734	PF00069	0.692
MOD_Plk_4	741	747	PF00069	0.526
MOD_Plk_4	839	845	PF00069	0.513
MOD_Plk_4	970	976	PF00069	0.674
MOD_ProDKin_1	440	446	PF00069	0.426
MOD_ProDKin_1	548	554	PF00069	0.632
MOD_ProDKin_1	58	64	PF00069	0.459
MOD_ProDKin_1	661	667	PF00069	0.591
MOD_ProDKin_1	679	685	PF00069	0.530
MOD_ProDKin_1	711	717	PF00069	0.727
MOD_ProDKin_1	78	84	PF00069	0.647
MOD_ProDKin_1	790	796	PF00069	0.497
MOD_ProDKin_1	817	823	PF00069	0.611
MOD_ProDKin_1	881	887	PF00069	0.663
MOD_ProDKin_1	888	894	PF00069	0.611
MOD_ProDKin_1	896	902	PF00069	0.579
MOD_ProDKin_1	930	936	PF00069	0.712
MOD_ProDKin_1	952	958	PF00069	0.585
MOD_ProDKin_1	966	972	PF00069	0.624
MOD_ProDKin_1	975	981	PF00069	0.621
MOD_SUMO_for_1	149	152	PF00179	0.397
MOD_SUMO_rev_2	49	59	PF00179	0.426
TRG_DiLeu_BaEn_1	186	191	PF01217	0.385
TRG_DiLeu_BaEn_1	243	248	PF01217	0.473
TRG_ENDOCYTIC_2	32	35	PF00928	0.473
TRG_ENDOCYTIC_2	368	371	PF00928	0.395
TRG_ENDOCYTIC_2	442	445	PF00928	0.355
TRG_ENDOCYTIC_2	452	455	PF00928	0.417
TRG_ENDOCYTIC_2	497	500	PF00928	0.467
TRG_ENDOCYTIC_2	522	525	PF00928	0.588
TRG_ER_diArg_1	136	139	PF00400	0.473
TRG_ER_diArg_1	159	162	PF00400	0.445
TRG_ER_diArg_1	279	281	PF00400	0.518
TRG_ER_diArg_1	422	424	PF00400	0.426
TRG_ER_diArg_1	425	428	PF00400	0.374
TRG_ER_diArg_1	43	46	PF00400	0.451
TRG_ER_diArg_1	511	514	PF00400	0.480
TRG_ER_diArg_1	593	596	PF00400	0.586
TRG_ER_diArg_1	600	603	PF00400	0.571
TRG_ER_diArg_1	633	635	PF00400	0.524
TRG_NLS_MonoExtN_4	560	566	PF00514	0.666

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCG6	Leptomonas seymouri	49%	94%
A0A3Q8ICM3	Leishmania donovani	87%	100%
A4HD00	Leishmania braziliensis	72%	100%
A4I0I5	Leishmania infantum	87%	100%
Q4QB25	Leishmania major	88%	100%