Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AWE5_LEIMU

TriTrypDb:

LmxM.23.1263

Length:

269

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AWE5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AWE5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	178	180	PF00675	0.637
CLV_NRD_NRD_1	188	190	PF00675	0.591
CLV_NRD_NRD_1	239	241	PF00675	0.532
CLV_NRD_NRD_1	252	254	PF00675	0.478
CLV_NRD_NRD_1	48	50	PF00675	0.766
CLV_NRD_NRD_1	94	96	PF00675	0.606
CLV_PCSK_KEX2_1	178	180	PF00082	0.647
CLV_PCSK_KEX2_1	190	192	PF00082	0.590
CLV_PCSK_KEX2_1	239	241	PF00082	0.532
CLV_PCSK_KEX2_1	252	254	PF00082	0.478
CLV_PCSK_KEX2_1	93	95	PF00082	0.622
CLV_PCSK_PC1ET2_1	190	192	PF00082	0.657
CLV_PCSK_PC1ET2_1	93	95	PF00082	0.661
CLV_PCSK_SKI1_1	158	162	PF00082	0.577
CLV_PCSK_SKI1_1	178	182	PF00082	0.727
CLV_PCSK_SKI1_1	191	195	PF00082	0.570
CLV_PCSK_SKI1_1	50	54	PF00082	0.770
CLV_PCSK_SKI1_1	97	101	PF00082	0.724
DEG_SPOP_SBC_1	192	196	PF00917	0.725
DOC_CYCLIN_RxL_1	152	164	PF00134	0.681
DOC_CYCLIN_RxL_1	93	105	PF00134	0.615
DOC_MAPK_gen_1	93	101	PF00069	0.585
DOC_USP7_MATH_1	148	152	PF00917	0.643
DOC_USP7_MATH_1	23	27	PF00917	0.605
DOC_USP7_MATH_1	29	33	PF00917	0.672
DOC_USP7_MATH_1	42	46	PF00917	0.713
DOC_USP7_MATH_1	56	60	PF00917	0.587
DOC_USP7_MATH_1	65	69	PF00917	0.742
DOC_USP7_MATH_1	75	79	PF00917	0.510
DOC_USP7_UBL2_3	93	97	PF12436	0.550
DOC_WW_Pin1_4	76	81	PF00397	0.586
LIG_14-3-3_CanoR_1	146	153	PF00244	0.447
LIG_14-3-3_CanoR_1	158	163	PF00244	0.576
LIG_14-3-3_CanoR_1	178	184	PF00244	0.611
LIG_14-3-3_CanoR_1	49	55	PF00244	0.745
LIG_14-3-3_CanoR_1	94	100	PF00244	0.624
LIG_BIR_II_1	1	5	PF00653	0.537
LIG_BRCT_BRCA1_1	103	107	PF00533	0.720
LIG_FHA_1	140	146	PF00498	0.728
LIG_FHA_1	96	102	PF00498	0.573
LIG_FHA_2	119	125	PF00498	0.650
LIG_FHA_2	159	165	PF00498	0.564
LIG_FHA_2	224	230	PF00498	0.561
LIG_FHA_2	35	41	PF00498	0.601
LIG_FHA_2	85	91	PF00498	0.664
LIG_Pex14_2	107	111	PF04695	0.637
LIG_PTAP_UEV_1	212	217	PF05743	0.522
LIG_SH2_STAP1	168	172	PF00017	0.675
LIG_SH2_STAP1	241	245	PF00017	0.649
LIG_SH3_2	213	218	PF14604	0.748
LIG_SH3_2	80	85	PF14604	0.753
LIG_SH3_3	210	216	PF00018	0.749
LIG_SH3_3	77	83	PF00018	0.756
LIG_SUMO_SIM_par_1	158	164	PF11976	0.671
MOD_CK1_1	13	19	PF00069	0.759
MOD_CK1_1	151	157	PF00069	0.745
MOD_CK1_1	208	214	PF00069	0.693
MOD_CK1_1	22	28	PF00069	0.681
MOD_CK1_1	261	267	PF00069	0.683
MOD_CK2_1	118	124	PF00069	0.651
MOD_CK2_1	158	164	PF00069	0.570
MOD_CK2_1	223	229	PF00069	0.638
MOD_CK2_1	34	40	PF00069	0.696
MOD_CK2_1	84	90	PF00069	0.675
MOD_Cter_Amidation	47	50	PF01082	0.523
MOD_GlcNHglycan	148	151	PF01048	0.581
MOD_GlcNHglycan	197	200	PF01048	0.691
MOD_GlcNHglycan	21	24	PF01048	0.689
MOD_GlcNHglycan	210	213	PF01048	0.606
MOD_GlcNHglycan	42	45	PF01048	0.798
MOD_GlcNHglycan	46	49	PF01048	0.723
MOD_GlcNHglycan	58	61	PF01048	0.576
MOD_GlcNHglycan	67	70	PF01048	0.566
MOD_GSK3_1	18	25	PF00069	0.647
MOD_GSK3_1	191	198	PF00069	0.687
MOD_GSK3_1	40	47	PF00069	0.696
MOD_GSK3_1	65	72	PF00069	0.784
MOD_GSK3_1	84	91	PF00069	0.606
MOD_GSK3_1	9	16	PF00069	0.760
MOD_N-GLC_1	69	74	PF02516	0.529
MOD_NEK2_1	138	143	PF00069	0.672
MOD_PIKK_1	263	269	PF00454	0.672
MOD_PKA_2	14	20	PF00069	0.528
MOD_PKA_2	65	71	PF00069	0.711
MOD_PKB_1	144	152	PF00069	0.446
MOD_PKB_1	189	197	PF00069	0.742
MOD_PKB_1	258	266	PF00069	0.445
MOD_Plk_4	118	124	PF00069	0.622
MOD_Plk_4	158	164	PF00069	0.382
MOD_Plk_4	95	101	PF00069	0.583
MOD_ProDKin_1	76	82	PF00069	0.584
TRG_DiLeu_BaLyEn_6	155	160	PF01217	0.658
TRG_ER_diArg_1	177	179	PF00400	0.716
TRG_ER_diArg_1	238	240	PF00400	0.522
TRG_NLS_Bipartite_1	178	193	PF00514	0.701

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4W9	Leptomonas seymouri	49%	100%
A0A3S7WXU2	Leishmania donovani	84%	100%
A4HCZ8	Leishmania braziliensis	67%	100%
A4I0I3	Leishmania infantum	84%	100%
Q4QB27	Leishmania major	83%	100%