LeishMANIAdb
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Hydrophilic acylated surface protein a

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hydrophilic acylated surface protein a
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9AWB4_LEIMU
TriTrypDb:
LmxM.23.1020
Length:
117

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. no yes: 6
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AWB4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AWB4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 30 34 PF00656 0.803
CLV_C14_Caspase3-7 75 79 PF00656 0.667
DOC_WW_Pin1_4 37 42 PF00397 0.538
LIG_BIR_III_2 9 13 PF00653 0.759
LIG_TRAF2_2 41 46 PF00917 0.542
LIG_WRC_WIRS_1 1 6 PF05994 0.768
MOD_CK2_1 111 117 PF00069 0.567
MOD_NMyristoyl 1 7 PF02799 0.768
MOD_PIKK_1 111 117 PF00454 0.567
MOD_Plk_1 27 33 PF00069 0.804
MOD_ProDKin_1 37 43 PF00069 0.536
MOD_SUMO_for_1 100 103 PF00179 0.809
MOD_SUMO_rev_2 33 41 PF00179 0.634
MOD_SUMO_rev_2 75 84 PF00179 0.630

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8ICK5 Leishmania donovani 64% 100%
A4I0F1 Leishmania infantum 74% 89%
Q4QB61 Leishmania major 69% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS