Cytochrome c oxidase subunit 10

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cytochrome c oxidase subunit 10, putative

Species:

Leishmania mexicana

UniProt:

E9AW41_LEIMU

TriTrypDb:

LmxM.23.0370

Length:

118

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AW41

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AW41

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	4
GO:0016491	oxidoreductase activity	2	4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	35	39	PF00656	0.448
CLV_NRD_NRD_1	2	4	PF00675	0.480
CLV_NRD_NRD_1	50	52	PF00675	0.363
CLV_NRD_NRD_1	78	80	PF00675	0.383
CLV_NRD_NRD_1	86	88	PF00675	0.379
CLV_PCSK_KEX2_1	2	4	PF00082	0.480
CLV_PCSK_KEX2_1	86	88	PF00082	0.374
CLV_PCSK_SKI1_1	100	104	PF00082	0.375
CLV_PCSK_SKI1_1	2	6	PF00082	0.609
CLV_PCSK_SKI1_1	87	91	PF00082	0.364
DEG_Nend_UBRbox_1	1	4	PF02207	0.597
DOC_MAPK_FxFP_2	23	26	PF00069	0.426
DOC_PP1_RVXF_1	60	67	PF00149	0.386
DOC_PP1_RVXF_1	85	92	PF00149	0.407
DOC_PP4_FxxP_1	23	26	PF00568	0.426
DOC_WW_Pin1_4	25	30	PF00397	0.512
LIG_14-3-3_CanoR_1	100	105	PF00244	0.404
LIG_14-3-3_CanoR_1	2	11	PF00244	0.608
LIG_deltaCOP1_diTrp_1	88	98	PF00928	0.513
LIG_FHA_1	101	107	PF00498	0.351
LIG_FHA_1	3	9	PF00498	0.607
LIG_HCF-1_HBM_1	111	114	PF13415	0.404
LIG_LIR_Gen_1	63	73	PF02991	0.404
LIG_LIR_Nem_3	63	69	PF02991	0.419
LIG_LIR_Nem_3	97	102	PF02991	0.366
LIG_REV1ctd_RIR_1	96	104	PF16727	0.370
LIG_SH2_SRC	36	39	PF00017	0.461
LIG_SH2_STAT5	36	39	PF00017	0.432
LIG_SH3_3	23	29	PF00018	0.499
LIG_SUMO_SIM_par_1	30	35	PF11976	0.438
LIG_TRAF2_1	82	85	PF00917	0.473
MOD_GSK3_1	100	107	PF00069	0.355
MOD_NEK2_1	104	109	PF00069	0.393
MOD_PKA_1	2	8	PF00069	0.607
MOD_PKA_2	2	8	PF00069	0.607
MOD_ProDKin_1	25	31	PF00069	0.505
TRG_ER_diArg_1	1	3	PF00400	0.488

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKB5	Leptomonas seymouri	84%	99%
A0A0S4JCT0	Bodo saltans	71%	100%
A0A1X0NX91	Trypanosomatidae	73%	100%
A0A3S7WXI5	Leishmania donovani	92%	100%
A4HCQ2	Leishmania braziliensis	85%	100%
A4I077	Leishmania infantum	92%	100%
D0A9J4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	71%	100%
D0A9J6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	72%	100%
Q4QBD7	Leishmania major	92%	100%