Pteridine reductase 1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

pteridine reductase 1

Species:

Leishmania mexicana

UniProt:

E9AW30_LEIMU

TriTrypDb:

LmxM.23.0270

Length:

288

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 4
Forrest at al. (procyclic)	no	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005829	cytosol	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9AW30

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AW30

PDB structure(s): 1e7w_A , 1e7w_B , 1e92_A , 1e92_B , 1e92_C , 1e92_D , 1w0c_A , 1w0c_B , 1w0c_C , 1w0c_D , 1w0c_E , 1w0c_F , 1w0c_G , 1w0c_H , 2bf7_A , 2bf7_B , 2bf7_C , 2bf7_D , 2bfa_A , 2bfa_B , 2bfa_C , 2bfa_D , 2bfm_A , 2bfm_B , 2bfm_C , 2bfm_D , 2bfo_A , 2bfo_B , 2bfo_C , 2bfo_D , 2bfp_A , 2bfp_B , 2bfp_C , 2bfp_D , 2qhx_A , 2qhx_B , 2qhx_C , 2qhx_D , 3h4v_A , 3h4v_B , 3h4v_C , 3h4v_D , 3h4v_E , 3h4v_F , 3h4v_G , 3h4v_H , 5l42_A , 5l42_B , 5l42_C , 5l42_D , 5l4n_A , 5l4n_B , 5l4n_C , 5l4n_D , 6rxc_A , 6rxc_B , 6rxc_C , 6rxc_D , 7pxx_A , 7pxx_B , 7pxx_C , 7pxx_D

Function

Biological processes
Term	Name	Level	Count
GO:0006066	alcohol metabolic process	3	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006729	tetrahydrobiopterin biosynthetic process	6	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	3
GO:0009058	biosynthetic process	2	1
GO:0009987	cellular process	1	1
GO:0010033	response to organic substance	3	1
GO:0010243	response to organonitrogen compound	4	1
GO:0014070	response to organic cyclic compound	4	1
GO:0018130	heterocycle biosynthetic process	4	1
GO:0019438	aromatic compound biosynthetic process	4	1
GO:0019751	polyol metabolic process	4	1
GO:0031427	response to methotrexate	4	1
GO:0034311	diol metabolic process	5	1
GO:0034312	diol biosynthetic process	6	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0042221	response to chemical	2	1
GO:0042558	pteridine-containing compound metabolic process	4	1
GO:0042559	pteridine-containing compound biosynthetic process	5	1
GO:0044237	cellular metabolic process	2	1
GO:0044249	cellular biosynthetic process	3	1
GO:0044271	cellular nitrogen compound biosynthetic process	4	1
GO:0044281	small molecule metabolic process	2	1
GO:0044283	small molecule biosynthetic process	3	1
GO:0046146	tetrahydrobiopterin metabolic process	5	1
GO:0046165	alcohol biosynthetic process	4	1
GO:0046173	polyol biosynthetic process	5	1
GO:0046483	heterocycle metabolic process	3	1
GO:0050896	response to stimulus	1	1
GO:0071704	organic substance metabolic process	2	1
GO:1901360	organic cyclic compound metabolic process	3	1
GO:1901362	organic cyclic compound biosynthetic process	4	1
GO:1901564	organonitrogen compound metabolic process	3	1
GO:1901566	organonitrogen compound biosynthetic process	4	1
GO:1901576	organic substance biosynthetic process	3	1
GO:1901615	organic hydroxy compound metabolic process	3	1
GO:1901617	organic hydroxy compound biosynthetic process	4	1
GO:1901698	response to nitrogen compound	3	1
GO:1901700	response to oxygen-containing compound	3	1
GO:0032259	methylation	2	2

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	8
GO:0016491	oxidoreductase activity	2	8
GO:0004155	6,7-dihydropteridine reductase activity	5	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	3	4
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	4	4
GO:0047040	pteridine reductase activity	5	4
GO:0004146	dihydrofolate reductase activity	5	2
GO:0004799	thymidylate synthase activity	6	2
GO:0008168	methyltransferase activity	4	2
GO:0016740	transferase activity	2	2
GO:0016741	transferase activity, transferring one-carbon groups	3	2
GO:0042083	5,10-methylenetetrahydrofolate-dependent methyltransferase activity	5	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	40	44	PF00656	0.225
CLV_C14_Caspase3-7	91	95	PF00656	0.238
CLV_NRD_NRD_1	119	121	PF00675	0.324
CLV_NRD_NRD_1	54	56	PF00675	0.402
CLV_PCSK_KEX2_1	16	18	PF00082	0.394
CLV_PCSK_KEX2_1	54	56	PF00082	0.402
CLV_PCSK_KEX2_1	87	89	PF00082	0.303
CLV_PCSK_PC1ET2_1	16	18	PF00082	0.394
CLV_PCSK_PC1ET2_1	87	89	PF00082	0.303
CLV_PCSK_SKI1_1	133	137	PF00082	0.303
CLV_PCSK_SKI1_1	198	202	PF00082	0.335
CLV_PCSK_SKI1_1	270	274	PF00082	0.406
DOC_CKS1_1	114	119	PF01111	0.335
DOC_MAPK_gen_1	54	62	PF00069	0.394
DOC_USP7_MATH_1	224	228	PF00917	0.225
DOC_USP7_MATH_1	255	259	PF00917	0.391
DOC_USP7_MATH_1	70	74	PF00917	0.319
DOC_WW_Pin1_4	113	118	PF00397	0.335
LIG_14-3-3_CanoR_1	54	62	PF00244	0.502
LIG_EH1_1	173	181	PF00400	0.394
LIG_FHA_1	114	120	PF00498	0.335
LIG_FHA_1	138	144	PF00498	0.462
LIG_FHA_1	3	9	PF00498	0.512
LIG_LIR_Apic_2	111	117	PF02991	0.335
LIG_LIR_Gen_1	172	182	PF02991	0.417
LIG_LIR_Nem_3	172	177	PF02991	0.417
LIG_PCNA_yPIPBox_3	170	180	PF02747	0.367
LIG_PDZ_Class_1	283	288	PF00595	0.510
LIG_SH2_CRK	174	178	PF00017	0.394
LIG_SH2_NCK_1	174	178	PF00017	0.420
LIG_SH2_STAP1	31	35	PF00017	0.420
LIG_SH2_STAT5	152	155	PF00017	0.315
LIG_SH2_STAT5	191	194	PF00017	0.379
LIG_SH2_STAT5	241	244	PF00017	0.225
LIG_SH2_STAT5	271	274	PF00017	0.335
LIG_SH2_STAT5	97	100	PF00017	0.368
LIG_SH3_3	1	7	PF00018	0.557
LIG_SUMO_SIM_par_1	5	12	PF11976	0.423
LIG_TYR_ITSM	170	177	PF00017	0.368
MOD_CDK_SPxxK_3	113	120	PF00069	0.371
MOD_CK1_1	58	64	PF00069	0.378
MOD_CK2_1	250	256	PF00069	0.503
MOD_GlcNHglycan	127	130	PF01048	0.225
MOD_GlcNHglycan	19	22	PF01048	0.360
MOD_GlcNHglycan	206	209	PF01048	0.364
MOD_GlcNHglycan	251	255	PF01048	0.409
MOD_GlcNHglycan	39	42	PF01048	0.512
MOD_GlcNHglycan	57	60	PF01048	0.240
MOD_GlcNHglycan	78	82	PF01048	0.387
MOD_GSK3_1	109	116	PF00069	0.368
MOD_GSK3_1	133	140	PF00069	0.225
MOD_GSK3_1	43	50	PF00069	0.422
MOD_GSK3_1	70	77	PF00069	0.375
MOD_N-GLC_1	108	113	PF02516	0.366
MOD_N-GLC_1	172	177	PF02516	0.394
MOD_NEK2_1	143	148	PF00069	0.394
MOD_NEK2_1	189	194	PF00069	0.419
MOD_NEK2_1	204	209	PF00069	0.310
MOD_NEK2_1	263	268	PF00069	0.420
MOD_NEK2_1	47	52	PF00069	0.468
MOD_PKA_2	169	175	PF00069	0.368
MOD_PKA_2	249	255	PF00069	0.420
MOD_Plk_1	108	114	PF00069	0.335
MOD_Plk_1	172	178	PF00069	0.394
MOD_Plk_4	109	115	PF00069	0.368
MOD_Plk_4	172	178	PF00069	0.394
MOD_Plk_4	189	195	PF00069	0.405
MOD_Plk_4	224	230	PF00069	0.394
MOD_Plk_4	81	87	PF00069	0.371
MOD_ProDKin_1	113	119	PF00069	0.335
TRG_DiLeu_BaLyEn_6	114	119	PF01217	0.335
TRG_DiLeu_BaLyEn_6	184	189	PF01217	0.394
TRG_ENDOCYTIC_2	152	155	PF00928	0.371
TRG_ENDOCYTIC_2	174	177	PF00928	0.394
TRG_ER_diArg_1	54	56	PF00400	0.492

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0B4FP77	Metarhizium brunneum (strain ARSEF 3297)	23%	100%
A0A0B4GT47	Metarhizium anisopliae (strain ARSEF 549)	24%	100%
A0A0B4GU97	Metarhizium guizhouense (strain ARSEF 977)	24%	100%
A0A0B4HVU2	Metarhizium majus (strain ARSEF 297)	24%	100%
A0A0N1I5Q6	Leptomonas seymouri	65%	100%
A0A0N1PCK0	Leptomonas seymouri	28%	100%
A0A0S4JMY5	Bodo saltans	27%	100%
A0A0S4JTE1	Bodo saltans	28%	100%
A0A165U5V5	Euphorbia lathyris	26%	100%
A0A1A9TAK5	Narcissus pseudonarcissus	27%	100%
A0A1C9II22	Narcissus aff. pseudonarcissus MK-2014	27%	100%
A0A1L5BU05	Sphingobium indicum (strain DSM 16412 / CCM 7286 / MTCC 6364 / B90A)	24%	100%
A0A1X0NG18	Trypanosomatidae	47%	100%
A0A2I1C3T5	Aspergillus novofumigatus (strain IBT 16806)	23%	100%
A0A3Q8IF11	Leishmania donovani	25%	100%
A0A3S7WXI3	Leishmania donovani	91%	100%
A0A411PQN6	Paecilomyces divaricatus	25%	100%
A0A4P8DJW8	Cryptosporiopsis sp. (strain 8999)	22%	100%
A0A8F5SIS3	Salvia officinalis	26%	100%
A0A8F5XX49	Salvia officinalis	28%	100%
A4HCP1	Leishmania braziliensis	75%	100%
A4I067	Leishmania infantum	91%	100%
A4I111	Leishmania infantum	25%	100%
A5W4G5	Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)	26%	100%
A6T8N3	Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)	24%	100%
A7B3K3	Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9)	25%	100%
A9CES4	Agrobacterium fabrum (strain C58 / ATCC 33970)	26%	100%
B0ZT44	Elsinoe fawcettii	24%	100%
C1C4R8	Lithobates catesbeianus	25%	100%
C8WGQ3	Eggerthella lenta (strain ATCC 25559 / DSM 2243 / CCUG 17323 / JCM 9979 / KCTC 3265 / NCTC 11813 / VPI 0255 / 1899 B)	26%	100%
D4Z260	Sphingobium japonicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S)	24%	100%
E9EHG1	Metarhizium acridum (strain CQMa 102)	24%	100%
E9ET40	Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075)	24%	100%
F1SWA0	Zingiber zerumbet	25%	100%
G0RNA2	Hypocrea jecorina (strain QM6a)	27%	95%
G3YG17	Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a / NRRL 328 / USDA 3528.7)	26%	97%
G4N290	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	33%	100%
G5EGA6	Caenorhabditis elegans	28%	100%
G9FRD7	Clostridium sardiniense	25%	100%
H9BFQ2	Erythroxylum coca	28%	100%
M1W270	Claviceps purpurea (strain 20.1)	22%	100%
O00058	Uromyces fabae	26%	100%
O02691	Bos taurus	26%	100%
O07399	Mycobacterium avium	26%	100%
O07575	Bacillus subtilis (strain 168)	23%	100%
O31642	Bacillus subtilis (strain 168)	24%	100%
O31767	Bacillus subtilis (strain 168)	29%	100%
O34308	Bacillus subtilis (strain 168)	23%	100%
O54438	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	32%	100%
O67610	Aquifex aeolicus (strain VF5)	30%	100%
P06234	Rhizobium meliloti (strain 1021)	26%	100%
P07772	Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)	26%	100%
P07999	Priestia megaterium	25%	100%
P08074	Mus musculus	31%	100%
P0A0H9	Staphylococcus aureus (strain Mu50 / ATCC 700699)	30%	100%
P0A0I0	Staphylococcus aureus (strain MW2)	30%	100%
P0A2C9	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	27%	100%
P0A2D0	Salmonella typhi	27%	100%
P0A2D1	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	26%	100%
P0A2D2	Salmonella typhi	26%	100%
P0A9P9	Escherichia coli (strain K12)	27%	100%
P0A9Q0	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	27%	100%
P0AEK2	Escherichia coli (strain K12)	28%	100%
P0AEK3	Shigella flexneri	28%	100%
P0AET8	Escherichia coli (strain K12)	25%	100%
P0AET9	Escherichia coli O157:H7	25%	100%
P0C622	Pseudomonas putida	26%	100%
P0CG22	Homo sapiens	25%	100%
P0CU75	Passalora fulva	22%	100%
P0DOV5	Pseudomonas putida	25%	100%
P10528	Priestia megaterium	27%	100%
P12310	Bacillus subtilis (strain 168)	24%	100%
P14697	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	26%	100%
P16542	Streptomyces violaceoruber	28%	100%
P16543	Streptomyces violaceoruber	31%	100%
P17611	Azospirillum brasilense	27%	100%
P23102	Pseudomonas putida	26%	100%
P28643	Cuphea lanceolata	25%	90%
P33207	Arabidopsis thaliana	30%	90%
P33368	Escherichia coli (strain K12)	29%	100%
P37079	Klebsiella pneumoniae	31%	100%
P37440	Escherichia coli (strain K12)	26%	100%
P37769	Escherichia coli (strain K12)	26%	100%
P39482	Priestia megaterium	26%	100%
P39483	Priestia megaterium	27%	100%
P39484	Priestia megaterium	27%	100%
P39485	Priestia megaterium	27%	100%
P39640	Bacillus subtilis (strain 168)	27%	100%
P40288	Priestia megaterium	26%	100%
P40397	Bacillus subtilis (strain 168)	27%	100%
P41177	Streptomyces virginiae	28%	100%
P42317	Bacillus subtilis (strain 168)	28%	100%
P42556	Leishmania tarentolae	83%	100%
P43713	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	27%	100%
P50162	Datura stramonium	27%	100%
P50163	Datura stramonium	27%	100%
P50164	Hyoscyamus niger	27%	100%
P50165	Datura stramonium	27%	100%
P50167	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	25%	100%
P50199	Gluconobacter oxydans (strain 621H)	27%	100%
P50200	Paeniclostridium sordellii	27%	100%
P50842	Bacillus subtilis (strain 168)	26%	100%
P50941	Rickettsia prowazekii (strain Madrid E)	27%	100%
P51831	Bacillus subtilis (strain 168)	26%	100%
P52037	Escherichia coli (strain K12)	27%	100%
P55336	Vibrio harveyi	28%	100%
P55575	Sinorhizobium fredii (strain NBRC 101917 / NGR234)	26%	100%
P57432	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	27%	100%
P66775	Staphylococcus aureus (strain Mu50 / ATCC 700699)	26%	100%
P66776	Staphylococcus aureus (strain MW2)	26%	100%
P66782	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	27%	100%
P71079	Bacillus subtilis (strain 168)	30%	100%
P71534	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	28%	100%
P72332	Rhizobium sp. (strain N33)	28%	100%
P73574	Synechocystis sp. (strain PCC 6803 / Kazusa)	32%	100%
P80869	Bacillus subtilis (strain 168)	27%	100%
P80873	Bacillus subtilis (strain 168)	22%	100%
P87218	Candida albicans (strain SC5314 / ATCC MYA-2876)	25%	100%
P94681	Comamonas testosteroni	30%	100%
P99093	Staphylococcus aureus (strain N315)	30%	100%
P99120	Staphylococcus aureus (strain N315)	26%	100%
P9WGQ4	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	28%	100%
P9WGQ5	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	28%	100%
P9WGR8	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	27%	100%
P9WGR9	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	27%	100%
Q01782	Leishmania major	87%	100%
Q04520	Raoultella terrigena	26%	100%
Q05528	Dickeya dadantii (strain 3937)	25%	100%
Q08632	Picea abies	28%	100%
Q10216	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	29%	100%
Q1JP75	Bos taurus	31%	100%
Q1MLL4	Rhizobium leguminosarum bv. viciae (strain 3841)	28%	100%
Q29529	Sus scrofa	29%	100%
Q2UEK6	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	29%	100%
Q3KPT7	Xenopus laevis	26%	100%
Q49117	Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1)	30%	100%
Q4A054	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	24%	100%
Q4QAC7	Leishmania major	24%	95%
Q53882	Streptomyces sp. (strain C5)	32%	100%
Q561X9	Danio rerio	26%	100%
Q56840	Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)	27%	100%
Q59787	Cereibacter sphaeroides	28%	100%
Q5BH34	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	25%	100%
Q5FPE5	Gluconobacter oxydans (strain 621H)	27%	100%
Q5HGK2	Staphylococcus aureus (strain COL)	30%	100%
Q5HJP2	Staphylococcus aureus (strain COL)	26%	100%
Q5HKG6	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	27%	100%
Q5HPW0	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	30%	100%
Q5KTS5	Daucus carota	26%	99%
Q5LA59	Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow)	26%	100%
Q5P5I4	Aromatoleum aromaticum (strain EbN1)	26%	100%
Q5RBV3	Pongo abelii	26%	99%
Q5RCF8	Pongo abelii	28%	100%
Q5RCH8	Pongo abelii	28%	95%
Q5TJF5	Canis lupus familiaris	28%	100%
Q68VY7	Rickettsia typhi (strain ATCC VR-144 / Wilmington)	27%	100%
Q6G9Y2	Staphylococcus aureus (strain MSSA476)	30%	100%
Q6GCZ8	Staphylococcus aureus (strain MSSA476)	26%	100%
Q6GHK4	Staphylococcus aureus (strain MRSA252)	30%	100%
Q6GKH9	Staphylococcus aureus (strain MRSA252)	26%	100%
Q6TMA3	Rhodococcus sp. (strain TK6)	27%	100%
Q6WVP7	Lentilactobacillus kefiri	26%	100%
Q75KH3	Oryza sativa subsp. japonica	30%	96%
Q7SHI4	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	32%	100%
Q7Z4W1	Homo sapiens	29%	100%
Q89AG9	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	26%	100%
Q8CPI3	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	30%	100%
Q8CQD2	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	29%	100%
Q8GAV9	Comamonas sp. (strain NCIMB 9872)	29%	100%
Q8JIS3	Gallus gallus	29%	100%
Q8K9J5	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	25%	100%
Q8RX32	Arabidopsis thaliana	28%	100%
Q8SPU8	Bos taurus	29%	100%
Q8VID1	Rattus norvegicus	29%	100%
Q8WNV7	Sus scrofa	29%	100%
Q8XBJ4	Escherichia coli O157:H7	26%	100%
Q91X52	Mus musculus	29%	100%
Q91XV4	Mesocricetus auratus	28%	100%
Q920N9	Cavia porcellus	29%	100%
Q920P0	Rattus norvegicus	29%	100%
Q92506	Homo sapiens	27%	100%
Q92RN6	Rhizobium meliloti (strain 1021)	25%	100%
Q937L4	Comamonas testosteroni	29%	100%
Q93X62	Brassica napus	28%	90%
Q93X67	Brassica napus	30%	88%
Q93X68	Brassica napus	27%	91%
Q949M2	Brassica napus	28%	100%
Q949M3	Brassica napus	28%	91%
Q99LB2	Mus musculus	29%	100%
Q9BTZ2	Homo sapiens	28%	100%
Q9BY49	Homo sapiens	27%	95%
Q9C826	Arabidopsis thaliana	27%	100%
Q9FZ42	Arabidopsis thaliana	25%	100%
Q9GKX2	Oryctolagus cuniculus	28%	100%
Q9JIF5	Cavia porcellus	30%	95%
Q9KQH7	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	28%	100%
Q9L9F8	Streptomyces niveus	28%	100%
Q9LBG2	Leifsonia aquatica	27%	100%
Q9LHT0	Arabidopsis thaliana	27%	100%
Q9MA93	Arabidopsis thaliana	27%	100%
Q9NUI1	Homo sapiens	26%	99%
Q9PKF7	Chlamydia muridarum (strain MoPn / Nigg)	27%	100%
Q9RA05	Rhodococcus erythropolis	26%	100%
Q9S9W2	Arabidopsis thaliana	25%	100%
Q9SQR4	Arabidopsis thaliana	24%	100%
Q9WYG0	Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)	26%	100%
Q9X248	Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)	30%	100%
Q9Z8P2	Chlamydia pneumoniae	24%	100%
Q9ZNN8	Corynebacterium glutamicum	28%	100%
Q9ZW03	Arabidopsis thaliana	28%	100%
Q9ZW12	Arabidopsis thaliana	26%	89%
Q9ZW13	Arabidopsis thaliana	26%	100%
Q9ZW14	Arabidopsis thaliana	28%	100%
Q9ZW19	Arabidopsis thaliana	25%	100%
Q9ZW20	Arabidopsis thaliana	26%	100%
T2KLZ8	Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1)	25%	100%