Foie-gras_1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AW19_LEIMU

TriTrypDb:

LmxM.23.0180

Length:

295

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AW19

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AW19

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	118	122	PF00656	0.746
CLV_C14_Caspase3-7	20	24	PF00656	0.502
CLV_NRD_NRD_1	115	117	PF00675	0.446
CLV_NRD_NRD_1	218	220	PF00675	0.335
CLV_NRD_NRD_1	250	252	PF00675	0.539
CLV_NRD_NRD_1	259	261	PF00675	0.427
CLV_NRD_NRD_1	79	81	PF00675	0.419
CLV_PCSK_KEX2_1	115	117	PF00082	0.446
CLV_PCSK_KEX2_1	250	252	PF00082	0.539
CLV_PCSK_KEX2_1	259	261	PF00082	0.427
CLV_PCSK_KEX2_1	79	81	PF00082	0.519
CLV_PCSK_SKI1_1	84	88	PF00082	0.348
DEG_APCC_DBOX_1	258	266	PF00400	0.492
DEG_APCC_DBOX_1	282	290	PF00400	0.336
DEG_Nend_UBRbox_4	1	3	PF02207	0.509
DEG_SPOP_SBC_1	109	113	PF00917	0.556
DOC_CDC14_PxL_1	3	11	PF14671	0.425
DOC_CYCLIN_yCln2_LP_2	126	132	PF00134	0.369
DOC_MAPK_gen_1	219	225	PF00069	0.361
DOC_PP2B_LxvP_1	126	129	PF13499	0.665
DOC_PP2B_LxvP_1	145	148	PF13499	0.353
DOC_USP7_MATH_1	109	113	PF00917	0.689
DOC_USP7_MATH_1	195	199	PF00917	0.419
DOC_USP7_MATH_1	94	98	PF00917	0.458
DOC_WW_Pin1_4	110	115	PF00397	0.664
DOC_WW_Pin1_4	51	56	PF00397	0.534
LIG_14-3-3_CanoR_1	115	123	PF00244	0.432
LIG_14-3-3_CanoR_1	12	21	PF00244	0.585
LIG_14-3-3_CanoR_1	163	173	PF00244	0.319
LIG_eIF4E_1	173	179	PF01652	0.356
LIG_FHA_1	38	44	PF00498	0.435
LIG_FHA_1	51	57	PF00498	0.497
LIG_FHA_1	6	12	PF00498	0.430
LIG_FHA_2	147	153	PF00498	0.538
LIG_FHA_2	253	259	PF00498	0.382
LIG_LIR_Gen_1	158	169	PF02991	0.521
LIG_LIR_Gen_1	240	249	PF02991	0.366
LIG_LIR_Gen_1	281	289	PF02991	0.493
LIG_LIR_Nem_3	127	133	PF02991	0.433
LIG_LIR_Nem_3	149	153	PF02991	0.502
LIG_LIR_Nem_3	158	164	PF02991	0.425
LIG_LIR_Nem_3	240	246	PF02991	0.432
LIG_LIR_Nem_3	281	287	PF02991	0.516
LIG_LIR_Nem_3	288	294	PF02991	0.498
LIG_MYND_1	272	276	PF01753	0.576
LIG_SH2_CRK	284	288	PF00017	0.454
LIG_SH2_STAP1	150	154	PF00017	0.501
LIG_SH2_STAP1	157	161	PF00017	0.484
LIG_SH2_STAP1	166	170	PF00017	0.483
LIG_SH2_STAP1	243	247	PF00017	0.376
LIG_SH2_STAT5	132	135	PF00017	0.348
LIG_SH2_STAT5	144	147	PF00017	0.319
LIG_SH2_STAT5	153	156	PF00017	0.384
LIG_SH2_STAT5	157	160	PF00017	0.389
LIG_SH2_STAT5	173	176	PF00017	0.229
LIG_TRFH_1	144	148	PF08558	0.324
LIG_TYR_ITIM	241	246	PF00017	0.362
LIG_UBA3_1	71	77	PF00899	0.387
MOD_CDC14_SPxK_1	113	116	PF00782	0.433
MOD_CDC14_SPxK_1	54	57	PF00782	0.373
MOD_CDK_SPK_2	110	115	PF00069	0.431
MOD_CDK_SPxK_1	110	116	PF00069	0.432
MOD_CDK_SPxK_1	51	57	PF00069	0.416
MOD_CK1_1	13	19	PF00069	0.461
MOD_CK2_1	252	258	PF00069	0.538
MOD_CK2_1	41	47	PF00069	0.637
MOD_GlcNHglycan	118	121	PF01048	0.606
MOD_GSK3_1	37	44	PF00069	0.433
MOD_NEK2_1	155	160	PF00069	0.447
MOD_NEK2_2	188	193	PF00069	0.384
MOD_PIKK_1	13	19	PF00454	0.461
MOD_PKA_1	115	121	PF00069	0.436
MOD_PKA_2	115	121	PF00069	0.442
MOD_Plk_1	155	161	PF00069	0.491
MOD_Plk_1	195	201	PF00069	0.496
MOD_Plk_4	285	291	PF00069	0.538
MOD_ProDKin_1	110	116	PF00069	0.664
MOD_ProDKin_1	51	57	PF00069	0.525
TRG_ENDOCYTIC_2	144	147	PF00928	0.323
TRG_ENDOCYTIC_2	166	169	PF00928	0.557
TRG_ENDOCYTIC_2	243	246	PF00928	0.371
TRG_ENDOCYTIC_2	284	287	PF00928	0.538
TRG_ER_diArg_1	114	116	PF00400	0.433
TRG_ER_diArg_1	60	63	PF00400	0.579
TRG_ER_diArg_1	78	80	PF00400	0.462
TRG_Pf-PMV_PEXEL_1	104	108	PF00026	0.441
TRG_Pf-PMV_PEXEL_1	12	17	PF00026	0.456

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAY1	Leptomonas seymouri	57%	100%
A0A3Q8ICJ3	Leishmania donovani	85%	100%
A0A422NVZ5	Trypanosoma rangeli	38%	100%
A4HCN2	Leishmania braziliensis	76%	100%
A4I056	Leishmania infantum	86%	100%
Q4QBF7	Leishmania major	85%	100%
V5AYT6	Trypanosoma cruzi	38%	100%
V5D0F5	Trypanosoma cruzi	38%	100%