Calpain-like cysteine peptidase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AVY3_LEIMU

TriTrypDb:

LmxM.22.1510

Length:

499

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AVY3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AVY3

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	366	370	PF00656	0.478
CLV_C14_Caspase3-7	419	423	PF00656	0.496
CLV_NRD_NRD_1	222	224	PF00675	0.797
CLV_NRD_NRD_1	4	6	PF00675	0.631
CLV_PCSK_KEX2_1	383	385	PF00082	0.646
CLV_PCSK_KEX2_1	424	426	PF00082	0.479
CLV_PCSK_PC1ET2_1	383	385	PF00082	0.646
CLV_PCSK_PC1ET2_1	424	426	PF00082	0.479
CLV_PCSK_SKI1_1	176	180	PF00082	0.768
CLV_PCSK_SKI1_1	240	244	PF00082	0.519

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PC61	Leptomonas seymouri	41%	91%
A0A3Q8IBJ7	Leishmania donovani	88%	100%
A4I010	Leishmania infantum	88%	100%
Q4QBJ6	Leishmania major	89%	100%

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