MORN repeat-containing protein 5

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AVV9_LEIMU

TriTrypDb:

LmxM.22.1270

Length:

547

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AVV9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AVV9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	367	371	PF00656	0.622
CLV_C14_Caspase3-7	451	455	PF00656	0.727
CLV_C14_Caspase3-7	490	494	PF00656	0.603
CLV_NRD_NRD_1	11	13	PF00675	0.520
CLV_NRD_NRD_1	151	153	PF00675	0.639
CLV_NRD_NRD_1	307	309	PF00675	0.671
CLV_NRD_NRD_1	322	324	PF00675	0.476
CLV_NRD_NRD_1	350	352	PF00675	0.758
CLV_NRD_NRD_1	442	444	PF00675	0.787
CLV_PCSK_KEX2_1	11	13	PF00082	0.520
CLV_PCSK_KEX2_1	151	153	PF00082	0.639
CLV_PCSK_KEX2_1	3	5	PF00082	0.503
CLV_PCSK_KEX2_1	309	311	PF00082	0.693
CLV_PCSK_KEX2_1	322	324	PF00082	0.494
CLV_PCSK_KEX2_1	442	444	PF00082	0.742
CLV_PCSK_PC1ET2_1	3	5	PF00082	0.503
CLV_PCSK_PC1ET2_1	309	311	PF00082	0.693
DEG_SPOP_SBC_1	93	97	PF00917	0.465
DOC_ANK_TNKS_1	218	225	PF00023	0.520
DOC_CKS1_1	101	106	PF01111	0.466
DOC_MAPK_gen_1	20	30	PF00069	0.535
DOC_PP1_RVXF_1	80	86	PF00149	0.470
DOC_PP2B_LxvP_1	210	213	PF13499	0.614
DOC_PP4_FxxP_1	184	187	PF00568	0.542
DOC_PP4_FxxP_1	233	236	PF00568	0.674
DOC_USP7_MATH_1	124	128	PF00917	0.534
DOC_USP7_MATH_1	229	233	PF00917	0.427
DOC_USP7_MATH_1	247	251	PF00917	0.537
DOC_USP7_MATH_1	365	369	PF00917	0.785
DOC_USP7_MATH_1	437	441	PF00917	0.778
DOC_USP7_MATH_1	93	97	PF00917	0.471
DOC_WW_Pin1_4	130	135	PF00397	0.564
DOC_WW_Pin1_4	40	45	PF00397	0.458
DOC_WW_Pin1_4	432	437	PF00397	0.754
DOC_WW_Pin1_4	64	69	PF00397	0.495
DOC_WW_Pin1_4	97	102	PF00397	0.468
LIG_14-3-3_CanoR_1	11	17	PF00244	0.520
LIG_14-3-3_CanoR_1	158	162	PF00244	0.527
LIG_14-3-3_CanoR_1	201	210	PF00244	0.546
LIG_14-3-3_CanoR_1	442	447	PF00244	0.552
LIG_14-3-3_CanoR_1	55	60	PF00244	0.458
LIG_14-3-3_CanoR_1	82	86	PF00244	0.482
LIG_BIR_III_4	493	497	PF00653	0.559
LIG_FHA_1	112	118	PF00498	0.487
LIG_FHA_1	202	208	PF00498	0.589
LIG_FHA_1	237	243	PF00498	0.699
LIG_FHA_1	476	482	PF00498	0.697
LIG_FHA_1	60	66	PF00498	0.489
LIG_FHA_2	365	371	PF00498	0.670
LIG_FHA_2	397	403	PF00498	0.653
LIG_FHA_2	488	494	PF00498	0.723
LIG_Integrin_RGD_1	216	218	PF01839	0.658
LIG_LIR_Apic_2	232	236	PF02991	0.440
LIG_LIR_Gen_1	256	261	PF02991	0.657
LIG_LIR_Gen_1	57	68	PF02991	0.481
LIG_LIR_Nem_3	24	30	PF02991	0.471
LIG_LIR_Nem_3	256	260	PF02991	0.665
LIG_LIR_Nem_3	57	63	PF02991	0.471
LIG_PCNA_yPIPBox_3	524	538	PF02747	0.694
LIG_Pex14_2	85	89	PF04695	0.462
LIG_REV1ctd_RIR_1	181	186	PF16727	0.590
LIG_SH2_CRK	159	163	PF00017	0.318
LIG_SH2_CRK	60	64	PF00017	0.483
LIG_SH2_NCK_1	60	64	PF00017	0.483
LIG_SH2_STAP1	60	64	PF00017	0.483
LIG_SH2_STAT3	142	145	PF00017	0.560
LIG_SH2_STAT3	286	289	PF00017	0.470
LIG_SH2_STAT5	142	145	PF00017	0.560
LIG_SH2_STAT5	159	162	PF00017	0.470
LIG_SH2_STAT5	167	170	PF00017	0.362
LIG_SH2_STAT5	286	289	PF00017	0.470
LIG_SH2_STAT5	316	319	PF00017	0.711
LIG_SH2_STAT5	328	331	PF00017	0.530
LIG_SH3_3	114	120	PF00018	0.509
LIG_SH3_3	331	337	PF00018	0.692
LIG_SH3_3	35	41	PF00018	0.525
LIG_SH3_3	359	365	PF00018	0.529
LIG_SH3_3	50	56	PF00018	0.456
LIG_SH3_3	510	516	PF00018	0.809
LIG_SH3_3	541	547	PF00018	0.653
LIG_SH3_3	65	71	PF00018	0.456
LIG_SH3_3	98	104	PF00018	0.481
LIG_SUMO_SIM_anti_2	113	119	PF11976	0.472
LIG_SUMO_SIM_par_1	456	466	PF11976	0.670
LIG_SUMO_SIM_par_1	529	535	PF11976	0.681
LIG_UBA3_1	347	352	PF00899	0.632
LIG_WRC_WIRS_1	230	235	PF05994	0.425
MOD_CDK_SPxK_1	102	108	PF00069	0.477
MOD_CK1_1	102	108	PF00069	0.522
MOD_CK1_1	125	131	PF00069	0.527
MOD_CK1_1	240	246	PF00069	0.767
MOD_CK1_1	296	302	PF00069	0.706
MOD_CK1_1	73	79	PF00069	0.484
MOD_CK2_1	130	136	PF00069	0.557
MOD_CK2_1	294	300	PF00069	0.609
MOD_CK2_1	357	363	PF00069	0.752
MOD_Cter_Amidation	1	4	PF01082	0.508
MOD_Cter_Amidation	149	152	PF01082	0.616
MOD_DYRK1A_RPxSP_1	40	44	PF00069	0.458
MOD_GlcNHglycan	198	201	PF01048	0.768
MOD_GlcNHglycan	220	223	PF01048	0.527
MOD_GlcNHglycan	263	266	PF01048	0.699
MOD_GlcNHglycan	296	299	PF01048	0.685
MOD_GlcNHglycan	300	305	PF01048	0.694
MOD_GlcNHglycan	367	370	PF01048	0.778
MOD_GlcNHglycan	465	468	PF01048	0.650
MOD_GlcNHglycan	77	80	PF01048	0.479
MOD_GSK3_1	236	243	PF00069	0.744
MOD_GSK3_1	296	303	PF00069	0.595
MOD_GSK3_1	365	372	PF00069	0.734
MOD_GSK3_1	438	445	PF00069	0.766
MOD_GSK3_1	55	62	PF00069	0.463
MOD_GSK3_1	66	73	PF00069	0.462
MOD_GSK3_1	93	100	PF00069	0.477
MOD_N-GLC_1	125	130	PF02516	0.541
MOD_NEK2_1	111	116	PF00069	0.496
MOD_NEK2_1	260	265	PF00069	0.672
MOD_NEK2_1	463	468	PF00069	0.717
MOD_NEK2_1	59	64	PF00069	0.479
MOD_NEK2_1	94	99	PF00069	0.519
MOD_OFUCOSY	92	98	PF10250	0.467
MOD_PIKK_1	10	16	PF00454	0.482
MOD_PKA_1	309	315	PF00069	0.680
MOD_PKA_1	357	363	PF00069	0.692
MOD_PKA_1	442	448	PF00069	0.830
MOD_PKA_2	10	16	PF00069	0.520
MOD_PKA_2	157	163	PF00069	0.527
MOD_PKA_2	19	25	PF00069	0.524
MOD_PKA_2	218	224	PF00069	0.654
MOD_PKA_2	309	315	PF00069	0.680
MOD_PKA_2	404	410	PF00069	0.540
MOD_PKA_2	442	448	PF00069	0.782
MOD_PKA_2	54	60	PF00069	0.459
MOD_PKA_2	73	79	PF00069	0.454
MOD_PKA_2	81	87	PF00069	0.469
MOD_Plk_1	300	306	PF00069	0.592
MOD_Plk_1	358	364	PF00069	0.526
MOD_Plk_4	113	119	PF00069	0.535
MOD_Plk_4	229	235	PF00069	0.426
MOD_Plk_4	309	315	PF00069	0.616
MOD_Plk_4	42	48	PF00069	0.464
MOD_Plk_4	442	448	PF00069	0.715
MOD_Plk_4	55	61	PF00069	0.439
MOD_Plk_4	81	87	PF00069	0.466
MOD_ProDKin_1	130	136	PF00069	0.560
MOD_ProDKin_1	40	46	PF00069	0.461
MOD_ProDKin_1	432	438	PF00069	0.756
MOD_ProDKin_1	64	70	PF00069	0.488
MOD_ProDKin_1	97	103	PF00069	0.468
MOD_SUMO_for_1	356	359	PF00179	0.664
TRG_DiLeu_BaLyEn_6	343	348	PF01217	0.692
TRG_ENDOCYTIC_2	272	275	PF00928	0.470
TRG_ENDOCYTIC_2	60	63	PF00928	0.480
TRG_ER_diArg_1	151	153	PF00400	0.604
TRG_ER_diArg_1	322	324	PF00400	0.669
TRG_Pf-PMV_PEXEL_1	322	326	PF00026	0.674
TRG_Pf-PMV_PEXEL_1	529	534	PF00026	0.687
TRG_Pf-PMV_PEXEL_1	538	542	PF00026	0.569

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ICB1	Leishmania donovani	90%	100%
A4HCG8	Leishmania braziliensis	75%	99%
E9AGZ7	Leishmania infantum	89%	100%
Q4QBM0	Leishmania major	88%	100%