Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AVT4_LEIMU

TriTrypDb:

LmxM.22.1020

Length:

492

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AVT4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AVT4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	184	188	PF00656	0.684
CLV_C14_Caspase3-7	372	376	PF00656	0.624
CLV_C14_Caspase3-7	381	385	PF00656	0.554
CLV_C14_Caspase3-7	408	412	PF00656	0.435
CLV_C14_Caspase3-7	74	78	PF00656	0.587
CLV_NRD_NRD_1	143	145	PF00675	0.596
CLV_NRD_NRD_1	30	32	PF00675	0.537
CLV_NRD_NRD_1	447	449	PF00675	0.548
CLV_NRD_NRD_1	459	461	PF00675	0.477
CLV_PCSK_KEX2_1	143	145	PF00082	0.596
CLV_PCSK_KEX2_1	30	32	PF00082	0.595
CLV_PCSK_KEX2_1	459	461	PF00082	0.546
CLV_PCSK_SKI1_1	116	120	PF00082	0.724
CLV_PCSK_SKI1_1	237	241	PF00082	0.610
CLV_PCSK_SKI1_1	488	492	PF00082	0.609
DEG_SPOP_SBC_1	345	349	PF00917	0.655
DEG_SPOP_SBC_1	377	381	PF00917	0.814
DEG_SPOP_SBC_1	72	76	PF00917	0.586
DOC_CKS1_1	120	125	PF01111	0.586
DOC_CKS1_1	296	301	PF01111	0.553
DOC_CKS1_1	313	318	PF01111	0.541
DOC_CYCLIN_yClb3_PxF_3	177	185	PF00134	0.692
DOC_PP1_RVXF_1	235	241	PF00149	0.558
DOC_PP1_RVXF_1	478	485	PF00149	0.491
DOC_PP2B_LxvP_1	126	129	PF13499	0.684
DOC_PP2B_LxvP_1	158	161	PF13499	0.746
DOC_PP4_FxxP_1	240	243	PF00568	0.549
DOC_USP7_MATH_1	149	153	PF00917	0.655
DOC_USP7_MATH_1	163	167	PF00917	0.794
DOC_USP7_MATH_1	283	287	PF00917	0.568
DOC_USP7_MATH_1	345	349	PF00917	0.704
DOC_USP7_MATH_1	366	370	PF00917	0.677
DOC_USP7_MATH_1	377	381	PF00917	0.676
DOC_USP7_MATH_1	447	451	PF00917	0.720
DOC_USP7_MATH_1	80	84	PF00917	0.638
DOC_WW_Pin1_4	119	124	PF00397	0.671
DOC_WW_Pin1_4	156	161	PF00397	0.672
DOC_WW_Pin1_4	173	178	PF00397	0.801
DOC_WW_Pin1_4	275	280	PF00397	0.650
DOC_WW_Pin1_4	295	300	PF00397	0.476
DOC_WW_Pin1_4	312	317	PF00397	0.543
DOC_WW_Pin1_4	415	420	PF00397	0.732
DOC_WW_Pin1_4	56	61	PF00397	0.633
DOC_WW_Pin1_4	86	91	PF00397	0.568
LIG_14-3-3_CanoR_1	116	121	PF00244	0.722
LIG_14-3-3_CanoR_1	125	129	PF00244	0.626
LIG_14-3-3_CanoR_1	340	346	PF00244	0.578
LIG_14-3-3_CanoR_1	448	457	PF00244	0.629
LIG_BIR_II_1	1	5	PF00653	0.554
LIG_BRCT_BRCA1_1	291	295	PF00533	0.653
LIG_BRCT_BRCA1_1	88	92	PF00533	0.589
LIG_deltaCOP1_diTrp_1	397	403	PF00928	0.674
LIG_EVH1_2	178	182	PF00568	0.692
LIG_FHA_1	250	256	PF00498	0.715
LIG_FHA_1	304	310	PF00498	0.750
LIG_FHA_1	313	319	PF00498	0.596
LIG_FHA_1	408	414	PF00498	0.487
LIG_FHA_1	427	433	PF00498	0.379
LIG_FHA_1	68	74	PF00498	0.644
LIG_FHA_2	276	282	PF00498	0.663
LIG_Integrin_RGD_1	185	187	PF01839	0.572
LIG_LIR_Apic_2	139	145	PF02991	0.849
LIG_LIR_Apic_2	221	227	PF02991	0.829
LIG_LIR_Apic_2	271	275	PF02991	0.600
LIG_LIR_Apic_2	293	299	PF02991	0.558
LIG_LIR_Gen_1	150	161	PF02991	0.583
LIG_LIR_Gen_1	264	272	PF02991	0.556
LIG_LIR_Gen_1	89	97	PF02991	0.566
LIG_LIR_Nem_3	150	156	PF02991	0.663
LIG_LIR_Nem_3	264	268	PF02991	0.550
LIG_LIR_Nem_3	398	404	PF02991	0.528
LIG_LIR_Nem_3	89	95	PF02991	0.566
LIG_SH2_CRK	142	146	PF00017	0.581
LIG_SH2_CRK	296	300	PF00017	0.555
LIG_SH2_NCK_1	224	228	PF00017	0.845
LIG_SH2_NCK_1	272	276	PF00017	0.607
LIG_SH2_PTP2	153	156	PF00017	0.602
LIG_SH2_SRC	224	227	PF00017	0.846
LIG_SH2_SRC	41	44	PF00017	0.599
LIG_SH2_STAP1	265	269	PF00017	0.553
LIG_SH2_STAT3	169	172	PF00017	0.597
LIG_SH2_STAT5	153	156	PF00017	0.724
LIG_SH2_STAT5	169	172	PF00017	0.636
LIG_SH2_STAT5	272	275	PF00017	0.559
LIG_SH3_1	142	148	PF00018	0.575
LIG_SH3_1	157	163	PF00018	0.504
LIG_SH3_2	13	18	PF14604	0.527
LIG_SH3_3	10	16	PF00018	0.540
LIG_SH3_3	107	113	PF00018	0.713
LIG_SH3_3	142	148	PF00018	0.575
LIG_SH3_3	157	163	PF00018	0.504
LIG_SH3_3	172	178	PF00018	0.821
LIG_SH3_3	311	317	PF00018	0.663
LIG_SH3_3	413	419	PF00018	0.722
LIG_SH3_3	473	479	PF00018	0.674
LIG_SH3_3	54	60	PF00018	0.588
LIG_SUMO_SIM_anti_2	257	262	PF11976	0.533
LIG_SUMO_SIM_par_1	254	259	PF11976	0.741
LIG_SUMO_SIM_par_1	286	294	PF11976	0.663
LIG_SUMO_SIM_par_1	423	429	PF11976	0.542
LIG_TRAF2_1	369	372	PF00917	0.615
LIG_WW_1	129	132	PF00397	0.559
MOD_CDK_SPxK_1	119	125	PF00069	0.589
MOD_CK1_1	103	109	PF00069	0.619
MOD_CK1_1	124	130	PF00069	0.831
MOD_CK1_1	152	158	PF00069	0.654
MOD_CK1_1	217	223	PF00069	0.620
MOD_CK1_1	290	296	PF00069	0.702
MOD_CK1_1	380	386	PF00069	0.639
MOD_CK1_1	6	12	PF00069	0.563
MOD_CK1_1	67	73	PF00069	0.688
MOD_CK1_1	83	89	PF00069	0.617
MOD_CK2_1	261	267	PF00069	0.716
MOD_CK2_1	268	274	PF00069	0.809
MOD_CK2_1	323	329	PF00069	0.593
MOD_CK2_1	366	372	PF00069	0.629
MOD_CK2_1	56	62	PF00069	0.589
MOD_Cter_Amidation	392	395	PF01082	0.461
MOD_GlcNHglycan	106	109	PF01048	0.658
MOD_GlcNHglycan	164	168	PF01048	0.735
MOD_GlcNHglycan	196	199	PF01048	0.825
MOD_GlcNHglycan	211	214	PF01048	0.580
MOD_GlcNHglycan	216	219	PF01048	0.481
MOD_GlcNHglycan	285	288	PF01048	0.653
MOD_GlcNHglycan	325	328	PF01048	0.644
MOD_GlcNHglycan	349	352	PF01048	0.684
MOD_GlcNHglycan	391	394	PF01048	0.609
MOD_GlcNHglycan	43	46	PF01048	0.622
MOD_GlcNHglycan	450	453	PF01048	0.532
MOD_GlcNHglycan	65	69	PF01048	0.647
MOD_GlcNHglycan	85	88	PF01048	0.642
MOD_GlcNHglycan	9	12	PF01048	0.558
MOD_GSK3_1	100	107	PF00069	0.800
MOD_GSK3_1	152	159	PF00069	0.813
MOD_GSK3_1	190	197	PF00069	0.674
MOD_GSK3_1	214	221	PF00069	0.665
MOD_GSK3_1	283	290	PF00069	0.797
MOD_GSK3_1	291	298	PF00069	0.645
MOD_GSK3_1	3	10	PF00069	0.564
MOD_GSK3_1	376	383	PF00069	0.779
MOD_GSK3_1	385	392	PF00069	0.701
MOD_GSK3_1	403	410	PF00069	0.460
MOD_GSK3_1	67	74	PF00069	0.669
MOD_GSK3_1	81	88	PF00069	0.521
MOD_GSK3_1	91	98	PF00069	0.580
MOD_N-GLC_1	218	223	PF02516	0.571
MOD_N-GLC_1	275	280	PF02516	0.694
MOD_N-GLC_1	303	308	PF02516	0.748
MOD_NEK2_1	104	109	PF00069	0.720
MOD_NEK2_1	268	273	PF00069	0.687
MOD_NEK2_1	289	294	PF00069	0.780
MOD_NEK2_1	339	344	PF00069	0.672
MOD_NEK2_1	346	351	PF00069	0.605
MOD_NEK2_1	91	96	PF00069	0.686
MOD_OFUCOSY	338	343	PF10250	0.691
MOD_PIKK_1	232	238	PF00454	0.672
MOD_PKA_1	30	36	PF00069	0.556
MOD_PKA_1	448	454	PF00069	0.497
MOD_PKA_2	124	130	PF00069	0.614
MOD_PKA_2	244	250	PF00069	0.748
MOD_PKA_2	30	36	PF00069	0.556
MOD_PKA_2	339	345	PF00069	0.566
MOD_PKA_2	447	453	PF00069	0.659
MOD_PKA_2	470	476	PF00069	0.691
MOD_Plk_1	36	42	PF00069	0.596
MOD_Plk_4	149	155	PF00069	0.743
MOD_Plk_4	291	297	PF00069	0.547
MOD_Plk_4	305	311	PF00069	0.670
MOD_Plk_4	470	476	PF00069	0.691
MOD_ProDKin_1	119	125	PF00069	0.671
MOD_ProDKin_1	156	162	PF00069	0.666
MOD_ProDKin_1	173	179	PF00069	0.801
MOD_ProDKin_1	275	281	PF00069	0.652
MOD_ProDKin_1	295	301	PF00069	0.474
MOD_ProDKin_1	312	318	PF00069	0.543
MOD_ProDKin_1	415	421	PF00069	0.736
MOD_ProDKin_1	56	62	PF00069	0.635
MOD_ProDKin_1	86	92	PF00069	0.569
TRG_DiLeu_BaLyEn_6	485	490	PF01217	0.722
TRG_ENDOCYTIC_2	153	156	PF00928	0.672
TRG_ENDOCYTIC_2	265	268	PF00928	0.552
TRG_ER_diArg_1	142	144	PF00400	0.604
TRG_ER_diArg_1	459	461	PF00400	0.475
TRG_Pf-PMV_PEXEL_1	136	141	PF00026	0.563
TRG_Pf-PMV_PEXEL_1	488	492	PF00026	0.702

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HCC2	Leishmania braziliensis	53%	100%
Q4QBP5	Leishmania major	73%	100%