Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AVL9_LEIMU

TriTrypDb:

LmxM.22.0350

Length:

250

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AVL9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AVL9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	148	152	PF00656	0.496
CLV_NRD_NRD_1	87	89	PF00675	0.694
CLV_NRD_NRD_1	95	97	PF00675	0.520
CLV_PCSK_KEX2_1	87	89	PF00082	0.690
CLV_PCSK_KEX2_1	94	96	PF00082	0.535
CLV_PCSK_SKI1_1	235	239	PF00082	0.558
DEG_APCC_DBOX_1	93	101	PF00400	0.588
DEG_Nend_UBRbox_2	1	3	PF02207	0.686
DOC_CKS1_1	176	181	PF01111	0.442
DOC_CYCLIN_RxL_1	182	192	PF00134	0.419
DOC_MAPK_gen_1	64	72	PF00069	0.652
DOC_MAPK_MEF2A_6	203	210	PF00069	0.532
DOC_MAPK_MEF2A_6	66	74	PF00069	0.657
DOC_PP1_RVXF_1	233	240	PF00149	0.551
DOC_USP7_MATH_1	33	37	PF00917	0.417
DOC_WW_Pin1_4	175	180	PF00397	0.442
LIG_14-3-3_CanoR_1	110	115	PF00244	0.616
LIG_14-3-3_CanoR_1	161	170	PF00244	0.504
LIG_14-3-3_CanoR_1	171	179	PF00244	0.483
LIG_14-3-3_CanoR_1	43	51	PF00244	0.492
LIG_14-3-3_CanoR_1	94	104	PF00244	0.604
LIG_BIR_III_2	14	18	PF00653	0.535
LIG_BRCT_BRCA1_1	149	153	PF00533	0.492
LIG_BRCT_BRCA1_1	235	239	PF00533	0.558
LIG_FHA_1	176	182	PF00498	0.575
LIG_FHA_1	190	196	PF00498	0.617
LIG_FHA_1	99	105	PF00498	0.523
LIG_FHA_2	114	120	PF00498	0.599
LIG_FHA_2	146	152	PF00498	0.500
LIG_FHA_2	228	234	PF00498	0.615
LIG_FHA_2	240	246	PF00498	0.473
LIG_FHA_2	45	51	PF00498	0.376
LIG_SH2_CRK	160	164	PF00017	0.594
LIG_SH2_STAP1	191	195	PF00017	0.671
LIG_SH2_STAT3	60	63	PF00017	0.535
LIG_SH2_STAT5	191	194	PF00017	0.670
LIG_SH2_STAT5	60	63	PF00017	0.535
LIG_SH3_3	201	207	PF00018	0.526
LIG_WRC_WIRS_1	20	25	PF05994	0.594
MOD_CDK_SPxxK_3	175	182	PF00069	0.447
MOD_CK1_1	113	119	PF00069	0.608
MOD_CK1_1	145	151	PF00069	0.591
MOD_CK1_1	3	9	PF00069	0.732
MOD_CK1_1	98	104	PF00069	0.524
MOD_CK2_1	113	119	PF00069	0.594
MOD_CK2_1	25	31	PF00069	0.421
MOD_CK2_1	44	50	PF00069	0.349
MOD_GlcNHglycan	10	13	PF01048	0.652
MOD_GlcNHglycan	2	5	PF01048	0.744
MOD_GlcNHglycan	75	79	PF01048	0.382
MOD_GSK3_1	131	138	PF00069	0.652
MOD_GSK3_1	140	147	PF00069	0.621
MOD_GSK3_1	161	168	PF00069	0.420
MOD_GSK3_1	25	32	PF00069	0.432
MOD_GSK3_1	76	83	PF00069	0.591
MOD_NEK2_1	159	164	PF00069	0.609
MOD_NEK2_1	189	194	PF00069	0.475
MOD_NEK2_1	239	244	PF00069	0.467
MOD_NEK2_1	74	79	PF00069	0.369
MOD_PIKK_1	113	119	PF00454	0.594
MOD_PIKK_1	76	82	PF00454	0.590
MOD_PK_1	108	114	PF00069	0.417
MOD_PKA_1	95	101	PF00069	0.566
MOD_PKA_2	170	176	PF00069	0.615
MOD_PKA_2	95	101	PF00069	0.566
MOD_Plk_1	131	137	PF00069	0.557
MOD_Plk_1	25	31	PF00069	0.421
MOD_Plk_4	19	25	PF00069	0.601
MOD_Plk_4	56	62	PF00069	0.620
MOD_ProDKin_1	175	181	PF00069	0.445
TRG_DiLeu_BaEn_3	18	24	PF01217	0.554
TRG_DiLeu_BaLyEn_6	179	184	PF01217	0.559
TRG_ENDOCYTIC_2	160	163	PF00928	0.600
TRG_ER_diArg_1	94	96	PF00400	0.601
TRG_Pf-PMV_PEXEL_1	182	186	PF00026	0.567
TRG_Pf-PMV_PEXEL_1	49	53	PF00026	0.510

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IE58	Leishmania donovani	81%	100%
A4HC84	Leishmania braziliensis	62%	95%
A4HZR3	Leishmania infantum	81%	100%
Q4QBW0	Leishmania major	80%	100%