Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AVL7_LEIMU

TriTrypDb:

LmxM.22.0330

Length:

1064

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AVL7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AVL7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	159	163	PF00656	0.706
CLV_C14_Caspase3-7	746	750	PF00656	0.455
CLV_C14_Caspase3-7	827	831	PF00656	0.671
CLV_C14_Caspase3-7	869	873	PF00656	0.511
CLV_NRD_NRD_1	151	153	PF00675	0.766
CLV_NRD_NRD_1	296	298	PF00675	0.744
CLV_NRD_NRD_1	326	328	PF00675	0.674
CLV_NRD_NRD_1	416	418	PF00675	0.771
CLV_NRD_NRD_1	465	467	PF00675	0.674
CLV_NRD_NRD_1	570	572	PF00675	0.735
CLV_PCSK_KEX2_1	151	153	PF00082	0.766
CLV_PCSK_KEX2_1	296	298	PF00082	0.729
CLV_PCSK_KEX2_1	326	328	PF00082	0.670
CLV_PCSK_KEX2_1	416	418	PF00082	0.771
CLV_PCSK_KEX2_1	465	467	PF00082	0.595
CLV_PCSK_KEX2_1	547	549	PF00082	0.767
CLV_PCSK_KEX2_1	570	572	PF00082	0.755
CLV_PCSK_KEX2_1	913	915	PF00082	0.501
CLV_PCSK_PC1ET2_1	547	549	PF00082	0.767
CLV_PCSK_PC1ET2_1	913	915	PF00082	0.501
CLV_PCSK_SKI1_1	151	155	PF00082	0.761
CLV_PCSK_SKI1_1	433	437	PF00082	0.784
CLV_PCSK_SKI1_1	609	613	PF00082	0.664
CLV_PCSK_SKI1_1	621	625	PF00082	0.423
CLV_PCSK_SKI1_1	860	864	PF00082	0.728
CLV_PCSK_SKI1_1	886	890	PF00082	0.642
DEG_APCC_DBOX_1	325	333	PF00400	0.681
DEG_Nend_UBRbox_2	1	3	PF02207	0.764
DEG_SCF_FBW7_1	153	158	PF00400	0.697
DEG_SCF_FBW7_1	75	80	PF00400	0.485
DEG_SCF_TRCP1_1	722	728	PF00400	0.611
DEG_SPOP_SBC_1	155	159	PF00917	0.700
DEG_SPOP_SBC_1	578	582	PF00917	0.677
DEG_SPOP_SBC_1	713	717	PF00917	0.681
DEG_SPOP_SBC_1	835	839	PF00917	0.532
DOC_ANK_TNKS_1	277	284	PF00023	0.527
DOC_CKS1_1	435	440	PF01111	0.791
DOC_CKS1_1	808	813	PF01111	0.660
DOC_CYCLIN_yCln2_LP_2	124	127	PF00134	0.508
DOC_MAPK_DCC_7	886	896	PF00069	0.573
DOC_MAPK_FxFP_2	355	358	PF00069	0.704
DOC_MAPK_gen_1	296	305	PF00069	0.761
DOC_MAPK_MEF2A_6	299	307	PF00069	0.613
DOC_MAPK_MEF2A_6	369	377	PF00069	0.593
DOC_PP2B_LxvP_1	124	127	PF13499	0.508
DOC_PP4_FxxP_1	195	198	PF00568	0.534
DOC_PP4_FxxP_1	301	304	PF00568	0.765
DOC_PP4_FxxP_1	355	358	PF00568	0.704
DOC_USP7_MATH_1	1027	1031	PF00917	0.497
DOC_USP7_MATH_1	140	144	PF00917	0.677
DOC_USP7_MATH_1	146	150	PF00917	0.625
DOC_USP7_MATH_1	19	23	PF00917	0.523
DOC_USP7_MATH_1	237	241	PF00917	0.793
DOC_USP7_MATH_1	306	310	PF00917	0.547
DOC_USP7_MATH_1	380	384	PF00917	0.587
DOC_USP7_MATH_1	425	429	PF00917	0.692
DOC_USP7_MATH_1	444	448	PF00917	0.530
DOC_USP7_MATH_1	479	483	PF00917	0.697
DOC_USP7_MATH_1	500	504	PF00917	0.583
DOC_USP7_MATH_1	52	56	PF00917	0.518
DOC_USP7_MATH_1	585	589	PF00917	0.799
DOC_USP7_MATH_1	597	601	PF00917	0.632
DOC_USP7_MATH_1	647	651	PF00917	0.686
DOC_USP7_MATH_1	688	692	PF00917	0.628
DOC_USP7_MATH_1	713	717	PF00917	0.681
DOC_USP7_MATH_1	743	747	PF00917	0.542
DOC_USP7_MATH_1	771	775	PF00917	0.659
DOC_USP7_MATH_1	782	786	PF00917	0.680
DOC_USP7_MATH_1	797	801	PF00917	0.561
DOC_USP7_MATH_1	829	833	PF00917	0.663
DOC_USP7_MATH_1	836	840	PF00917	0.548
DOC_USP7_MATH_1	990	994	PF00917	0.639
DOC_WW_Pin1_4	119	124	PF00397	0.522
DOC_WW_Pin1_4	151	156	PF00397	0.697
DOC_WW_Pin1_4	182	187	PF00397	0.798
DOC_WW_Pin1_4	215	220	PF00397	0.764
DOC_WW_Pin1_4	241	246	PF00397	0.706
DOC_WW_Pin1_4	269	274	PF00397	0.780
DOC_WW_Pin1_4	277	282	PF00397	0.653
DOC_WW_Pin1_4	290	295	PF00397	0.580
DOC_WW_Pin1_4	35	40	PF00397	0.670
DOC_WW_Pin1_4	434	439	PF00397	0.804
DOC_WW_Pin1_4	508	513	PF00397	0.725
DOC_WW_Pin1_4	727	732	PF00397	0.514
DOC_WW_Pin1_4	73	78	PF00397	0.653
DOC_WW_Pin1_4	807	812	PF00397	0.663
DOC_WW_Pin1_4	887	892	PF00397	0.723
DOC_WW_Pin1_4	900	905	PF00397	0.589
DOC_WW_Pin1_4	917	922	PF00397	0.500
DOC_WW_Pin1_4	997	1002	PF00397	0.527
LIG_14-3-3_CanoR_1	1004	1014	PF00244	0.564
LIG_14-3-3_CanoR_1	175	180	PF00244	0.786
LIG_14-3-3_CanoR_1	296	302	PF00244	0.762
LIG_14-3-3_CanoR_1	416	424	PF00244	0.811
LIG_14-3-3_CanoR_1	48	54	PF00244	0.607
LIG_14-3-3_CanoR_1	5	14	PF00244	0.678
LIG_14-3-3_CanoR_1	522	528	PF00244	0.752
LIG_14-3-3_CanoR_1	570	578	PF00244	0.526
LIG_14-3-3_CanoR_1	658	664	PF00244	0.611
LIG_14-3-3_CanoR_1	935	944	PF00244	0.562
LIG_Actin_WH2_2	479	495	PF00022	0.638
LIG_Actin_WH2_2	605	623	PF00022	0.666
LIG_BRCT_BRCA1_1	1024	1028	PF00533	0.659
LIG_BRCT_BRCA1_1	191	195	PF00533	0.578
LIG_BRCT_BRCA1_1	297	301	PF00533	0.765
LIG_BRCT_BRCA1_1	338	342	PF00533	0.699
LIG_BRCT_BRCA1_1	784	788	PF00533	0.734
LIG_BRCT_BRCA1_1	846	850	PF00533	0.517
LIG_Clathr_ClatBox_1	205	209	PF01394	0.556
LIG_DLG_GKlike_1	175	183	PF00625	0.702
LIG_FHA_1	1010	1016	PF00498	0.513
LIG_FHA_1	1058	1064	PF00498	0.755
LIG_FHA_1	120	126	PF00498	0.680
LIG_FHA_1	174	180	PF00498	0.712
LIG_FHA_1	215	221	PF00498	0.751
LIG_FHA_1	331	337	PF00498	0.759
LIG_FHA_1	532	538	PF00498	0.742
LIG_FHA_1	700	706	PF00498	0.677
LIG_FHA_1	841	847	PF00498	0.665
LIG_FHA_1	951	957	PF00498	0.545
LIG_FHA_2	1006	1012	PF00498	0.684
LIG_FHA_2	104	110	PF00498	0.761
LIG_FHA_2	1056	1062	PF00498	0.740
LIG_FHA_2	11	17	PF00498	0.601
LIG_FHA_2	825	831	PF00498	0.671
LIG_LIR_Apic_2	192	198	PF02991	0.540
LIG_LIR_Apic_2	298	304	PF02991	0.763
LIG_LIR_Apic_2	76	82	PF02991	0.487
LIG_LIR_Apic_2	877	883	PF02991	0.679
LIG_LIR_Gen_1	13	21	PF02991	0.602
LIG_LIR_Gen_1	362	373	PF02991	0.511
LIG_LIR_Gen_1	614	624	PF02991	0.718
LIG_LIR_Nem_3	1025	1031	PF02991	0.690
LIG_LIR_Nem_3	13	17	PF02991	0.603
LIG_LIR_Nem_3	362	368	PF02991	0.513
LIG_LIR_Nem_3	614	620	PF02991	0.728
LIG_LIR_Nem_3	785	791	PF02991	0.748
LIG_MYND_1	434	438	PF01753	0.786
LIG_NRBOX	482	488	PF00104	0.687
LIG_SH2_CRK	79	83	PF00017	0.490
LIG_SH2_STAT3	922	925	PF00017	0.498
LIG_SH2_STAT5	463	466	PF00017	0.793
LIG_SH2_STAT5	922	925	PF00017	0.638
LIG_SH2_STAT5	930	933	PF00017	0.724
LIG_SH3_2	273	278	PF14604	0.531
LIG_SH3_3	120	126	PF00018	0.725
LIG_SH3_3	168	174	PF00018	0.693
LIG_SH3_3	190	196	PF00018	0.576
LIG_SH3_3	225	231	PF00018	0.705
LIG_SH3_3	239	245	PF00018	0.777
LIG_SH3_3	270	276	PF00018	0.677
LIG_SH3_3	355	361	PF00018	0.585
LIG_SH3_3	372	378	PF00018	0.658
LIG_SH3_3	432	438	PF00018	0.782
LIG_SH3_3	798	804	PF00018	0.599
LIG_SH3_3	959	965	PF00018	0.590
LIG_SUMO_SIM_par_1	243	249	PF11976	0.530
LIG_SUMO_SIM_par_1	903	910	PF11976	0.595
LIG_SxIP_EBH_1	561	573	PF03271	0.602
LIG_TRAF2_1	198	201	PF00917	0.770
LIG_TRAF2_1	939	942	PF00917	0.765
LIG_WRC_WIRS_1	1028	1033	PF05994	0.668
LIG_WRC_WIRS_1	391	396	PF05994	0.713
MOD_CDK_SPxK_1	290	296	PF00069	0.672
MOD_CDK_SPxK_1	807	813	PF00069	0.659
MOD_CDK_SPxxK_3	290	297	PF00069	0.757
MOD_CDK_SPxxK_3	917	924	PF00069	0.585
MOD_CDK_SPxxK_3	997	1004	PF00069	0.528
MOD_CK1_1	1057	1063	PF00069	0.744
MOD_CK1_1	131	137	PF00069	0.677
MOD_CK1_1	138	144	PF00069	0.614
MOD_CK1_1	157	163	PF00069	0.566
MOD_CK1_1	182	188	PF00069	0.754
MOD_CK1_1	214	220	PF00069	0.686
MOD_CK1_1	240	246	PF00069	0.720
MOD_CK1_1	309	315	PF00069	0.744
MOD_CK1_1	330	336	PF00069	0.697
MOD_CK1_1	359	365	PF00069	0.758
MOD_CK1_1	395	401	PF00069	0.768
MOD_CK1_1	420	426	PF00069	0.754
MOD_CK1_1	429	435	PF00069	0.649
MOD_CK1_1	482	488	PF00069	0.687
MOD_CK1_1	491	497	PF00069	0.635
MOD_CK1_1	50	56	PF00069	0.684
MOD_CK1_1	580	586	PF00069	0.587
MOD_CK1_1	59	65	PF00069	0.679
MOD_CK1_1	691	697	PF00069	0.605
MOD_CK1_1	730	736	PF00069	0.673
MOD_CK1_1	744	750	PF00069	0.509
MOD_CK1_1	787	793	PF00069	0.681
MOD_CK1_1	822	828	PF00069	0.642
MOD_CK1_1	839	845	PF00069	0.671
MOD_CK1_1	887	893	PF00069	0.594
MOD_CK1_1	94	100	PF00069	0.761
MOD_CK1_1	993	999	PF00069	0.701
MOD_CK2_1	10	16	PF00069	0.600
MOD_CK2_1	103	109	PF00069	0.765
MOD_CK2_1	1055	1061	PF00069	0.739
MOD_CK2_1	207	213	PF00069	0.688
MOD_CK2_1	714	720	PF00069	0.718
MOD_CK2_1	935	941	PF00069	0.755
MOD_GlcNHglycan	140	143	PF01048	0.675
MOD_GlcNHglycan	148	151	PF01048	0.605
MOD_GlcNHglycan	16	20	PF01048	0.567
MOD_GlcNHglycan	308	311	PF01048	0.747
MOD_GlcNHglycan	386	389	PF01048	0.683
MOD_GlcNHglycan	445	449	PF01048	0.783
MOD_GlcNHglycan	450	453	PF01048	0.733
MOD_GlcNHglycan	49	52	PF01048	0.520
MOD_GlcNHglycan	493	496	PF01048	0.757
MOD_GlcNHglycan	582	585	PF01048	0.707
MOD_GlcNHglycan	587	590	PF01048	0.724
MOD_GlcNHglycan	599	602	PF01048	0.574
MOD_GlcNHglycan	624	627	PF01048	0.632
MOD_GlcNHglycan	672	675	PF01048	0.546
MOD_GlcNHglycan	684	689	PF01048	0.620
MOD_GlcNHglycan	693	696	PF01048	0.615
MOD_GlcNHglycan	716	719	PF01048	0.704
MOD_GlcNHglycan	722	725	PF01048	0.680
MOD_GlcNHglycan	738	741	PF01048	0.591
MOD_GlcNHglycan	768	772	PF01048	0.648
MOD_GlcNHglycan	784	787	PF01048	0.630
MOD_GlcNHglycan	805	808	PF01048	0.659
MOD_GlcNHglycan	815	818	PF01048	0.590
MOD_GlcNHglycan	819	822	PF01048	0.567
MOD_GlcNHglycan	838	841	PF01048	0.755
MOD_GlcNHglycan	876	879	PF01048	0.689
MOD_GlcNHglycan	909	912	PF01048	0.571
MOD_GlcNHglycan	93	96	PF01048	0.677
MOD_GlcNHglycan	938	941	PF01048	0.757
MOD_GlcNHglycan	972	975	PF01048	0.682
MOD_GSK3_1	1	8	PF00069	0.703
MOD_GSK3_1	1005	1012	PF00069	0.712
MOD_GSK3_1	1057	1064	PF00069	0.749
MOD_GSK3_1	130	137	PF00069	0.746
MOD_GSK3_1	15	22	PF00069	0.610
MOD_GSK3_1	151	158	PF00069	0.765
MOD_GSK3_1	175	182	PF00069	0.708
MOD_GSK3_1	185	192	PF00069	0.672
MOD_GSK3_1	207	214	PF00069	0.801
MOD_GSK3_1	233	240	PF00069	0.786
MOD_GSK3_1	253	260	PF00069	0.706
MOD_GSK3_1	328	335	PF00069	0.749
MOD_GSK3_1	359	366	PF00069	0.748
MOD_GSK3_1	380	387	PF00069	0.659
MOD_GSK3_1	392	399	PF00069	0.657
MOD_GSK3_1	423	430	PF00069	0.798
MOD_GSK3_1	444	451	PF00069	0.777
MOD_GSK3_1	452	459	PF00069	0.707
MOD_GSK3_1	478	485	PF00069	0.635
MOD_GSK3_1	52	59	PF00069	0.694
MOD_GSK3_1	573	580	PF00069	0.653
MOD_GSK3_1	647	654	PF00069	0.623
MOD_GSK3_1	659	666	PF00069	0.649
MOD_GSK3_1	684	691	PF00069	0.569
MOD_GSK3_1	725	732	PF00069	0.702
MOD_GSK3_1	73	80	PF00069	0.665
MOD_GSK3_1	767	774	PF00069	0.713
MOD_GSK3_1	803	810	PF00069	0.741
MOD_GSK3_1	813	820	PF00069	0.640
MOD_GSK3_1	835	842	PF00069	0.622
MOD_GSK3_1	89	96	PF00069	0.538
MOD_GSK3_1	896	903	PF00069	0.690
MOD_GSK3_1	98	105	PF00069	0.663
MOD_GSK3_1	993	1000	PF00069	0.645
MOD_N-GLC_1	1036	1041	PF02516	0.438
MOD_N-GLC_1	155	160	PF02516	0.681
MOD_N-GLC_1	214	219	PF02516	0.621
MOD_N-GLC_1	384	389	PF02516	0.715
MOD_N-GLC_1	396	401	PF02516	0.713
MOD_N-GLC_1	5	10	PF02516	0.508
MOD_N-GLC_2	467	469	PF02516	0.739
MOD_NEK2_1	1	6	PF00069	0.689
MOD_NEK2_1	1022	1027	PF00069	0.493
MOD_NEK2_1	129	134	PF00069	0.728
MOD_NEK2_1	135	140	PF00069	0.681
MOD_NEK2_1	179	184	PF00069	0.717
MOD_NEK2_1	189	194	PF00069	0.654
MOD_NEK2_1	220	225	PF00069	0.579
MOD_NEK2_1	258	263	PF00069	0.538
MOD_NEK2_1	368	373	PF00069	0.718
MOD_NEK2_1	415	420	PF00069	0.816
MOD_NEK2_1	531	536	PF00069	0.726
MOD_NEK2_1	642	647	PF00069	0.693
MOD_NEK2_1	775	780	PF00069	0.744
MOD_NEK2_1	792	797	PF00069	0.733
MOD_NEK2_1	819	824	PF00069	0.677
MOD_NEK2_1	896	901	PF00069	0.747
MOD_NEK2_1	967	972	PF00069	0.596
MOD_NEK2_1	978	983	PF00069	0.671
MOD_NEK2_2	364	369	PF00069	0.511
MOD_NEK2_2	699	704	PF00069	0.590
MOD_PIKK_1	1036	1042	PF00454	0.673
MOD_PIKK_1	223	229	PF00454	0.541
MOD_PIKK_1	237	243	PF00454	0.721
MOD_PIKK_1	5	11	PF00454	0.674
MOD_PIKK_1	513	519	PF00454	0.783
MOD_PIKK_1	531	537	PF00454	0.474
MOD_PKA_2	1003	1009	PF00069	0.691
MOD_PKA_2	179	185	PF00069	0.700
MOD_PKA_2	295	301	PF00069	0.680
MOD_PKA_2	336	342	PF00069	0.700
MOD_PKA_2	4	10	PF00069	0.741
MOD_PKA_2	415	421	PF00069	0.748
MOD_PKA_2	47	53	PF00069	0.493
MOD_PKA_2	521	527	PF00069	0.760
MOD_PKA_2	561	567	PF00069	0.756
MOD_PKA_2	640	646	PF00069	0.780
MOD_PKB_1	571	579	PF00069	0.593
MOD_Plk_1	1036	1042	PF00069	0.497
MOD_Plk_1	15	21	PF00069	0.750
MOD_Plk_1	199	205	PF00069	0.686
MOD_Plk_1	248	254	PF00069	0.695
MOD_Plk_1	327	333	PF00069	0.748
MOD_Plk_1	733	739	PF00069	0.746
MOD_Plk_1	761	767	PF00069	0.681
MOD_Plk_1	771	777	PF00069	0.597
MOD_Plk_4	10	16	PF00069	0.667
MOD_Plk_4	220	226	PF00069	0.808
MOD_Plk_4	253	259	PF00069	0.749
MOD_Plk_4	368	374	PF00069	0.737
MOD_Plk_4	482	488	PF00069	0.707
MOD_Plk_4	663	669	PF00069	0.695
MOD_Plk_4	67	73	PF00069	0.624
MOD_Plk_4	787	793	PF00069	0.748
MOD_Plk_4	819	825	PF00069	0.737
MOD_Plk_4	967	973	PF00069	0.575
MOD_ProDKin_1	119	125	PF00069	0.521
MOD_ProDKin_1	151	157	PF00069	0.697
MOD_ProDKin_1	182	188	PF00069	0.798
MOD_ProDKin_1	215	221	PF00069	0.763
MOD_ProDKin_1	241	247	PF00069	0.703
MOD_ProDKin_1	269	275	PF00069	0.778
MOD_ProDKin_1	277	283	PF00069	0.652
MOD_ProDKin_1	290	296	PF00069	0.582
MOD_ProDKin_1	35	41	PF00069	0.670
MOD_ProDKin_1	434	440	PF00069	0.805
MOD_ProDKin_1	508	514	PF00069	0.723
MOD_ProDKin_1	727	733	PF00069	0.513
MOD_ProDKin_1	73	79	PF00069	0.654
MOD_ProDKin_1	807	813	PF00069	0.664
MOD_ProDKin_1	887	893	PF00069	0.719
MOD_ProDKin_1	900	906	PF00069	0.590
MOD_ProDKin_1	917	923	PF00069	0.500
MOD_ProDKin_1	997	1003	PF00069	0.527
MOD_SUMO_for_1	681	684	PF00179	0.587
MOD_SUMO_rev_2	650	655	PF00179	0.624
MOD_SUMO_rev_2	855	862	PF00179	0.721
TRG_DiLeu_BaEn_1	858	863	PF01217	0.734
TRG_ER_diArg_1	151	153	PF00400	0.763
TRG_ER_diArg_1	296	299	PF00400	0.727
TRG_ER_diArg_1	415	417	PF00400	0.747
TRG_ER_diArg_1	431	434	PF00400	0.560
TRG_ER_diArg_1	569	571	PF00400	0.736

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IFD9	Leishmania donovani	80%	98%
A4HC83	Leishmania braziliensis	55%	98%
A4HZR1	Leishmania infantum	80%	98%
Q4QBW2	Leishmania major	80%	100%